Stanley S Franklin

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Is pulse pressure useful in predicting risk for coronary heart Disease? The Framingham heart study
    S S Franklin
    Heart Disease Prevention Program, University of California, Irvine, USA
    Circulation 100:354-60. 1999
  2. ncbi request reprint Ageing and hypertension: the assessment of blood pressure indices in predicting coronary heart disease
    S S Franklin
    Heart Disease Prevention Program, University of California, Irvine 92697, USA
    J Hypertens Suppl 17:S29-36. 1999
  3. ncbi request reprint Is there a preferred antihypertensive therapy for isolated systolic hypertension and reduced arterial compliance?
    S S Franklin
    UCI Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Curr Hypertens Rep 2:253-9. 2000
  4. ncbi request reprint Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart Study
    S S Franklin
    Preventive Cardiology Program, University of California, Irvine 92697, USA
    Circulation 103:1245-9. 2001
  5. ncbi request reprint Definition and epidemiology of hypertensive cardiovascular disease in women: the size of the problem
    Stanley S Franklin
    Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    J Hypertens Suppl 20:S3-5. 2002
  6. pmc Masked hypertension in diabetes mellitus: treatment implications for clinical practice
    Stanley S Franklin
    Heart Disease Prevention Program, Division of Cardiology, School of Medicine, University of California, Irvine, California, USA
    Hypertension 61:964-71. 2013
  7. ncbi request reprint Cardiovascular comorbidities and blood pressure control in stroke survivors
    Manoj Kesarwani
    Heart Disease Prevention Program, Division of Cardiology, Department ofMedicine, University of California, Irvine, California 92697 4101, USA
    J Hypertens 27:1056-63. 2009
  8. ncbi request reprint Trends in control of cardiovascular risk factors among US adults with type 2 diabetes from 1999 to 2010: comparison by prevalent cardiovascular disease status
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, Irvine, CA, USA
    Diab Vasc Dis Res 10:505-13. 2013
  9. pmc Comparison of demographic factors and cardiovascular risk factor control among U.S. adults with type 2 diabetes by insulin treatment classification
    Kalina Wong
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA
    J Diabetes Complications 26:169-74. 2012
  10. pmc Single versus combined blood pressure components and risk for cardiovascular disease: the Framingham Heart Study
    Stanley S Franklin
    Heart Disease Prevention Program, Department of Medicine, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Circulation 119:243-50. 2009

Detail Information

Publications53

  1. ncbi request reprint Is pulse pressure useful in predicting risk for coronary heart Disease? The Framingham heart study
    S S Franklin
    Heart Disease Prevention Program, University of California, Irvine, USA
    Circulation 100:354-60. 1999
    ..We examined whether PP adds useful information for predicting coronary heart disease (CHD) in the population-based Framingham Heart Study...
  2. ncbi request reprint Ageing and hypertension: the assessment of blood pressure indices in predicting coronary heart disease
    S S Franklin
    Heart Disease Prevention Program, University of California, Irvine 92697, USA
    J Hypertens Suppl 17:S29-36. 1999
    ..To determine whether pulse pressure (PP), diastolic blood pressure (DBP), systolic blood pressure (SBP), or mean arterial pressure (MAP) is the superior haemodynamic predictor for the risk of coronary heart disease (CHD)...
  3. ncbi request reprint Is there a preferred antihypertensive therapy for isolated systolic hypertension and reduced arterial compliance?
    S S Franklin
    UCI Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Curr Hypertens Rep 2:253-9. 2000
    ....
  4. ncbi request reprint Does the relation of blood pressure to coronary heart disease risk change with aging? The Framingham Heart Study
    S S Franklin
    Preventive Cardiology Program, University of California, Irvine 92697, USA
    Circulation 103:1245-9. 2001
    ..We examined the relative importance of diastolic (DBP), systolic (SBP) and pulse pressure (PP) as predictors of coronary heart disease (CHD) risk in different age groups of Framingham Heart Study participants...
  5. ncbi request reprint Definition and epidemiology of hypertensive cardiovascular disease in women: the size of the problem
    Stanley S Franklin
    Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    J Hypertens Suppl 20:S3-5. 2002
    ..This short review will highlight gender differences and similarities as noted in recent observational studies and intervention trials...
  6. pmc Masked hypertension in diabetes mellitus: treatment implications for clinical practice
    Stanley S Franklin
    Heart Disease Prevention Program, Division of Cardiology, School of Medicine, University of California, Irvine, California, USA
    Hypertension 61:964-71. 2013
    ..Importantly, many hypertensive diabetics when receiving antihypertensive therapy can present with normalized conventional and elevated ambulatory blood pressure that mimics masked hypertension...
  7. ncbi request reprint Cardiovascular comorbidities and blood pressure control in stroke survivors
    Manoj Kesarwani
    Heart Disease Prevention Program, Division of Cardiology, Department ofMedicine, University of California, Irvine, California 92697 4101, USA
    J Hypertens 27:1056-63. 2009
    ..To examine the association of cardiovascular(CV) comorbidities with the likelihood of being a stroke survivor and to determine the prevalence, treatment, and control of hypertension in this population...
  8. ncbi request reprint Trends in control of cardiovascular risk factors among US adults with type 2 diabetes from 1999 to 2010: comparison by prevalent cardiovascular disease status
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, Irvine, CA, USA
    Diab Vasc Dis Res 10:505-13. 2013
    ..Whether CVD risk factors have improved in those with DM with and without CVD is not established. We compared risk factor levels and goal attainment in US adults with diabetes with and without CVD...
  9. pmc Comparison of demographic factors and cardiovascular risk factor control among U.S. adults with type 2 diabetes by insulin treatment classification
    Kalina Wong
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA
    J Diabetes Complications 26:169-74. 2012
    ..We examined DM control, risk factors, and comorbidities among U.S. persons according to insulin treatment status...
  10. pmc Single versus combined blood pressure components and risk for cardiovascular disease: the Framingham Heart Study
    Stanley S Franklin
    Heart Disease Prevention Program, Department of Medicine, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Circulation 119:243-50. 2009
    ..We compared systolic BP (SBP) and diastolic BP (DBP) versus pulse pressure (PP) and mean arterial pressure (MAP) combined and each of these 4 BP components alone in predicting CVD events...
  11. doi request reprint Global cardiovascular risk associated with hypertension and extent of treatment and control according to risk group
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, California, USA
    Am J Hypertens 25:561-7. 2012
    ..We examined CVD risk distribution and treatment and control patterns according to risk group...
  12. ncbi request reprint Predictors of new-onset diastolic and systolic hypertension: the Framingham Heart Study
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, C240 Medical Sciences, Irvine, CA 92697, USA
    Circulation 111:1121-7. 2005
    ..We examined the relations of blood pressure (BP) and clinical risk factors to the new onset of the 3 forms of hypertension...
  13. ncbi request reprint Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
    Shaista Malik
    Heart Disease Prevention Program, University of California, Irvine 92697, USA
    Circulation 110:1245-50. 2004
    ..We examined the impact of MetS on CHD, CVD, and overall mortality among US adults...
  14. doi request reprint Efficacy and safety of irbesartan/HCTZ in severe hypertension according to cardiometabolic factors
    Stanley S Franklin
    Department of Medicine, University of California, Irvine, CA, USA
    J Clin Hypertens (Greenwich) 12:487-94. 2010
    ..No excess of prespecified events was noted. Thus, initial treatment with irbesartan/hydrochlorothiazide was rapidly effective in high-risk, difficult-to-treat, severely hypertensive patients...
  15. ncbi request reprint Hypertension in older people: part 1
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, Irvine, Irvine, CA 92697, USA
    J Clin Hypertens (Greenwich) 8:444-9. 2006
    ....
  16. ncbi request reprint Inadequate control of hypertension in US adults with cardiovascular disease comorbidities in 2003-2004
    Nathan D Wong
    Heart Disease Prevention Program, Department of Medicine, University of California, C240 Medical Sciences, Irvine, CA 92697, USA
    Arch Intern Med 167:2431-6. 2007
    ....
  17. doi request reprint Global cardiovascular disease risk assessment in United States adults with diabetes
    Nathan D Wong
    Heart Disease Prevention Program, Division of Cardiology, University of California, 112 Sprague Hall, Irvine, CA 92697, USA
    Diab Vasc Dis Res 9:146-52. 2012
    ..Diabetes mellitus (DM) is often considered a risk equivalent for cardiovascular disease (CVD); however, the variation in CVD risk in adults with DM has not been described...
  18. ncbi request reprint Impact of C-reactive protein on the likelihood of peripheral arterial disease in United States adults with the metabolic syndrome, diabetes mellitus, and preexisting cardiovascular disease
    John D Vu
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, School of Medicine, Irvine, California, USA
    Am J Cardiol 96:655-8. 2005
    ..6, 95% confidence interval 2.2 to 34.0, p = 0.001). In conclusion, the likelihood of PAD in US adults with MS and DM is enhanced by elevated CRP levels...
  19. ncbi request reprint Coronary heart disease events preventable by control of blood pressure and lipids in US adults with hypertension
    Victor A Lopez
    Heart Disease Prevention Program, Division of Cardiology, Department of Medicine, University of California, Irvine, CA 92697, USA
    J Clin Hypertens (Greenwich) 9:436-43. 2007
    ..The authors' results demonstrate that combined control of BP and lipid levels may prevent the majority of CHD events in Americans with HTN...
  20. ncbi request reprint Arterial stiffness: is it ready for prime time?
    Stanley S Franklin
    Heart Disease Prevention Program, C 240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Curr Cardiol Rep 9:462-9. 2007
    ..This article asks the question: How useful are PWV and PWA, when compared with traditional measurement of blood pressure components, as biomarkers of CV disease?..
  21. ncbi request reprint Preventing coronary events by optimal control of blood pressure and lipids in patients with the metabolic syndrome
    Nathan D Wong
    Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, CA 92697, USA
    Am J Cardiol 91:1421-6. 2003
    ..6% for women; control to optimal levels resulted in preventing 80.5% and 82.1% of events, respectively. Thus, many CHD events in patients with MetS may be preventable by nominal or optimal control of lipids and/or blood pressure...
  22. ncbi request reprint Systolic blood pressure: it's time to take control
    Stanley S Franklin
    Department of Medicine, Heart Disease Prevention Program, University of California, Irvine, California, USA
    Am J Hypertens 17:49S-54S. 2004
    ..Improving patient outcomes relies on antihypertensive therapy that appropriately addresses control of SBP and pulse pressure, underscoring the importance of therapeutic options that effectively reduce arterial stiffness...
  23. pmc Significance of white-coat hypertension in older persons with isolated systolic hypertension: a meta-analysis using the International Database on Ambulatory Blood Pressure Monitoring in Relation to Cardiovascular Outcomes population
    Stanley S Franklin
    Heart Disease Prevention Program, Division of Cardiology, School of Medicine, University of California, Irvine, CA, USA
    Hypertension 59:564-71. 2012
    ..Therefore, one should be cautious in applying the term "white-coat hypertension" to persons receiving antihypertensive treatment...
  24. ncbi request reprint Hypertension in older people: part 2
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, Irvine, 92697, USA
    J Clin Hypertens (Greenwich) 8:521-5. 2006
    ..Reaching target systolic blood pressure levels most often requires the use of polypharmacy that includes a diuretic and perhaps specific agents that target arterial stiffness and early wave reflection...
  25. ncbi request reprint Blood pressure categories, hypertensive subtypes, and the metabolic syndrome
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, Irvine, California 92697, USA
    J Hypertens 24:2009-16. 2006
    ..Elevated blood pressure (BP) is one element of metabolic syndrome (MetS); however, the relation of various BP categories and hypertension subtypes to the likelihood of having MetS is not well defined...
  26. doi request reprint Elderly hypertensives: how are they different?
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
    J Clin Hypertens (Greenwich) 14:779-86. 2012
    ..The emphasis will be on the multiple ways that increased artery stiffness affects the natural history and clinical manifestations of hypertension in the elderly...
  27. doi request reprint The significance of low DBP in US adults with isolated systolic hypertension
    Stanley S Franklin
    The Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, California, USA
    J Hypertens 29:1101-8. 2011
    ....
  28. ncbi request reprint Cardiovascular morbidity and mortality in hypertensive patients with lower versus higher risk: a LIFE substudy
    Stanley S Franklin
    Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
    Hypertension 46:492-9. 2005
    ..In conclusion, losartan compared with atenolol reduces the risk of stroke, new-onset diabetes, and new-onset atrial fibrillation in the LRG and the HRG...
  29. ncbi request reprint Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) III
    S S Franklin
    Heart Disease Prevention Program, University of California, Irvine, CA 92697, USA
    Hypertension 37:869-74. 2001
    ..Better awareness of this middle-aged and older high-risk group and more aggressive antihypertensive therapy are necessary to address this treatment gap...
  30. ncbi request reprint Preventing heart disease by controlling hypertension: impact of hypertensive subtype, stage, age, and sex
    Nathan D Wong
    Heart Disease Prevention Program, University of California, Irvine, Calif 92697, USA
    Am Heart J 145:888-95. 2003
    ..Hypertension is related to significant morbidity and mortality rates from coronary heart disease (CHD). This report examines the relative and absolute impact on risk for CHD by controlling hypertension to high normal and optimal levels...
  31. doi request reprint Initial combination therapy for rapid and effective control of moderate and severe hypertension
    S S Franklin
    Department of Medicine, Medical Sciences I, College of Medicine, University of California, Irvine, CA 92697, USA
    J Hum Hypertens 23:4-11. 2009
    ....
  32. ncbi request reprint Blood pressure and cardiovascular disease: what remains to be achieved?
    S S Franklin
    Heart Disease Prevention Program, University of California, Irvine 92697, USA
    J Hypertens Suppl 19:S3-8. 2001
    ..Hypertensive cardiovascular disease represents a world-wide public health challenge that can be solved only by new innovative measures aimed at both prevention and treatment...
  33. ncbi request reprint Pulse pressure as a risk factor
    Stanley S Franklin
    UCI Heart Disease Prevention Program, C240 Medical Sciences, University of California, Irvine, California 92697, USA
    Clin Exp Hypertens 26:645-52. 2004
    ....
  34. ncbi request reprint Age-dependent associations between blood pressure and coronary artery calcification in asymptomatic adults
    Lawrence F Bielak
    Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, 48104 3028, USA
    J Hypertens 22:719-25. 2004
    ..The age-dependent roles of the components of blood pressure (BP) in the development of coronary artery calcification (CAC) are poorly understood...
  35. ncbi request reprint beta-Blockers in hypertension-the emperor has no clothes: an open letter to present and prospective drafters of new guidelines for the treatment of hypertension
    Franz H Messerli
    Ochsner Clinic Foundation, New Orleans, Louisiana 70121, USA
    Am J Hypertens 16:870-3. 2003
    ....
  36. ncbi request reprint Arterial stiffness and hypertension: a two-way street?
    Stanley S Franklin
    Hypertension 45:349-51. 2005
  37. ncbi request reprint Efficacy and safety of irbesartan/HCTZ combination therapy as initial treatment for rapid control of severe hypertension
    Joel M Neutel
    Orange County Heart Institute and Research Center, 14351 Myford Road, Tustin, CA 92780, USA
    J Clin Hypertens (Greenwich) 8:850-7; quiz 858-9. 2006
    ..7 mm Hg and 9.7 mm Hg (P<.0001). Greater and more rapid BP reduction with irbesartan/HCTZ was achieved without additional side effects...
  38. ncbi request reprint Age-specific relevance of usual blood pressure to vascular mortality
    Stanley S Franklin
    Lancet 361:1389; author reply 1391-2. 2003
  39. ncbi request reprint Cardiovascular risk evaluation: an inexact science
    Stanley S Franklin
    J Hypertens 20:2127-30. 2002
  40. ncbi request reprint Do diabetes and hypertension interact to accelerate vascular ageing?
    Stanley S Franklin
    J Hypertens 20:1693-6. 2002
  41. ncbi request reprint How important is pulse pressure as a predictor of cardiovascular risk?
    Stanley S Franklin
    Hypertension 39:E12-3. 2002
  42. ncbi request reprint Nitric oxide and the regulation of large artery stiffness: from physiology to pharmacology
    Ian B Wilkinson
    Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Hypertension 44:112-6. 2004
  43. ncbi request reprint Clinical trials in hypertension
    Franz H Messerli
    JAMA 296:1463; author reply 1464-5. 2006
  44. ncbi request reprint The nonpharmacologic treatment of hypertension: how effective is it? An update
    Marvin Moser
    J Clin Hypertens (Greenwich) 9:209-16. 2007
    ....
  45. ncbi request reprint Hypertension management: results of a new national survey for the hypertension education foundation: Harris interactive
    Marvin Moser
    Hypertension Education Foundation, Inc, Scarsdale, NY 10583, USA
    J Clin Hypertens (Greenwich) 9:316-23. 2007
    ..The survey suggests a high degree of risk awareness and treatment, and what appears to be an increase in control rates among hypertensive patients...
  46. ncbi request reprint Prevention of stroke and myocardial infarction by amlodipine and Angiotensin receptor blockers: a quantitative overview
    Ji Guang Wang
    Centre for Epidemiological Studies and Clinical Trials, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China
    Hypertension 50:181-8. 2007
    ..01) for stroke in trials involving an amlodipine group. In conclusion, blood pressure differences largely accounted for cardiovascular outcome...
  47. ncbi request reprint Increased stroke volume and aortic stiffness contribute to isolated systolic hypertension in young adults
    Carmel M McEniery
    Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Hypertension 46:221-6. 2005
    ..Long-term follow-up of these individuals is now required to determine whether they are at increased risk compared with age-matched normotensive individuals...
  48. ncbi request reprint Hypertension control: still not there-how to select the right add-on therapy to reach goal blood pressures
    Joel M Neutel
    Orange County Research Center, Tustin, CA, USA
    J Clin Hypertens (Greenwich) 9:889-96. 2007
    ..The authors maintained full control of the discussion and the resulting content of this article...
  49. ncbi request reprint Metabolic syndrome is associated with aortic stiffness in untreated essential hypertension
    Giuseppe Schillaci
    University of Perugia, Perugia, Italy
    Hypertension 45:1078-82. 2005
    ..Central, but not general, adiposity is an important determinant of aortic stiffness in hypertension...
  50. ncbi request reprint Systolic and diastolic blood pressure lowering as determinants of cardiovascular outcome
    Ji Guang Wang
    Study Coordinating Centre, Hypertension and Cardiovascular Rehabilitation Unit, Department of Molecular and Cardiovascular Research, University of Leuven, Belgium
    Hypertension 45:907-13. 2005
    ..These findings remained consistent if the achieved DBP averaged <70 mm Hg. In conclusion, our overview suggests that antihypertensive drug treatment improves outcome mainly through lowering of SBP...
  51. ncbi request reprint Relation between renal function within the normal range and central and peripheral arterial stiffness in hypertension
    Giuseppe Schillaci
    Unit of Internal Medicine, Angiology and Arteriosclerosis, University of Perugia, Perugia, Italy
    Hypertension 48:616-21. 2006
    ..These relations are in part independent from the effect of several confounders, including age, sex, and blood pressure values...
  52. ncbi request reprint Systolic hypertension: an overview
    Todd F Griffith
    Duke Institute of Renal Outcomes Research and Health Policy, Department of Medicine, Duke University Medical Center, Durham, NC, USA
    Am Heart J 149:769-75. 2005