Research Topics
| DAVID R contact FLUMSummaryAffiliation: University of Washington Country: USA Publications
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Publications
Bile duct injury during cholecystectomy and survival in medicare beneficiariesDavid R Flum
Department of Surgery, University of Washington, Seattle, Washington 98195 6410, USA
JAMA 290:2168-73. 2003..Common bile duct (CBD) injury during cholecystectomy is a significant source of patient morbidity, but its impact on survival is unclear...
Has misdiagnosis of appendicitis decreased over time? A population-based analysisD R Flum
Department of Surgery, Robert Wood Johnson Clinical Scholars Program, Box 357183, H 220 Health Sciences Center, University of Washington, Seattle, WA 98195 7183, USA
JAMA 286:1748-53. 2001..Computed tomography, ultrasonography, and laparoscopy have been suggested for use in patients with equivocal signs of appendicitis to decrease unnecessary surgery...
Early mortality among Medicare beneficiaries undergoing bariatric surgical proceduresDavid R Flum
Department of Surgery, University of Washington, Seattle, Wash 98195 7183, USA
JAMA 294:1903-8. 2005..Case series demonstrate that bariatric surgery can be performed with a low rate of perioperative mortality (0.5%), but the rate among high-risk patients and the community at large is unknown...
Evaluating diagnostic accuracy in appendicitis using administrative dataDavid R Flum
Department of Surgery, University of Washington, School of Medicine, Seattle, WA 98195 7183, USA
J Surg Res 123:257-61. 2005..This study assessed the validity of a research technique using administrative data to determine whether patients undergoing an appendectomy actually had appendicitis or if they had a negative appendectomy (NA)...
Washington State's approach to variability in surgical processes/Outcomes: Surgical Clinical Outcomes Assessment Program (SCOAP)David R Flum
Department of Surgery and the Surgical Outcomes Research Center, and the Department of Health Services, University of Washington, Seattle, Washington 98195-6410, USA
Surgery 138:821-8. 2005
Toward the rational and equitable use of bariatric surgeryDavid R Flum
Department of Surgery, University of Washington, Seattle, WA 98195, USA
JAMA 298:1442-4. 2007
Development of a porcine Roux-en-Y gastric bypass survival model for the study of post-surgical physiologyDavid R Flum
Department of Surgery, University of Washington, Seattle, WA 98195 7183, USA
Obes Surg 17:1332-9. 2007..The aim of this study was to establish a survival model of Roux-en-Y gastric bypass (RYGBP) in swine and to evaluate its potential in studies of physiology...
The clinical and economic correlates of misdiagnosed appendicitis: nationwide analysisDavid R Flum
Department of Surgery, Robert Wood Johnson Clinical Scholars Program, University of Washington, H 220 Health Sciences Center, Box 357183, Seattle, WA 98195 7183, USA
Arch Surg 137:799-804; discussion 804. 2002..Negative appendectomy (NA)--the nonincidental removal of a normal appendix--occurs commonly but the associated clinical- and system-level costs are not well studied...
Common bile duct injury during laparoscopic cholecystectomy and the use of intraoperative cholangiography: adverse outcome or preventable error?D R Flum
Department of Surgery, University of Washington, Seattle, WA 98195 7183, USA
Arch Surg 136:1287-92. 2001..Common bile duct (CBD) injury is a serious complication of laparoscopic cholecystectomy (LC). Predictors of this adverse outcome have not been well documented...
Intraoperative cholangiography and risk of common bile duct injury during cholecystectomyDavid R Flum
The Robert Wood Johnson Clinical Scholars Program, The Department of Surgery, University of Washington, Seattle 98195 6410, USA
JAMA 289:1639-44. 2003..Intraoperative cholangiography (IOC) may decrease the risk of common bile duct (CBD) injury during cholecystectomy by helping to avoid misidentification of the CBD...
Have outcomes of incisional hernia repair improved with time? A population-based analysisDavid R Flum
Robert Wood Johnson Clinical Scholars Program, Seattle, Washington, USA
Ann Surg 237:129-35. 2003..To determine if certain outcomes of incisional hernia repair have improved in recent eras...
The use, safety and cost of bariatric surgery before and after Medicare's national coverage decisionDavid R Flum
University of Washington Schools of Medicine, Pharmacy and Public Health, Seattle, WA, USA
Ann Surg 254:860-5. 2011..To determine the impact of the Centers for Medicare and Medicaid Services' (CMS) bariatric surgery national coverage decision (NCD) on the use, safety, and cost of care CMS beneficiaries...
Temporal trends in the management of potentially resectable lung cancerFarhood Farjah
Surgical Outcomes Research Center, University of Washington, Seattle, Washington, USA
Ann Thorac Surg 85:1850-5; discussion 1856. 2008..We hypothesized that the proportion of patients operated on would increase over time coincident with increasing adherence to practice guidelines and improved patient/provider education over time...
Management of pleural space infections: a population-based analysisFarhood Farjah
Division of General Surgery, Department of Surgery, University of Washington, Seattle, Wash 98195 6310, USA
J Thorac Cardiovasc Surg 133:346-51. 2007..Management options for pleural space infections have changed over the last 2 decades. This study evaluated trends over time in the incidence of disease and use of different management strategies and their associated outcomes...
Surgeon knowledge, behavior, and opinions regarding intraoperative cholangiographyNader N Massarweh
Department of Surgery, University of Washington, Seattle, WA 98195 6410, USA
J Am Coll Surg 207:821-30. 2008..Routine IOC is not universal, and barriers to its use, including surgeon knowledge, behavior, and attitudes, should be understood in developing quality-improvement interventions aimed at increasing IOC use...
Multi-modality mediastinal staging for lung cancer among medicare beneficiariesFarhood Farjah
Surgical Outcomes Research Center, Department of Surgery, University of Washington, Seattle, WA 98195 6410, USA
J Thorac Oncol 4:355-63. 2009..It is unknown how frequently multimodality mediastinal staging is used, or whether its use is associated with better health outcomes...
Choosing your words carefully: how physicians would disclose harmful medical errors to patientsThomas H Gallagher
Departments of Medicine and Medical History and Ethics, University of Washington School of Medicine, 4311 11th Avenue NW, Seattle, WA 98105, USA
Arch Intern Med 166:1585-93. 2006..Little is known about how physicians approach disclosure. The objective of the present study was to describe how physicians disclose errors to patients...
Adverse events after radiofrequency ablation of unresectable liver tumors: a single-center experienceOliver B Lao
Department of Surgery, University of Washington, Seattle, WA 98195, USA
Am J Surg 198:76-82. 2009..Radiofrequency ablation (RFA) is a relatively new modality to treat liver tumors that is being incorporated into practice despite the fact that its risk profile has not been well described...
Negative appendectomy and imaging accuracy in the Washington State Surgical Care and Outcomes Assessment ProgramJoseph Cuschieri
Department of Surgery, University of Washington, Seattle, WA, USA
Ann Surg 248:557-63. 2008..The Surgical Care and Outcomes Assessment Program (SCOAP) gathers chart-abstracted process of care data (such as CT/US accuracy) for general surgical procedures (including appendectomy) at most Washington State hospitals...
Risk of emergency colectomy and colostomy in patients with diverticular diseaseDaniel A Anaya
Department of Surgery, University of Washington, Seattle 98195, USA
Arch Surg 140:681-5. 2005..Individualization of recommendations regarding elective colectomy based on these factors may be more appropriate than the application of previously published strategies...
Perioperative rofecoxib plus local anesthetic field block diminishes pain and recovery time after outpatient inguinal hernia repairDorothy J Pavlin
Department of Anesthesiology, University of Washington School of Medicine, Seattle, WA, USA
Anesth Analg 101:83-9, table of contents. 2005..We conclude that perioperative rofecoxib with PL reduces in-hospital recovery time, decreases pain scores and opioid use, and improves satisfaction scores in the first 24 h after surgery...
Primary operative versus nonoperative therapy for pediatric empyema: a meta-analysisJeffrey R Avansino
Department of Surgery, University of Washington, Box 356410, Seattle, WA 98105, USA
Pediatrics 115:1652-9. 2005..The optimal treatment of children with empyema remains controversial. The purpose of this review was to compare reported results of nonoperative and primary operative therapy for the treatment of pediatric empyema...
Wide local excision or abdominoperineal resection as the initial treatment for anorectal melanoma?John T Droesch
Department of Surgery, University of Washington, 1959 N E Pacific St, Box 356410, Seattle, WA 98195 6410, USA
Am J Surg 189:446-9. 2005..Anorectal melanoma (AM) is a rare tumor with a poor prognosis. Treatment with abdominoperineal resection (APR) over wide local excision (WLE) is still debated. This study aimed to compare median survival of WLE and APR in patients with AM...
Risk tolerance and bile duct injury: surgeon characteristics, risk-taking preference, and common bile duct injuriesNader N Massarweh
Department of Surgery, University of Washington, Seattle, WA 98195 6410, USA
J Am Coll Surg 209:17-24. 2009..Risk-taking preferences can influence physician behavior and practice. We evaluated self-reported differences in characteristics and risk-taking preference among surgeons with and without a reported history of CBDI...
A critical evaluation of the impact of Leapfrog's evidence-based hospital referralNader N Massarweh
Department of Surgery Surgical Outcomes Research Center, University ofWashington, Seattle, WA, USA
J Am Coll Surg 212:150-159.e1. 2011..It has yet to be determined if EBHR has led to regionalized surgical care and whether it has improved patient outcomes...
Lower extremity angioplasty for claudication: a population-level analysis of 30-day outcomesTodd R Vogel
Department of Surgery, Surgical Outcomes Research Center, Division of Vascular Surgery, Harborview Medical Center, Seattle, WA 98104, USA
J Vasc Surg 45:762-7. 2007..This study evaluated changes in the use and short-term outcomes of PTA among patients with claudication and other manifestations of peripheral arterial disease (PAD)...
Impact of advancing age on abdominal surgical outcomesNader N Massarweh
Department of Surgery, Surgical Outcomes Research Center, University of Washington School of Medicine, Seattle, WA 98195 6410, USA
Arch Surg 144:1108-14. 2009..To describe the population-level risk of adverse outcomes among older adults undergoing common abdominal surgical procedures...
Impact of gastric bypass operation on survival: a population-based analysisDavid R Flum
Department of Surgery, University of Washington, Seattle, WA 98195-7183, USA
J Am Coll Surg 199:543-51. 2004..A modest overall survival benefit was associated with the procedure but a marked survival advantage was noted for patients who survive to the first postoperative year...
Role of intraoperative cholangiography in avoiding bile duct injuryNader N Massarweh
Department of Surgery, University of Washington, Seattle, WA 98195-6410, USA
J Am Coll Surg 204:656-64. 2007
Trends in the operative management and outcomes of T4 lung cancerFarhood Farjah
Department of Surgery, Surgical Outcomes Research Center, University of Washington, Seattle, Washington 98195 6310, USA
Ann Thorac Surg 86:368-74. 2008..This study describes temporal trends and variables in the operative management and outcomes of patients with T4 lung tumors in the general community...
Filling the gaps in bariatric surgical researchAnita P Courcoulas
Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
JAMA 294:1957-60. 2005
A cost-effectiveness analysis of intraoperative cholangiography in the prevention of bile duct injury during laparoscopic cholecystectomyDavid R Flum
Robert Wood Johnson Clinical Scholars Program, Department of Surgery, University of Washington, Seattle, WA 98195-7183, USA
J Am Coll Surg 196:385-93. 2003..Routine IOC use among less experienced surgeons and in high-risk operations is the most cost effective, but the cost implications of routine use for the general population should also be considered cost effective...
Cost-effectiveness analysis of laparoscopic gastric bypass, adjustable gastric banding, and nonoperative weight loss interventionsLeon Salem
Department of Surgery, University of Washington School of Medicine, Seattle, Washington 98195 6410, USA
Surg Obes Relat Dis 4:26-32. 2008..We designed a model to evaluate the incremental cost-effectiveness of these procedures compared with nonoperative weight loss interventions and with each other...
Surgeon specialty and long-term survival after pulmonary resection for lung cancerFarhood Farjah
Department of Surgery, University of Washington, Seattle, Washington 98195, USA
Ann Thorac Surg 87:995-1004; discussion 1005-6. 2009..Long-term outcomes and processes of care in patients undergoing pulmonary resection for lung cancer may vary by surgeon type. Associations between surgeon specialty and processes of care and long-term survival have not been described...
Impact of surgical clipping on survival in unruptured and ruptured cerebral aneurysms: a population-based studyGavin W Britz
Department of Neurosurgery, University of Washington, Seattle, Wash 98195-6410, USA
Stroke 35:1399-403. 2004..Patients with unruptured aneurysms who undergo clipping have improved survival compared with those who do not undergo clipping. This study supports the use of early intervention in the management of patients with unruptured aneurysms...
The impact of low health literacy on surgical practiceLisa D Chew
VA Puget Sound Health Care System, Health Services Research and Development S 152, 1660 S Columbian Way, Seattle, WA 98108, USA
Am J Surg 188:250-3. 2004..We sought to determine the prevalence of low health literacy (LHL) among patients in a preoperative clinic, the characteristics associated with LHL, and the association between LHL and adherence to preoperative instructions...
The nationwide frequency of major adverse outcomes in antireflux surgery and the role of surgeon experience, 1992-1997David R Flum
Department of Surgery, University of Washington, Seattle 98195-7183, USA
J Am Coll Surg 195:611-8. 2002..Surgical experience with the procedure was linked to better outcomes...
Health care utilization among surgically treated Medicare beneficiaries with lung cancerFarhood Farjah
Department of Surgery, University of Washington, Seattle, Washington 98195 6410, USA
Ann Thorac Surg 88:1749-56. 2009..Markers of increased health care utilization are surrogates for adverse events, and one such metric--prolonged length of stay greater than 14 days (PLOS)--was recently endorsed as a provider-level performance measure...
Hartmann's colectomy and reversal in diverticulitis: a population-level assessmentLeon Salem
Department of Surgery, University of Washington, Seattle, Washington 98195-6410, USA
Dis Colon Rectum 48:988-95. 2005..We identified a higher than expected mortality rate among older patients undergoing colostomy reversal. The impact of colostomy and reversal operations on both patients and the health care system is significant...
Risk taking and tolerance of uncertainty: implications for surgeonsEric P Tubbs
Department of Surgery, University of Washington, Seattle, Washington 98195-6410, USA
J Surg Res 131:1-6. 2006..Understanding the behaviors, attitudes and beliefs that make up surgical "judgment" remains a challenge for those interested in influencing behavior...
Misdiagnosis of appendicitis and the use of diagnostic imagingDavid R Flum
Department of Surgery, University of Washington, Seattle, WA 98195-6410, USA
J Am Coll Surg 201:933-9. 2005..This study cautions against overreliance on CT/US in diagnosing appendicitis and emphasizes the need for test benchmarking in routine practice before establishing protocols for presumed appendicitis...
Safety and efficacy of video-assisted versus conventional lung resection for lung cancerFarhood Farjah
Department of Surgery, Surgical Outcomes Research Center, University of Washington, Seattle, Wash 98195 6310, USA
J Thorac Cardiovasc Surg 137:1415-21. 2009..We sought to evaluate the use of video-assisted thoracoscopy among patients with lung cancer and its safety and effectiveness relative to conventional resection...
Epithelioid sarcoma: the University of Washington experiencePatrick S Wolf
University of Washington Medical Center, Seattle, WA 98195, USA
Am J Surg 196:407-12. 2008..Epithelioid sarcoma is a rare sarcoma with a high local recurrence rate that frequently metastasizes to lymph nodes. We reviewed our experience with adjuvant therapy in patients with this disease...
Temporal changes in the management of diverticulitisLeon Salem
Department of Surgery, University of Washington, Seattle, WA 98195-6410, USA
J Surg Res 124:318-23. 2005..The proportion of patients undergoing colostomy remained stable, and there does not seem to be a significant increase in the use of one-stage procedures for diverticulitis...
Prophylactic cholecystectomy in transplant patients: a decision analysisLillian S Kao
Department of Surgery, LBJ General Hospital, University of Texas Health Science Center at Houston, Houston, Texas 77026, USA
J Gastrointest Surg 9:965-72. 2005..Expectant management is the preferred strategy for pancreas and/or kidney transplant recipients with asymptomatic cholelithiasis...
Reproductive health of women electing bariatric surgeryGabriella G Gosman
University of Pittsburgh, School of Medicine, Magee Womens Hospital, Pittsburgh, Pennsylvania 15213, USA
Fertil Steril 94:1426-31. 2010..To describe the reproductive health history and characteristics of women having bariatric surgery and to determine whether this differs by age of onset of obesity...
Trends in the utilization and impact of radiofrequency ablation for hepatocellular carcinomaNader N Massarweh
Department of Surgery, University of Washington, Seattle, WA 98195 6410, USA
J Am Coll Surg 210:441-8. 2010..The incidence of hepatocellular carcinoma (HCC) is rising and radiofrequency ablation (RFA) appears to be increasingly used. The nationwide use and impact of RFA have not been well characterized...
Racial disparities among patients with lung cancer who were recommended operative therapyFarhood Farjah
Surgical Outcomes Research Center, University of Washington, Seattle, Washington 98195 6410, USA
Arch Surg 144:14-8. 2009..We hypothesized that there would be no significant evidence of racial disparities among patients with early-stage lung cancer who are recommended surgical therapy...
The significance of discharge to skilled care after abdominopelvic surgery in older adultsVictor J Legner
Department of Medicine, University of Washington School of Medicine, Seattle, 98195 6410, USA
Ann Surg 249:250-5. 2009..Older adults frequently undergo abdominopelvic surgical operations, yet the risk and significance of postoperative discharge disposition has not been well characterized...
The timing of elective colectomy in diverticulitis: a decision analysisLeon Salem
Department of Surgery, University of Washington, Seattle, WA 98195-6410, USA
J Am Coll Surg 199:904-12. 2004..CONCLUSIONS: This study suggests that expectant management is associated with lower rates of death and colostomy and is cost-saving for both younger and older patients...
Blueprint for a new American College of Surgeons: National Surgical Quality Improvement ProgramJohn D Birkmeyer
Department of Surgery, University of Michigan, Ann Arbor, MI, USA
J Am Coll Surg 207:777-82. 2008
Pulmonary function in the morbidly obeseJoshua A Saliman
Department of Medicine, University of Washington Medical Center, Seattle, Washington 98195, USA
Surg Obes Relat Dis 4:632-9; discussion 639. 2008..To assess the relationship between lung function tests and clinical characteristics in a cohort of morbidly obese patients undergoing evaluation for bariatric procedures in a university hospital in the United States...
Primary anastomosis or Hartmann's procedure for patients with diverticular peritonitis? A systematic reviewLeon Salem
Department of Surgery, University of Washington, Seattle, Washington 98195 6410, USA
Dis Colon Rectum 47:1953-64. 2004..This systematic literature review was designed to summarize and compare the reported outcomes of one-stage and two-stage operations for the treatment of perforated diverticulitis with peritonitis...
The costs of nonsurgical and surgical weight loss interventions: is an ounce of prevention really worth a pound of cure?Christine Jensen
Department of Surgery, University of Washington, Seattle, Washington 98195, USA
Surg Obes Relat Dis 1:353-7. 2005
A systematic review of whether oral contrast is necessary for the computed tomography diagnosis of appendicitis in adultsBrock A Anderson
Department of Surgery, University of Washington, BB 431, Seattle, WA 98195, USA
Am J Surg 190:474-8. 2005..A prospective comparative trial of CT with and without oral contrast for appendicitis should be performed to assess the adequacy of this modality...
Do antireflux operations decrease the rate of reflux-related hospitalizations in children?Adam B Goldin
Division of Pediatric General and Thoracic Surgery, Children s Hospital and Regional Medical Center, W 7729, PO Box 5371, Seattle, WA 98105 0371, USA
Pediatrics 118:2326-33. 2006..The objective of this study was to determine whether pediatric antireflux procedures are associated with a decreased rate of reflux-related hospitalizations...
Are bariatric surgical outcomes worth their cost? A systematic reviewLeon Salem
Department of Surgery, University of Washington, Seattle, WA 98195 6410, USA
J Am Coll Surg 200:270-8. 2005
The incidence and factors associated with graft infection after aortic aneurysm repairTodd R Vogel
Robert Wood Johnson Medical School, Division of Vascular Surgery, New Brunswick, NJ 08903 0019, USA
J Vasc Surg 47:264-9. 2008..We hypothesized that AGI occurs more often in patients with periprocedural nosocomial infections and less often after endovascular aneurysm repair (EVAR)...
Medicare and bariatric surgeryJohn G Kral
American Society for Bariatric Surgery, Gainesville, Florida 32607, USA
Surg Obes Relat Dis 1:35-63. 2005
Processes and outcomes of care among navajo women with breast cancerDavid R Flum
JAMA 290:1996-7. 2003
Laparoscopic cholecystectomy safer than open? Administrative data gone astrayDavid R Flum
Am J Gastroenterol 99:1399. 2004
Prevalence and predictors of asymptomatic liver disease in patients undergoing gastric bypass surgeryCharles Beymer
Department of Internal Medicine, University of Washington School of Medicine, Seattle 98195-6410, USA
Arch Surg 138:1240-4. 2003..CONCLUSIONS: Moderate to severe hepatic steatosis and NASH are common among individuals undergoing gastric bypass procedures. Diabetes mellitus but not BMI is associated with NASH and advanced hepatic fibrosis in these patients...
The asymptomatic hernia: "if it's not broken, don't fix it"David R Flum
JAMA 295:328-9. 2006
Relationship of body mass index with demographic and clinical characteristics in the Longitudinal Assessment of Bariatric Surgery (LABS)Steven H Belle
Surg Obes Relat Dis 4:474-80. 2008..Outcomes analyses should consider the potential for the confounding of BMI with demographic and clinical characteristics...
Administrative data analyses in bariatric surgery--limits of the techniqueDavid R Flum
Surg Obes Relat Dis 2:78-81. 2006
Where is the captain of the ship when you need her?Michael A Goldfarb
Am Surg 72:1120-5; discussion 1126-48. 2006
Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric SurgerySteven H Belle
Data Coordinating Center, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
Surg Obes Relat Dis 3:116-26. 2007..To facilitate research in this field, the National Institute of Diabetes and Digestive and Kidney Diseases responded to this knowledge gap by establishing the Longitudinal Assessment of Bariatric Surgery (LABS) consortium...
Hematocrit level and postsurgical outcome: powers of observationFarhood Farjah
JAMA 297:2525-6. 2007
When not being superior may not be good enoughFarhood Farjah
JAMA 298:924-5. 2007
Gastrointestinal surgery as a treatment for diabetesDavid E Cummings
JAMA 299:341-3. 2008
Should cholecystectomy be performed for asymptomatic cholelithiasis in transplant patients?Lillian S Kao
Department of General Surgery, LBJ Hospital, University of Texas Houston Medical School, Houston, TX 77026, USA
J Am Coll Surg 197:302-12. 2003
Research Grants
- Bariatric Surgery Outcome/Cost in Medicare BeneficiariesDavid Flum; Fiscal Year: 2006..3. Perform a modeled cost effectiveness analysis of bariatric procedures compared to non-surgical approaches. ..
- Bariatric Surgery Research ConsortiumDavid Flum; Fiscal Year: 2007..Lastly the study will begin to evaluate the relationship of PYY3-36 and ghrelin and determine if it is altered by or in response to the physiologic changes associated with gastric bypass. ..
- Mechanisms of Glycemic Improvement Following Gastrointestinal SurgeryDavid Flum; Fiscal Year: 2009....
- Mechanisms of Glycemic Improvement Following Gastrointestinal SurgeryDAVID R contact FLUM; Fiscal Year: 2010....
- Surgical Care and Outcomes Assessment Program Comparative Effectiveness ResearchDavid R Flum; Fiscal Year: 2010..Surgical and interventional services span the continuum of healthcare conditions and SCOAP CERTN will have immediate capacity for investigators interested in almost any of AHRQ's priority conditions. ..
