A R Folsom

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc The association of the ankle-brachial index with incident coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study, 1987-2001
    Beth D Weatherley
    Duke Clinical Research Institute, Duke University Medical Center, P, O, Box 17969, Durham, NC 27715, USA
    BMC Cardiovasc Disord 7:3. 2007
  2. pmc The association of spatial T wave axis deviation with incident coronary events. The ARIC cohort
    Georgeta D Vaidean
    Department of Epidemiology, University of North Carolina at Chapel Hill, USA
    BMC Cardiovasc Disord 5:2. 2005
  3. ncbi request reprint Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Am J Hematol 71:285-90. 2002
  4. ncbi request reprint Association of C-reactive protein with markers of prevalent atherosclerotic disease
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
    Am J Cardiol 88:112-7. 2001
  5. ncbi request reprint Association of traditional and nontraditional cardiovascular risk factors with coronary artery calcification
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Angiology 55:613-23. 2004
  6. ncbi request reprint Magnesium intake and reduced risk of colon cancer in a prospective study of women
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Am J Epidemiol 163:232-5. 2006
  7. ncbi request reprint Association of endogenous hormones with C-reactive protein, fibrinogen, and white blood count in post-menopausal women
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
    Eur J Epidemiol 20:1015-22. 2005
  8. ncbi request reprint Fibrinolytic factors and atherothrombotic events: epidemiological evidence
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1051, USA
    Ann Med 32:85-91. 2000
  9. ncbi request reprint Prediction of coronary heart disease in middle-aged adults with diabetes
    Aaron R Folsom
    University of Minnesota, School of Public Health, Division of Epidemiology, Minneapolis, Minnesota 55454 1015, USA
    Diabetes Care 26:2777-84. 2003
  10. ncbi request reprint Hemostatic risk factors for atherothrombotic disease: an epidemiologic view
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Thromb Haemost 86:366-73. 2001

Research Grants

Collaborators

Detail Information

Publications153 found, 100 shown here

  1. pmc The association of the ankle-brachial index with incident coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study, 1987-2001
    Beth D Weatherley
    Duke Clinical Research Institute, Duke University Medical Center, P, O, Box 17969, Durham, NC 27715, USA
    BMC Cardiovasc Disord 7:3. 2007
    ....
  2. pmc The association of spatial T wave axis deviation with incident coronary events. The ARIC cohort
    Georgeta D Vaidean
    Department of Epidemiology, University of North Carolina at Chapel Hill, USA
    BMC Cardiovasc Disord 5:2. 2005
    ....
  3. ncbi request reprint Prospective study of the G20210A polymorphism in the prothrombin gene, plasma prothrombin concentration, and incidence of venous thromboembolism
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Am J Hematol 71:285-90. 2002
    ..38). There was no association between venous thromboembolism and plasma prothrombin antigen level. We estimated that the G20210A polymorphism may account for approximately 2.5% of venous thromboembolism events in United States whites...
  4. ncbi request reprint Association of C-reactive protein with markers of prevalent atherosclerotic disease
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
    Am J Cardiol 88:112-7. 2001
    ..Because CRP has been associated with clinical events, it could be that elevated CRP may be a stronger marker of thrombotic risk than of the degree of atherosclerosis...
  5. ncbi request reprint Association of traditional and nontraditional cardiovascular risk factors with coronary artery calcification
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Angiology 55:613-23. 2004
    ..These findings reaffirmed the established role of traditional risk factors in the etiology of coronary artery disease, as assessed by computed tomography, but did not identify any important nontraditional risk factors...
  6. ncbi request reprint Magnesium intake and reduced risk of colon cancer in a prospective study of women
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Am J Epidemiol 163:232-5. 2006
    ..If replicated by other observational studies, a clinical trial would be needed to determine whether it is magnesium, specifically, and not other aspects of the contributing foods, that may offer benefit...
  7. ncbi request reprint Association of endogenous hormones with C-reactive protein, fibrinogen, and white blood count in post-menopausal women
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
    Eur J Epidemiol 20:1015-22. 2005
    ..In conclusion, several endogenous sex hormones may influence basal levels of inflammatory markers. Obesity appears to play a modulating role...
  8. ncbi request reprint Fibrinolytic factors and atherothrombotic events: epidemiological evidence
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1051, USA
    Ann Med 32:85-91. 2000
    ..At present, it seems premature to recommend routine measurement of fibrinolytic factors to identify patients at risk of cardiovascular disease events. Some directions for future research on this topic are offered...
  9. ncbi request reprint Prediction of coronary heart disease in middle-aged adults with diabetes
    Aaron R Folsom
    University of Minnesota, School of Public Health, Division of Epidemiology, Minneapolis, Minnesota 55454 1015, USA
    Diabetes Care 26:2777-84. 2003
    ..To determine the 10-year probability of coronary heart disease (CHD) in diabetic adults and how well basic and novel risk factors predict CHD risk...
  10. ncbi request reprint Hemostatic risk factors for atherothrombotic disease: an epidemiologic view
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Thromb Haemost 86:366-73. 2001
    ..Thus, prospective epidemiologic studies have identified several potential hemostatic markers of atherothrombosis risk, but their causal role and clinical utility in risk prediction remain incompletely established...
  11. ncbi request reprint Fish intake, marine omega-3 fatty acids, and mortality in a cohort of postmenopausal women
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Am J Epidemiol 160:1005-10. 2004
    ..Nevertheless, the authors of this 1986-2000 study could not verify that fish and marine omega-3 fatty acid intake had independent health benefits in these postmenopausal women...
  12. ncbi request reprint C-reactive protein and incident coronary heart disease in the Atherosclerosis Risk In Communities (ARIC) study
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minn 55454 1015, USA
    Am Heart J 144:233-8. 2002
    ..C-reactive protein, a plasma marker of inflammation, is a marker of CHD risk but has been studied in few prospective investigations of the general population...
  13. ncbi request reprint Diabetes as a risk factor for death following endometrial cancer
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Gynecol Oncol 94:740-5. 2004
    ..To determine whether several personal or lifestyle risk factors for the occurrence of endometrial cancer are also risk factors for death following endometrial cancer...
  14. ncbi request reprint Estrogen replacement therapy and ovarian cancer
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota55454 1015, USA
    Epidemiology 15:100-4. 2004
    ..However, several subsequent studies have suggested that long-term ERT could increase ovarian cancer risk...
  15. ncbi request reprint Glycemic index, glycemic load, and incidence of endometrial cancer: the Iowa women's health study
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
    Nutr Cancer 46:119-24. 2003
    ..02) among nondiabetic women, but the trend was in the opposite direction among diabetic women. Our study indicates that a higher dietary glycemic load may be a risk factor for endometrial cancer incidence in nondiabetic women...
  16. ncbi request reprint A prospective study of venous thromboembolism in relation to factor V Leiden and related factors
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Blood 99:2720-5. 2002
    ....
  17. ncbi request reprint Prospective study of fibrinolytic markers and venous thromboembolism
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454 1015, USA
    J Clin Epidemiol 56:598-603. 2003
    ..There was weak evidence for an interaction of PAP with elevated factor VIIIc and elevated D-dimer in augmenting VTE risk. We conclude that, for the most part, these fibrinolytic markers do not identify healthy subjects at risk for VTE...
  18. ncbi request reprint B vitamin status and inflammatory markers
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Atherosclerosis 169:169-74. 2003
    ..In ostensibly healthy adults, B-vitamin status is not a strong correlate of circulating levels of inflammatory markers, cellular adhesion molecules, or thrombogenic factors...
  19. ncbi request reprint Protein C, antithrombin, and venous thromboembolism incidence: a prospective population-based study
    Aaron R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Arterioscler Thromb Vasc Biol 22:1018-22. 2002
    ..Attributable risk estimates suggest that low protein C levels account for approximately 2.5% of venous thromboembolic events in the ARIC population...
  20. ncbi request reprint Associations of general and abdominal obesity with multiple health outcomes in older women: the Iowa Women's Health Study
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, 1300 S Second St, Suite 300, Minneapolis, MN 55454 1015, USA
    Arch Intern Med 160:2117-28. 2000
    ....
  21. pmc Degree of concordance with DASH diet guidelines and incidence of hypertension and fatal cardiovascular disease
    Aaron R Folsom
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Hypertens 20:225-32. 2007
    ..Guidelines to prevent and treat hypertension advocate the Dietary Approaches to Stop Hypertension (DASH) diet...
  22. ncbi request reprint An assessment of incremental coronary risk prediction using C-reactive protein and other novel risk markers: the atherosclerosis risk in communities study
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Arch Intern Med 166:1368-73. 2006
    ..There has been interest in recent years in whether additional, and in particular novel, risk factors or blood markers, such as C-reactive protein, can enhance existing coronary heart disease (CHD) prediction models...
  23. pmc Physical activity and incident diabetes mellitus in postmenopausal women
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Am J Public Health 90:134-8. 2000
    ..This study determined whether the incidence of diabetes is reduced among physically active older women...
  24. ncbi request reprint Factor VII coagulant activity, factor VII -670A/C and -402G/A polymorphisms, and risk of venous thromboembolism
    A R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    J Thromb Haemost 5:1674-8. 2007
    ..Our Longitudinal Investigation of Thromboembolism Etiology (LITE) had, in contrast, reported an independent, increased risk of VTE after 7.8 years of follow-up for those with high baseline levels of FVII:C...
  25. ncbi request reprint Sequence variation in proprotein convertase subtilisin/kexin type 9 serine protease gene, low LDL cholesterol, and cancer incidence
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA
    Cancer Epidemiol Biomarkers Prev 16:2455-8. 2007
    ..05 (95% CI, 0.78-1.40) in blacks and 1.16 (95% CI, 0.99-1.36) in whites. These data suggest that a lifelong low cholesterol concentration, as reflected by these PCSK9 variants, does not increase risk of cancer...
  26. ncbi request reprint Prospective associations of fasting insulin, body fat distribution, and diabetes with risk of ischemic stroke. The Atherosclerosis Risk in Communities (ARIC) Study Investigators
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Diabetes Care 22:1077-83. 1999
    ..We tested the hypothesis that diabetes, body fat distribution, and (in nondiabetic subjects) fasting insulin levels are positively associated with ischemic stroke incidence in the general population...
  27. pmc Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 S Second St, Minneapolis, MN 55454 1015, USA
    Diabetes Care 31:905-9. 2008
    ..The purpose of this study was to determine whether a variation in the transcription factor 7-like 2 (TCF7L2) gene, which influences diabetes risk, is associated with incidence of cancers...
  28. ncbi request reprint Frailty and risk of venous thromboembolism in older adults
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 South Second St, Minneapolis, MN 55454 1015, USA
    J Gerontol A Biol Sci Med Sci 62:79-82. 2007
    ..Recent evidence links frailty to activation of coagulation and inflammatory pathways. We aimed to determine whether frailty in community-dwelling older adults is a risk factor for venous thromboembolism (VTE)...
  29. pmc Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease
    Aaron R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454, United States
    Atherosclerosis 202:211-5. 2009
    ..We hypothesized that variants in PCSK9 that lower LDL cholesterol levels are associated with reduced prevalence and incidence of peripheral artery disease (PAD)...
  30. ncbi request reprint Arterial distensibility and physical activity in the ARIC study
    K H Schmitz
    Division of Epidemiology, University of Minnesota, 1300 South 2nd St, Minneapolis, MN 55454, USA
    Med Sci Sports Exerc 33:2065-71. 2001
    ..We tested the hypothesis that self-reported sport, leisure, and work physical activity is associated with greater arterial distensibility (i.e., carotid artery pulsatile diameter changes)...
  31. ncbi request reprint A prospective study of coronary heart disease in relation to fasting insulin, glucose, and diabetes. The Atherosclerosis Risk in Communities (ARIC) Study
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Diabetes Care 20:935-42. 1997
    ..To determine the association of coronary heart disease (CHD) incidence with diabetes, fasting serum glucose, and insulin in a biracial cohort of middle-aged men and women...
  32. ncbi request reprint Associations of fat distribution and obesity with hypertension in a bi-ethnic population: the ARIC study. Atherosclerosis Risk in Communities Study
    M M Harris
    School of Public Health, University North Carolina at Chapel Hill, USA
    Obes Res 8:516-24. 2000
    ..To examine associations of hypertension with obesity and fat distribution among African American and white men and women...
  33. ncbi request reprint Plasma fibrinogen and incident hypertension in the Atherosclerosis Risk in Communities (ARIC) Study
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    J Hypertens 16:1579-83. 1998
    ..Other studies have reported a positive association between hypertension and whole-blood or plasma viscosity, to which fibrinogen contributes. To our knowledge, there has been no prospective study of fibrinogen and incident hypertension...
  34. ncbi request reprint Physical activity and incident hypertension in black and white adults: the Atherosclerosis Risk in Communities Study
    M A Pereira
    Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota 55455 1015, USA
    Prev Med 28:304-12. 1999
    ..This study examined physical activity and clinically determined incident hypertension in black and white men and women of the Atherosclerosis Risk in Communities (ARIC) Study...
  35. ncbi request reprint Risk factors for ischemic stroke subtypes: the Atherosclerosis Risk in Communities study
    Tetsuya Ohira
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S 2nd St, Minneapolis, MN 55454 1015, USA
    Stroke 37:2493-8. 2006
    ..To evaluate risk factors for ischemic stroke by its subtypes may contribute to more effective prevention of ischemic stroke, but few prospective studies have characterized risk factors for specific subtypes of ischemic stroke...
  36. ncbi request reprint Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) study
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Circulation 98:204-10. 1998
    ..Elevated plasma total homocysteine (tHcy), low B-vitamin intake, and genetic polymorphisms related to tHcy metabolism may play roles in coronary heart disease (CHD). More prospective studies are needed...
  37. ncbi request reprint Well-done meat intake and the risk of breast cancer
    W Zheng
    Division of Epidemiology, University of Minnesota School of Public Health, Minneapolis, USA
    J Natl Cancer Inst 90:1724-9. 1998
    ..We conducted a nested, case-control study among 41836 cohort members of the Iowa Women's Health Study to evaluate the potential role of heterocyclic amines and intake of well-done meat in the risk for human breast cancer...
  38. ncbi request reprint N-acetyltransferase 1 genetic polymorphism, cigarette smoking, well-done meat intake, and breast cancer risk
    W Zheng
    Division of Epidemiology, University of Minnesota School of Public Health, Minneapolis 55454, USA
    Cancer Epidemiol Biomarkers Prev 8:233-9. 1999
    ..5-62.7). The association of the NAT1*10 allele with breast cancer was mainly confined to former smokers (OR = 3.3, 95% CI = 1.2-9.5). These findings are consistent with a role for the NAT1 gene in the etiology of human breast cancer...
  39. pmc Metabolic syndrome and risk of venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology
    L M Steffen
    Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454, USA
    J Thromb Haemost 7:746-51. 2009
    ..We tested the hypothesis that the incidence of non-cancer-related venous thromboembolism (VTE) is higher among adults with MetSyn and further, that associations are stronger for idiopathic than secondary VTE...
  40. ncbi request reprint Whole grain intake and incident endometrial cancer: the Iowa Women's Health Study
    C M Kasum
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
    Nutr Cancer 39:180-6. 2001
    ..There also was no association between refined grain intake and endometrial cancer. Whole grain intake may protect against endometrial cancer among never-users of hormone replacement therapy...
  41. ncbi request reprint Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women
    K K Nicodemus
    University of Minnesota, Minneapolis, Minnesota, USA
    Diabetes Care 24:1192-7. 2001
    ..Strategies to prevent osteoporosis and/or falling may be especially warranted in women with diabetes...
  42. ncbi request reprint Trends in acute coronary heart disease mortality, morbidity, and medical care from 1985 through 1997: the Minnesota heart survey
    P G McGovern
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, USA
    Circulation 104:19-24. 2001
    ..Coronary heart disease (CHD) mortality continued to decline from 1985 to 1997...
  43. ncbi request reprint Serum leptin and weight gain over 8 years in African American and Caucasian young adults
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Obes Res 7:1-8. 1999
    ..Little information exists on whether the serum leptin concentration influences long-term weight changes in the free-living population...
  44. ncbi request reprint Association of family history of cervical, ovarian, and uterine cancer with histological categories of lung cancer: the Iowa Women's Health Study
    K E Anderson
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, USA
    Cancer Epidemiol Biomarkers Prev 6:401-5. 1997
    ....
  45. ncbi request reprint Ankle-brachial index and 7-year ischemic stroke incidence: the ARIC study
    A W Tsai
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, USA
    Stroke 32:1721-4. 2001
    ..03). CONCLUSIONS: Low ABI was strongly associated with increased incidence of ischemic stroke, but the relationship was substantially reduced after adjustment for major cardiovascular risk factors...
  46. ncbi request reprint Determinants of population changes in fibrinogen and factor VII over 6 years: the Atherosclerosis Risk in Communities (ARIC) Study
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Arterioscler Thromb Vasc Biol 20:601-6. 2000
    ..Thus, our longitudinal data suggest with some exceptions that adverse changes in cardiovascular risk factors are accompanied by increases in plasma levels of fibrinogen and factor VII...
  47. ncbi request reprint ABO blood group, other risk factors and incidence of venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE)
    T Ohira
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    J Thromb Haemost 5:1455-61. 2007
    ..Numerous case-control studies have reported higher prevalence of non-O blood type among venous thromboembolism (VTE) patients than controls, but potential mechanisms or effect modifiers for the association are not fully established...
  48. ncbi request reprint Lack of association between the angiotensin-converting enzyme insertion/deletion polymorphism and plasminogen activator inhibitor-1 antigen levels in the National Heart, Lung, and Blood Institute Family Heart Study
    J S Pankow
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, 27514, USA
    Blood Coagul Fibrinolysis 11:551-8. 2000
    ..Our findings suggest that the ACE insertion/deletion polymorphism has relatively little, if any, influence on circulating PAI-1 levels in the population at large...
  49. ncbi request reprint Risk factors for cardiovascular event recurrence in the Atherosclerosis Risk in Communities (ARIC) study
    Keattiyoat Wattanakit
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minn 55454 1015, USA
    Am Heart J 149:606-12. 2005
    ..However, few studies have examined whether established risk factors, novel blood markers, carotid ultrasonography, or ankle-brachial index can predict recurrent CVD events...
  50. pmc Genetic admixture is associated with plasma hemostatic factor levels in self-identified African Americans and Hispanics: the Multi-Ethnic Study of Atherosclerosis
    P L Lutsey
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA
    J Thromb Haemost 10:543-9. 2012
    ..Epidemiologic studies report that self-identified African Americans typically have higher hemostatic factor levels than do self-identified Caucasians or Hispanics...
  51. ncbi request reprint Gene-environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities study
    M L Grove
    The University of Texas Health Science Center at Houston, School of Public Health, Human Genetics Center, Houston, TX 77030, USA
    Int J Obes (Lond) 31:919-26. 2007
    ..The purpose of this study was to investigate the interaction between the G-protein beta-3 (GNB3) 825C>T polymorphism and physical activity in relation to prevalent obesity and hypertension...
  52. ncbi request reprint Fibrinogen, plasminogen activator inhibitor-1, and carotid intima-media wall thickness in the NHLBI Family Heart Study
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Thromb Haemost 79:400-4. 1998
    ....
  53. ncbi request reprint Helicobacter pylori seropositivity and coronary heart disease incidence. Atherosclerosis Risk In Communities (ARIC) Study Investigators
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Circulation 98:845-50. 1998
    ..However, there has been no prospective study of this association involving an ethnically diverse sample of middle-aged men and women...
  54. ncbi request reprint Risk factors for breast cancer in elderly women
    Carol Sweeney
    University of Minnesota, Minneapolis, MN, USA
    Am J Epidemiol 160:868-75. 2004
    ..67, 95% CI: 0.51, 0.88 for five or more births compared with one or two). Obesity, a modifiable risk factor, remained positively associated with breast cancer for all age groups of postmenopausal women...
  55. pmc Is whole grain intake associated with reduced total and cause-specific death rates in older women? The Iowa Women's Health Study
    D R Jacobs
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Am J Public Health 89:322-9. 1999
    ..This study sought to determine whether nutrient-rich whole grains reduce mortality risk...
  56. ncbi request reprint Migraine and other headaches: associations with Rose angina and coronary heart disease
    K M Rose
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, 137 E Franklin St, Suite 306, Chapel Hill, NC 27514, USA
    Neurology 63:2233-9. 2004
    ..To examine the association between a lifetime history of migraines and other headaches with and without aura and Rose angina and coronary heart disease (CHD)...
  57. ncbi request reprint Diabetes and endometrial cancer in the Iowa women's health study
    K E Anderson
    Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota 55454, USA
    Cancer Epidemiol Biomarkers Prev 10:611-6. 2001
    ..64 (95% CI, 1.16-2.31). We conclude that after adjustment for other risk factors, diabetes is associated with a modestly increased risk for endometrial cancer among women in this cohort...
  58. pmc Peak thrombin generation and subsequent venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE) study
    P L Lutsey
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454, USA
    J Thromb Haemost 7:1639-48. 2009
    ..Thrombin is an enzyme that is essential for the acceleration of the coagulation cascade and the conversion of fibrinogen to clottable fibrin...
  59. pmc TCF7L2 single nucleotide polymorphisms, cardiovascular disease and all-cause mortality: the Atherosclerosis Risk in Communities (ARIC) study
    S J Bielinski
    Division of Epidemiology and Community Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454, USA
    Diabetologia 51:968-70. 2008
    ..We hypothesised that TCF7L2 single nucleotide polymorphisms (SNPs) are associated with cardiovascular disease (CVD) and that the associations differ in diabetic and non-diabetic persons...
  60. ncbi request reprint Coronary heart disease trends in four United States communities. The Atherosclerosis Risk in Communities (ARIC) study 1987-1996
    W D Rosamond
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27514, USA
    Int J Epidemiol 30:S17-22. 2001
    ....
  61. ncbi request reprint APOE genotype and cognitive decline in a middle-aged cohort
    C K Blair
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Neurology 64:268-76. 2005
    ..However, most studies involved elderly samples (aged 65+) and were not large enough to examine the three APOE alleles separately...
  62. ncbi request reprint Association between nonsteroidal anti-inflammatory drug use and the incidence of lung cancer in the Iowa women's health study
    Jennifer H Hayes
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 South Second Street, Minneapolis, MN 55454 1015, USA
    Cancer Epidemiol Biomarkers Prev 15:2226-31. 2006
    ....
  63. ncbi request reprint Coagulation factors, inflammation markers, and venous thromboembolism: the longitudinal investigation of thromboembolism etiology (LITE)
    Albert W Tsai
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Med 113:636-42. 2002
    ..We sought to assess prospectively whether higher levels of blood coagulation factors and inflammation markers are risk factors for venous thromboembolism...
  64. ncbi request reprint Association of aspirin and nonsteroidal anti-inflammatory drug use with breast cancer
    Trista W Johnson
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
    Cancer Epidemiol Biomarkers Prev 11:1586-91. 2002
    ....
  65. ncbi request reprint Weight variability and mortality: the Iowa Women's Health Study
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454 1015, USA
    Int J Obes Relat Metab Disord 20:704-9. 1996
    ..To evaluate the association between weight variability and risk of mortality in women...
  66. pmc Serological evidence of infections and Type 2 diabetes: the MultiEthnic Study of Atherosclerosis
    P L Lutsey
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    Diabet Med 26:149-52. 2009
    ..The aim of this study was to examine the cross-sectional relation of seropositivity to five pathogens (Chlamydia pneumoniae, cytomegalovirus, Helicobacter pylori, hepatitis A virus, herpes simplex virus) and prevalent diabetes...
  67. ncbi request reprint Plasma hemostatic factors and endothelial markers in four racial/ethnic groups: the MESA study
    P L Lutsey
    Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, USA
    J Thromb Haemost 4:2629-35. 2006
    ..Hemostatic factors and endothelial markers may play some role in racial/ethnic differences in cardiovascular disease (CVD) rates. However, little information exists on hemostatic factors and endothelial markers across racial/ethnic groups...
  68. ncbi request reprint Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study
    J S Pankow
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, 137 East Franklin St, Suite 306, Chapel Hill, NC 27514, USA
    Atherosclerosis 154:681-9. 2001
    ..Our findings suggest that CRP levels, albumin levels, and WBC are determined at least partially by genetic factors. Further efforts to identify gene loci affecting these traits are warranted...
  69. ncbi request reprint Cardiovascular risk factors and cognitive decline in middle-aged adults
    D Knopman
    Department of Neurology, Mayo Clinic, Rochester, MN, USA
    Neurology 56:42-8. 2001
    ..Interventions aimed at hypertension or diabetes that begin before age 60 might lessen the burden of cognitive impairment in later life...
  70. ncbi request reprint The metabolic syndrome and risk of incident colorectal cancer
    Rehana L Ahmed
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
    Cancer 107:28-36. 2006
    ....
  71. ncbi request reprint Heart rate-corrected QT interval prolongation predicts risk of coronary heart disease in black and white middle-aged men and women: the ARIC study
    Jacqueline M Dekker
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
    J Am Coll Cardiol 43:565-71. 2004
    ....
  72. ncbi request reprint Incidence of colorectal cancer in relation to glycemic index and load in a cohort of women
    Mary McCarl
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 South Second Street, Minneapolis, MN 55454 1015, USA
    Cancer Epidemiol Biomarkers Prev 15:892-6. 2006
    ..Elevated circulating insulin concentrations can increase insulin-like growth factor-1, and both of these hormones may have growth-promoting effects within the colorectum...
  73. ncbi request reprint Whole-grain intake may reduce the risk of ischemic heart disease death in postmenopausal women: the Iowa Women's Health Study
    D R Jacobs
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Am J Clin Nutr 68:248-57. 1998
    ..A recent review of epidemiologic literature found consistently reduced cancer and heart disease rates in persons with high compared with low whole-grain intakes...
  74. ncbi request reprint Angiotensinogen and angiotensin converting enzyme genotypes and carotid atherosclerosis: the atherosclerosis risk in communities and the NHLBI family heart studies
    D K Arnett
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Atherosclerosis 138:111-6. 1998
    ....
  75. ncbi request reprint Absolute and attributable risks of cardiovascular disease incidence in relation to optimal and borderline risk factors: comparison of African American with white subjects--Atherosclerosis Risk in Communities Study
    Atsushi Hozawa
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Arch Intern Med 167:573-9. 2007
    ..Among white Americans, a large proportion of cardiovascular disease (CVD) events is explained by borderline or any elevated CVD risk factor levels. The degree to which this is true among African American subjects is unclear...
  76. ncbi request reprint Dietary risk factors for upper aerodigestive tract cancers
    Christine M Kasum
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
    Int J Cancer 99:267-72. 2002
    ..These findings confirm previous observations that high intake of fruits and vegetables and that intake of whole grains and the fiber derived from them may reduce risk of upper aerodigestive tract cancers...
  77. pmc Hemostatic and inflammatory risk factors for intracerebral hemorrhage in a pooled cohort
    Jared D Sturgeon
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S Second St, Minneapolis, MN 55454 1015, USA
    Stroke 39:2268-73. 2008
    ..The purpose of this study was to identify novel risk factors for intracerebral hemorrhagic stroke (ICH)...
  78. ncbi request reprint Risk factors for peripheral arterial disease incidence in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study
    Keattiyoat Wattanakit
    Division of Epidemiology, School of Public Health, University of Minnesota, Suite 300, 1300 South 2nd Street, Minneapolis, MN 55454 1015, USA
    Atherosclerosis 180:389-97. 2005
    ..Some risk factors for peripheral arterial disease (PAD) have been identified, but little information is available on PAD risk factors in individuals with diabetes...
  79. pmc Antioxidant intake from fruits, vegetables and other sources and risk of non-Hodgkin's lymphoma: the Iowa Women's Health Study
    Carrie A Thompson
    Department of Medicine, College of Medicine Mayo Clinic, Rochester, MN, USA
    Int J Cancer 126:992-1003. 2010
    ..In conclusion, these results support a role for vegetables, and perhaps fruits and associated antioxidants from food sources, as protective factors against the development of NHL and follicular lymphoma in particular...
  80. ncbi request reprint Beta-fibrinogen gene -455G/A polymorphism and coronary heart disease incidence: the Atherosclerosis Risk in Communities (ARIC) Study
    A R Folsom
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Ann Epidemiol 11:166-70. 2001
    ..The -455G/A (HaeIII) polymorphism of the beta-fibrinogen gene influences levels of plasma fibrinogen. We determined whether it influences risk of coronary heart disease...
  81. ncbi request reprint Serum homocysteine, thermolabile variant of methylene tetrahydrofolate reductase (MTHFR), and venous thromboembolism: Longitudinal Investigation of Thromboembolism Etiology (LITE)
    Albert W Tsai
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Am J Hematol 72:192-200. 2003
    ..74, 95% CI = 0.56-0.98). Our prospective data showed, at most, a weak relationship between homocysteine and VTE risk, with associations larger among younger participants. MTHFR C677T was not a risk factor for VTE...
  82. pmc Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study
    Alvaro Alonso
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S 2nd Street, Minneapolis, MN 55454 USA
    Am Heart J 158:111-7. 2009
    ..To define the incidence and cumulative risk of atrial fibrillation (AF) in a population-based cohort of whites and African Americans...
  83. pmc The association of hip circumference with incident hip fracture in a cohort of postmenopausal women: the Iowa Women's Health Study
    Emily D Parker
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA
    Ann Epidemiol 18:836-41. 2008
    ..As the mean age of the U.S. population increases, the public health burden of osteoporotic fractures is expected to increase. This study prospectively examined the independent association of hip circumference with hip fracture...
  84. ncbi request reprint Serum uric acid and risk of ischemic stroke: the ARIC Study
    Atsushi Hozawa
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Atherosclerosis 187:401-7. 2006
    ..We therefore investigated the relation between UA and ischemic stroke in the Atherosclerosis Risk in Communities (ARIC) Study...
  85. ncbi request reprint Electrocardiographic findings and incident coronary heart disease among participants in the Atherosclerosis Risk in Communities (ARIC) study
    Daniella B Machado
    Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, Minnesota, USA
    Am J Cardiol 97:1176-1181. 2006
    ..In conclusion, several 12-lead ECG findings were independently associated with incident CHD in middle-aged adults. With only a few exceptions, the associations were similar for blacks and whites...
  86. ncbi request reprint Diabetes mellitus and subsite-specific colorectal cancer risks in the Iowa Women's Health Study
    Paul J Limburg
    Division of Epidemiology, University of Minnesota, 1300 South Second Street, Suite 300, Minneapolis, MN 55454, USA
    Cancer Epidemiol Biomarkers Prev 14:133-7. 2005
    ....
  87. ncbi request reprint Nonsteroidal anti-inflammatory drugs and subsite-specific colorectal cancer incidence in the Iowa women's health study
    Amit Mahipal
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South Second Street, Minneapolis, MN 55454, USA
    Cancer Epidemiol Biomarkers Prev 15:1785-90. 2006
    ....
  88. ncbi request reprint Ankle-brachial index and hemostatic markers in the Atherosclerosis Risk in Communities (ARIC) study cohort
    Laura M Reich
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Vasc Med 12:267-73. 2007
    ..56-4.65), for beta-TG was 1.80 (95% CI 1.12-2.88), and for CRP was 1.57 (95% CI 0.84-2.95). Plasma levels of hemostatic and inflammatory markers are elevated in PAD, suggesting these processes are involved in the pathophysiology of PAD...
  89. ncbi request reprint Periodontitis and coronary artery calcification: the Atherosclerosis Risk in Communities (ARIC) study
    Sarah A Nakib
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454, USA
    J Periodontol 75:505-10. 2004
    ..Coronary artery calcification (CAC) is an emerging marker for atherosclerosis, and past studies suggest that it predicts incident CHD in asymptomatic populations...
  90. ncbi request reprint A hypothesis: interaction between supplemental iron intake and fermentation affecting the risk of colon cancer. The Iowa Women's Health Study
    Duk Hee Lee
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Nutr Cancer 48:1-5. 2004
    ..01). This hypothesis needs confirmation in other cohort studies because, despite the significant trend, only nine cases were included in the top category of > or = 50 mg supplemental iron, and this finding could have arisen by chance...
  91. ncbi request reprint Occurrence of unrecognized myocardial infarction in subjects aged 45 to 65 years (the ARIC study)
    Lori L Boland
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55454 1015, USA
    Am J Cardiol 90:927-31. 2002
    ..The percentage of unrecognized MIs in men and women was similar. The percentage of unrecognized MIs in the ARIC sample between 1987 and 1998 was slightly lower than previous estimates from other populations...
  92. ncbi request reprint Trends in hospitalization rate, hospital case fatality, and mortality rate of stroke by subtype in Minneapolis-St. Paul, 1980-2002
    Jared D Sturgeon
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Neuroepidemiology 28:39-45. 2007
    ..Little information exists on trends in stroke subtypes. We examined trends in mortality, hospitalization rate, and hospital case fatality of stroke by subtype in the Minneapolis-St. Paul area from 1980 to 2002...
  93. ncbi request reprint Anthropometric characteristics and risk of multiple myeloma
    Cindy K Blair
    Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA
    Epidemiology 16:691-4. 2005
    ..Few studies have examined obesity and risk for multiple myeloma, and the results are inconsistent. Laboratory evidence suggests mechanisms through which obesity could influence carcinogenesis of this hematopoietic malignancy...
  94. pmc Dietary phosphorus, blood pressure, and incidence of hypertension in the atherosclerosis risk in communities study and the multi-ethnic study of atherosclerosis
    Alvaro Alonso
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S 2nd St, Suite 300, Minneapolis, MN 55454, USA
    Hypertension 55:776-84. 2010
    ..04 (0.93 to 1.17; P for trend=0.48) for phosphorus from other foods. These findings could indicate an effect of phosphorus in conjunction with other dairy constituents or of dairy itself without involvement of phosphorus...
  95. pmc Associations between HDL-cholesterol and polymorphisms in hepatic lipase and lipoprotein lipase genes are modified by dietary fat intake in African American and White adults
    Jennifer A Nettleton
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis 55454, USA
    Atherosclerosis 194:e131-40. 2007
    ..In conclusion, these data show that plasma HDL-C differs according to LIPC, LPL, and CETP genotypes. In the case of LIPC and LPL, data suggest dietary fat modifies these relations...
  96. ncbi request reprint Lack of association of physical activity and obesity with incident pancreatic cancer in elderly women
    Penny J Sinner
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Suite 300, 1300 South Second Street, Minneapolis, Minnesota 55454 1015, USA
    Cancer Epidemiol Biomarkers Prev 14:1571-3. 2005
  97. ncbi request reprint Iron, zinc, and alcohol consumption and mortality from cardiovascular diseases: the Iowa Women's Health Study
    Duk Hee Lee
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    Am J Clin Nutr 81:787-91. 2005
    ..The relation between iron status and atherosclerosis has long been a topic of debate...
  98. ncbi request reprint The association of physical activity with lung cancer incidence in a cohort of older women: the Iowa Women's Health Study
    Penny Sinner
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 South 2nd Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Cancer Epidemiol Biomarkers Prev 15:2359-63. 2006
    ..We examined the potential association between physical activity and lung cancer in women...
  99. pmc A genetic variant on chromosome 9p21 and incident heart failure in the ARIC study
    Kazumasa Yamagishi
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, 1300 S Second Street, Suite 300, Minneapolis, MN 55454 1015, USA
    Eur Heart J 30:1222-8. 2009
    ..We tested the association of chromosome 9p21 polymorphisms with non-coronary atherosclerotic diseases...
  100. pmc Associations of obesity measures with subtypes of ischemic stroke in the ARIC Study
    Hiroshi Yatsuya
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA
    J Epidemiol 20:347-54. 2010
    ..Associations between obesity and lacunar, nonlacunar thrombotic, and cardioembolic stroke are not firmly established...
  101. ncbi request reprint Hyperinsulinemia, dyslipidemia, and obesity as risk factors for hospitalized gallbladder disease. A prospective study
    Lori L Boland
    Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    Ann Epidemiol 12:131-40. 2002
    ..Determinants of hospitalized gallbladder disease were examined in a large, population-based cohort of men and women...

Research Grants2

  1. Cardiovascular Disease Epidemiology & Prevention Trng
    Aaron Folsom; Fiscal Year: 2007
    ..The continued need for qualified cardiovascular epidemiologists and the program's documented success justify its continuance. ..