A E Fleckenstein

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. ncbi request reprint Differential effects of psychostimulants and related agents on dopaminergic and serotonergic transporter function
    A E Fleckenstein
    Department of Pharmacology and Toxicology, University of Utah, 30 South 2000 East Rm 201, Salt Lake City, UT, USA
    Eur J Pharmacol 382:45-9. 1999
  2. ncbi request reprint Methamphetamine-induced rapid and reversible reduction in the activities of tryptophan hydroxylase and dopamine transporters: oxidative consequences?
    G R Hanson
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City 84112, USA
    Ann N Y Acad Sci 844:103-7. 1998
  3. ncbi request reprint Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model
    V Sandoval
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, USA
    J Neurosci 21:1413-9. 2001
  4. ncbi request reprint Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity
    A E Fleckenstein
    Department of Pharmacology and Toxicology, University of Utah, 30 South 2000 East, Rm 201, Salt Lake City, UT 84112, USA
    Eur J Pharmacol 406:1-13. 2000
  5. ncbi request reprint Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants
    J M Brown
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, USA
    J Pharmacol Exp Ther 296:762-7. 2001
  6. ncbi request reprint Cocaine-induced increases in vesicular dopamine uptake: role of dopamine receptors
    J M Brown
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, USA
    J Pharmacol Exp Ther 298:1150-3. 2001

Collaborators

  • G R Hanson
  • J M Brown
  • V Sandoval
  • Y V Ugarte
  • E L Riddle
  • J W Gibb
  • R R Metzger
  • J M Kokoshka

Detail Information

Publications6

  1. ncbi request reprint Differential effects of psychostimulants and related agents on dopaminergic and serotonergic transporter function
    A E Fleckenstein
    Department of Pharmacology and Toxicology, University of Utah, 30 South 2000 East Rm 201, Salt Lake City, UT, USA
    Eur J Pharmacol 382:45-9. 1999
    ..These findings demonstrate heretofore-unreported differences in the effects of these agents on monoamine transporter function, and a distinction between drug effects after direct application in vitro vs. administration in vivo...
  2. ncbi request reprint Methamphetamine-induced rapid and reversible reduction in the activities of tryptophan hydroxylase and dopamine transporters: oxidative consequences?
    G R Hanson
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City 84112, USA
    Ann N Y Acad Sci 844:103-7. 1998
    ..These findings suggest that there also may be other cellular elements similarly altered by METH treatment due to oxidative mechanisms...
  3. ncbi request reprint Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model
    V Sandoval
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, USA
    J Neurosci 21:1413-9. 2001
    ..Together, these data demonstrate that the in vitro incubation model mimics the rapid and reversible effects observed after a single METH injection...
  4. ncbi request reprint Differential effects of stimulants on monoaminergic transporters: pharmacological consequences and implications for neurotoxicity
    A E Fleckenstein
    Department of Pharmacology and Toxicology, University of Utah, 30 South 2000 East, Rm 201, Salt Lake City, UT 84112, USA
    Eur J Pharmacol 406:1-13. 2000
    ..Hence, this review will describe recent ex vivo studies investigating the rapid and differential affects of several stimulants on both plasmalemmal and vesicular monoamine transporter function...
  5. ncbi request reprint Regulation of the vesicular monoamine transporter-2: a novel mechanism for cocaine and other psychostimulants
    J M Brown
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, USA
    J Pharmacol Exp Ther 296:762-7. 2001
    ..Hence, the VMAT-2 may be an important target for developing strategies to treat not only cocaine addiction but also other disorders involving alterations in neuronal DA disposition, including Parkinson's disease...
  6. ncbi request reprint Cocaine-induced increases in vesicular dopamine uptake: role of dopamine receptors
    J M Brown
    Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah 84112, USA
    J Pharmacol Exp Ther 298:1150-3. 2001
    ..Furthermore, results indicate that D(2) receptor activation, per se, is sufficient to increase vesicular DA uptake...