Gary N Foulks

Summary

Affiliation: University of Louisville
Country: USA

Publications

  1. doi request reprint Treatment of dry eye disease by the non-ophthalmologist
    Gary N Foulks
    Department of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, 301 East Muhammad Ali Boulevard, Louisville, KY 40202, USA
    Rheum Dis Clin North Am 34:987-1000, x. 2008
  2. ncbi request reprint Meibomian gland dysfunction: the past, present, and future
    Gary N Foulks
    Department of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Eye Contact Lens 36:249-53. 2010
  3. pmc Topical azithromycin therapy for meibomian gland dysfunction: clinical response and lipid alterations
    Gary N Foulks
    Department of Ophthalmology and Vision Science, University of Louisville, 301 E Muhammad Ali Blvd, Louisville, KY 40202, USA
    Cornea 29:781-8. 2010
  4. doi request reprint Clinical evaluation of the efficacy of PEG/PG lubricant eye drops with gelling agent (HP-Guar) for the relief of the signs and symptoms of dry eye disease: a review
    Gary N Foulks
    Professor of Ophthalmology, University of Kentucky, Louisville, Kentucky, USA
    Drugs Today (Barc) 43:887-96. 2007
  5. ncbi request reprint Prolonging contact lens wear and making contact lens wear safer
    Gary N Foulks
    University of Louisville, School of Medicine, Louisville, Kentucky 40202, USA
    Am J Ophthalmol 141:369-373. 2006
  6. pmc Wax-tear and meibum protein, wax-β-carotene interactions in vitro using infrared spectroscopy
    Samad Faheem
    Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, 301 E Muhammad Ali Blvd, Louisville, KY 40202, USA
    Exp Eye Res 100:32-9. 2012
  7. ncbi request reprint Expression in human ocular surface tissues of the GalNAc-transferases that initiate mucin-type O-glycosylation
    Yoannis Imbert
    Department of Molecular, Cellular and Craniofacial Biology, School of Dentistry, University of Louisville, Louisville, KY 40292, USA
    Cornea 25:1193-9. 2006
  8. pmc Human meibum lipid conformation and thermodynamic changes with meibomian-gland dysfunction
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Invest Ophthalmol Vis Sci 52:3805-17. 2011
  9. pmc Differences in human meibum lipid composition with meibomian gland dysfunction using NMR and principal component analysis
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Invest Ophthalmol Vis Sci 53:337-47. 2012
  10. doi request reprint Factors affecting evaporation rates of tear film components measured in vitro
    Douglas Borchman
    Department of Ophthalmology, University of Louisville, Louisville, KY, USA
    Eye Contact Lens 35:32-7. 2009

Collaborators

Detail Information

Publications44

  1. doi request reprint Treatment of dry eye disease by the non-ophthalmologist
    Gary N Foulks
    Department of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, 301 East Muhammad Ali Boulevard, Louisville, KY 40202, USA
    Rheum Dis Clin North Am 34:987-1000, x. 2008
    ..The array of potential treatments both topical and systemic has evolved to provide a much more targeted and effective arsenal from which the clinician may choose...
  2. ncbi request reprint Meibomian gland dysfunction: the past, present, and future
    Gary N Foulks
    Department of Ophthalmology and Visual Sciences, University of Louisville School of Medicine, Louisville, KY 40202, USA
    Eye Contact Lens 36:249-53. 2010
    ..To recount the historic evaluation of meibomian gland dysfunction (MGD) and describe new techniques to monitor disease and therapy...
  3. pmc Topical azithromycin therapy for meibomian gland dysfunction: clinical response and lipid alterations
    Gary N Foulks
    Department of Ophthalmology and Vision Science, University of Louisville, 301 E Muhammad Ali Blvd, Louisville, KY 40202, USA
    Cornea 29:781-8. 2010
    ....
  4. doi request reprint Clinical evaluation of the efficacy of PEG/PG lubricant eye drops with gelling agent (HP-Guar) for the relief of the signs and symptoms of dry eye disease: a review
    Gary N Foulks
    Professor of Ophthalmology, University of Kentucky, Louisville, Kentucky, USA
    Drugs Today (Barc) 43:887-96. 2007
    ....
  5. ncbi request reprint Prolonging contact lens wear and making contact lens wear safer
    Gary N Foulks
    University of Louisville, School of Medicine, Louisville, Kentucky 40202, USA
    Am J Ophthalmol 141:369-373. 2006
    ..To summarize the present status of safety and efficacy of contact lens wear...
  6. pmc Wax-tear and meibum protein, wax-β-carotene interactions in vitro using infrared spectroscopy
    Samad Faheem
    Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, 301 E Muhammad Ali Blvd, Louisville, KY 40202, USA
    Exp Eye Res 100:32-9. 2012
    ..Among the tear fluid proteins studied, mucin is the most likely to influence the conformation and carbonyl environment of meibum at the tear film surface...
  7. ncbi request reprint Expression in human ocular surface tissues of the GalNAc-transferases that initiate mucin-type O-glycosylation
    Yoannis Imbert
    Department of Molecular, Cellular and Craniofacial Biology, School of Dentistry, University of Louisville, Louisville, KY 40292, USA
    Cornea 25:1193-9. 2006
    ..Therefore, we determined the expression of the ppGaNTase isoforms in normal human ocular surface tissues and the conjunctival epithelium from patients with aqueous-deficient dry eye...
  8. pmc Human meibum lipid conformation and thermodynamic changes with meibomian-gland dysfunction
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Invest Ophthalmol Vis Sci 52:3805-17. 2011
    ..In this study the conformation of Md was quantified to test this finding...
  9. pmc Differences in human meibum lipid composition with meibomian gland dysfunction using NMR and principal component analysis
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Invest Ophthalmol Vis Sci 53:337-47. 2012
    ..This tool was used to measure changes in human meibum composition with meibomian gland dysfunction (MGD)...
  10. doi request reprint Factors affecting evaporation rates of tear film components measured in vitro
    Douglas Borchman
    Department of Ophthalmology, University of Louisville, Louisville, KY, USA
    Eye Contact Lens 35:32-7. 2009
    ..The impact of temperature, air flow, and humidity on the evaporation rate of tears was measured in vitro...
  11. pmc Physical changes in human meibum with age as measured by infrared spectroscopy
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA
    Ophthalmic Res 44:34-42. 2010
    ..This study also serves as a foundation to examine meibum conformational differences in meibum from people with meibomian gland dysfunction...
  12. doi request reprint Topical azithromycin and oral doxycycline therapy of meibomian gland dysfunction: a comparative clinical and spectroscopic pilot study
    Gary N Foulks
    Department of Surgery, Robley Rex Veterans Affairs Medical Center, Louisville, KY, USA
    Cornea 32:44-53. 2013
    ....
  13. pmc Changes in human meibum lipid composition with age using nuclear magnetic resonance spectroscopy
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Invest Ophthalmol Vis Sci 53:475-82. 2012
    ..Human tear film stability decreases with increasing age. In this study, the changes in meibum composition were measured in search of markers of tear film instability...
  14. pmc Analysis of the composition of lipid in human meibum from normal infants, children, adolescents, adults, and adults with meibomian gland dysfunction using ¹H-NMR spectroscopy
    Rashmi K Shrestha
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Invest Ophthalmol Vis Sci 52:7350-8. 2011
    ..The results highlight the applicability of (1)H-NMR spectroscopy for the quantitative analysis of waxes, cholesteryl esters, and glycerides in meibum lipid (ML)...
  15. pmc Changes in human meibum lipid with meibomian gland dysfunction using principal component analysis
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, 301 E Muhammad Ali Blvd, Louisville, KY 40202, USA
    Exp Eye Res 91:246-56. 2010
    ..This study also demonstrates the power of the combination of infrared spectroscopy and PCA as a diagnostic tool that discriminates between Mn and Md...
  16. pmc Glycoprotein 340 in normal human ocular surface tissues and tear film
    Marcia M Jumblatt
    Department of Ophthalmology and Visual Science, University of Louisville School of Medicine, Louisville, KY 40292, USA
    Infect Immun 74:4058-63. 2006
    ..These results suggest that gp340 is a normal component of the tear film and that the glycoprotein may function as a bacterial agglutinin...
  17. doi request reprint Confirmation of changes in human meibum lipid infrared spectra with age using principal component analysis
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Curr Eye Res 35:778-86. 2010
    ..In this study, the remaining 99% of the spectral frequencies were analyzed to gain insight into changes that occur in meibum with age...
  18. ncbi request reprint Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications
    Benjamin D Sullivan
    TearLab Corporation, San Diego, California, USADepartment of Ophthalmology, Ludwig Maximilian University, Munich, GermanyKentucky Lions Eye Center, University of Louisville, Louisville, Kentucky, USACollege of Optometry, University of Houston, Houston, Texas, USARoyal Victoria Infirmary and Newcastle University, Newcastle upon Tyne, EnglandDepartment of Ophthalmology, University of Dusseldorf, GermanyDepartment of Ophthalmology, Georgetown University, Washington, District of Columbia, USADepartment of Ophthalmology, George Washington University, Washington, District of Columbia, USA
    Acta Ophthalmol 92:161-6. 2014
    ..To evaluate the relationship between signs and symptoms of dry eye disease (DED) in a clinic-based population...
  19. doi request reprint Contact lenses and the rate of evaporation measured in vitro; the influence of wear, squalene and wax
    Sravya Vishnubhatla
    Department of Ophthalmology and Visual Sciences, University of Louisville, 301 E Muhammad Ali Blvd, Louisville, KY 40202, USA
    Cont Lens Anterior Eye 35:277-81. 2012
    ..If the ERTCL could be minimized in vivo, contact lenses could potentially be used to relieve dry eye symptoms in patients with evaporative dry eye...
  20. doi request reprint Improving awareness, identification, and management of meibomian gland dysfunction
    Gary N Foulks
    Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, Kentucky, USA
    Ophthalmology 119:S1-12. 2012
    ....
  21. ncbi request reprint Temperature-induced conformational changes in human tearlipids hydrocarbon chains
    Douglas Borchman
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY 40202, USA
    Biopolymers 87:124-33. 2007
    ....
  22. doi request reprint Quantification of human sebum on skin and human meibum on the eye lid margin using Sebutape®, spectroscopy and chemical analysis
    Zara Ashraf
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky, USA
    Curr Eye Res 36:553-62. 2011
    ....
  23. doi request reprint MUC1 and estrogen receptor alpha gene polymorphisms in dry eye patients
    Yoannis Imbert
    Department of Biochemistry and Molecular Biology, School of Medicine, University of Louisville, Louisville, KY 40292, USA
    Exp Eye Res 88:334-8. 2009
    ..Therefore, mechanisms influencing protection of the ocular surface against inflammation and damage in different types of dry eye disease warrant further investigation particularly in relation to MUC1 genotype...
  24. ncbi request reprint Pharmacological management of dry eye in the elderly patient
    Gary N Foulks
    Arthur and Virginia Keeney Professor of Ophthalmology, Department of Ophthalmology and Vision Science, University of Louisville School of Medicine, Louisville, Kentucky 40202, USA
    Drugs Aging 25:105-18. 2008
    ..In the elderly patient it is important to recognize the physical and cognitive limitations that will influence the selection of appropriate topical medication...
  25. pmc New testing options for diagnosing and grading dry eye disease
    Gary N Foulks
    Department of Ophthalmology and Vision Science, University of Louisville, Louisville, Kentucky Electronic address
    Am J Ophthalmol 157:1122-9. 2014
    ..To describe new options for diagnosis and severity grading of dry eye disease...
  26. ncbi request reprint Spectroscopic evaluation of human tear lipids
    Douglas Borchman
    Department of Ophthalmology and Visual Science, University of Louisville, 301 E Muhammad Ali Blvd, Louisville, KY 40202, USA
    Chem Phys Lipids 147:87-102. 2007
    ..The results provide a foundation for future studies to assess possible differences with age and sex in tears from normal and dry eye subjects...
  27. ncbi request reprint Topical cyclosporine for treatment of ocular surface disease
    Gary N Foulks
    Kentucky Lion s Eye Center, Louisville, KY 40207, USA
    Int Ophthalmol Clin 46:105-22. 2006
  28. ncbi request reprint Ocular surface effects of thyroid disease
    Jason A Sokol
    Department of Ophthalmology and Visual Sciences, Kentucky Lions Eye Center, University of Louisville, Louisville, KY 40202, USA
    Ocul Surf 8:29-39. 2010
    ....
  29. ncbi request reprint The correlation between the tear film lipid layer and dry eye disease
    Gary N Foulks
    Department of Ophthalmology and Vision Science, University of Louisville, Louisville, KY, USA
    Surv Ophthalmol 52:369-74. 2007
    ..Thus, therapies targeted at replenishing or stabilizing the lipid layer are key to the treatment of dry eye, either as monotherapy or in conjunction with therapies designed to enhance aqueous production...
  30. doi request reprint Elevated immunoglobulin to tissue KLK11 in patients with Sjögren syndrome
    Jaafar El Annan
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY 40202, USA
    Cornea 32:e90-3. 2013
    ..In this study, we determine whether the production of antibodies against tissue KLK is specific for SS and whether the antibody can be used as a biomarker for the diagnosis in humans...
  31. ncbi request reprint MUC1 splice variants in human ocular surface tissues: possible differences between dry eye patients and normal controls
    Yoannis Imbert
    Department of Molecular, Cellular and Craniofacial Biology, School of Dentistry, University of Louisville, 501 S Preston St, Louisville, KY 40292, USA
    Exp Eye Res 83:493-501. 2006
    ....
  32. ncbi request reprint Acanthamoeba keratitis and contact lens wear: static or increasing problem?
    Gary N Foulks
    University of Louisville School of Medicine, Louisville, KY, USA
    Eye Contact Lens 33:412-4; discussion 424-5. 2007
    ..Strategies for prevention, including patient education, improved decontaminating agents, maintenance of water treatment standards, and possible immunization of subjects at risk, are needed...
  33. ncbi request reprint Phase III safety evaluation of cyclosporine 0.1% ophthalmic emulsion administered twice daily to dry eye disease patients for up to 3 years
    Laurie D Barber
    Department of Ophthalmology, University of Arkansas, Little Rock, Arkansas 72205, USA
    Ophthalmology 112:1790-4. 2005
    ..To evaluate cyclosporine 0.1% ophthalmic emulsion over a 1- to 3-year period in moderate to severe dry eye disease patients...
  34. ncbi request reprint Therapeutic contact lenses: the role of high-Dk lenses
    Gary N Foulks
    Department of Ophthalmology, University of Pittsburgh School of Medicine, 203 Lothrop Street, Pittsburgh, PA 15213, USA
    Ophthalmol Clin North Am 16:455-61. 2003
    ..Not all of the available lenses are FDA approved for therapeutic use, and such wear is an off-label use. The patient should be informed of the goal of therapy as well as the benefits and risks of therapeutic contact lenses...
  35. ncbi request reprint What is dry eye and what does it mean to the contact lens wearer?
    Gary N Foulks
    Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Eye Contact Lens 29:S96-100; discussion S115-8, S192-4. 2003
    ..To relate tear function to contact lens wear and review the problems dry eye causes with contact lens tolerance and performance...
  36. ncbi request reprint The evolving treatment of dry eye
    Gary N Foulks
    Eye and Ear Institute, Department of Ophthalmology, University of Pittsburgh School of Medicine, 203 Lothrop Street, Pittsburgh, PA 15213, USA
    Ophthalmol Clin North Am 16:29-35. 2003
    ..It has taken 20 years of investigation to reach this threshold. The next 3 years should see promising treatments approved for dry eye disease...
  37. ncbi request reprint Ocular surface morphogenesis and pathogenesis in health and disease
    Gary N Foulks
    Ocul Surf 6:1. 2008
  38. ncbi request reprint Changing trends in the definition and diagnosis of dry eyes
    Murat Dogru
    Am J Ophthalmol 140:507-8. 2005
  39. ncbi request reprint Removal of INTACS for myopia
    Thomas E Clinch
    University Ophthalmic Consultants of Washington, DC 20016, USA
    Ophthalmology 109:1441-6. 2002
    ..To evaluate the safety and efficacy of the removal of INTACS...
  40. ncbi request reprint Pathways, new visions, and old challenges
    Gary N Foulks
    Ocul Surf 6:103. 2008
  41. ncbi request reprint Different ways of looking at things
    Gary N Foulks
    Ocul Surf 6:60. 2008
  42. doi request reprint The changing times in dry eye research
    Kelly K Nichols
    Optom Vis Sci 85:613-4. 2008
  43. ncbi request reprint Development and validation of a short global dry eye symptom index
    Debra A Schaumberg
    Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts 02215, USA
    Ocul Surf 5:50-7. 2007
    ..The results are encouraging and suggest that further refinement and testing of the SANDE questionnaire in larger populations may result in a reliable questionnaire to detect change in irritative symptoms over time...