Research Topics
Species | Daniel N FrankSummaryAffiliation: University of Colorado Country: USA Publications
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Detail Information
Publications
Disease phenotype and genotype are associated with shifts in intestinal-associated microbiota in inflammatory bowel diseasesDaniel N Frank
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, Colorado 80045, USA
Inflamm Bowel Dis 17:179-84. 2011..We hypothesize that NOD2 and ATG16L1 risk alleles may be associated with these alterations...
XplorSeq: a software environment for integrated management and phylogenetic analysis of metagenomic sequence dataDaniel N Frank
Department of Molecular, Cellular, and Developmental Biology, Mucosal and Vaccine Research Program Colorado, University of Colorado, Boulder, CO, USA 80309, USA
BMC Bioinformatics 9:420. 2008..As the scale of rDNA-based studies of microbial ecology has expanded, need has arisen for software that is capable of managing, annotating, and analyzing the plethora of diverse data accumulated in these projects...
BARCRAWL and BARTAB: software tools for the design and implementation of barcoded primers for highly multiplexed DNA sequencingDaniel N Frank
Department of Molecular, University of Colorado, Boulder, CO 80309, USA
BMC Bioinformatics 10:362. 2009....
The human nasal microbiota and Staphylococcus aureus carriageDaniel N Frank
Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, Colorado, United States of America
PLoS ONE 5:e10598. 2010..aureus colonization we determined the composition and dynamics of the nasal microbiota and correlated specific microorganisms with S. aureus colonization...
Culture-independent microbiological analysis of foley urinary catheter biofilmsDaniel N Frank
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO, USA
PLoS ONE 4:e7811. 2009..Prevention of catheter-associated urinary tract infection (CAUTI), a leading cause of nosocomial disease, is complicated by the propensity of bacteria to form biofilms on indwelling medical devices [1,2,3,4,5]...
Opportunistic pathogens enriched in showerhead biofilmsLeah M Feazel
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
Proc Natl Acad Sci U S A 106:16393-9. 2009..The health risk associated with showerhead microbiota needs investigation in persons with compromised immune or pulmonary systems...
Culture-independent analysis of aerosol microbiology in a metropolitan subway systemCharles E Robertson
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado, USA
Appl Environ Microbiol 79:3485-93. 2013....
Microbial diversity in chronic open woundsDaniel N Frank
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, USA
Wound Repair Regen 17:163-72. 2009....
Gastrointestinal microbiology enters the metagenomics eraDaniel N Frank
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado 80309 0347, USA
Curr Opin Gastroenterol 24:4-10. 2008..This review summarizes the molecular methods of culture-independent microbiology ('metagenomics') and their recent application to studies of the human gastrointestinal tract in both health and disease...
Identifying genomic and metabolic features that can underlie early successional and opportunistic lifestyles of human gut symbiontsCatherine Lozupone
Department of Chemistry and Biochemistry and Biofrontiers Institute, University of Colorado, Boulder, Colorado 80309, USA
Genome Res 22:1974-84. 2012....
Altered vaginal microbiota are associated with perinatal mother-to-child transmission of HIV in African women from Burkina FasoDaniel N Frank
Department of Medicine, Division of Infectious Diseases, University of Colorado School of Medicine, Denver, CO, USA
J Acquir Immune Defic Syndr 60:299-306. 2012..Because perturbations in vaginal microbial communities are associated with sexual transmission of HIV, we determined whether perinatal MTCT is associated with the vaginal microbiotas of HIV-infected mothers...
Investigating the biological and clinical significance of human dysbiosesDaniel N Frank
Division of Infectious Diseases, School of Medicine, University of Colorado, School of Medicine, Aurora, CO 80045, USA
Trends Microbiol 19:427-34. 2011..g. host single nucleotide polymorphisms and host gene expression) and for integrating patient-based data with results from experimental animal models to gain deeper understanding of how host-microbe interactions impact disease...
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseasesDaniel N Frank
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309 0347, USA
Proc Natl Acad Sci U S A 104:13780-5. 2007..Patient stratification by GI microbiota provides further evidence that CD represents a spectrum of disease states and suggests that treatment of some forms of IBD may be facilitated by redress of the detected microbiological imbalances...
Eucaryotic diversity in a hypersaline microbial matLeah M Feazel
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 90309 0347, USA
Appl Environ Microbiol 74:329-32. 2008..Six eucaryotic kingdoms were represented, as well as a novel cluster of sequences. Nematode sequences dominated the clone libraries...
Prevalence and abundance of Staphylococcus aureus in the middle meatus of patients with chronic rhinosinusitis, nasal polyps, and asthmaVijay R Ramakrishnan
Department of Otolaryngology Head and Neck Surgery, University of Colorado, Aurora, CO
Int Forum Allergy Rhinol 3:267-71. 2013..Staphylococcus aureus (SA) appears to be implicated in a number of infectious and inflammatory mechanisms, and may be particularly relevant in CRS patients with nasal polyps and asthma...
Pathogen-specific antibodies: codependent no longerEdward N Janoff
Mucosal and Vaccine Research Program Colorado, University of Colorado Denver, RC 2, Box B 168, 12700 E 19th Ave, Aurora, CO 80045, USA
J Clin Invest 120:1039-42. 2010..These data suggest that pathogens have the capacity to generate broad metabolic responses as a result of surface binding by pathogen-specific antibodies, effects that may hold therapeutic promise...
