B L Foster
Affiliation: University of Washington
- The progressive ankylosis protein regulates cementum apposition and extracellular matrix compositionB L Foster
Department of Periodontics, University of Washington School of Dentistry, Seattle, Wash 98195, USA
Cells Tissues Organs 194:382-405. 2011..Studies here aimed to define the role of ANK in root and cementum by analyzing tooth development in Ank knock-out (KO) mice versus wild type...
- Regulation of cementoblast gene expression by inorganic phosphate in vitroB L Foster
Department of Periodontics, School of Dentistry, University of Washington, Seattle, WA, USA
Calcif Tissue Int 78:103-12. 2006..During formation, phosphate and pyrophosphate may be important regulators of cementoblast functions including maturation and regulation of matrix mineralization...
- Defining the roots of cementum formationT Popowics
Department of Oral Biology, University of Washington School of Dentistry, Seattle, Wash 98195, USA
Cells Tissues Organs 181:248-57. 2005..e. follicle cells, periodontal cells, and cementoblasts) and offer new directions to consider for clinical repair of periodontal defects...
- Structure and mechanical properties of Ank/Ank mutant mouse dental tissues--an animal model for studying periodontal regenerationH Fong
Materials Science and Engineering, University of Washington, Seattle, WA, USA
Arch Oral Biol 54:570-6. 2009..In conclusion, these data suggest that this animal model can be utilized for studies focused on defining mechanisms to promote cementum formation without loss of mechanical integrity...
- Ablation of systemic phosphate-regulating gene fibroblast growth factor 23 (Fgf23) compromises the dentoalveolar complexE Y Chu
Department of Periodontics, School of Dentistry, University of Washington, Seattle, Washington, USA
Anat Rec (Hoboken) 293:1214-26. 2010..Based on these results, we propose that FGF23 and (P(i)) homeostasis play a significant role in maintenance of the dentoalveolar complex...
- Aberrant cementum phenotype associated with the hypophosphatemic hyp mouseH Fong
Department of Materials Science and Engineering, University of Washington, Seattle, WA, USA
J Periodontol 80:1348-54. 2009..Here, we report a developmental study of tooth root formation in Hyp mouse molars, focusing on dentin and cementum...
- Wnt/β-catenin pathway regulates bone morphogenetic protein (BMP2)-mediated differentiation of dental follicle cellsK G Silvério
Institute for Stem Cells and Regenerative Medicine, University of Washington, School of Medicine, Seattle, WA, USA
J Periodontal Res 47:309-19. 2012....
- Cementum: a phosphate-sensitive tissueF H Nociti
Department of Periodontics Prevention Geriatrics, School of Dentistry, Rm 3310M Dental, University of Michigan, 1011 N University Avenue, Ann Arbor, MI 48109 1078, USA
J Dent Res 81:817-21. 2002..This information may prove valuable in attempts to design successful therapies for regenerating periodontal tissues...
- Phosphate regulates osteopontin gene transcriptionS Fatherazi
Department of Oral Biology, University of Washington, Seattle, WA 98195 7132, USA
J Dent Res 88:39-44. 2009..The results presented support a model demonstrating that inorganic phosphate regulates OPN gene transcription in cementoblasts through a pathway that requires a functional GR...
- Extracellular phosphate alters cementoblast gene expressionR B Rutherford
Department of Oral Biology, School of Dentistry, University of Washington, Box 357132, Seattle, WA 98195 7132, USA
J Dent Res 85:505-9. 2006..Analyses of significant hybridization signals indicated that 5 mM extracellular phosphate alters the expression of genes comprising several gene ontology (GO) groups, including transcription factor activity and Wnt signaling...
- Regenerating the periodontium: is there a magic formula?B L Foster
Department of Periodontics, School of Dentistry, University of Washington, Seattle, 98195, USA
Orthod Craniofac Res 8:285-91. 2005..Critical to improving the predictability of regenerative therapies is targeting studies toward enhancing our understanding of the cellular and molecular events required to restore periodontal tissues...
- Regulation of cementoblast function by P. gingivalis lipopolysaccharide via TLR2E Nemoto
Department of Periodontics, School of Dentistry, University of Washington, D322-Health Science Center Box 356365, Seattle, WA 98195-6365, USA
J Dent Res 85:733-8. 2006..These results suggest that cementoblasts participate in the recruitment of osteoclastic precursor cells by up-regulation of chemokines/cytokines...
- Cementoblast gene expression is regulated by Porphyromonas gingivalis lipopolysaccharide partially via toll-like receptor-4/MD-2F H Nociti
Department of Prosthodontics/Periodontics, Division of Periodontics, School of Dentistry at Piracicaba, University of Campinas, Brazil
J Dent Res 83:602-7. 2004..g., RANKL/OPG), thereby potentially affecting the inflammation-associated resorption of mineralized tissues...