Jack F Fowler

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Loss of biological effect in prolonged fraction delivery
    Jack F Fowler
    Department of Human Oncology, Medical School, University of Wisconsin, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 59:242-9. 2004
  2. doi request reprint Sensitivity analysis of parameters in linear-quadratic radiobiologic modeling
    Jack F Fowler
    Department of Human Oncology, School of Medicine, University of Wisconsin, Madison, WI, USA
    Int J Radiat Oncol Biol Phys 73:1532-7. 2009
  3. ncbi request reprint A challenge to traditional radiation oncology
    Jack F Fowler
    Department of Human Oncology, Medical School of the University of Wisconsin, Madison, WI, USA
    Int J Radiat Oncol Biol Phys 60:1241-56. 2004
  4. ncbi request reprint Development of radiobiology for oncology-a personal view
    Jack F Fowler
    Human Oncology and Medical Physics, University of Wisconsin Medical School, Madison, WI 53792, USA
    Phys Med Biol 51:R263-86. 2006
  5. ncbi request reprint On the inclusion of proliferation in tumour control probability calculations for inhomogeneously irradiated tumours
    Wolfgang A Tome
    Department of Human Oncology, University of Wisconsin Medical School, K4 344 CSC 600 Highland Avenue, Madison, WI 53792, USA
    Phys Med Biol 48:N261-8. 2003
  6. ncbi request reprint The radiobiology of prostate cancer including new aspects of fractionated radiotherapy
    Jack F Fowler
    Emeritus of Medical School of Wisconsin University, Department of Human Oncology, University of Wisconsin Madison, USA
    Acta Oncol 44:265-76. 2005
  7. doi request reprint Correction to Kasibhatla et al. How much radiation is the chemotherapy worth in advanced head and neck cancer? (Int j radiat oncol biol phys 2007;68:1491-1495)
    Jack F Fowler
    Department of Human Oncology and Medical Physics, University of Wisconsin, Madison, WI, USA
    Int J Radiat Oncol Biol Phys 71:326-9. 2008
  8. ncbi request reprint Acute radiation reactions in oral and pharyngeal mucosa: tolerable levels in altered fractionation schedules
    Jack F Fowler
    Department of Human Oncology K4 316, University of Wisconsin, 600 Highland Ave, Madison, WI 53792, USA
    Radiother Oncol 69:161-8. 2003
  9. ncbi request reprint What hypofractionated protocols should be tested for prostate cancer?
    Jack F Fowler
    Department of Human Oncology, University of Wisconsin Madison, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 56:1093-104. 2003
  10. ncbi request reprint Reduction in radiation dose to lung and other normal tissues using helical tomotherapy to treat lung cancer, in comparison to conventional field arrangements
    Rufus A Scrimger
    Department of Human Oncology, University of Wisconsin, Madison, Wisconsin 53792, USA
    Am J Clin Oncol 26:70-8. 2003

Detail Information

Publications26

  1. ncbi request reprint Loss of biological effect in prolonged fraction delivery
    Jack F Fowler
    Department of Human Oncology, Medical School, University of Wisconsin, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 59:242-9. 2004
    ..In this article, we model repair rates for a range of doses per fraction and draw conclusions...
  2. doi request reprint Sensitivity analysis of parameters in linear-quadratic radiobiologic modeling
    Jack F Fowler
    Department of Human Oncology, School of Medicine, University of Wisconsin, Madison, WI, USA
    Int J Radiat Oncol Biol Phys 73:1532-7. 2009
    ..The present article shows how much the linear-quadratic (LQ) (calculated biologically equivalent dose [BED] varies when individual parameters of the LQ formula are varied by +/-20% and by 1%...
  3. ncbi request reprint A challenge to traditional radiation oncology
    Jack F Fowler
    Department of Human Oncology, Medical School of the University of Wisconsin, Madison, WI, USA
    Int J Radiat Oncol Biol Phys 60:1241-56. 2004
    ....
  4. ncbi request reprint Development of radiobiology for oncology-a personal view
    Jack F Fowler
    Human Oncology and Medical Physics, University of Wisconsin Medical School, Madison, WI 53792, USA
    Phys Med Biol 51:R263-86. 2006
    ..This is the very personal story of what I saw happening in the subject, decade by decade. I was happy to experience all this together with scientists in many other countries, and our own, along the way...
  5. ncbi request reprint On the inclusion of proliferation in tumour control probability calculations for inhomogeneously irradiated tumours
    Wolfgang A Tome
    Department of Human Oncology, University of Wisconsin Medical School, K4 344 CSC 600 Highland Avenue, Madison, WI 53792, USA
    Phys Med Biol 48:N261-8. 2003
    ....
  6. ncbi request reprint The radiobiology of prostate cancer including new aspects of fractionated radiotherapy
    Jack F Fowler
    Emeritus of Medical School of Wisconsin University, Department of Human Oncology, University of Wisconsin Madison, USA
    Acta Oncol 44:265-76. 2005
    ..Monotherapy by brachytherapy for low-risk cancer prostate using two to four fractions in a few days can give even higher biological effects on the tumors...
  7. doi request reprint Correction to Kasibhatla et al. How much radiation is the chemotherapy worth in advanced head and neck cancer? (Int j radiat oncol biol phys 2007;68:1491-1495)
    Jack F Fowler
    Department of Human Oncology and Medical Physics, University of Wisconsin, Madison, WI, USA
    Int J Radiat Oncol Biol Phys 71:326-9. 2008
    ....
  8. ncbi request reprint Acute radiation reactions in oral and pharyngeal mucosa: tolerable levels in altered fractionation schedules
    Jack F Fowler
    Department of Human Oncology K4 316, University of Wisconsin, 600 Highland Ave, Madison, WI 53792, USA
    Radiother Oncol 69:161-8. 2003
    ..To investigate whether a predictive estimate can be obtained for a 'tolerance level' of acute oral and pharyngeal mucosal reactions in patients receiving head and neck radiotherapy, using an objective set of dose and time data...
  9. ncbi request reprint What hypofractionated protocols should be tested for prostate cancer?
    Jack F Fowler
    Department of Human Oncology, University of Wisconsin Madison, Madison, WI 53792, USA
    Int J Radiat Oncol Biol Phys 56:1093-104. 2003
    ..We analyze here possible high-gain/low-risk hypofractionated protocols for prostate cancer to test this suggestion...
  10. ncbi request reprint Reduction in radiation dose to lung and other normal tissues using helical tomotherapy to treat lung cancer, in comparison to conventional field arrangements
    Rufus A Scrimger
    Department of Human Oncology, University of Wisconsin, Madison, Wisconsin 53792, USA
    Am J Clin Oncol 26:70-8. 2003
    ..This has important implications for dose escalation strategies in the future...
  11. ncbi request reprint On cold spots in tumor subvolumes
    Wolfgang A Tome
    Department of Human Oncology, University of Wisconsin Medical School, CSc, Madison 53792, USA
    Med Phys 29:1590-8. 2002
    ..The effect of cold regions on TCP can be minimized if the EUD associated with the target DVH is constrained to be equal to or larger than the prescription dose...
  12. ncbi request reprint Repair between dose fractions: a simpler method of analyzing and reporting apparently biexponential repair
    Jack F Fowler
    Department of Human Oncology, University of Wisconsin Medical School, K4 316, 600 Highland Avenue, Madison, Wisconsin 53792, USA
    Radiat Res 158:141-51. 2002
    ..A much larger proportion of damage would therefore remain unrepaired at several half-times than is estimated by current mono- or biexponential models. The practical implications for clinical radiotherapy are important...
  13. ncbi request reprint High-dose-rate brachytherapy-. High-dose, high-tech, and high results
    Daniel G Petereit
    Int J Radiat Oncol Biol Phys 55:1159-61. 2003
  14. ncbi request reprint Isn't it reasonable to ask for fraction numbers?
    Jack F Fowler
    Int J Radiat Oncol Biol Phys 72:313-4. 2008
  15. ncbi request reprint The optimal fraction size in high-dose-rate brachytherapy: dependency on tissue repair kinetics and low-dose rate
    Peter Sminia
    Department of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands p sminia vumc nl
    Int J Radiat Oncol Biol Phys 52:844-9. 2002
    ....
  16. ncbi request reprint Stereotactic hypofractionated accurate radiotherapy of the prostate (SHARP), 33.5 Gy in five fractions for localized disease: first clinical trial results
    Berit L Madsen
    Section of Radiation Oncology, Virginia Mason Medical Center, Seattle, WA 98101, USA
    Int J Radiat Oncol Biol Phys 67:1099-105. 2007
    ..To evaluate the feasibility and toxicity of stereotactic hypofractionated accurate radiotherapy (SHARP) for localized prostate cancer...
  17. ncbi request reprint Comments on "Comparison of in vitro and in vivo alpha/beta ratios for prostate cancer"
    Alexandru Daşu
    Phys Med Biol 50:L1-4; author reply L5-8. 2005
  18. ncbi request reprint The prospects for new treatments for prostate cancer
    Jack F Fowler
    Int J Radiat Oncol Biol Phys 52:3-5. 2002
  19. ncbi request reprint The effect of fraction time in intensity modulated radiotherapy: theoretical and experimental evaluation of an optimization problem (the real conclusions): in regard to Mu et al. Radiotherapy on Oncology 2003; 68: 181-87
    Wofgang A Tomé
    Radiother Oncol 72:113-4; author reply 114-5. 2004
  20. ncbi request reprint Yes, the alpha/beta ratio for prostate cancer is low or "methinks the lady doth protest too much...about a low alpha/beta that is"
    Christopher R King
    Int J Radiat Oncol Biol Phys 54:626-7; author reply 627-8. 2002
  21. ncbi request reprint Should single or distributed parameters be used to explain the steepness of tumour control probability curves?
    Alexandru Daşu
    Department of Radiation Sciences, Umea University, S 901 85 Umea, Sweden
    Phys Med Biol 48:387-97. 2003
    ..This contradiction suggests that single values for the parameters are not likely to explain reasonably the clinical observations and that some distributions of input parameters should be taken into consideration...
  22. ncbi request reprint How low is the alpha/beta ratio for prostate cancer? In regard to Wang et al., IJROBP 2003;55:194-203
    Jack F Fowler
    Int J Radiat Oncol Biol Phys 57:593-5; author reply 595-6. 2003
  23. ncbi request reprint Dose rate in external beam radiotherapy for prostate cancer: an overlooked confounding variable?
    James S Welsh
    Urology 62:204-6. 2003
  24. ncbi request reprint Walking forward: the South Dakota Native American project
    Daniel G Petereit
    John T Vucurevich Cancer Institute, Rapid City, SD 57701, USA
    J Cancer Educ 20:65-70. 2005
    ..It is hypothesized that a conventional course of cancer treatment lasting 6 to 8 weeks may be a barrier...
  25. ncbi request reprint Theoretical simulation of oxygen tension measurement in the tissue using a microelectrode: II. Simulated measurements in tissues
    Iuliana Toma-Daşu
    Department of Radiation Sciences, Umea University, S 901 85 Umea, Sweden
    Radiother Oncol 64:109-18. 2002
    ....
  26. ncbi request reprint Influence of overall treatment time and radiobiological parameters on biologically effective doses in cervical cancer patients treated with radiation therapy alone
    Anna Gasinska
    Laboratory of Radiation Biology, Department of Radiation Therapy, Centre of Oncology, Krakow, Poland
    Acta Oncol 43:657-66. 2004
    ..037), BrdUrdLI </= 8.8% (p=0.003), tumour aneuploidy (p=0.043), and BED10 </= 103 Gy (p=0.017). The examined tumour biological parameters should be taken into account for RT and provide a basis for adjuvant RT...