Research Topics
Genomes and GenesSpecies | Gary M FranklinSummaryAffiliation: University of Washington Country: USA Publications
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Publications
Prediction of chronic disability in work-related musculoskeletal disorders: a prospective, population-based studyJudith A Turner
Departments of Psychiatry and Behavioral Sciences and Rehabilitation Medicine, University of Washington School of Medicine, Box 356560, Seattle, WA, 98195 6560, USA
BMC Musculoskelet Disord 5:14. 2004..2. Proportional hazards regression models will be constructed to determine the best combination of predictors of work disability duration at one year. Regression models will also be developed for the secondary outcomes...
Device evaluation and coverage policy in workers' compensation: examples from Washington StateG M Franklin
University of Washington School of Public Health and Community Medicine, Seattle, USA
Am J Manag Care 4:SP178-86. 1998..To prevent ever-rising costs, we need to increase provider education and patient education and consent, involve the state medical society in coverage policy, and collect relevant outcomes data from healthcare providers...- Opioid dosing trends and mortality in Washington State workers' compensation, 1996-2002Gary M Franklin
Department of Occupational and Environmental Health Sciences, Occupational Epidemiology and Health Outcomes Program, University of Washington School of Public Health and Community Medicine, Seattle, Washington 98103, USA
Am J Ind Med 48:91-9. 2005..These policy changes occurred despite scanty scientific evidence that chronic use of opioids was safe and effective... 
Early opioid prescription and subsequent disability among workers with back injuries: the Disability Risk Identification Study CohortGary M Franklin
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98103, USA
Spine (Phila Pa 1976) 33:199-204. 2008..Prospective, population-based cohort study...- Opioid use for chronic low back pain: A prospective, population-based study among injured workers in Washington state, 2002-2005Gary M Franklin
Departments of Environmental and Occupational Health Sciences, University of Washington, Seattle, USA
Clin J Pain 25:743-51. 2009..To determine (1) the natural history of prescription opioid use, (2) the predictors of long-term opioid use, and (3) the association between opioid dose and pain and function in a large cohort of workers with recent back injuries... - Outcome of surgery for thoracic outlet syndrome in Washington state workers' compensationG M Franklin
Department of Environmental Health, University of Washington School of Public Health and Community Medicine, Seattle, USA
Neurology 54:1252-7. 2000..To determine the predictors of outcome of thoracic outlet syndrome (TOS) surgery in a population-based cohort of injured workers... - Policy-relevant research: when does it matter?Gary M Franklin
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, 98103, USA
NeuroRx 1:356-62. 2004.... - Occupational factors and risk of Parkinson's disease: A population-based case-control studyJordan A Firestone
Department of Neurology, University of Washington, Seattle, USA
Am J Ind Med 53:217-23. 2010..Parkinson's disease (PD) has been associated with various workplace factors, but the evidence is inconsistent... - Calcium channel blockers and beta-blockers in relation to Parkinson's diseaseThanh G N Ton
Department of Epidemiology, University of Washington, Box 357236, Seattle, WA 98195 7326, USA
Parkinsonism Relat Disord 13:165-9. 2007..The weakness of these associations and the absence of additional influence of dose or duration of use argue against any causal interpretation... - 5' and 3' region variability in the dopamine transporter gene (SLC6A3), pesticide exposure and Parkinson's disease risk: a hypothesis-generating studySamir N P Kelada
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98105, USA
Hum Mol Genet 15:3055-62. 2006..66 (95% CI: 1.73-18.53). Thus, allelic variants in SLC6A3, which affect gene expression, are associated with PD in this population and may interact with occupational pesticide exposure to increase PD risk... - The functional polymorphism of the hemoglobin-binding protein haptoglobin influences susceptibility to idiopathic Parkinson's diseasePaola Costa-Mallen
Department of Laboratory Medicine, University of Washington, Seattle, Washington 98104, USA
Am J Med Genet B Neuropsychiatr Genet 147:216-22. 2008..To our knowledge, this is the first study that investigates the association of Hp genotypes with the risk of PD... - Work-related carpal tunnel syndrome in Washington State workers' compensation: utilization of surgery and the duration of lost workWilliam E Daniell
Department of Environmental and Occupational Health Sciences, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195 7234, USA
Am J Ind Med 52:931-42. 2009..Work-related carpal tunnel syndrome (CTS) is a leading cause of lengthy disability... - Dietary fats, cholesterol and iron as risk factors for Parkinson's diseaseKaren M Powers
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98195 7234, USA
Parkinsonism Relat Disord 15:47-52. 2009..Epidemiologic findings suggest that dietary components may contribute to the etiology of Parkinson's disease (PD). This population-based case-control study evaluated PD risk and dietary intake of fats, cholesterol and iron... - Development of a brief questionnaire to predict long-term disabilityDeborah Fulton-Kehoe
School of Public Health and Community Medicine, Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98103, USA
J Occup Environ Med 50:1042-52. 2008..To develop a brief worker-completed questionnaire for use soon after a work-related back injury to assess risk of long-term work disability... - Nurse practitioners as attending providers for injured workers: evaluating the effect of role expansion on disability and costsJeanne M Sears
Department of Health Services, School of Nursing, University of Washington, Seattle, Washington 98195, USA
Med Care 45:1154-61. 2007..This legislation authorized NPs to independently perform most functions of an attending physician... - Nonsteroidal anti-inflammatory drugs and risk of Parkinson's diseaseThanh G Ton
Department of Epidemiology, University of Washington, Seattle, Washington 98195, USA
Mov Disord 21:964-9. 2006..Our results provide only limited support for the hypothesis that use of aspirin may reduce the risk of this disease, and no indication of protection from other NSAIDs... - Factors associated with early magnetic resonance imaging utilization for acute occupational low back pain: a population-based study from Washington State workers' compensationJanessa M Graves
Harborview Injury Prevention and Research Center, Department of Pediatrics, School of Medicine, University of Washington, Seattle, WA 98104, USA
Spine (Phila Pa 1976) 37:1708-18. 2012..A population-based, prospective cohort study... - Early imaging for acute low back pain: one-year health and disability outcomes among Washington State workersJanessa M Graves
Harborview Injury Prevention and Research Center, Department of Pediatrics, School of Medicine, University of Washington, Seattle, WA, USA
Spine (Phila Pa 1976) 37:1617-27. 2012..A population-based, prospective cohort study... - Environmental tobacco smoke and Parkinson's diseaseSusan Searles Nielsen
University of Washington, Department of Environmental and Occupational Health Sciences, Seattle, Washington 98195 7234, USA
Mov Disord 27:293-6. 2012..Parkinson's disease is inversely associated with cigarette smoking, but its relation with passive smoking or environmental tobacco smoke exposure is rarely examined... - Expanding the role of nurse practitioners: effects on rural access to care for injured workersJeanne M Sears
Department of Health Services, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USA
J Rural Health 24:171-8. 2008..SHB 1691 authorized NPs to independently perform most functions of an attending physician... - Nurse practitioners as attending providers for workers with uncomplicated back injuries: using administrative data to evaluate quality and process of careJeanne M Sears
Department of Health Services, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195, USA
J Occup Environ Med 49:900-8. 2007.... - Diabetes, smoking, and other medical conditions in relation to Parkinson's disease riskKaren M Powers
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, 98195-7234, USA
Parkinsonism Relat Disord 12:185-9. 2006..However, among diabetics, the PD risk was especially reduced in non-smoking men (OR = 0.09, 95% CI = 0.02, 0.44). Other medical conditions showed no strong relations with PD... - Work-related carpal tunnel syndrome in Washington State workers' compensation: temporal trends, clinical practices, and disabilityWilliam E Daniell
Department of Environmental and Occupational Health Sciences, School of Public Health and Community Medicine, University of Washington, Seattle, Washington, USA
Am J Ind Med 48:259-69. 2005..Work-related carpal tunnel syndrome (CTS) is a leading cause of disability. There is a need for information about temporal trends, clinical practices, and treatment outcomes... - Dopamine transporter (SLC6A3) 5' region haplotypes significantly affect transcriptional activity in vitro but are not associated with Parkinson's diseaseSamir N Kelada
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington 98105, USA
Pharmacogenet Genomics 15:659-68. 2005..In addition, our findings provide further evidence supporting an association of PD with the VNTR polymorphism... - Measuring work disability: what can administrative data tell us about patient outcomes?Deborah Fulton-Kehoe
Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA 98103, USA
J Occup Environ Med 49:651-8. 2007..The purpose of this study was to assess the association between administrative measures of work disability and self-reported work, pain, and functional status... - Magnetic resonance imaging compared with electrodiagnostic studies in patients with suspected carpal tunnel syndrome: predicting symptoms, function, and surgical benefit at 1 yearJeffrey G Jarvik
Department of Radiology, University of Washington, Seattle, WA 98195, USA
J Neurosurg 108:541-50. 2008.... - Bending the prescription opioid dosing and mortality curves: impact of the Washington State opioid dosing guidelineGary M Franklin
Departments of Environmental and Occupational Health Sciences, Neurology, and Health Services, University of Washington School of Public Health, Seattle, WA 98109, USA
Am J Ind Med 55:325-31. 2012..We assessed changes in opioid dosing patterns and opioid-related mortality in the Washington State (WA) workers' compensation system following implementation of a specific WA opioid dosing guideline in April, 2007... - Lumbar fusion outcomes in Washington State workers' compensationSham Maghout Juratli
Occupational Epidemiology and Health Outcomes Program, University of Washington, School of Public Health and Community Medicine, Seattle, WA 98103 9058, USA
Spine (Phila Pa 1976) 31:2715-23. 2006..Retrospective population-based cohort study... - A communitywide intervention to improve outcomes and reduce disability among injured workers in Washington StateThomas M Wickizer
Department of Health Services, Box 357660, University of Washington, Seattle, WA 98175 7660, USA
Milbank Q 82:547-67, table of contents. 2004..Furthermore, collaborating with university researchers may help enhance the scientific rigor of the quality improvement initiative and create more opportunities for a successful evaluation... - Genotype and age at Parkinson disease diagnosisSusan Searles Nielsen
University of Washington, Department of Environmental and Occupational Health Sciences Seattle, WA, USA
Int J Mol Epidemiol Genet 4:61-9. 2013..These results await confirmation in other series of incident cases, but suggest that selected genes and environmental exposures may influence PD diagnosis age... - Multidisciplinary pain center outcomes in Washington State Workers' CompensationJames P Robinson
University of Washington Pain Center, Seattle, Washington, USA
J Occup Environ Med 46:473-8. 2004..At 4.6 years follow up, there was no evidence that pain center treatment affects either disability status or clinical status of injured workers... - Gender difference in the interaction of smoking and monoamine oxidase B intron 13 genotype in Parkinson's diseaseSamir N Kelada
Department of Environmental Health, University of Washington, Seattle 98195, USA
Neurotoxicology 23:515-9. 2002..These results suggest that a strong gender difference exists with respect to the modifying effect of MAO-B genotype on the smoking association with PD... - DNA sequence analysis of monoamine oxidase B gene coding and promoter regions in Parkinson's disease cases and unrelated controlsPaola Costa-Mallen
Department of Environmental and Occupational Health Sciences, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195 6099, USA
Mov Disord 19:76-83. 2004..5%, but it was not associated with PD risk. No commonly occurring (>10%) polymorphisms were found in the exons or the intronic sequences flanking the exons, although several rare variants were detected in the coding and promoter regions... - Mortality after lumbar fusion surgerySham Maghout Juratli
Division of Occupational and Environmental Medicine, Wayne State University School of Medicine, Detroit, MI, USA
Spine (Phila Pa 1976) 34:740-7. 2009..Retrospective population-based cohort study... - Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intakeHarvey Checkoway
University of Washington, School of Public Health and Community Medicine, Department of Environmental Health, Seattle, WA 98195, USA
Am J Epidemiol 155:732-8. 2002..4, 95% CI: 0.2, 0.9) and two or more cola drinks/day (OR = 0.6, 95% CI: 0.3, 1.4). The associations for tea and cola drinks were not confounded by smoking or coffee consumption... - Increased reporting of occupational hearing loss: workers' compensation in Washington State, 1984-1998William E Daniell
Department of Environmental Health, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195, USA
Am J Ind Med 42:502-10. 2002..Workers' compensation claims for hearing loss increased two-fold during 1984-1991 in Washington State... - No associations between Parkinson's disease and polymorphisms of the quinone oxidoreductase (NQO1, NQO2) genesStarlyn Okada
Department of Environmental and Occupational Health Sciences, University of Washington, Box 357234, Seattle, WA 98195 7234, USA
Neurosci Lett 375:178-80. 2005..No associations were detected for either gene variant or for any allele combinations... - Compliance with electrodiagnostic guidelines for patients undergoing carpal tunnel releaseSeneca Storm
Department of Rehabilitation Medicine, University of Washington, Seattle, WA 98195, USA
Arch Phys Med Rehabil 86:8-11; quiz 180. 2005..Policymakers should consider mandating an appropriate electrodiagnostic test before approving CTR... - Glutathione S-transferase M1, T1, and P1 polymorphisms and Parkinson's diseaseSamir N Kelada
Department of Environmental Health, Box 357234, University of Washington, Seattle 98195 7234, USA
Neurosci Lett 337:5-8. 2003..Taken together, these results suggest a potentially minor role of GSTP1 in PD, but do not give evidence for associations with either GSTM1 or GSTT1... - The frequency of carpal tunnel syndrome in computer users at a medical facilityGary M Franklin
Neurology 58:1314; author reply 1314-5. 2002 - Environmental risk factors in multiple sclerosis: causes, triggers, and patient autonomyGary M Franklin
Neurology 61:1032-4. 2003
Research Grants
- Disability Risk in Work-Related Musculoskeletal InjuryGary Franklin; Fiscal Year: 2005....