Research Topics
| S A FoundsSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Bridging global gene expression candidates in first trimester placentas with susceptibility loci from linkage studies of preeclampsiaSandra A Founds
Department of Health Promotion and Development, School of Nursing, Member, Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, PA 15261, USA
J Perinat Med 39:361-8. 2011..These loci and related candidate genes are set to substantially improve insights into the first trimester pathogenesis of this pregnancy disorder...
Variations in discovery-based preeclampsia candidate genesSandra A Founds
Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Clin Transl Sci 5:333-9. 2012..The integrative approach that was implemented begins to translate the 36 candidates toward clinical utility as a screening modality for preeclampsia...
Is there evidence of separate inflammatory or metabolic forms of preeclampsia?Sandra A Founds
School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA
Hypertens Pregnancy 30:1-10. 2011..To examine whether high insulin resistance versus high inflammation identifies subtypes of preeclampsia...
Gene expression in first trimester preeclampsia placentaSandra A Founds
Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA
Biol Res Nurs 13:134-9. 2011..The goal of this study was to further validate eight candidate genes identified in a microarray analysis of first trimester placentas in preeclampsia...
LAIR2 localizes specifically to sites of extravillous trophoblast invasionS A Founds
School of Nursing, University of Pittsburgh, Pittsburgh, PA, USA
Placenta 31:880-5. 2010..Neither the localization nor the function of LAIR2 has been examined in the placenta. Localization studies were conducted in placental tissues to determine the precise sites of LAIR2 mRNA production and protein binding...
Introducing systems biology for nursing scienceSandra A Founds
Department of Health Promotion and Development, School of Nursing, and Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15090, USA
Biol Res Nurs 11:73-80. 2009..Systems biology has the potential to advance the research and practice goals of the National Institute for Nursing Research in the National Institutes of Health Roadmap initiative...
Altered global gene expression in first trimester placentas of women destined to develop preeclampsiaS A Founds
School of Nursing, Department of Health Promotion and Development, University of Pittsburgh, Pittsburgh, PA 15261, USA
Placenta 30:15-24. 2009..Accordingly, we hypothesized dysregulation of global gene expression in first trimester placentas of women who later manifested preeclampsia...
Participating in research for pregnancy complicated by breechSandra A Founds
University of Pittsburgh, School of Nursing Pittsburgh, Pennsylvania 15261, USA
Health Care Women Int 28:573-89. 2007..Gauging research protocols to fit questions of concern, women's and providers' experiences, and practice settings supports participant-centered pregnancy risk reduction research that could decrease maternal mortality...
Clinical implications from an exploratory study of postural management of breech presentationSandra A Founds
Department of Health Promotion and Development, University of Pittsburgh School of Nursing, Pittsburgh, PA 15261, USA
J Midwifery Womens Health 51:292-6. 2006..At least one adequately powered trial that controls for parity and gestational age is needed to determine whether knee-chest postural management results in no effect, a small, or small to moderate clinically significant effect...
Development of high-fidelity simulated clinical experiences for baccalaureate nursing studentsSandra A Founds
Department of Health Promotion and Development, School of Nursing, University of Pittsburgh, 3500 Victoria Street, Pittsburgh, PA 15261, USA
J Prof Nurs 27:5-9. 2011..The benefits of simulation experiences for students are discussed and a template for the nurse educator is provided to help develop simulations. This system is illustrated by an example from a high-risk antepartum obstetric scenario...
LAIR2-expressing extravillous trophoblasts associate with maternal spiral arterioles undergoing physiologic conversionS A Founds
School of Nursing, University of Pittsburgh, USA
Placenta 34:248-55. 2013..Based on these findings, we suggest that LAIR2-expressing EVT may play an important role in the remodeling of maternal spiral arterioles...
Maternal posture for cephalic version of breech presentation: a review of the evidenceSandra A Founds
University of Pennsylvania School of Nursing, Philadelphia, PA, USA
Birth 32:137-44. 2005..CONCLUSIONS: Further research based on explicit theory and improved methods, including sufficient sample size, is needed to determine whether maternal posture promotes cephalic version for pregnant women with breech presentation...
Women's and providers' experiences of breech presentation in Jamaica: a qualitative studySandra A Founds
Department of Health Promotion and Development, University of Pittsburgh School of Nursing, Pittsburgh, Pennsylvania 15261, USA
Int J Nurs Stud 44:1391-9. 2007..Most research on breech relates to medical management of the malpresentation. Little is known about women's or providers' experiences of breech, an obstetrical complication...
