David E Fleck

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi request reprint Factors associated with medication adherence in African American and white patients with bipolar disorder
    David E Fleck
    Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:646-52. 2005
  2. pmc A longitudinal functional connectivity analysis of the amygdala in bipolar I disorder across mood states
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 14:175-84. 2012
  3. pmc Characterizing impulsivity in mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
    Bipolar Disord 11:41-51. 2009
  4. ncbi request reprint Ethnicity and first-rank symptoms in patients with psychosis
    Lesley M Arnold
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Schizophr Res 67:207-12. 2004
  5. ncbi request reprint Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 2341 Albert Sabin Way, Cincinnati, OH 45267, USA
    Arch Gen Psychiatry 64:57-64. 2007
  6. pmc Impulsivity across the course of bipolar disorder
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0583, Cincinnati, OH 45267 0583, USA
    Bipolar Disord 12:285-97. 2010
  7. pmc Preliminary evidence for increased frontosubcortical activation on a motor impulsivity task in mixed episode bipolar disorder
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
    J Affect Disord 133:333-9. 2011
  8. pmc Cigarette smoking and impulsivity in bipolar disorder
    Jaimee L Heffner
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
    Bipolar Disord 14:735-42. 2012
  9. doi request reprint Differential brain activation during response inhibition in bipolar and attention-deficit hyperactivity disorders
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry, and The Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Early Interv Psychiatry 3:189-97. 2009
  10. pmc Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition task
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, and the Centefor Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Early Interv Psychiatry 2:225-33. 2008

Detail Information

Publications36

  1. ncbi request reprint Factors associated with medication adherence in African American and white patients with bipolar disorder
    David E Fleck
    Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:646-52. 2005
    ..The purpose of this study was to examine rates of medication nonadherence, self-perceived reasons for nonadherence, and attitudes associated with non-adherence in these ethnic groups...
  2. pmc A longitudinal functional connectivity analysis of the amygdala in bipolar I disorder across mood states
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 14:175-84. 2012
    ..To further understand the role of the amygdala in the generation of mood symptoms, we used functional magnetic resonance imaging (fMRI) to examine a group of patients with bipolar I disorder longitudinally...
  3. pmc Characterizing impulsivity in mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Universtiy of Cincinnati College of Medicine, Cincinnati, OH, USA
    Bipolar Disord 11:41-51. 2009
    ....
  4. ncbi request reprint Ethnicity and first-rank symptoms in patients with psychosis
    Lesley M Arnold
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Schizophr Res 67:207-12. 2004
    ..These findings indicate that psychotic symptom presentation should be evaluated in the context of other symptoms (e.g., affective symptoms) in diagnostic assessments in order to prevent misdiagnoses of schizophrenia...
  5. ncbi request reprint Effects of co-occurring cannabis use disorders on the course of bipolar disorder after a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 2341 Albert Sabin Way, Cincinnati, OH 45267, USA
    Arch Gen Psychiatry 64:57-64. 2007
    ..Cannabis use disorders commonly co-occur in bipolar disorder; however, the effects of cannabis abuse on outcome have been minimally studied...
  6. pmc Impulsivity across the course of bipolar disorder
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0583, Cincinnati, OH 45267 0583, USA
    Bipolar Disord 12:285-97. 2010
    ..To determine whether abnormalities of impulse control persist across the course of bipolar disorder, thereby representing potential state markers and endophenotypes...
  7. pmc Preliminary evidence for increased frontosubcortical activation on a motor impulsivity task in mixed episode bipolar disorder
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0583, USA
    J Affect Disord 133:333-9. 2011
    ..The aim of this study was to examine whether the neural correlates of motor impulsivity are distinct in patients with mixed mania...
  8. pmc Cigarette smoking and impulsivity in bipolar disorder
    Jaimee L Heffner
    Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219, USA
    Bipolar Disord 14:735-42. 2012
    ..The goal of this study was to examine the association between impulsivity and the initiation or maintenance of smoking in bipolar disorder...
  9. doi request reprint Differential brain activation during response inhibition in bipolar and attention-deficit hyperactivity disorders
    Michael A Cerullo
    Division of Bipolar Disorders Research, Department of Psychiatry, and The Center for Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Early Interv Psychiatry 3:189-97. 2009
    ..In contrast, we hypothesized that bipolar subjects would show altered brain activation in regions responsible for emotionally homeostasis, including the striatum and amygdala...
  10. pmc Magnetic resonance imaging brain activation in first-episode bipolar mania during a response inhibition task
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, and the Centefor Imaging Research, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    Early Interv Psychiatry 2:225-33. 2008
    ..Impulsivity is common in bipolar disorder, especially during mania. Understanding the functional neuroanatomy of response inhibition, one component of impulsivity, might clarify the neural substrate of bipolar disorder...
  11. ncbi request reprint Outcome following a first manic episode: cross-national US and Taiwan comparison
    Stephen M Strakowski
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 9:820-7. 2007
    ..Therefore, the aim of this study was to identify differential and shared outcome predictors in first-episode manic bipolar patients in Cincinnati, OH, USA and Taipei, Taiwan...
  12. ncbi request reprint Effects of co-occurring alcohol abuse on the course of bipolar disorder following a first hospitalization for mania
    Stephen M Strakowski
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, 231 Albert Sabin Way ML0559, PO Box 670559, Cincinnati, OH 45267 0559, USA
    Arch Gen Psychiatry 62:851-8. 2005
    ..Alcohol-use disorders are common co-occurring conditions affecting bipolar patients, and this co-occurrence is negatively associated with outcome...
  13. ncbi request reprint Sex, ethnicity, and antipsychotic medication use in patients with psychosis
    Lesley M Arnold
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH 45267 0559, USA
    Schizophr Res 66:169-75. 2004
    ..There were no ethnic or sex differences in the dosing of antipsychotics for the treatment of schizophrenia spectrum disorders. There were also no ethnic or sex differences in the use of second-generation antipsychotics...
  14. ncbi request reprint Rates, types, and psychosocial correlates of legal charges in adolescents with newly diagnosed bipolar disorder
    Drew H Barzman
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, OH 45229 3039, USA
    Bipolar Disord 9:339-44. 2007
    ..To examine the rates, types, and psychosocial correlates of legal charges in adolescents with newly diagnosed bipolar disorder (BD)...
  15. pmc Inhibition and attention in adolescents with nonmanic mood disorders and a high risk for developing mania
    Manpreet K Singh
    Department of Psychiatry, Division of Bipolar Disorders Research, University of Cincinnati, Cincinnati, OH, USA
    J Clin Exp Neuropsychol 31:1-7. 2009
    ..75), and color naming speed (d = 0.88). The results indicate that MD participants exhibit psychomotor disinhibition, marginal cognitive slowing and cautious response biases, but no formal deficits in sustained or selective attention...
  16. ncbi request reprint Twelve-month outcome of adolescents with bipolar disorder following first hospitalization for a manic or mixed episode
    Melissa P DelBello
    Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Am J Psychiatry 164:582-90. 2007
    ..The aim of this study was to examine the 12-month outcome of bipolar adolescents following an initial hospitalization for a manic or mixed episode...
  17. ncbi request reprint Ethnicity and diagnosis in patients with affective disorders
    Stephen M Strakowski
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
    J Clin Psychiatry 64:747-54. 2003
    ..Why this occurs is unknown. Extending prior work, the authors hypothesized that first-rank symptoms distract clinicians so that they fail to identify affective disorders in African Americans...
  18. pmc Functional magnetic resonance imaging brain activation in bipolar mania: evidence for disruption of the ventrolateral prefrontal-amygdala emotional pathway
    Stephen M Strakowski
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559 USA
    Biol Psychiatry 69:381-8. 2011
    ..We used functional magnetic resonance imaging (fMRI) to study manic bipolar subjects as they performed a cognitive task designed to examine the ventrolateral prefrontal emotional arousal network...
  19. doi request reprint Cigarette smoking in the early course of bipolar disorder: association with ages-at-onset of alcohol and marijuana use
    Jaimee L Heffner
    Tri State Tobacco and Alcohol Research Center, University of Cincinnati Genome Research Institute, Cincinnati, OH 45237, USA
    Bipolar Disord 10:838-45. 2008
    ..e., three or more times per week for a month or more)...
  20. pmc Conflict monitoring and adaptation in individuals at familial risk for developing bipolar disorder
    Luis R Patino
    Division of Bipolar Disorders Research, Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH 45219 0516, USA
    Bipolar Disord 15:264-71. 2013
    ..To examine conflict monitoring and conflict-driven adaptation in individuals at familial risk for developing bipolar disorder...
  21. pmc Impulsivity in adolescents with bipolar disorder and/or attention-deficit/hyperactivity disorder and healthy controls as measured by the Barratt Impulsiveness Scale
    Jayasree J Nandagopal
    Department of Psychiatry, University of Cincinnati, Cincinnati, Ohio 45267 0559, USA
    J Child Adolesc Psychopharmacol 21:465-8. 2011
    ....
  22. ncbi request reprint Differential prescription of maintenance antipsychotics to African American and white patients with new-onset bipolar disorder
    David E Fleck
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Clin Psychiatry 63:658-64. 2002
    ..African American patients may be at increased risk because excess antipsychotic prescription appears to be common in this population, although this issue has not been longitudinally studied in bipolar disorder...
  23. ncbi request reprint Processing efficiency and sustained attention in bipolar disorder
    David E Fleck
    Center for Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    J Int Neuropsychol Soc 11:49-57. 2005
    ..Problems with processing efficiency are viewed as trait characteristics of bipolar disorder that may be overlooked by traditional error-based assessments...
  24. ncbi request reprint Processing efficiency and directed forgetting in bipolar disorder
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Int Neuropsychol Soc 11:871-80. 2005
    ..Problems with processing efficiency are viewed as trait characteristics of bipolar disorder that may be overlooked by traditional error-based assessments...
  25. ncbi request reprint Risk and protective factors associated with substance use disorders in adolescents with first-episode mania
    Jacob R Stephens
    Research, Observation, Service, Education ROSE Program and the Division of Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, OH
    J Am Acad Child Adolesc Psychiatry 53:771-9. 2014
    ..The purpose of this study was to identify predictors of developing SUDs after a first manic episode...
  26. ncbi request reprint Post-traumatic stress symptoms and trauma exposure in youth with first episode bipolar disorder
    Jeffrey R Strawn
    Department of Psychiatry, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0559, USA
    Early Interv Psychiatry 4:169-73. 2010
    ..To examine the prevalence of trauma exposure as well as the rates and effects of post-traumatic stress disorder (PTSD) in adolescents with bipolar disorder following a first manic episode...
  27. ncbi request reprint Verbal memory in mania: effects of clinical state and task requirements
    David E Fleck
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 5:375-80. 2003
    ..Manic patients exhibit impaired verbal learning and memory, particularly following longstanding illness. However, it is unclear whether recognition and recall performance are differentially influenced by a manic mood state...
  28. ncbi request reprint The effectiveness and tolerability of aripiprazole for pediatric bipolar disorders: a retrospective chart review
    Drew H Barzman
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267, USA
    J Child Adolesc Psychopharmacol 14:593-600. 2004
    ..The aim of this retrospective chart review was to evaluate the effectiveness and tolerability of aripiprazole for the treatment of children and adolescents with bipolar disorders...
  29. ncbi request reprint Concurrent tracking of alcohol use and bipolar disorder symptoms
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Bipolar Disord 8:338-44. 2006
    ..The primary aim of this analysis was to examine concurrent symptom tracking and how the relative onsets of AUD and BD influence the concurrent tracking of symptoms...
  30. doi request reprint Wisconsin Card Sorting Test performance in bipolar disorder: effects of mood state and early course
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    Bipolar Disord 10:539-45. 2008
    ..However, it is unclear to what extent executive dysfunction exists (i) during syndromal remission, when mood symptoms are attenuated, and (ii) during the early course of bipolar disorder...
  31. doi request reprint The role of complex emotions in inconsistent diagnoses of schizophrenia
    Michael A Gara
    Department of Psychiatry, UMDNJ University Behavioral HealthCare and Robert Wood Johnson Medical School, Piscataway, NJ 08855 1392, USA
    J Nerv Ment Dis 198:609-13. 2010
    ..e., age of patient, gender, or ethnicity. In particular, complex emotion patterns were associated with greater disagreement between experts and trained lay interviewers than were simpler patterns...
  32. ncbi request reprint Safety and tolerability of quetiapine in the treatment of acute mania in bipolar disorder
    Caleb M Adler
    Center for Bipolar Disorders Research, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Affect Disord 100:S15-22. 2007
    ..To review the safety/tolerability of quetiapine in four placebo-controlled studies in patients with bipolar I disorder experiencing acute mania...
  33. doi request reprint Morphometric magnetic resonance imaging in psychiatry
    David E Fleck
    Division of Bipolar Disorders Research, Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45267 0559, USA
    Top Magn Reson Imaging 19:131-42. 2008
    ..However, advances in outcome and treatment monitoring show considerably more promise for rapid application in psychiatry...
  34. ncbi request reprint Inhibitory control in Obsessive-Compulsive Disorder
    Robert Krikorian
    Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Brain Cogn 54:257-9. 2004
    ..It was speculated, however, that emotional stimulation might negatively affect performance and that this might be studied in subsequent research...
  35. ncbi request reprint Neuroanatomic characterization of schizoaffective disorder using MRI: a pilot study
    Glen E Getz
    Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0559, USA
    Schizophr Res 55:55-9. 2002
    ..Patients diagnosed with SCA exhibited regional abnormalities on the striatum that resemble those seen in BPD. This study suggests that SCA has some neuroanatomical characteristics similar to BPD...
  36. ncbi request reprint Selective attention in schizoaffective disorder: pilot data
    David E Fleck
    Schizophr Res 68:109-10. 2004