M D Frame

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi request reprint Increased flow precedes remote arteriolar dilations for some microapplied agonists
    M D Frame
    Department of Anesthesiology, Biomedical Engineering Program, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Am J Physiol Heart Circ Physiol 278:H1186-95. 2000
  2. ncbi request reprint Localized adenovirus-mediated gene transfer into vascular smooth muscle in the hamster cheek pouch
    M D Frame
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Microcirculation 8:403-13. 2001
  3. ncbi request reprint Diminished arteriolar responses in nitrate tolerance involve ROS and angiotensin II
    Mary D Frame
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Am J Physiol Heart Circ Physiol 282:H2377-85. 2002
  4. ncbi request reprint Network vascular communication initiated by increases in tissue adenosine
    R J Rivers
    Department of Anesthesiology, Biomedical Engineering Program, University of Rochester, Rochester, NY, USA
    J Vasc Res 36:193-200. 1999
  5. ncbi request reprint Flow-induced cytoskeletal changes in endothelial cells growing on curved surfaces
    M D Frame
    Department of Anesthesiology, University of Rochester, NY 14642, USA Molly
    Microcirculation 7:419-27. 2000
  6. ncbi request reprint Shear stress gradient over endothelial cells in a curved microchannel system
    M D Frame
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Biorheology 35:245-61. 1998
  7. ncbi request reprint Technique for using video microscopy and indicator dilution for repeated measurements of cardiac output in small animals
    R J Rivers
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, New York 14642, USA
    Anesthesiology 94:489-95. 2001
  8. ncbi request reprint Mechanisms initiating integrin-stimulated flow recruitment in arteriolar networks
    Mary D Frame
    Department of Biomedical Engineering, Stony Brook University, HSC T18 030, Stony Brook, NY 11794 8181, USA
    J Appl Physiol 102:2279-87. 2007
  9. ncbi request reprint Initiation of remote microvascular preconditioning requires K(ATP) channel activity
    Lauren Mabanta
    Dept of Biomedical Engineering, SUNY Stony Brook, Stony Brook, New York 11794, USA
    Am J Physiol Heart Circ Physiol 290:H264-71. 2006
  10. ncbi request reprint Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase
    Zheng Gen Jin
    Center for Cardiovascular Research and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circ Res 93:354-63. 2003

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Increased flow precedes remote arteriolar dilations for some microapplied agonists
    M D Frame
    Department of Anesthesiology, Biomedical Engineering Program, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Am J Physiol Heart Circ Physiol 278:H1186-95. 2000
    ..Papaverine had no remote effects. This study suggests that, although remote responses to some agonists are induced by primary signals to dilate, additionally, network changes in flow can stimulate extensive remote changes in diameter...
  2. ncbi request reprint Localized adenovirus-mediated gene transfer into vascular smooth muscle in the hamster cheek pouch
    M D Frame
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Microcirculation 8:403-13. 2001
    ..Our purpose was to develop a method for adenovirus delivery to the hamster cheek pouch to experimentally target gene transfer in tissue used for microvascular studies...
  3. ncbi request reprint Diminished arteriolar responses in nitrate tolerance involve ROS and angiotensin II
    Mary D Frame
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    Am J Physiol Heart Circ Physiol 282:H2377-85. 2002
    ..In summary, terminal arterioles are affected by nitrates to a greater extent than the arcade arterioles that feed them, in a process dependent on angiotensin II and ROS...
  4. ncbi request reprint Network vascular communication initiated by increases in tissue adenosine
    R J Rivers
    Department of Anesthesiology, Biomedical Engineering Program, University of Rochester, Rochester, NY, USA
    J Vasc Res 36:193-200. 1999
    ..Thus, increases in tissue adenosine may be critical for vascular communication of metabolic demands without regard to the specific blood flow path...
  5. ncbi request reprint Flow-induced cytoskeletal changes in endothelial cells growing on curved surfaces
    M D Frame
    Department of Anesthesiology, University of Rochester, NY 14642, USA Molly
    Microcirculation 7:419-27. 2000
    ..Our purpose was to investigate the effect of the shape of the growth surface (curved versus flat) on flow-induced F-actin organization in endothelial cells...
  6. ncbi request reprint Shear stress gradient over endothelial cells in a curved microchannel system
    M D Frame
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
    Biorheology 35:245-61. 1998
    ..The wall shear stress gradient over the nucleus was 2-fold greater in the radial versus axial directions, and was sensitive to lateral versus midline positioned nuclei...
  7. ncbi request reprint Technique for using video microscopy and indicator dilution for repeated measurements of cardiac output in small animals
    R J Rivers
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, New York 14642, USA
    Anesthesiology 94:489-95. 2001
    ..2 +/- 0.5 ml/100 g body weight, within the normal range for hamsters. CONCLUSIONS: Fluorescent dye dilution and video microscopy can be used to repeatedly determine cardiac output or blood volume in small animals...
  8. ncbi request reprint Mechanisms initiating integrin-stimulated flow recruitment in arteriolar networks
    Mary D Frame
    Department of Biomedical Engineering, Stony Brook University, HSC T18 030, Stony Brook, NY 11794 8181, USA
    J Appl Physiol 102:2279-87. 2007
    ....
  9. ncbi request reprint Initiation of remote microvascular preconditioning requires K(ATP) channel activity
    Lauren Mabanta
    Dept of Biomedical Engineering, SUNY Stony Brook, Stony Brook, New York 11794, USA
    Am J Physiol Heart Circ Physiol 290:H264-71. 2006
    ..RMP was blocked during SNP, but not during DZ, stimulation. Thus stimulation of the RMP response requires mitochondrial K(ATP) channel activity after stimulation by nitric oxide donors...
  10. ncbi request reprint Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase
    Zheng Gen Jin
    Center for Cardiovascular Research and Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Circ Res 93:354-63. 2003
    ..Finally, we show that inhibiting VEGFR2 kinase significantly reduces flow-mediated NO-dependent arteriolar dilation in vivo. These data identify VEGFR2 as a key mechanotransducer that activates eNOS in response to blood flow...
  11. ncbi request reprint Arteriolar flow recruitment with vitronectin receptor stimulation linked to remote wall shear stress
    Randall J Fox
    Department of Anesthesiology, Center for Cardiovascular Research, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA
    Microvasc Res 64:414-24. 2002
    ..In contrast, NO alone initiates flow recruitment to the entire network, along multiple parallel flow paths...
  12. ncbi request reprint Regulation of flow and wall shear stress in arteriolar networks of the hamster cheek pouch
    Randall J Fox
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Appl Physiol 92:2080-8. 2002
    ..With SNP, diameter change correlated with the baseline (before SNP) shear stress conditions...
  13. ncbi request reprint Remote microvascular preconditioning alters specific vasoactive responses
    Mary D Frame
    Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794 8181, USA
    Microcirculation 14:739-51. 2007
    ..The goal of this study was to further characterize RMP and to investigate the extent to which RMP altered local vasoactive responses...