Gregg C Fonarow

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF)
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, University of California, Los Angeles, Medical Center, Los Angeles, CA, USA
    Am J Cardiol 104:107-15. 2009
  2. doi request reprint Improving door-to-needle times in acute ischemic stroke: the design and rationale for the American Heart Association/American Stroke Association's Target: Stroke initiative
    Gregg C Fonarow
    University of California, Los Angeles, Department of Neurology, Ahmanson UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, 10833 LeConte Avenue, Room 47 123 CHS, Los Angeles, CA 90095 1679, USA
    Stroke 42:2983-9. 2011
  3. pmc Trends in incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction in the United States
    Dhaval Kolte
    Department of Medicine, New York Medical College, Valhalla, NY
    J Am Heart Assoc 3:e000590. 2014
  4. pmc Incremental Reduction in Risk of Death Associated With Use of Guideline-Recommended Therapies in Patients With Heart Failure: A Nested Case-Control Analysis of IMPROVE HF
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, Los Angeles, CA G C F
    J Am Heart Assoc 1:16-26. 2012
  5. pmc Relationship of national institutes of health stroke scale to 30-day mortality in medicare beneficiaries with acute ischemic stroke
    Gregg C Fonarow
    Division of Cardiology, University of California, Los Angeles, CA G C F
    J Am Heart Assoc 1:42-50. 2012
  6. pmc Patterns, predictors, variations, and temporal trends in emergency medical service hospital prenotification for acute ischemic stroke
    Cheryl B Lin
    Duke National University of Singapore, Singapore C B L
    J Am Heart Assoc 1:e002345. 2012
  7. pmc Use of hydralazine-isosorbide dinitrate combination in African American and other race/ethnic group patients with heart failure and reduced left ventricular ejection fraction
    Harsh B Golwala
    Oklahoma University Health Science Center, VA Medical Center, Oklahoma City, OK
    J Am Heart Assoc 2:e000214. 2013
  8. pmc Comparison of performance achievement award recognition with primary stroke center certification for acute ischemic stroke care
    Gregg C Fonarow
    Division of Cardiology, University of California, Los Angeles, CA
    J Am Heart Assoc 2:e000451. 2013
  9. doi request reprint Comparison of 30-day mortality models for profiling hospital performance in acute ischemic stroke with vs without adjustment for stroke severity
    Gregg C Fonarow
    Division of Cardiology, University of California, Los Angeles, USA
    JAMA 308:257-64. 2012
  10. ncbi request reprint Improving the use of evidence-based heart failure therapies in the outpatient setting: the IMPROVE HF performance improvement registry
    Gregg C Fonarow
    Department of Medicine, Ahmanson UCLA Cardiomyopathy Center, Los Angeles, CA 90095 1679, USA
    Am Heart J 154:12-38. 2007

Research Grants

Collaborators

Detail Information

Publications130 found, 100 shown here

  1. ncbi request reprint Age- and gender-related differences in quality of care and outcomes of patients hospitalized with heart failure (from OPTIMIZE-HF)
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, University of California, Los Angeles, Medical Center, Los Angeles, CA, USA
    Am J Cardiol 104:107-15. 2009
    ..Older patients with HF were less likely to receive guideline-recommended therapies and remained at greater risk of adverse outcomes...
  2. doi request reprint Improving door-to-needle times in acute ischemic stroke: the design and rationale for the American Heart Association/American Stroke Association's Target: Stroke initiative
    Gregg C Fonarow
    University of California, Los Angeles, Department of Neurology, Ahmanson UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, 10833 LeConte Avenue, Room 47 123 CHS, Los Angeles, CA 90095 1679, USA
    Stroke 42:2983-9. 2011
    ....
  3. pmc Trends in incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction in the United States
    Dhaval Kolte
    Department of Medicine, New York Medical College, Valhalla, NY
    J Am Heart Assoc 3:e000590. 2014
    ..Limited information is available on the contemporary and potentially changing trends in the incidence, management, and outcomes of cardiogenic shock complicating ST-elevation myocardial infarction (STEMI)...
  4. pmc Incremental Reduction in Risk of Death Associated With Use of Guideline-Recommended Therapies in Patients With Heart Failure: A Nested Case-Control Analysis of IMPROVE HF
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, Los Angeles, CA G C F
    J Am Heart Assoc 1:16-26. 2012
    ..We aimed to evaluate the individual and incremental benefits of guideline-recommended HF therapies associated with 24-month survival...
  5. pmc Relationship of national institutes of health stroke scale to 30-day mortality in medicare beneficiaries with acute ischemic stroke
    Gregg C Fonarow
    Division of Cardiology, University of California, Los Angeles, CA G C F
    J Am Heart Assoc 1:42-50. 2012
    ..However, the relationship, optimal categorization, and risk discrimination with the NIHSS for predicting 30-day mortality among Medicare beneficiaries with acute ischemic stroke has not been well studied...
  6. pmc Patterns, predictors, variations, and temporal trends in emergency medical service hospital prenotification for acute ischemic stroke
    Cheryl B Lin
    Duke National University of Singapore, Singapore C B L
    J Am Heart Assoc 1:e002345. 2012
    ..These results support the need for enhanced implementation of stroke systems of care. (J Am Heart Assoc. 2012;1:e002345 doi: 10.1161/JAHA.112.002345.)...
  7. pmc Use of hydralazine-isosorbide dinitrate combination in African American and other race/ethnic group patients with heart failure and reduced left ventricular ejection fraction
    Harsh B Golwala
    Oklahoma University Health Science Center, VA Medical Center, Oklahoma City, OK
    J Am Heart Assoc 2:e000214. 2013
    ....
  8. pmc Comparison of performance achievement award recognition with primary stroke center certification for acute ischemic stroke care
    Gregg C Fonarow
    Division of Cardiology, University of California, Los Angeles, CA
    J Am Heart Assoc 2:e000451. 2013
    ....
  9. doi request reprint Comparison of 30-day mortality models for profiling hospital performance in acute ischemic stroke with vs without adjustment for stroke severity
    Gregg C Fonarow
    Division of Cardiology, University of California, Los Angeles, USA
    JAMA 308:257-64. 2012
    ....
  10. ncbi request reprint Improving the use of evidence-based heart failure therapies in the outpatient setting: the IMPROVE HF performance improvement registry
    Gregg C Fonarow
    Department of Medicine, Ahmanson UCLA Cardiomyopathy Center, Los Angeles, CA 90095 1679, USA
    Am Heart J 154:12-38. 2007
    ..Deidentified clinical data from the medical records of a planned 43,000 patients from 160 US cardiology practices will be included in this study...
  11. ncbi request reprint Influence of a performance-improvement initiative on quality of care for patients hospitalized with heart failure: results of the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure (OPTIMIZE-HF)
    Gregg C Fonarow
    Department of Medicine, University of California Los Angeles Medical Center, 10833 LeConte Ave, Room 47 123 CHS, Los Angeles, CA 90095 1679, USA
    Arch Intern Med 167:1493-502. 2007
    ..We sought to evaluate the effect of a national hospital-based initiative on quality of care in patients hospitalized with HF...
  12. ncbi request reprint Characteristics, treatments, and outcomes of patients with preserved systolic function hospitalized for heart failure: a report from the OPTIMIZE-HF Registry
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Department of Medicine, UCLA Medical Center, Los Angeles, California 90095 1679, USA
    J Am Coll Cardiol 50:768-77. 2007
    ..We sought to evaluate the characteristics, treatments, and outcomes of patients with preserved and reduced systolic function heart failure (HF)...
  13. ncbi request reprint Effects of carvedilol early after myocardial infarction: analysis of the first 30 days in Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN)
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1679, USA
    Am Heart J 154:637-44. 2007
    ..This analysis sought to assess the impact of carvedilol within the first 30 days of randomization...
  14. ncbi request reprint Performance measures for patients hospitalized with heart failure: are they predictive of clinical outcomes?
    Gregg C Fonarow
    University of California Los Angeles Medical Center, Los Angeles, CA 90095 1679, USA
    Congest Heart Fail 13:342-6. 2007
  15. doi request reprint Usefulness of B-type natriuretic peptide and cardiac troponin levels to predict in-hospital mortality from ADHERE
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, University of California, Los Angeles Medical Center, Los Angeles, California, USA
    Am J Cardiol 101:231-7. 2008
    ..In conclusion, a multimarker strategy for the assessment of patients hospitalized with HF adds incremental prognostic information...
  16. doi request reprint Epidemiology and risk stratification in acute heart failure
    Gregg C Fonarow
    Ahmanson University of California Los Angeles Cardiomyopathy Center, University of California Los Angeles, Los Angeles, CA, USA
    Am Heart J 155:200-7. 2008
    ..This article will discuss the epidemiology, mortality predictors, and risk stratification models for patients hospitalized with acute HF and provide a perspective on the value of integrating these tools in clinical practice...
  17. ncbi request reprint Temporal trends in clinical characteristics, treatments, and outcomes for heart failure hospitalizations, 2002 to 2004: findings from Acute Decompensated Heart Failure National Registry (ADHERE)
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Los Angeles, CA 90095, USA
    Am Heart J 153:1021-8. 2007
    ..The purpose of this study was to assess temporal trends in clinical characteristics, treatments, quality indicators, and outcomes for heart failure (HF) hospitalizations...
  18. ncbi request reprint Admission B-type natriuretic peptide levels and in-hospital mortality in acute decompensated heart failure
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, University of California, Los Angeles Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 49:1943-50. 2007
    ..This study was designed to determine whether admission B-type natriuretic peptide (BNP) levels are predictive of in-hospital mortality in acute decompensated heart failure (HF)...
  19. ncbi request reprint Association between performance measures and clinical outcomes for patients hospitalized with heart failure
    Gregg C Fonarow
    University of California Los Angeles Medical Center, Los Angeles, CA 90095 1679, USA
    JAMA 297:61-70. 2007
    ..However, this link remains largely untested...
  20. ncbi request reprint Carvedilol use at discharge in patients hospitalized for heart failure is associated with improved survival: an analysis from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF)
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, Los Angeles, CA 90095 1679, USA
    Am Heart J 153:82.e1-11. 2007
    ....
  21. ncbi request reprint An obesity paradox in acute heart failure: analysis of body mass index and inhospital mortality for 108,927 patients in the Acute Decompensated Heart Failure National Registry
    Gregg C Fonarow
    Ahmanson University of California Los Angeles Cardiomyopathy Center, University of California Los Angeles Medical Center, Los Angeles, CA 90095, USA
    Am Heart J 153:74-81. 2007
    ..The aim of this study was to determine whether BMI influences the mortality risk in acute decompensated HF, a subject not previously studied...
  22. ncbi request reprint Profile of carvedilol controlled-release: a new once-daily formulation of carvedilol
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, 10833 LeConte Avenue, Los Angeles, CA 90095 1679, USA
    Expert Opin Pharmacother 7:2533-46. 2006
    ....
  23. ncbi request reprint The confounding issue of comorbid renal insufficiency
    Gregg C Fonarow
    Division of Cardiology, David Geffen School of Medicine at UCLA, University of California Los Angeles, Los Angeles, California, USA
    Am J Med 119:S17-25. 2006
    ..Despite this, few evidence-based data are available to guide management decisions, indicating a compelling need for additional studies in this patient population...
  24. doi request reprint Comprehensive adrenergic blockade post myocardial infarction left ventricular dysfunction
    Gregg C Fonarow
    Geffen School of Medicine at UCLA, UCLA Medical Center, Los Angeles, CA, USA
    Cardiol Clin 26:79-89, vii. 2008
    ....
  25. ncbi request reprint Hospital protocols and evidence-based therapies: the importance of integrating aldosterone blockade into the management of patients with post-acute myocardial infarction heart failure
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, The David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1679, USA
    Clin Cardiol 29:4-8. 2006
    ....
  26. doi request reprint The role of statins in heart failure. Preface
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, 10833 LeConte Avenue, Room 47 123 CHS, Los Angeles, CA 90095 1679, USA
    Heart Fail Clin 4:xiii-xiv. 2008
  27. doi request reprint Factors identified as precipitating hospital admissions for heart failure and clinical outcomes: findings from OPTIMIZE-HF
    Gregg C Fonarow
    Department of Medicine, UCLA University of California, Los Angeles Medical Center, Los Angeles, CA 90095 1679, USA
    Arch Intern Med 168:847-54. 2008
    ..This study evaluated the association between precipitating factors identified at the time of HF hospital admission and subsequent clinical outcomes...
  28. ncbi request reprint Improving quality of care and outcomes for heart failure. -Role of registries-
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, University of California Los Angeles, CA, USA
    Circ J 75:1783-90. 2011
    ....
  29. doi request reprint Potential impact of optimal implementation of evidence-based heart failure therapies on mortality
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, Los Angeles, CA 90095 1679, USA
    Am Heart J 161:1024-30.e3. 2011
    ..To date, empiric estimation of the potential benefits that could be gained from eliminating these existing treatment gaps with optimal implementation has not been quantified...
  30. doi request reprint Associations between outpatient heart failure process-of-care measures and mortality
    Gregg C Fonarow
    Department of Medicine, Ahmanson UCLA Cardiomyopathy Center, Los Angeles, CA 90095 1679, USA
    Circulation 123:1601-10. 2011
    ..However, this association has not been evaluated for current and emerging outpatient HF measures...
  31. doi request reprint Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes associated with door-to-needle times within 60 minutes
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Ronald Reagan UCLA Medical Center, 10833 LeConte Ave, Los Angeles, CA 90095 1679, USA
    Circulation 123:750-8. 2011
    ..The benefits of intravenous tissue-type plasminogen activator (tPA) in acute ischemic stroke are time dependent, and guidelines recommend an arrival to treatment initiation (door-to-needle) time of ≤60 minutes...
  32. doi request reprint Improving evidence-based care for heart failure in outpatient cardiology practices: primary results of the Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting (IMPROVE HF)
    Gregg C Fonarow
    Department of Medicine, Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, Los Angeles, CA 90095 1679, USA
    Circulation 122:585-96. 2010
    ....
  33. doi request reprint Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-stroke
    Gregg C Fonarow
    University of California, Los Angeles, USA
    Circ Cardiovasc Qual Outcomes 3:291-302. 2010
    ....
  34. doi request reprint Age-related differences in characteristics, performance measures, treatment trends, and outcomes in patients with ischemic stroke
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, 10833 LeConte Ave, Room 47 123 CHS, Los Angeles, CA 90095 1679, USA
    Circulation 121:879-91. 2010
    ..We sought to examine age-related differences in characteristics, performance measures, temporal trends, and early clinical outcomes for acute ischemic stroke in a large contemporary cohort...
  35. doi request reprint Heart failure care in the outpatient cardiology practice setting: findings from IMPROVE HF
    Gregg C Fonarow
    Department of Medicine, Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, Los Angeles, CA 90095 1679, USA
    Circ Heart Fail 1:98-106. 2008
    ..IMPROVE HF is a prospective cohort study designed to characterize current management of patients with chronic HF and ejection fraction < or =35% in a national registry of 167 US outpatient cardiology practices...
  36. doi request reprint Sudden cardiac arrest prevention pathways and tools
    Gregg C Fonarow
    Department of Medicine, Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, Los Angeles, California 90095 1679, USA
    Crit Pathw Cardiol 8:79-87. 2009
    ..By facilitating best-care practices, the program aims to assist physicians and other health care providers in a meaningful way to improve cardiovascular care and optimize clinical outcomes...
  37. doi request reprint Role of carvedilol controlled-release in cardiovascular disease
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, 10833 LeConte Avenue, Los Angeles, CA 90095 1679, USA
    Expert Rev Cardiovasc Ther 7:483-98. 2009
    ..The convenience of once-daily dosing is expected to contribute to patient adherence, thereby potentially improving long-term clinical outcomes...
  38. doi request reprint Hospital-level variation in mortality and rehospitalization for medicare beneficiaries with acute ischemic stroke
    Gregg C Fonarow
    Division of Cardiology, University of California, Los Angeles, CA, USA
    Stroke 42:159-66. 2011
    ..However, little is known regarding contemporary ischemic stroke mortality and rehospitalization rates for Medicare beneficiaries and how they vary by hospital...
  39. doi request reprint Trends in the use of lipid-lowering medications at discharge in patients with acute myocardial infarction: 1998 to 2006
    Gregg C Fonarow
    UCLA Division of Cardiology, Ahmanson UCLA Cardiomyopathy Center, Los Angeles, CA 90095 1679, USA
    Am Heart J 157:185-194.e2. 2009
    ..The objective of this study is to determine trends in the use of lipid-lowering medications at discharge for AMI...
  40. doi request reprint Dosing of beta-blocker therapy before, during, and after hospitalization for heart failure (from Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure)
    Gregg C Fonarow
    Department of Medicine, UCLA Medical Center, Los Angeles, CA, USA
    Am J Cardiol 102:1524-9. 2008
    ..In the first 60 to 90 days after hospital discharge, little up-titration in beta-blocker dosing occurs. Further efforts are needed to help understand and overcome this beta-blocker titration gap...
  41. doi request reprint Influence of beta-blocker continuation or withdrawal on outcomes in patients hospitalized with heart failure: findings from the OPTIMIZE-HF program
    Gregg C Fonarow
    Department of Medicine, University of California Los Angeles Medical Center, Los Angeles, California 90095 1679, USA
    J Am Coll Cardiol 52:190-9. 2008
    ..This study ascertains the relationship between continuation or withdrawal of beta-blocker therapy and clinical outcomes in patients hospitalized with systolic heart failure (HF)...
  42. ncbi request reprint In-hospital initiation of statin therapy in acute coronary syndromes: maximizing the early and long-term benefits
    Gregg C Fonarow
    Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1679, USA
    Chest 128:3641-51. 2005
    ..Every effort should be made to ensure all eligible patients with ACS are initiated and maintained on statin therapy...
  43. ncbi request reprint In-hospital initiation of statin therapy in patients with acute coronary events
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, UCLA School of Medicine, 47 123 CHS, 10833 LeConte Avenue, Los Angeles, CA 90095 1679, USA
    Curr Atheroscler Rep 5:394-402. 2003
  44. ncbi request reprint Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortality
    Gregg C Fonarow
    The Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, Los Angeles, California, USA
    Am J Cardiol 96:611-6. 2005
    ..0001). In conclusion, the use of statin therapy within the first 24 hours of hospitalization for AMI is associated with a significantly lower rate of early complications and in-hospital mortality...
  45. ncbi request reprint An approach to heart failure and diabetes mellitus
    Gregg C Fonarow
    Division of Cardiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA
    Am J Cardiol 96:47E-52E. 2005
    ..Furthermore, every effort should be made to ensure that eligible patients are treated with these evidence-based, guideline-recommended, life-prolonging therapies...
  46. ncbi request reprint When to initiate beta-blockers in heart failure: is it ever too early?
    Gregg C Fonarow
    Division of Cardiology, The David Geffen School of Medicine at UCLA, 10833 LeConte Avenue, Room 47 123 CHS, Los Angeles, CA 90095, USA
    Curr Heart Fail Rep 2:94-9. 2005
    ....
  47. ncbi request reprint Effective strategies for long-term statin use
    Gregg C Fonarow
    University of California, Los Angeles, Preventative Cardiology Program, Division of Cardiology, University of California, Los Angeles, California 90095 1679, USA
    Am J Cardiol 92:27i-34i. 2003
    ..Optimal use of statins and other cardioprotective medications in high-risk patients could save >83000 lives per year in the United States...
  48. ncbi request reprint Importance of in-hospital initiation of evidence-based medical therapies for heart failure: taking advantage of the teachable moment
    Gregg C Fonorow
    Ahmanson UCLA Cardiomyopathy Center, The David Geffen School of Medicine at UCLA, 10833 LeConte Avenue, Los Angeles, CA 90095, USA
    Congest Heart Fail 11:153-4. 2005
  49. ncbi request reprint Treating to goal: new strategies for initiating and optimizing lipid-lowering therapy in patients with atherosclerosis
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, Los Angeles, CA 90095 1679, USA
    Vasc Med 7:187-94. 2002
    ....
  50. ncbi request reprint Aggressive treatment of atherosclerosis: the time is now
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Cardiology Fellowship Training Program, UCLA Preventative Cardiology Program, Division of Cardiology, UCLA Division of Cardiology 90095, USA
    Cleve Clin J Med 70:431-4, 437-8, 440. 2003
    ..In those hospitalized with a cardiovascular event, a statin should be started in the hospital, regardless of lipid levels. Patients with diabetes should be treated as if they have preexisting cardiovascular disease...
  51. ncbi request reprint Practical considerations of beta-blockade in the management of the post-myocardial infarction patient
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, The David Geffen School of Medicine, UCLA, 90095 1679, USA
    Am Heart J 149:984-93. 2005
    ..This paper will discuss the background of beta-blocker use for the treatment of AMI, discuss the rationale for choosing specific agents, and present protocols for initiating or switching to evidence-based therapies...
  52. ncbi request reprint Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, University of California, Los Angeles Medical Center, Los Angeles, CA 90095, USA
    JAMA 293:572-80. 2005
    ..Estimation of mortality risk in patients hospitalized with acute decompensated heart failure (ADHF) may help clinicians guide care...
  53. ncbi request reprint Importance of in-hospital initiation of evidence-based medical therapies for heart failure-a review
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, The David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1679, USA
    Am J Cardiol 94:1155-60. 2004
    ....
  54. ncbi request reprint Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients with Heart Failure (OPTIMIZE-HF): rationale and design
    Gregg C Fonarow
    Department of Medicine, UCLA Medical Center, Los Angeles, Calif, USA
    Am Heart J 148:43-51. 2004
    ..The ultimate aim of this program is to improve the standard of HF care in the hospital and outpatient settings and increase the use of evidence-based therapeutic strategies to save lives...
  55. ncbi request reprint Improved survival in patients with nonischemic advanced heart failure and syncope treated with an implantable cardioverter-defibrillator
    G C Fonarow
    The Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, UCLA School of Medicine, Los Angeles, California 90095 1679, USA
    Am J Cardiol 85:981-5. 2000
    ..9% with ICD therapy and 66.9% with conventional therapy (p = 0.04). Thus, in patients with nonischemic cardiomyopathy and syncope, therapy with an ICD is associated with a reduction in sudden death and an improvement in overall survival...
  56. ncbi request reprint Role of in-hospital initiation of carvedilol to improve treatment rates and clinical outcomes
    Gregg C Fonarow
    Ahmanson University of California Los Angeles Cardiomyopathy Center, Division of Cardiology, University of California Los Angeles, Los Angeles, California 90095, USA
    Am J Cardiol 93:77B-81B. 2004
    ....
  57. ncbi request reprint How old is too old for heart transplantation?
    G C Fonarow
    Division of Cardiology, University of California at Los Angeles School of Medicine, 90095 1679, USA
    Curr Opin Cardiol 15:97-103. 2000
    ..This review presents a current perspective on outcomes after heart transplantation in older recipients, use of older donor hearts, and the matching of donor and recipient risk...
  58. ncbi request reprint Use of lipid-lowering medications at discharge in patients with acute myocardial infarction: data from the National Registry of Myocardial Infarction 3
    G C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, Los Angeles, CA 90095 1679, USA
    Circulation 103:38-44. 2001
    ..The present study aimed to assess use of lipid-lowering medication at discharge in a current national sample of patients hospitalized with acute myocardial infarction and to evaluate factors associated with prescribing patterns...
  59. ncbi request reprint Approach to the management of diabetic patients with heart failure: role of thiazolidinediones
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, Los Angeles, Calif 90095 1679, USA
    Am Heart J 148:551-8. 2004
    ..Prospective clinical trials are currently under way to further define the cardiovascular safety and efficacy of TZDs in diabetic patients with heart failure...
  60. ncbi request reprint In-hospital initiation of cardiovascular protective medications for patients undergoing percutaneous coronary intervention: taking advantage of the teachable moment
    Gregg C Fonarow
    UCLA Preventative Cardiology Program, UCLA Division of Cardiology, Los Angeles, CA 90095 1679, USA
    J Invasive Cardiol 15:646-52. 2003
    ....
  61. ncbi request reprint Improved treatment of coronary heart disease by implementation of a Cardiac Hospitalization Atherosclerosis Management Program (CHAMP)
    G C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, Department of Medicine, Los Angeles, California, USA
    Am J Cardiol 87:819-22. 2001
    ....
  62. ncbi request reprint Adherence to heart failure quality-of-care indicators in US hospitals: analysis of the ADHERE Registry
    Gregg C Fonarow
    Division of Cardiology, Ahmanson UCLA Cardiomyopathy Center, The David Geffen School of Medicine at University of California, Los Angeles 90095, USA
    Arch Intern Med 165:1469-77. 2005
    ..Quality-of-care indicators have been developed for patients hospitalized with heart failure. However, little is known about current rates of conformity with these indicators or their variability across hospitals...
  63. ncbi request reprint Statin therapy after acute myocardial infarction: are we adequately treating high-risk patients?
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, 47 123 CHS, 10833 LeConte Avenue, Los Angeles, CA 90095 1679, USA
    Curr Atheroscler Rep 4:99-106. 2002
    ....
  64. ncbi request reprint The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries
    Andrew P Ambrosy
    Department of Medicine, Stanford University School of Medicine, Palo Alto, California
    J Am Coll Cardiol 63:1123-33. 2014
    ..Moreover, based on the lessons learned, they also propose a roadmap for the design and conduct of future HHF registries...
  65. doi request reprint Reperfusion strategies and quality of care in 5339 patients age 80 years or older presenting with ST-elevation myocardial infarction: analysis from get with the guidelines-coronary artery disease
    Hector M Medina
    Department of Medicine, Montefiore Medical Center, Division of Cardiology, Albert Einstein College of Medicine, Bronx, New York, USA
    Clin Cardiol 35:632-40. 2012
    ..The aim of this study was to determine current reperfusion trends, medical treatment, and in-hospital mortality during STEMI in older adults...
  66. doi request reprint Comparison of medical therapy dosing in outpatients cared for in cardiology practices with heart failure and reduced ejection fraction with and without device therapy: report from IMPROVE HF
    J Thomas Heywood
    Division of Cardiology, Scripps Clinic Torrey Pines, La Jolla, Calif 92037, USA
    Circ Heart Fail 3:596-605. 2010
    ..Few data exist to characterize the delivery of evidence-based medical therapy for outpatients with heart failure who have received implantable cardioverter-defibrillators or cardiac resynchronization therapy (CRT) for systolic dysfunction...
  67. ncbi request reprint Systolic blood pressure at admission, clinical characteristics, and outcomes in patients hospitalized with acute heart failure
    Mihai Gheorghiade
    Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, Ill, USA
    JAMA 296:2217-26. 2006
    ..The association between systolic blood pressure (SBP) at admission, clinical characteristics, and outcomes in patients hospitalized for heart failure who have reduced or relatively preserved systolic function has not been well studied...
  68. ncbi request reprint Guideline adherence after ST-segment elevation versus non-ST segment elevation myocardial infarction
    Keith A Somma
    Division of Cardiovascular Medicine, Keck School of Medicine, University of Southern California, 1510 San Pablo St, Los Angeles, CA 90033, USA
    Circ Cardiovasc Qual Outcomes 5:654-61. 2012
    ..Clinical guidelines recommend similar medical therapy for patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation MI (NSTEMI)...
  69. doi request reprint Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke
    Jeffrey L Saver
    Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    JAMA 309:2480-8. 2013
    ..However, modest sample sizes have limited characterization of the extent to which onset to treatment (OTT) time influences outcome; and the generalizability of findings to clinical practice is uncertain...
  70. doi request reprint Influence of renal function on the use of guideline-recommended therapies for patients with heart failure
    J Thomas Heywood
    Scripps Clinic, La Jolla, CA, USA
    Am J Cardiol 105:1140-6. 2010
    ....
  71. ncbi request reprint Prospective evaluation of beta-blocker use at the time of hospital discharge as a heart failure performance measure: results from OPTIMIZE-HF
    Gregg C Fonarow
    Department of Medicine, University of California Los Angeles Medical Center, Los Angeles, California 90095 1679, USA
    J Card Fail 13:722-31. 2007
    ..The objective of this study was to prospectively evaluate beta-blocker use at hospital discharge as an indicator of quality of care and outcomes in patients with heart failure (HF)...
  72. ncbi request reprint Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry
    Mihai Gheorghiade
    Division of Cardiology, Feinberg School of Medicine, Northwestern University, Galter 10 240, 201 E Huron Street, Chicago, IL 60611, USA
    Eur Heart J 28:980-8. 2007
    ..The predictive value of hyponatraemia has not been evaluated in unselected patients hospitalized with heart failure...
  73. doi request reprint Cyclooxygenase products sensitize muscle mechanoreceptors in humans with heart failure
    Holly R Middlekauff
    Dept of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Am J Physiol Heart Circ Physiol 294:H1956-62. 2008
    ....
  74. ncbi request reprint Prevention of heart failure
    Tamara B Horwich
    Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, 47 123 CHS, 10833 Le Conte Avenue, Los Angeles, CA 90095 1679, USA
    Curr Cardiol Rep 4:194-9. 2002
    ....
  75. ncbi request reprint Low serum total cholesterol is associated with marked increase in mortality in advanced heart failure
    Tamara B Horwich
    UCLA Department of Medicine, Los Angeles, California, USA
    J Card Fail 8:216-24. 2002
    ..Although hypercholesterolemia is a well-defined risk factor for morbidity and mortality in coronary artery disease, the relationship between cholesterol and heart failure (HF) has rarely been investigated...
  76. ncbi request reprint A practical approach to reducing cardiovascular risk factors
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Preventive Cardiology Program, UCLA Division of Cardiology, Los Angeles, California, USA
    Rev Cardiovasc Med 8:S25-36. 2007
    ..This article discusses the current guidelines and addresses ways to increase implementation of evidence-based, guideline-recommended treatment by healthcare providers caring for at-risk patients...
  77. ncbi request reprint Total cholesterol levels and mortality risk in nonischemic systolic heart failure
    Nasim Afsarmanesh
    Ahmanson UCLA Cardiomyopathy Center, University of California, Los Angeles, Los Angeles, CA, USA
    Am Heart J 152:1077-83. 2006
    ..Prior studies have demonstrated that low serum total cholesterol (TC) is associated with increased mortality in heart failure (HF); however, this association has not been consistently observed in HF of nonischemic etiology...
  78. ncbi request reprint How well are chronic heart failure patients being managed?
    Gregg C Fonarow
    Division of Cardiology, University of California Los Angeles UCLA David Geffen School of Medicine, and Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, Los Angeles, California, USA
    Rev Cardiovasc Med 7:S3-11. 2006
    ....
  79. ncbi request reprint Acute decompensated heart failure: challenges and opportunities
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, Los Angeles, California, USA
    Rev Cardiovasc Med 8:S3-12. 2007
    ..Ongoing clinical trials are intended to provide data that will better define the benefits and risks of therapies for ADHF...
  80. ncbi request reprint Cardiac troponin I is associated with impaired hemodynamics, progressive left ventricular dysfunction, and increased mortality rates in advanced heart failure
    Tamara B Horwich
    Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, 47 123 CHS, 10833 Le Conte Ave, Los Angeles, Calif 90095 1679, USA
    Circulation 108:833-8. 2003
    ..Small studies report that cTnI is elevated in severe heart failure (HF) and may predict adverse outcomes...
  81. ncbi request reprint The management of the diabetic patient with prior cardiovascular events
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Rev Cardiovasc Med 4:S38-49. 2003
    ..Optimal glycemic control therapy for patients with heart failure has not been well-defined, and there is an urgent need for randomized clinical trials to determine optimal treatment...
  82. ncbi request reprint Gender differences in in-hospital management and outcomes in patients with decompensated heart failure: analysis from the Acute Decompensated Heart Failure National Registry (ADHERE)
    Marie Galvao
    Congestive Heart Failure Program, Division of Cardiology, Montefiore Medical Center, 7th Floor, 3400 Bainbridge Avenue, Bronx, NY 10467, USA
    J Card Fail 12:100-7. 2006
    ..The impact of gender differences has not been well described in patients hospitalized with acute decompensated heart failure (ADHF)...
  83. ncbi request reprint Managed care interventions for improving outcomes in acute heart failure syndromes
    Sadiya Sana Khan
    Division of Cardiology, Northwestern University, Feinberg School of Medicine, 201 E Huron St, Galter 10 240, Chicago, IL 60611, USA
    Am J Manag Care 14:S273-86; quiz S287-91. 2008
    ....
  84. doi request reprint Comparison of usefulness of each of five predictors of mortality and urgent transplantation in patients with advanced heart failure
    Amit Sachdeva
    Department of Medicine, University of California, Los Angeles, Medical Center, Los Angeles, California, USA
    Am J Cardiol 106:830-5. 2010
    ....
  85. ncbi request reprint Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database
    Clyde W Yancy
    Division of Cardiology, Department of Medicine, University of Texas Southwest Medical Center, Dallas, Texas 75390 9047, USA
    J Am Coll Cardiol 47:76-84. 2006
    ..Medical treatment strategies for patients with preserved systolic function are inconsistent and reflect the need for efficacious evidence-based treatment regimens...
  86. ncbi request reprint B-type natriuretic peptide levels in obese patients with advanced heart failure
    Tamara B Horwich
    Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, Los Angeles, California 90095 1679, USA
    J Am Coll Cardiol 47:85-90. 2006
    ..Despite relatively lower levels of BNP in overweight and obesity, BNP predicts worse symptoms, impaired hemodynamics, and higher mortality in HF at all levels of BMI...
  87. pmc Metformin therapy and outcomes in patients with advanced systolic heart failure and diabetes
    Digish D Shah
    Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Card Fail 16:200-6. 2010
    ..We investigated the association between metformin therapy and outcomes in a cohort of advanced, systolic HF patients with DM...
  88. ncbi request reprint Beta-blockers for the post-myocardial infarction patient: current clinical evidence and practical considerations
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Rev Cardiovasc Med 7:1-9. 2006
    ....
  89. ncbi request reprint Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE)
    Kirkwood F Adams
    Division of Cardiology, University of North Carolina, Chapel Hill, NC, USA
    Am Heart J 149:209-16. 2005
    ..Most available data on these patients are limited by patient selection criteria and study design of clinical trials and single-center studies...
  90. pmc The relationship between body mass index and cardiopulmonary exercise testing in chronic systolic heart failure
    Tamara B Horwich
    Ronald Reagan UCLA Medical Center, Los Angeles, CA 90095 1679, USA
    Am Heart J 158:S31-6. 2009
    ..The objective of this study was to assess the relationship between BMI and CPX variables, including peak oxygen uptake (VO(2)) at ventilatory threshold, oxygen pulse, and ventilation-carbon dioxide production ratio...
  91. doi request reprint Acute heart failure syndromes in patients with coronary artery disease early assessment and treatment
    James D Flaherty
    Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    J Am Coll Cardiol 53:254-63. 2009
    ..Prospective studies of the assessment and treatment of CAD in patients with AHFS are urgently needed...
  92. doi request reprint Quality of care and in-hospital outcomes in patients with coronary heart disease in rural and urban hospitals (from Get With the Guidelines-Coronary Artery Disease Program)
    Amrut V Ambardekar
    Division of Cardiology, Denver Health Medical Center, The University of Colorado at Denver and the Health Sciences Center, Denver, Colorado, USA
    Am J Cardiol 105:139-43. 2010
    ..87 to 1.26). In conclusion, within the GWTG-CAD quality improvement initiative, patients with CAD treated at rural hospitals receive similar quality of care and have similar outcomes as those at urban centers...
  93. doi request reprint Cholesterol levels and in-hospital mortality in patients with acute decompensated heart failure
    Tamara B Horwich
    Ahmanson UCLA Cardiomyopathy Center, University of California, Los Angeles, CA 90095 1679, USA
    Am Heart J 156:1170-6. 2008
    ..However, the relationship between lipid levels and outcomes in acute HF has not been studied. This study investigates the relationship between cholesterol levels and in-hospital mortality in patients hospitalized with acute HF...
  94. ncbi request reprint Beta-blocker therapy for heart failure: the standard of care
    David A Cesario
    Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, UCLA School of Medicine, Los Angeles, CA, USA
    Rev Cardiovasc Med 3:14-21. 2002
    ..Beta-blockers, along with angiotensin-converting enzyme inhibitors and aldosterone antagonists, now represent the standard of care for patients with heart failure...
  95. ncbi request reprint Quality of care and outcomes in acute decompensated heart failure: The ADHERE Registry
    Clyde W Yancy
    University of Texas Southwestern Medical Center, Division of Cardiology, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Curr Heart Fail Rep 1:121-8. 2004
    ..These patient data have been reviewed and reveal important findings regarding acute decompensated heart failure and potential opportunities to improve the quality of care...
  96. ncbi request reprint Relationship between anemia, cardiac troponin I, and B-type natriuretic peptide levels and mortality in patients with advanced heart failure
    Sonia Ralli
    Division of Cardiology, Ahmanson UCLA Cardiomyopathy Center, Los Angeles, CA 90095 1679, USA
    Am Heart J 150:1220-7. 2005
    ..This study aimed to evaluate the relationship between hemoglobin (Hb), cardiac troponin I (cTnI), B-type natriuretic peptide (BNP), and mortality in patients with advanced heart failure (HF)...
  97. ncbi request reprint Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarction
    Frederick A Spencer
    Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Arch Intern Med 164:2162-8. 2004
    ..It has been suggested that withdrawal of statin therapy during an acute coronary syndrome may attenuate any benefits of pretreatment, thereby providing indirect evidence of the importance of their non-lipid-lowering effects...
  98. ncbi request reprint Insulin-treated diabetes is associated with a marked increase in mortality in patients with advanced heart failure
    Stephanie Smooke
    Ahmanson UCLA Cardiomyopathy Center, Los Angeles, Calif 90095 1679, USA
    Am Heart J 149:168-74. 2005
    ..This study aimed to investigate the effect of diabetes and insulin use on survival in a large cohort of patients with advanced heart failure (HF) of multiple etiologies...
  99. ncbi request reprint The Acute Decompensated Heart Failure National Registry (ADHERE): opportunities to improve care of patients hospitalized with acute decompensated heart failure
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Rev Cardiovasc Med 4:S21-30. 2003
    ..If successfully implemented, the improvements in short- and long-term clinical outcomes for ADHF patients are expected to be substantial...
  100. ncbi request reprint New insights into understanding cardiometabolic risk. Introduction
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, UCLA Preventive Cardiology Program, UCLA Division of Cardiology, Los Angeles, California, USA
    Rev Cardiovasc Med 8:S1-2. 2007
  101. ncbi request reprint The role of in-hospital initiation of cardiovascular protective therapies to improve treatment rates and clinical outcomes
    Gregg C Fonarow
    Ahmanson UCLA Cardiomyopathy Center, Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Rev Cardiovasc Med 4:S37-46. 2003
    ....

Research Grants1

  1. ACTION - A CHF Trial Investigating Outcomes of Exercise
    Gregg Fonarow; Fiscal Year: 2006
    ..The trial will take place over 5 years with an initial 6 months for planning, training, and implementation; 3 years of enrollment; 1 year of follow-up; and 6 months for close out, analysis, and presentation. ..