Research Topics
| Charles N FordSummaryAffiliation: University of Wisconsin Country: USA Publications
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Detail Information
Publications
Paradigms and progress in vocal fold restorationCharles N Ford
Department of Surgery, Division of Otolaryngology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
Laryngoscope 118:1709-13. 2008....
Evaluation and management of laryngopharyngeal refluxCharles N Ford
Department of Surgery, Division of Otolaryngology, University of Wisconsin, Madison, USA
JAMA 294:1534-40. 2005..Laryngopharyngeal reflux (LPR) is a major cause of laryngeal inflammation and presents with a constellation of symptoms different from classic gastroesophageal reflux disease...
G. Paul Moore lecture: lessons in phonosurgeryCharles N Ford
Division of Otolaryngology, University of Wisconsin Hospital and Clinics, Madison, WI, USA
J Voice 18:534-44. 2004
Characterization of chronic vocal fold scarring in a rabbit modelBernard Rousseau
Department of Communicative Disorders, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
J Voice 18:116-24. 2004..Based on these results, a 6-month postoperative time frame is proposed for future studies of chronic vocal fold scarring using the rabbit animal model...
Prospective multi-arm evaluation of surgical treatments for vocal fold scar and pathologic sulcus vocalisNathan V Welham
Division of Otolaryngology, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison Wisconsin, USA
Laryngoscope 121:1252-60. 2011..The purpose of this study was to compare the clinical effectiveness of type I thyroplasty, injection laryngoplasty, and graft implantation for the treatment of vocal fold scar and pathologic sulcus vocalis...
Treatment of vocal fold scarring: rheological and histological measures of homologous collagen matrixKevin J Kriesel
Department of Surgery, University of Wisconsin-Madison, 53792-7375, USA
Ann Otol Rhinol Laryngol 111:884-9. 2002..This study demonstrates that HCM is an inert, relatively stable injectate that may serve well for medialization but does not appear to improve the dynamic properties of the lamina propria...
Regeneration of aged vocal folds with basic fibroblast growth factor in a rat model: a preliminary reportShigeru Hirano
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA
Ann Otol Rhinol Laryngol 114:304-8. 2005..A drug delivery system for bFGF also needs to be developed to maximize its effect in the future. The present study suggested at least a positive effect of bFGF in restoring the HA content in the aged vocal fold lamina propria...
Growth factor therapy for vocal fold scarring in a canine modelShigeru Hirano
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA
Ann Otol Rhinol Laryngol 113:777-85. 2004..From these data it is concluded that HGF has considerable potential in the treatment of vocal fold scarring...
Morphological and functional changes of human vocal fold fibroblasts with hepatocyte growth factorShigeru Hirano
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA
Ann Otol Rhinol Laryngol 112:1026-33. 2003..The increased HA and decreased collagen type I production from the FbRS suggest that HGF may be useful in the prevention or treatment of fibrotic vocal fold scarring...
Effect of growth factors on hyaluronan production by canine vocal fold fibroblastsShigeru Hirano
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin-Madison, Madison, Wisconsin 53792, USA
Ann Otol Rhinol Laryngol 112:617-24. 2003..The present studies have demonstrated positive effects of growth factors in stimulating HYA production. Further in vivo study is needed to clarify the usefulness of these growth factors in the management of vocal fold scarring...
Clinical evaluation of Parkinson's-related dysphoniaGregory K Sewall
University of Wisconsin Hospitals and Clinics, Madison, Wisconsin, USA
Laryngoscope 116:1740-4. 2006..Reduction of glottal gap with collagen improves MPT and subglottal PTP. The resulting gain of vocal efficiency may reduce vocal fatigue and provide a useful adjunct to voice therapy for PRD...
Fibronectin and adhesion molecules on canine scarred vocal foldsShigeru Hirano
Department of Surgery, University of Wisconsin Madison, 53792, USA
Laryngoscope 113:966-72. 2003..To examine the expressions of fibronectin and other adhesion molecules on the scarred vocal folds in a short- and long-term animal model...
Voice handicap evaluation of patients with pathologic sulcus vocalisNathan V Welham
Department of Surgery, Division of Otolaryngology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
Ann Otol Rhinol Laryngol 116:411-7. 2007..The purpose of this study was to characterize the psychosocial impact of dysphonia on patients with pathologic sulcus vocalis by use of the Voice Handicap Index (VHI)...
Age-related alterations in myosin heavy chain isoforms in rat intrinsic laryngeal musclesTatsutoshi Suzuki
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin, Madison, USA
Ann Otol Rhinol Laryngol 111:962-7. 2002..These findings suggest that aging may affect laryngeal adductory function by altering muscle fiber type composition to a slower-contracting isoform, in a manner similar to that observed with denervation...
Surgical management of sulcus vocalis and vocal fold scarringSeth H Dailey
Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine, University of Wisconsin Hospital and Clinics, K4/720, 600 Highland Avenue, Madison, WI 53792-7375, USA
Otolaryngol Clin North Am 39:23-42. 2006
A-P positioning of medialization thyroplasty in an excised larynx modelLukasz Czerwonka
Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
Laryngoscope 119:591-6. 2009..Posterior positioning of medialization thyroplasty provides the best acoustic and aerodynamic outcomes...
Use of lasers in laryngeal surgeryYan Yan
Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
J Voice 24:102-9. 2010..Recent applications of lasers to treat benign laryngeal lesions and severe laryngomalacia demonstrate that additional research must be conducted to realize the full potential of this surgical tool...
Tracking outcomes after phonosurgery for sulcus vocalis: a case reportNathan V Welham
Department of Surgery, Division of Otolaryngology, University of Wisconsin Madison, Madison, Wisconsin, USA
J Voice 17:571-8. 2003..This report reinforces the value of following patients until complete outcome stability...
Differentiating between adductor and abductor spasmodic dysphonia using airflow interruptionMatthew R Hoffman
Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA
Laryngoscope 119:1851-5. 2009..To measure the laryngeal resistance (R(L)), subglottal pressure (P(s)), and mean flow rate (MFR) of adductor (ADSD) and abductor (ABSD) spasmodic dysphonia patients using the airflow interrupter...
Hepatocyte growth factor and its receptor c-met in rat and rabbit vocal foldsShigeru Hirano
Department of Surgery, University of Wisconsin-Madison, 53792, USA
Ann Otol Rhinol Laryngol 111:661-6. 2002..The implication of these findings is that HGF is involved in wound healing of the vocal fold, and may provide an alternative approach in preventing and treating vocal fold scarring...
Nonlinear dynamics of phonations in excised larynx experimentsJack J Jiang
Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin Medical School, Madison, Wisconsin 53792 7375, USA
J Acoust Soc Am 114:2198-205. 2003..These findings might potentially assist investigators in understanding rough phonations and developing clinically valuable methodologies for the diagnosis of voice disorders...
Genotypic and phenotypic expression of vocal fold polyps and Reinke's edema: a preliminary studySusan L Thibeault
Department of Surgery, University of Wisconsin-Madison, USA
Ann Otol Rhinol Laryngol 111:302-9. 2002..The study also gives clues as to the proteins responsible for the phenotype...
Laryngeal-respiratory kinematics are impaired in aged ratsTatsutoshi Suzuki
Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin Medical School, Madison, USA
Ann Otol Rhinol Laryngol 111:684-9. 2002..Because of the serious and pervasive nature of dysphagia and communicative impairments in the elderly, research that specifically examines the manifestations and causes of these impairments is of great importance...
Histologic and rheologic characterization of vocal fold scarringSusan L Thibeault
Department of Surgery, University of Utah, Primary Children's Hospital, Salt Lake City 84113, USA
J Voice 16:96-104. 2002..This animal model should allow for systematic future investigations of vocal fold scarring and its treatment...
Cidofovir efficacy in recurrent respiratory papillomatosis: a randomized, double-blind, placebo-controlled studyJ Scott McMurray
Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
Ann Otol Rhinol Laryngol 117:477-83. 2008..Although results of case series suggest that cidofovir may decrease the frequency and rapidity of papilloma regrowth, no blinded placebo-controlled studies have demonstrated efficacy...
Glottal configuration, acoustic, and aerodynamic changes induced by variation in suture direction in arytenoid adduction proceduresKatsuhide Inagi
Department of Otolaryngology-Head and Neck Surgery, Kitasato Institute Medical Center Hospital, Saitama, Japan
Ann Otol Rhinol Laryngol 111:861-70. 2002..Changes in suture direction and force of pull also affected acoustic and aerodynamic measures of induced voice. Therefore, voice outcomes can be optimized with arytenoid adduction if the vocal fold plane is accurately adjusted...
Therapeutic potential of growth factors for aging voiceShigeru Hirano
From the Department of Bronchoesophagology, Kyoto National Hospital, Kyoto, Japan
Laryngoscope 114:2161-7. 2004..CONCLUSION: The present results suggest that growth factors, especially basic fibroblast growth factor, may have therapeutic potential in restoration of aged vocal fold...
Prevention of vocal fold scarring by topical injection of hepatocyte growth factor in a rabbit modelShigeru Hirano
Department of Bronchoesophagology, Kyoto National Hospital, Kyoto, Japan
Laryngoscope 114:548-56. 2004..The present study aimed to demonstrate the effects of HGF on vocal fold scarring in an in vivo rabbit model...
Influence of vocal fold scarring on phonation: predictions from a finite element modelDavid A Berry
Laryngeal Dynamics Laboratory, Division of Head and Neck Surgery, David Geffen School of Medicine, The University of California, Los Angeles, Los Angeles, California, USA
Ann Otol Rhinol Laryngol 114:847-52. 2005....
