Affiliation: University of California
- Breaching biological barriers: protein translocation domains as tools for molecular imaging and therapyBenjamin L Franc
Department of Radiology, Nuclear Medicine Program, University of California, San Francisco 94143 0252, USA
Mol Imaging 2:313-23. 2003..Here we review several natural and synthetic PTDs that have evolved in the quest for easier translocation across biological barriers and the application of these peptide domains to in vivo delivery of imaging agents...
- Pericardial lymph node involvement in lymphoma as identified on PETBenjamin Franc
Department of Radiology, Division of Nuclear Medicine, Stanford University School of Medicine, Palo Alto, California 94122, USA
Clin Nucl Med 29:741-2. 2004
- The role of a positron- and high-energy gamma photon probe in intraoperative localization of recurrent melanomaBenjamin L Franc
Department of Radiology, University of California San Francisco, San Francisco, CA 94143 0252, USA
Clin Nucl Med 30:787-91. 2005....
- Positron emission tomography, positron emission tomography-computed tomography, and molecular imaging of the breast cancer patientBenjamin L Franc
Department of Radiology, University of California, San Francisco, San Francisco, California 94143 0252, USA
Semin Roentgenol 42:265-79. 2007
- Interpretation, accuracy and management implications of FDG PET/CT in cutaneous malignant melanomaMatthew S Falk
Department of Radiology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0628, USA
Nucl Med Commun 28:273-80. 2007..To investigate the accuracy of different interpretative approaches and to evaluate the management implications of fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in cutaneous malignant melanoma...
- Correcting tumour SUV for enhanced bone marrow uptake: retrospective 18F-FDG PET/CT studiesBoon Keng Teo
Department of Radiology, University of California, San Francisco, USA
Nucl Med Commun 29:359-66. 2008..We tested this hypothesis by quantifying total F-FDG uptake in the bone marrow of patients with visibly enhanced bone marrow uptake and computing its effect on tumour SUV...
- Anterior layering of excreted 18F-FDG in the bladder on PET/CT: frequency and causeDerk D Purcell
Department of Radiology, University of California, San Francisco, Box 0628, M 392, 505 Parnassus Ave, San Francisco, CA 94143 0628, USA
AJR Am J Roentgenol 189:W96-9. 2007..v. iodinated contrast material and is due to displacement of FDG by excreted iodinated contrast material; this phenomenon may unmask FDG-avid bladder disease...
- Role of IV iodinated contrast material in 18F-FDG PET/CT of liver metastasesShiva Badiee
Department of Radiology, University of California, San Francisco, Box 0628, M 372, 505 Parnassus Ave, San Francisco, CA 94143 0628, USA
AJR Am J Roentgenol 191:1436-9. 2008..The purpose of our study was to investigate the role of IV iodinated contrast material in the evaluation of hepatic metastases at (18)F-FDG PET/CT...
- Case 110: Nonossifying fibromaSteven W Hetts
Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
Radiology 243:288-92. 2007
- Phase I dose escalation of iodine-131-metaiodobenzylguanidine with myeloablative chemotherapy and autologous stem-cell transplantation in refractory neuroblastoma: a new approaches to Neuroblastoma Therapy Consortium StudyKatherine K Matthay
Department of Pediatrics, University of California, San Francisco, School of Medicine, and UCSF Children s Hospital, San Francisco, CA 94143 0106, USA
J Clin Oncol 24:500-6. 2006..To determine the maximum-tolerated dose (MTD) and toxicity of iodine-131-metaiodobenzylguanidine ((131)I-MIBG) with carboplatin, etoposide, melphalan (CEM) and autologous stem-cell transplantation (ASCT) in refractory neuroblastoma...
- Can positron emission tomography (PET) or PET/Computed Tomography (CT) acquired in a nontreatment position be accurately registered to a head-and-neck radiotherapy planning CT?Andrew B Hwang
Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, USA
Int J Radiat Oncol Biol Phys 73:578-84. 2009....
- Rodent brain imaging with SPECT/CTYoungho Seo
Department of Radiology, University of California, San Francisco, California 94143, USA
Med Phys 34:1217-20. 2007..We have demonstrated a capability of imaging regions of cerebral blood flow deficit in MCAO rat brains in vivo using a pinhole SPECT dedicated to small animal imaging...
- Partial-volume correction in PET: validation of an iterative postreconstruction method with phantom and patient dataBoon Keng Teo
Department of Radiology, University of California, San Francisco, San Francisco, CA 94107, USA
J Nucl Med 48:802-10. 2007..An iterative postreconstruction method was evaluated that corrects for PVEs without a priori knowledge of tumor size or background...
- Iodine-131--metaiodobenzylguanidine double infusion with autologous stem-cell rescue for neuroblastoma: a new approaches to neuroblastoma therapy phase I studyKatherine K Matthay
Department of Pediatrics, University of California, San Francisco, 505 Parnassus, M647, San Francisco, CA 94143 0106, USA
J Clin Oncol 27:1020-5. 2009..The goal was to determine the maximum-tolerated dose of (131)I-MIBG in two consecutive infusions at a 2-week interval, supported by autologous stem-cell rescue (ASCR) 2 weeks after the second dose...
- Tumor fluoro-2-deoxy-D-glucose avidity on positron emission tomographic scan predicts mortality in patients with early-stage pure and mixed bronchioloalveolar carcinomaDan J Raz
Department of Surgery, University of California, San Francisco, San Francisco, Calif 94131, USA
J Thorac Cardiovasc Surg 132:1189-95. 2006..We investigated whether tumor FDG avidity was associated with worse survival among patients with completely resected node-negative pure and mixed bronchioloalveolar carcinoma...
- Progress in SPECT/CT imaging of prostate cancerYoungho Seo
Department of Radiology, University of California, San Francisco, California, USA
Technol Cancer Res Treat 5:329-36. 2006..There were also changes in interpretations for 4 of 12 studies although the changes were not sufficient to alter prognosis or the patient treatment plan...
- Correction of photon attenuation and collimator response for a body-contouring SPECT/CT imaging systemYoungho Seo
Department of Radiology, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107 1739, USA
J Nucl Med 46:868-77. 2005..In this article, we evaluate a novel iterative reconstruction algorithm using the SPECT/CT data obtained from phantoms and (111)In-capromab pendetide patient studies...
- Lymphatic drainage patterns of head and neck cutaneous melanoma observed on lymphoscintigraphy and sentinel lymph node biopsyDoris Lin
Department of Otolaryngology Head and Neck Surgery, University of California, San Francisco, 2380 Sutter Street, Box 1703, San Francisco, CA 94143 0342, USA
Head Neck 28:249-55. 2006....
- Evaluation of semi-quantitative scoring system for metaiodobenzylguanidine (mIBG) scans in patients with relapsed neuroblastomaJulia A Messina
Department of Pediatrics, University of California, San Francisco, California 94143, USA
Pediatr Blood Cancer 47:865-74. 2006..The purpose of this study was to determine the accuracy of two semi-quantitative scoring systems to assess response to (131)I-metaiodobenzylguanidine (mIBG) therapy in recurrent neuroblastoma...
- Biodistributions of 177Lu- and 111In-labeled 7E11 antibodies to prostate-specific membrane antigen in xenograft model of prostate cancer and potential use of 111In-7E11 as a pre-therapeutic agent for 177Lu-7E11 radioimmunotherapyMei Hsiu Pan
Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
Mol Imaging Biol 11:159-66. 2009..To serve as a radioimmunotherapeutic agent, a kinetically inert conjugate is desired to maximize tumor uptake and tumor radiation dose with minimal nonspecific exposure to bone marrow and other major organs...
- Diagnostic value of PET/CT for the staging and restaging of pediatric tumorsMargit Kleis
Department of Radiology, University of California, 505 Parnassus Avenue, San Francisco, CA 94143 0628, USA
Eur J Nucl Med Mol Imaging 36:23-36. 2009....
- Low uptake of Tc-99m tetrofosmin in lung cancer: a case reportBenjamin Franc
Department of Radiology, Division of Nuclear Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 943905 5281, USA
Clin Nucl Med 27:698-700. 2002..A brief review of the literature is provided and possible explanations for this difference in tracer uptake are discussed...
- Small-animal SPECT and SPECT/CT: important tools for preclinical investigationBenjamin L Franc
Department of Radiology, Center for Molecular and Functional Imaging, University of California, San Francisco, California, USA
J Nucl Med 49:1651-63. 2008....
- Development of an optimized activatable MMP-14 targeted SPECT imaging probeGregory A Watkins
Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, 185 Berry Street, Suite 350, Box 0946, San Francisco, CA 94107, United States
Bioorg Med Chem 17:653-9. 2009..The combination of computational chemistry, parallel synthesis and biochemical screening, therefore, shows promise as a set of tools for developing new radiolabeled probes that are sensitive to protease activity...
- Assessment of the sources of error affecting the quantitative accuracy of SPECT imaging in small animalsAndrew B Hwang
Joint Graduate Group in Bioengineering, University of California San Francisco and University of California Berkeley, CA, USA
Phys Med Biol 53:2233-52. 2008..e. modeling the finite collimator spatial resolution in iterative reconstruction algorithms) can significantly reduce the partial volume errors...
- FDG PET imaging in the evaluation of post-transplant lymphoproliferative disorder following renal transplantationAngus R O'Conner
Department of Radiology, Nottingham City Hospital, UK
Nucl Med Commun 26:1107-11. 2005..To assess the usefulness of fluorodeoxyglucose positron emission tomography (FDG PET) in the evaluation of post-transplant lymphoproliferative disorder (PTLD) following renal transplantation...
- Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activationElena A Goun
Department of Chemistry, Stanford University, Stanford, California 94305, USA
Bioconjug Chem 17:787-96. 2006..These APTD peptide-based molecules may facilitate targeted delivery of therapeutics or imaging agents to PSA-expressing prostate cancers...
- Apoptosis in a rodent model of cranial suture fusion: in situ imaging and gene expression analysisKenton D Fong
Department of Surgery, Division of Plastic and Reconstructive Surgery, Stanford University, Calif 94305 5148, USA
Plast Reconstr Surg 113:2037-47. 2004..These data suggest that although overall apoptotic activity in rat patent and fusing sutures is similar, the pathways mediating apoptosis within each suture are distinct...
- Novel Cancer Targeting Mechanism for Nuclear ImagingBenjamin Franc; Fiscal Year: 2006..In summary, the targeting strategy developed in this project aims to open the door to novel cancer targets for nuclear imaging. ..