Matthew B Francis
Affiliation: University of California
- Finbloom J, Slack C, Bruns C, Jeong K, Wemmer D, Pines A, et al. Rotaxane-mediated suppression and activation of cucurbituril for molecular detection by (129)Xe hyperCEST NMR. Chem Commun (Camb). 2016;52:3119-22 pubmed publisher..This contrast-upon-activation (129)Xe NMR platform allows for modular synthesis and can be expanded to applications in detection and disease imaging. ..
- Rosen C, Kwant R, MacDonald J, Rao M, Francis M. Capture and Recycling of Sortase?A through Site-Specific Labeling with Lithocholic Acid. Angew Chem Int Ed Engl. 2016;55:8585-9 pubmed publisher..Capture and recycling of the LA-Pro-SrtA?7M conjugate was achieved using ?CD-modified sepharose resin. The LA-Pro-SrtA?7M conjugate retained full enzymatic activity, even after multiple rounds of recycling. ..
- Sangsuwan R, Obermeyer A, Tachachartvanich P, Palaniappan K, Francis M. Direct detection of nitrotyrosine-containing proteins using an aniline-based oxidative coupling strategy. Chem Commun (Camb). 2016;52:10036-9 pubmed publisher..Following this, an oxidative coupling reaction is used to attach anilines bearing fluorescence reporters or affinity probes. Features of this approach include fast reaction times, pmol-level sensitivity, and excellent chemoselectivity. ..
- Smith M, Francis M. Methods for Generating Microbial Cocultures that Grow in the Absence of Fixed Carbon or Nitrogen. Methods Mol Biol. 2018;1772:45-60 pubmed publisher..The methods we used to develop this coculture are described in detail in the following chapter, including notes detailing some of our additional observations or thoughts on this system. ..