B Foxman

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. doi request reprint Impact of technical sources of variation on the hand microbiome dynamics of healthcare workers
    Mariana Rosenthal
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 9:e88999. 2014
  2. pmc Conceptualizing human microbiota: from multicelled organ to ecological community
    Betsy Foxman
    Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA
    Interdiscip Perspect Infect Dis 2008:613979. 2008
  3. doi request reprint Urinary tract infection syndromes: occurrence, recurrence, bacteriology, risk factors, and disease burden
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109 2029, USA Electronic address
    Infect Dis Clin North Am 28:1-13. 2014
  4. doi request reprint Exploring the effect of dentition, dental decay and familiality on oral health using metabolomics
    Betsy Foxman
    Department of Epidemiology, University of Michigan, United States Electronic address
    Infect Genet Evol 22:201-7. 2014
  5. ncbi request reprint Mycoplasma, bacterial vaginosis-associated bacteria BVAB3, race, and risk of preterm birth in a high-risk cohort
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI Electronic address
    Am J Obstet Gynecol 210:226.e1-7. 2014
  6. pmc Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital
    Jonas Marschall
    Division of Infectious Diseases, Washington University School of Medicine, St, Louis, MO 63110, USA
    BMC Infect Dis 13:213. 2013
  7. pmc Alternative approaches to conventional treatment of acute uncomplicated urinary tract infection in women
    Betsy Foxman
    Center for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, 48109 2029, USA
    Curr Infect Dis Rep 15:124-9. 2013
  8. pmc Implications of the human microbiome project for epidemiology
    Betsy Foxman
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Am J Epidemiol 177:197-201. 2013
  9. pmc Early development of bacterial community diversity in emergently placed urinary catheters
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109 2029, USA
    BMC Res Notes 5:332. 2012
  10. pmc Library on a slide for bacterial comparative genomics
    Lixin Zhang
    Department of Epidemiology, University of Michigan School of Public Health, 109 Observatory Street, Ann Arbor, MI48109, USA
    BMC Microbiol 4:12. 2004

Collaborators

Detail Information

Publications117 found, 100 shown here

  1. doi request reprint Impact of technical sources of variation on the hand microbiome dynamics of healthcare workers
    Mariana Rosenthal
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 9:e88999. 2014
    ..Glove-juice sample collection may likely be the method of choice in hand hygiene studies in the healthcare setting. ..
  2. pmc Conceptualizing human microbiota: from multicelled organ to ecological community
    Betsy Foxman
    Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA
    Interdiscip Perspect Infect Dis 2008:613979. 2008
    ..Each conceptualization leads to different predictions, methodologies, and research strategies...
  3. doi request reprint Urinary tract infection syndromes: occurrence, recurrence, bacteriology, risk factors, and disease burden
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109 2029, USA Electronic address
    Infect Dis Clin North Am 28:1-13. 2014
    ..9% of all ambulatory visits in the United States. This review defines the major UTI syndromes, their occurrence and recurrence, bacteriology, risk factors, and disease burden. ..
  4. doi request reprint Exploring the effect of dentition, dental decay and familiality on oral health using metabolomics
    Betsy Foxman
    Department of Epidemiology, University of Michigan, United States Electronic address
    Infect Genet Evol 22:201-7. 2014
    ....
  5. ncbi request reprint Mycoplasma, bacterial vaginosis-associated bacteria BVAB3, race, and risk of preterm birth in a high-risk cohort
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI Electronic address
    Am J Obstet Gynecol 210:226.e1-7. 2014
    ..We sought to assess the relationship between preterm birth and selected vaginal bacterial taxa associated with preterm birth either directly or through their association with bacterial vaginosis (BV)...
  6. pmc Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital
    Jonas Marschall
    Division of Infectious Diseases, Washington University School of Medicine, St, Louis, MO 63110, USA
    BMC Infect Dis 13:213. 2013
    ..Asymptomatic bacteriuria (ASB) is frequently treated with antibiotics without a clear indication. Our goal was to determine patient and pathogen factors suggestive of ASB...
  7. pmc Alternative approaches to conventional treatment of acute uncomplicated urinary tract infection in women
    Betsy Foxman
    Center for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, 48109 2029, USA
    Curr Infect Dis Rep 15:124-9. 2013
    ..We review the recent literature regarding the effects of functional food products, probiotics, vaccines, and alternative treatments on treating and preventing UTI...
  8. pmc Implications of the human microbiome project for epidemiology
    Betsy Foxman
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Am J Epidemiol 177:197-201. 2013
    ....
  9. pmc Early development of bacterial community diversity in emergently placed urinary catheters
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109 2029, USA
    BMC Res Notes 5:332. 2012
    ..However, the natural history of the biofilms that rapidly form on urinary catheters and lead to infection is not well described...
  10. pmc Library on a slide for bacterial comparative genomics
    Lixin Zhang
    Department of Epidemiology, University of Michigan School of Public Health, 109 Observatory Street, Ann Arbor, MI48109, USA
    BMC Microbiol 4:12. 2004
    ....
  11. pmc Frequency of antimicrobial resistance among invasive and colonizing Group B streptococcal isolates
    Stephanie M Borchardt
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA
    BMC Infect Dis 6:57. 2006
    ..We describe the age-specific antibiotic susceptibility profile and capsular type distribution among invasive and colonizing GBS strains...
  12. pmc Prevalence and risk factors for vaginal Candida colonization in women with type 1 and type 2 diabetes
    Ella M de Leon
    Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
    BMC Infect Dis 2:1. 2002
    ..Diabetes mellitus increases the rate of vaginal colonization and infection with Candida species..
  13. pmc The frequency of genes encoding three putative group B streptococcal virulence factors among invasive and colonizing isolates
    Shannon D Manning
    National Food Safety and Toxicology Center and Department of Pediatrics and Human Development, Michigan State University, East Lansing, Michigan, USA
    BMC Infect Dis 6:116. 2006
    ..It is not known, however, whether these genes occur more frequently in invasive versus colonizing GBS strains...
  14. ncbi request reprint Acute pyelonephritis in US hospitals in 1997: hospitalization and in-hospital mortality
    Betsy Foxman
    University of Michigan, School of Public Health, Department of Epidemiology, 109 Observatory Street, Ann Arbor 48109 2029, USA
    Ann Epidemiol 13:144-50. 2003
    ..To describe the 1997 incidence of hospitalization for acute pyelonephritis in the US and the risk factors for in-hospital mortality associated with acute pyelonephritis...
  15. ncbi request reprint Challenges of epidemiology in the 21st century: comments from the leaders of several epidemiology associations
    Betsy Foxman
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Ann Epidemiol 15:1-4. 2005
    ..Increased communication between all epidemiologists--regardless of specialty--is an excellent first step toward developing strategies to meet these challenges...
  16. doi request reprint Acquisition and transmission of group B Streptococcus during pregnancy
    Betsy Foxman
    Center for Molecular and Clinical Epidemiology, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
    J Infect Dis 198:1375-8. 2008
    ....
  17. ncbi request reprint Measures of sexual partnerships: lengths, gaps, overlaps, and sexually transmitted infection
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109 2029, USA
    Sex Transm Dis 33:209-14. 2006
    ..We describe the distributions of gaps, lengths, and overlaps among participants in a random-digit dialing survey conducted among 1194 Seattle residents during 2003-2004...
  18. ncbi request reprint Common use in the general population of sexual enrichment AIDS and drugs to enhance sexual experience
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, 48109 2029, USA
    Sex Transm Dis 33:156-62. 2006
    ..We describe the prevalence of ever and current use of sexual enrichment aids and of using drugs to enhance the sexual experience, and correlates of that usage...
  19. ncbi request reprint Epidemiology of urinary tract infections: transmission and risk factors, incidence, and costs
    Betsy Foxman
    Department of Epidemiology, Center for Molecular and Clinical Epidemiology of Infectious Diseases, University of Michigan School of Public Health, 109 Observatory Street, Ann Arbor, MI 48109 2029, USA
    Infect Dis Clin North Am 17:227-41. 2003
    ..The benefits of successfully preventing UTI are substantial...
  20. ncbi request reprint Contributions of molecular epidemiology to the understanding of infectious disease transmission, pathogenesis, and evolution
    Betsy Foxman
    Center for Molecular and Clinical Epidemiology of Infectious Diseases, Department of Epidemiology, University of Michigan School of Public Health, 109 Observatory Street, Ann Arbor, MI 48109, USA
    Ann Epidemiol 17:148-56. 2007
    ..Describe the contributions of molecular genetics to our understanding of the molecular epidemiology of infectious diseases caused by bacteria...
  21. pmc Risk factors for group B streptococcal colonization: potential for different transmission systems by capsular type
    B Foxman
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
    Ann Epidemiol 17:854-62. 2007
    ..Food-borne transmission is also possible, as GBS is a known fish and bovine pathogen. We conducted a prospective cohort study in order to identify risk factors for acquisition...
  22. ncbi request reprint Incidence and duration of group B Streptococcus by serotype among male and female college students living in a single dormitory
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, 109 South Observatory Street, Ann Arbor, MI 48109, USA
    Am J Epidemiol 163:544-51. 2006
    ..001). Based on the overall incidence, transmission occurred between roommate pairs at the rate expected. Group B Streptococcus colonization is frequent and dynamic, but it is not transmitted by casual contact...
  23. ncbi request reprint Molecular epidemiology: focus on infection
    B Foxman
    Department of Epidemiology and Center for Molecular and Clinical Epidemiology of Infectious Diseases, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Am J Epidemiol 153:1135-41. 2001
    ..They close with some thoughts about training future epidemiologists to best take advantage of the new opportunities that arise from integrating epidemiologic methods with modern molecular biology...
  24. ncbi request reprint Urinary tract infection among women aged 40 to 65: behavioral and sexual risk factors
    B Foxman
    Department of Epidemiology, University of Michigan School of Public Health, 109 Observatory St, Ann Arbor, MI 48109, USA
    J Clin Epidemiol 54:710-8. 2001
    ..Risk factors for UTI among women 40-65 differ from those for younger women and these differences cannot be attributed solely to changes in menopausal status...
  25. ncbi request reprint Lactation mastitis: occurrence and medical management among 946 breastfeeding women in the United States
    Betsy Foxman
    Department of Epidemiology and Center for Molecular and Clinical Epidemiology of Infectious Diseases, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
    Am J Epidemiol 155:103-14. 2002
    ..6, 95% CI: 0.41, 1.01; < or =6 times: OR = 0.4, 95% CI: 0.19, 0.82). Duration of feeding was not associated with mastitis risk...
  26. ncbi request reprint Uropathogenic Escherichia coli are more likely than commensal E. coli to be shared between heterosexual sex partners
    Betsy Foxman
    Center for Molecular and Clinical Epidemiology, Department of Epidemiology, The University of Michigan School of Public Health, Ann Arbor 48109, USA
    Am J Epidemiol 156:1133-40. 2002
    ..09, 95% CI: 1.09, 4.00). Uropathogenic E. coli are more likely than commensal E. coli to be shared with a current heterosexual sex partner. Both sexual behaviors and a bacterial virulence factor, P pili, modified sharing...
  27. ncbi request reprint Risk factors for second urinary tract infection among college women
    B Foxman
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, USA
    Am J Epidemiol 151:1194-205. 2000
    ..Although the risk of second UTI is strongly influenced by sexual behavior, women with a first UTI caused by E. coli are more likely than are those with a non-E. coli first UTI to have a second UTI within 6 months...
  28. doi request reprint The epidemiology of urinary tract infection
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA
    Nat Rev Urol 7:653-60. 2010
    ..As uropathogens are increasingly becoming resistant to currently available antibiotics, it may be time to explore alternative strategies for managing UTI...
  29. ncbi request reprint Candida vaginitis: self-reported incidence and associated costs
    B Foxman
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor 48109 2029, USA
    Sex Transm Dis 27:230-5. 2000
    ..Incidence of Candida vaginitis by age and racial or ethnic group is poorly described...
  30. pmc Association between Mycobacterium tuberculosis Beijing/W lineage strain infection and extrathoracic tuberculosis: Insights from epidemiologic and clinical characterization of the three principal genetic groups of M. tuberculosis clinical isolates
    Y Kong
    Epidemiology Department, School of Public Health, University of Michigan, 109 S Observatory Street, Ann Arbor, MI 48109 2029, USA
    J Clin Microbiol 45:409-14. 2007
    ..85 [1.33, 6.12]). Thus, the Beijing/W lineage strains may have some special biological features that facilitate the development of extrathoracic tuberculosis...
  31. pmc Population-based study of deletions in five different genomic regions of Mycobacterium tuberculosis and possible clinical relevance of the deletions
    Y Kong
    Epidemiology Department, School of Public Health, University of Michigan, 109 S Observatory Street, Ann Arbor, MI 48109 2029, USA
    J Clin Microbiol 44:3940-6. 2006
    ..These two combinations of RD deletions have the potential for predicting the clinical presentation of M. tuberculosis infection in the human host...
  32. pmc Streptococcus agalactiae pulsed-field gel electrophoresis patterns cross capsular types
    P Pillai
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
    Epidemiol Infect 137:1420-5. 2009
    ..Although PFGE types appear to be a valid surrogate for capsular typing of isolates from the same individual, it is not a valid surrogate for serotype in isolates from different individuals...
  33. ncbi request reprint Diversity and sharing of Haemophilus influenzae strains colonizing healthy children attending day-care centers
    Rand S Farjo
    Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109 0244, USA
    Pediatr Infect Dis J 23:41-6. 2004
    ..This study describes the prevalence rates of H. influenzae colonization in a large number of children attending day-care centers and examines the genetic diversity of colonizing strains and the degree of sharing among children...
  34. pmc Integrated genomic map from uropathogenic Escherichia coli J96
    L J Melkerson-Watson
    Department of Pediatrics, School of Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
    Infect Immun 68:5933-42. 2000
    ..The insertional strains generated in construction of the integrated genomic map provide useful physical and genetic markers for further characterization of the J96 genome...
  35. ncbi request reprint Widespread distribution of urinary tract infections caused by a multidrug-resistant Escherichia coli clonal group
    A R Manges
    Division of Epidemiology and Public Health Biology, School of Public Health, University of California at Berkeley, 94720, USA
    N Engl J Med 345:1007-13. 2001
    ..coli strains with resistance to trimethoprim-sulfamethoxazole. The widespread distribution and high prevalence of E. coli clonal group A has major public health implications...
  36. pmc Probe hybridization array typing: a binary typing method for Escherichia coli
    U Srinivasan
    Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor, MI 48109, USA
    J Clin Microbiol 45:206-14. 2007
    ..e., "library on a slide"), the discriminatory ability can be varied based on the probe set, and PHAT is readily adapted to other bacterial species with high variation in genetic content...
  37. pmc Comparative whole-genome analysis of Streptococcus mutans isolates within and among individuals of different caries status
    L Zhang
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
    Oral Microbiol Immunol 24:197-203. 2009
    ..Genotypic analyses of Streptococcus mutans using fingerprinting methods depend on a few genetic loci being different but do not reveal the underlying genome-wide differences between strains...
  38. ncbi request reprint Molecular epidemiology of 3 putative virulence genes for Escherichia coli urinary tract infection-usp, iha, and iroN(E. coli)
    Richard J Bauer
    Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor, MI 48109, USA
    J Infect Dis 185:1521-4. 2002
    ..6x10-9), in periurethral isolates (P=.001), and in isolates from patients with UTI who were aged 40-65 years (P=.004), when compared with the rectal isolates; iha was not associated with UTI in this study...
  39. ncbi request reprint Optimization of a fluorescent-based phosphor imaging dot blot DNA hybridization assay to assess E. coli virulence gene profiles
    L Zhang
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA
    J Microbiol Methods 44:225-33. 2001
    ..Using the X-ray film signal detection procedure with Southern confirmation as a gold standard, we obtained a sensitivity and specificity of 87-99% for a rule requiring no retesting for all but one gene probe...
  40. ncbi request reprint Prevalence of group B streptococcus colonization and potential for transmission by casual contact in healthy young men and women
    Shannon D Manning
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, USA
    Clin Infect Dis 39:380-8. 2004
    ..Large prospective studies are needed to better understand colonization site-specific factors for GBS and to clarify potential transmission modes...
  41. ncbi request reprint Frequency of antibiotic resistance among group B Streptococcus isolated from healthy college students
    S D Manning
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
    Clin Infect Dis 33:E137-9. 2001
    ..Observed resistance rates were twice as high as those reported among pregnant women from the same geographic area 2 years prior...
  42. pmc Caries resistance as a function of age in an initially caries-free population
    A Wen
    Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109, USA
    J Dent Res 91:671-5. 2012
    ..For children between 1 and 18 years of age, there was not a "threshold age" after which a caries-free child's risk of caries onset is significantly reduced...
  43. pmc Molecular epidemiologic identification of Escherichia coli genes that are potentially involved in movement of the organism from the intestinal tract to the vagina and bladder
    Jingping Xie
    Department of Epidemiology, University of Michigan School of Public Health, 109 Observatory Street, Ann Arbor, MI 48109 2029, USA
    J Clin Microbiol 44:2434-41. 2006
    ..Twelve genetic regions occurred more often in multisite isolates than in rectal site-only isolates. Eleven of these 12 genetic regions are homologous to regions in the sequenced uropathogenic E. coli CFT073 strain...
  44. pmc Long-term Escherichia coli asymptomatic bacteriuria among women with diabetes mellitus
    Shona Dalal
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA
    Clin Infect Dis 49:491-7. 2009
    ..We estimated the duration of colonization and the rate of recolonization among successively isolated E. coli from diabetic women with ASB and compared the virulence profiles with uropathogenic and commensal E. coli...
  45. pmc Prevalence of known P-fimbrial G alleles in Escherichia coli and identification of a new adhesin class
    S D Manning
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
    Clin Diagn Lab Immunol 8:637-40. 2001
    ..The novel adhesin gene has 65% identity to the class I adhesin gene, 44% identity to the class II adhesin gene, and 43% identity to the class III adhesin gene...
  46. doi request reprint Sexual networks are diverse and complex: prevalence of relationships bridging population subgroups in the Seattle Sex Survey
    Ian H Spicknall
    Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109 2029, USA
    Sex Transm Dis 36:465-72. 2009
    ..To better understand how and how often individuals bridge demographic groups in their sex partnerships, and to describe the epidemiologic characteristics of bridging and associations with history of sexually transmitted infection (STI)...
  47. pmc Does the lipR gene of tubercle bacilli have a role in tuberculosis transmission and pathogenesis?
    Katherine D Sheline
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Tuberculosis (Edinb) 89:114-9. 2009
    ....
  48. pmc Age- and gender-specific estimates of partnership formation and dissolution rates in the Seattle sex survey
    Sara J Nelson
    Department of Epidemiology, University of Washington, Center for AIDS and STD, Harborview Medical Center, 325 9thAve, Seattle, WA 98104, USA
    Ann Epidemiol 20:308-17. 2010
    ..Partnership formation and dissolution rates are primary determinants of sexually transmitted infection (STI) transmission dynamics...
  49. pmc Risk factors for otitis media and carriage of multiple strains of Haemophilus influenzae and Streptococcus pneumoniae
    J St Sauver
    University of Michigan, Ann Arbor, Michigan, USA
    Emerg Infect Dis 6:622-30. 2000
    ..influenzae. Carriage of multiple H. influenzae isolates, which was associated with exposure to smoking, history of allergies, and age 36 to 47 months, may increase risk for otitis media in children...
  50. pmc Distribution of novel and previously investigated virulence genes in colonizing and invasive isolates of Streptococcus agalactiae
    T C Smith
    Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
    Epidemiol Infect 135:1046-54. 2007
    ..Finally, the majority of serotype V isolates examined contained zero or only one of the genes tested, suggesting that much remains undiscovered regarding important virulence factors in isolates of this serotype...
  51. pmc Hygienic practices and acute respiratory illness in family and group day care homes
    J St Sauver
    Dept of Epidemiology, School of Public Health, Ann Arbor, MI 48109, USA
    Public Health Rep 113:544-51. 1998
    ..To describe hygiene practices in licensed group day care and family day care homes and the association between these practices and the prevalence of respiratory illnesses in the children in attendance...
  52. pmc Association of Mycobacterium tuberculosis PE PGRS33 polymorphism with clinical and epidemiological characteristics
    Sarah Talarico
    Department of Epidemiology, School of Public Health, University of Michigan, 109 Observatory Street, 4648 SPH I, Ann Arbor, MI 48109, USA
    Tuberculosis (Edinb) 87:338-46. 2007
    ..The association of significant changes to PE PGRS33 with clinical and epidemiological characteristics suggests that PE PGRS33 may have an important role in M. tuberculosis persistence...
  53. pmc Comparison of probe hybridization array typing to multilocus sequence typing for pathogenic Escherichia coli
    Sara E McNamara
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
    J Clin Microbiol 47:596-602. 2009
    ..Further refinement is needed to distinguish between closely related groups. For analysis of large bacterial collections, PHAT is a relatively time- and cost-efficient method and is ideal for a first level of analysis...
  54. pmc Variation of the Mycobacterium tuberculosis PE_PGRS 33 gene among clinical isolates
    Sarah Talarico
    Epidemiology Department, School of Public Health, University of Michigan, 109 S Observatory Street, Ann Arbor, MI 48109 2029, USA
    J Clin Microbiol 43:4954-60. 2005
    ..The observed genetic diversity of the PE_PGRS 33 gene supports its role in antigenic variation and can serve as a basis for future investigations of the function of the PE_PGRS 33 gene among clinical isolates...
  55. ncbi request reprint Determinants of co-colonization with group B streptococcus among heterosexual college couples
    Shannon D Manning
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
    Epidemiology 13:533-9. 2002
    ..Group B causes morbidity and mortality among newborns, pregnant women, and nonpregnant adults. Among adults, sexual and fecal-oral routes of transmission are hypothesized; this study addresses whether sexual transmission occurs...
  56. ncbi request reprint What's driving the decline in tuberculosis in Arkansas? A molecular epidemiologic analysis of tuberculosis trends in a rural, low-incidence population, 1997 2003
    Anne Marie France
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109 2029, USA
    Am J Epidemiol 166:662-71. 2007
    ..Declines in the overall incidence of tuberculosis in a population may not necessarily result from declines in active transmission...
  57. ncbi request reprint Epidemiology of urinary tract infections: incidence, morbidity, and economic costs
    Betsy Foxman
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor 48109 2029, USA
    Am J Med 113:5S-13S. 2002
    ..Financially, the estimated annual cost of community-acquired UTI is significant, at approximately $1.6 billion...
  58. ncbi request reprint Group B Streptococcus colonization in male and nonpregnant female university students: a cross-sectional prevalence study
    Sandra J Bliss
    Department of Internal Medicine and Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA
    Clin Infect Dis 34:184-90. 2002
    ..However, larger studies are needed to verify these findings...
  59. ncbi request reprint Prevalence and predictors of trimethoprim-sulfamethoxazole resistance among uropathogenic Escherichia coli isolates in Michigan
    Patricia D Brown
    Division of Infectious Diseases, Department of Internal Medicine, Wayne State University, School of Medicine, Detroit, MI, USA
    Clin Infect Dis 34:1061-6. 2002
    ..Recent antibiotic use is a risk factor for infection with a TMP-SMX-resistant isolate; patients who are infected with a TMP-SMX-resistant isolate and who are treated with this agent are at a higher risk for clinical failure...
  60. ncbi request reprint The role of horizontal gene transfer in the spread of trimethoprim-sulfamethoxazole resistance among uropathogenic Escherichia coli in Europe and Canada
    Matthew T Blahna
    Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor, 48109, USA
    J Antimicrob Chemother 57:666-72. 2006
    ....
  61. pmc Identification of the lipooligosaccharide biosynthesis gene lic2B as a putative virulence factor in strains of nontypeable Haemophilus influenzae that cause otitis media
    M M Pettigrew
    Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109 2029, USA
    Infect Immun 70:3551-6. 2002
    ..The lic2B gene was found 3.7 times more frequently among middle ear isolates than in throat isolates from children attending day care. These data suggest that a specific NT H. influenzae gene is associated with OM...
  62. pmc Distribution of insertion- and deletion-associated genetic polymorphisms among four Mycobacterium tuberculosis phospholipase C genes and associations with extrathoracic tuberculosis: a population-based study
    Y Kong
    Epidemiology Department, School of Public Health, University of Michigan, 109 S Observatory Street, Ann Arbor, MI 48109 2029, USA
    J Clin Microbiol 43:6048-53. 2005
    ..27; 95% confidence interval, 1.32 to 8.14). The data suggest that the plcD gene might play a more important role in the pathogenesis of thoracic TB than it does in the pathogenesis of extrathoracic TB...
  63. ncbi request reprint Duration of breastfeeding, daycare, and physician visits among infants 6 months and younger
    Melinda M Pettigrew
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
    Ann Epidemiol 13:431-5. 2003
    ..To describe the association between duration of breastfeeding and an illness requiring a visit to a health care provider within the past 30 days (IRHP) among infants </= 6 months...
  64. ncbi request reprint Lactation mastitis
    Cibele Barbosa-Cesnik
    Department of Epidemiology and Center for Molecular and Clinical Epidemiology of Infectious Diseases, University of Michigan, Ann Arbor 48109 2029, USA
    JAMA 289:1609-12. 2003
  65. pmc Both urinary and rectal Escherichia coli isolates are dominated by strains of phylogenetic group B2
    Lixin Zhang
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan48109 2029, USA
    J Clin Microbiol 40:3951-5. 2002
    ..Two subclusters existed within group B2 strains by ERIC typing. These subclusters were not evenly distributed between rectal and urine isolates and differed in virulence gene distribution...
  66. pmc Prevalence of antibiotic resistance in drinking water treatment and distribution systems
    Chuanwu Xi
    Department of Environmental Health Sciences, University of Michigan, Ann Arbor, Michigan, USA
    Appl Environ Microbiol 75:5714-8. 2009
    ..Water treatment might increase the antibiotic resistance of surviving bacteria, and water distribution systems may serve as an important reservoir for the spread of antibiotic resistance to opportunistic pathogens...
  67. ncbi request reprint Molecular epidemiology of Escherichia coli mediated urinary tract infections
    Lixin Zhang
    Department of Epidemiology, University of Michigan School of Public Health, USA
    Front Biosci 8:e235-44. 2003
    ..coli strains with different compositions of virulence genes...
  68. pmc Identification of a gene encoding heat-resistant agglutinin in Escherichia coli as a putative virulence factor in urinary tract infection
    Usha Srinivasan
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Clin Microbiol 41:285-9. 2003
    ..coli strains. The flanking genes suggest that in 1128-11, hra may be part of a novel variant of a pathogenicity island V...
  69. doi request reprint Vaginal and oral microbes, host genotype and preterm birth
    Usha Srinivasan
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA
    Med Hypotheses 73:963-75. 2009
    ..We posit that bacterial species that are common in perturbed vaginal and oral sites are associated with PTB through their interaction with the host immune system...
  70. ncbi request reprint Predictors for Haemophilus influenzae colonization, antibiotic resistance and for sharing an identical isolate among children attending 16 licensed day-care centers in Michigan
    Cibele Barbosa-Cesnik
    Department of Epidemiology, University of Michigan, School of Public Health, Ann Arbor, MI 48109, USA
    Pediatr Infect Dis J 25:219-23. 2006
    ..influenzae colonization, antibiotic resistance and predictors for colonization and sharing an identical isolate with at least 1 other child in the same day-care centers among children attending 16 day-care centers...
  71. ncbi request reprint Identification of risk factors for extrapulmonary tuberculosis
    Zhenhua Yang
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA
    Clin Infect Dis 38:199-205. 2004
    ..This study expands the knowledge base regarding the epidemiology of extrapulmonary tuberculosis and enhances our understanding of the relative contribution of host-related factors to the pathogenesis of tuberculosis...
  72. pmc Haemophilus influenzae: genetic variability and natural selection to identify virulence factors
    Janet R Gilsdorf
    Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Infect Immun 72:2457-61. 2004
  73. pmc Comparison of DNA dot blot hybridization and lancefield capillary precipitin methods for group B streptococcal capsular typing
    Stephanie M Borchardt
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Clin Microbiol 42:146-50. 2004
    ..The overall agreement between the methods was 95% (256 of 270 isolates typeable by both methods). We conclude that the DBCT method is a specific and useful alternative to the commonly used LS method...
  74. ncbi request reprint Bacterial genomic DNA isolation using sonication for microarray analysis
    Lixin Zhang
    Department of Epidemiology, University of Michigan, Ann Arbor 48109 2029, USA
    Biotechniques 39:640, 642, 644. 2005
  75. ncbi request reprint Escherichia coli mediated urinary tract infections: are there distinct uropathogenic E. coli (UPEC) pathotypes?
    Carl F Marrs
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, 48109 2029, USA
    FEMS Microbiol Lett 252:183-90. 2005
    ..coli genes involved in uropathogenesis and determination of their distribution and co-occurrences will further define UPEC pathotypes and allow for a more detailed analysis of how these pathotypes might differ in how they cause disease...
  76. ncbi request reprint Simultaneous detection of isoniazid, rifampin, and ethambutol resistance of Mycobacterium tuberculosis by a single multiplex allele-specific polymerase chain reaction (PCR) assay
    Zhenhua Yang
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109 2029, USA
    Diagn Microbiol Infect Dis 53:201-8. 2005
    ..1% and 97.5% for INH, 93.0% and 98.9 % for RIF, and 54.5% and 68.0 % for ethambutol. MAS-PCR provides a rapid, potentially more cost-effective, method of detecting multidrug-resistant TB...
  77. pmc Clinical relevance of Mycobacterium tuberculosis plcD gene mutations
    Zhenhua Yang
    Epidemiology Department, School of Public Health, University of Michigan, 109 S Observatory Street, Ann Arbor, MI 48109 2029, USA
    Am J Respir Crit Care Med 171:1436-42. 2005
    ..Our findings suggest that the plcD gene of M. tuberculosis is potentially involved in the pathogenesis of TB, and the clinical presentation of the disease may be influenced by the genetic variability of the plcD region...
  78. pmc Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae
    Usha Srinivasan
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
    Microb Drug Resist 17:121-4. 2011
    ..Although identified from patients at multiple hospitals, genotyping suggested that the strains are closely related. The new phenotype shows increased sensitivity to clindamycin in the presence of erythromycin...
  79. pmc Vaginal douching and risk of preterm birth among African American women
    Dawn P Misra
    Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
    Am J Obstet Gynecol 196:140.e1-8. 2007
    ..The purpose of this study was to examine how vaginal douching may influence risk of preterm birth...
  80. pmc Variation and predictors of vaginal douching behavior
    Dawn P Misra
    Department of Health Behavior and Health Education, University of Michigan School of Public Health, 1420 Washington Heights, Ann Arbor, MI 48109, USA
    Womens Health Issues 16:275-82. 2006
    ..Vaginal douching is a widespread practice among American women. Little research has been done examining variation in the practice or identifying risk factors...
  81. doi request reprint Prepregnancy body mass index and gestational age-dependent changes in lipid levels during pregnancy
    Anjel Vahratian
    Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA
    Obstet Gynecol 116:107-13. 2010
    ..To examine the effect of maternal prepregnancy overweight and obesity on gestational age-dependent variation in lipid levels during pregnancy...
  82. ncbi request reprint Achieving safe motherhood: applying a life course and multiple determinants perinatal health framework in public health
    Dawn P Misra
    Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, 48109, USA
    Womens Health Issues 16:159-75. 2006
    ..Our intent is to influence how policy makers, public health professionals, clinicians, and researchers approach safe motherhood...
  83. ncbi request reprint Integrated perinatal health framework. A multiple determinants model with a life span approach
    Dawn P Misra
    Women s and Children s Health Policy Center, Department of Population and Family Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
    Am J Prev Med 25:65-75. 2003
    ..A new approach is needed if we are to achieve improvements in perinatal health...
  84. ncbi request reprint Infant mortality among singletons and twins in the United States during 2 decades: effects of maternal age
    Dawn P Misra
    Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
    Pediatrics 110:1163-8. 2002
    ..The objective of this study was to characterize the relationship between maternal age and infant mortality in singleton and twin births in the United States...
  85. ncbi request reprint Maternal smoking and birth weight: interaction with parity and mother's own in utero exposure to smoking
    Dawn P Misra
    Department of Health Behavior and Health Education, University of Michigan School of Public Health, 1420 Washington Heights M5015, Ann Arbor, MI 48109, USA
    Epidemiology 16:288-93. 2005
    ..We examined maternal smoking in a cohort study for which data from 3 generations were available to examine maternal characteristics and exposures from a life-course perspective...
  86. pmc Exposures to airborne particulate matter and adverse perinatal outcomes: a biologically plausible mechanistic framework for exploring potential effect modification by nutrition
    Srimathi Kannan
    Department of Environmental Health Sciences, Human Nutrition Program, University of Michigan, Ann Arboe, Michigan 48109 2029, USA
    Environ Health Perspect 114:1636-42. 2006
    ....
  87. ncbi request reprint Correlates of antibiotic-resistant group B streptococcus isolated from pregnant women
    Shannon D Manning
    Department of Epidemiology and Center for Molecular and Clinical Epidemiology of Infectious Diseases, University of Michigan School of Public Health, Ann Arbor, Michigan 48109 0276, USA
    Obstet Gynecol 101:74-9. 2003
    ..A better understanding of factors associated with antibiotic resistance is needed to minimize group B streptococcus disease risks and to maximize effective chemoprophylaxis...
  88. ncbi request reprint Clonal groups and the spread of resistance to trimethoprim-sulfamethoxazole in uropathogenic Escherichia coli
    Anne Marie France
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA
    Clin Infect Dis 40:1101-7. 2005
    ..coli isolates from a university population in Michigan...
  89. ncbi request reprint Risk factors for recurrent vulvovaginal candidiasis in women receiving maintenance antifungal therapy: results of a prospective cohort study
    Divya A Patel
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Mich, USA
    Am J Obstet Gynecol 190:644-53. 2004
    ....
  90. ncbi request reprint Variations in 10 putative uropathogen virulence genes among urinary, faecal and peri-urethral Escherichia coli
    Carl F Marrs
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor 48109, USA
    J Med Microbiol 51:138-42. 2002
    ..Peri-urethral isolates were found to have frequencies of these 10 genes that differed from those found for both UTI and faecal isolates...
  91. doi request reprint The association between handwashing practices and illness symptoms among college students living in a university dormitory
    Jyothi Thumma
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
    Am J Infect Control 37:70-2. 2009
    ..0001) and after a bowel movement (84% vs 78%; P = .14). Identifying new strategies to increase handwashing may help prevent infectious disease transmission in residence hall environments...
  92. pmc Mycobacterium tuberculosis PE_PGRS16 and PE_PGRS26 genetic polymorphism among clinical isolates
    Sarah Talarico
    Department of Epidemiology, School of Public Health, University of Michigan, 109 S Observatory Street, 4648 SPH I, Ann Arbor, MI 48109 2029, USA
    Tuberculosis (Edinb) 88:283-94. 2008
    ....
  93. pmc DNA polymorphisms in the pepA and PPE18 genes among clinical strains of Mycobacterium tuberculosis: implications for vaccine efficacy
    Andrea M Hebert
    Epidemiology Department, School of Public Health, University of Michigan, 109 S Observatory Street, Ann Arbor, MI 48109 2029, USA
    Infect Immun 75:5798-805. 2007
    ..Thus, immunity induced by Mtb72F may not recognize a proportion of M. tuberculosis clinical strains...
  94. ncbi request reprint Desquamative inflammatory vaginitis: an exploratory case-control study
    E Claire Newbern
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
    Ann Epidemiol 12:346-52. 2002
    ..To investigate potential risk factors for desquamative inflammatory vaginitis (DIV), a rare but severe form of vaginitis. We are aware of no other controlled studies of DIV...
  95. ncbi request reprint Antibiotic prescribing for otitis media: how well does it match published guidelines?
    Laura N McEwen
    University of Michigan, Ann Arbor, MI 48109, USA
    Pharmacoepidemiol Drug Saf 12:213-9. 2003
    ..For persons of all ages with recurrent infections, the prescribed duration was often shorter than suggested (10 days versus > or = 14 days). There were only modest variations by urban/rural location or provider type...
  96. ncbi request reprint The epidemiology of acute pyelonephritis in South Korea, 1997-1999
    Moran Ki
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA
    Am J Epidemiol 160:985-93. 2004
    ..40) increased the risk of any recurrence. Pyelonephritis has a clear seasonal pattern and high rate of recurrence. The incidence of hospitalization for pyelonephritis in South Korea is similar to that in the United States and Canada...
  97. pmc Evaluation of genotyping large numbers of Escherichia coli isolates by enterobacterial repetitive intergenic consensus-PCR
    Kiersten J Meacham
    Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Clin Microbiol 41:5224-6. 2003
    ..ERIC-PCR should not be used as the sole determinant of genetic similarity when typing large numbers of bacterial isolates via computer software...
  98. pmc Risk factors for bacterial vaginosis during pregnancy among African American women
    Britton Trabert
    Department of Epidemiology, University of Washington School of Public Health and Community Medicine, Seattle, WA, USA
    Am J Obstet Gynecol 197:477.e1-8. 2007
    ..The objective of the study was to examine risk factors for bacterial vaginosis (BV) during pregnancy among African American women...
  99. pmc Ethical conflicts in public health research and practice: antimicrobial resistance and the ethics of drug development
    Allison E Aiello
    Center for Social Epidemiology and Population Health, Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48104 2548, USA
    Am J Public Health 96:1910-4. 2006
    ....
  100. pmc Use of pulsed-field gel electrophoresis, enterobacterial repetitive intergenic consensus typing, and automated ribotyping to assess genomic variability among strains of nontypeable Haemophilus influenzae
    M M Pettigrew
    Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109 2029, USA
    J Clin Microbiol 40:660-2. 2002
    ..PFGE was the most discriminatory of the techniques. ERIC-PCR provides a useful screen but should not replace other techniques as the sole method to group NT H. influenzae strains...

Research Grants9

  1. GBS: Epidemiologic Characterization for Gene Discovery
    Betsy Foxman; Fiscal Year: 2003
    ..A better understanding of the molecular epidemiology and the identification of new GBS virulence genes will facilitate the discovery of new therapies and prevention strategies for GBS disease. ..
  2. GBS: Epidemiologic Characterization for Gene Discovery
    Betsy Foxman; Fiscal Year: 2006
    ..A better understanding of the molecular epidemiology and the identification of new GBS virulence genes will facilitate the discovery of new therapies and prevention strategies for GBS disease. ..
  3. GBS: Epidemiologic Characterization for Gene Discovery
    Betsy Foxman; Fiscal Year: 2007
    ..A better understanding of the molecular epidemiology and the identification of new GBS virulence genes will facilitate the discover of new therapies and prevention strategies for GBS disease. ..
  4. Interdisciplinary Training Program in Infectious Diseases
    Betsy Foxman; Fiscal Year: 2007
    ..In this renewal, we are requesting five pre-doctoral positions. ..
  5. Oral and Vaginal Microbes, Human Genotype, and Preterm Birth
    Betsy Foxman; Fiscal Year: 2009
    ..For this proposal we have the great advantage of exploring these hypotheses using already collected specimens and data as part of completed studies of preterm birth. ..
  6. Oral and Vaginal Microbes, Human Genotype, and Preterm Birth
    Dawn P Misra; Fiscal Year: 2010
    ..For this proposal we have the great advantage of exploring these hypotheses using already collected specimens and data as part of completed studies of preterm birth. ..