Research Topics
| M L FlahertySummaryAffiliation: University of Cincinnati Country: USA Publications
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Detail Information
Publications
Carotid artery stenosis as a cause of strokeMatthew L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
Neuroepidemiology 40:36-41. 2013..We determined the types of large-vessel atherosclerosis responsible for ischemic strokes in a population-based stroke study...
The practice of carotid revascularization in a large metropolitan populationMatthew L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
J Stroke Cerebrovasc Dis 22:143-8. 2013..Point estimates for perioperative risk after CEA were improved from previous studies but remained above the recommended benchmarks. The number of CAS procedures was low, but the perioperative risk was significant...- Genome screen in familial intracranial aneurysmTatiana Foroud
Indiana University School of Medicine, Indianapolis, IN, USA
BMC Med Genet 10:3. 2009..Individuals with 1st degree relatives harboring an intracranial aneurysm (IA) are at an increased risk of IA, suggesting genetic variation is an important risk factor... - Anticoagulant-associated intracerebral hemorrhageMatthew L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
Semin Neurol 30:565-72. 2010..Surgical treatment of intracranial hemorrhage may be life saving in select cases, but has not reduced morbidity or mortality in large randomized trials... - The challenge of designing a treatment trial for warfarin-associated intracerebral hemorrhageMatthew L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
Stroke 40:1738-42. 2009..We determined the number of patients that would be eligible for enrollment in hypothetical treatment trials for WICH using a population-based study... - Warfarin use leads to larger intracerebral hematomasM L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
Neurology 71:1084-9. 2008..In a retrospective study, we sought to determine whether warfarin use is associated with larger initial hematoma volume, one determinant of mortality after ICH... - How important is surrogate consent for stroke research?M L Flaherty
Department of Neurology, University of Cincinnati Academic Health Center, 260 Stetson St, Room 2316, Cincinnati, OH 45267 0525, USA
Neurology 71:1566-71. 2008.... 
Location and outcome of anticoagulant-associated intracerebral hemorrhageMatthew L Flaherty
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Neurocrit Care 5:197-201. 2006..The characteristics of patients with anticoagulant-associated intracerebral hemorrhage (AAICH) have not been well characterized in a population-based setting...- The increasing incidence of anticoagulant-associated intracerebral hemorrhageM L Flaherty
Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
Neurology 68:116-21. 2007..To define temporal trends in the incidence of anticoagulant-associated intracerebral hemorrhage (AAICH) during the 1990s and relate them to rates of cardioembolic ischemic stroke... - Long-term mortality after intracerebral hemorrhageM L Flaherty
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Neurology 66:1182-6. 2006..To characterize long-term mortality following intracerebral hemorrhage (ICH) in two large population-based cohorts assembled more than a decade apart... - Combined IV and intra-arterial thrombolysis for acute ischemic strokeM L Flaherty
Department of Neurology, University of Cincinnati Medical Center, 231 Albert Sabin Way, MSB Rm 5161B, Cincinnati, OH, 45267 0525, USA
Neurology 64:386-8. 2005..Three-month modified Rankin Scale scores were 0 to 2 for 50% of patients, mortality was 18%, and symptomatic intracerebral hemorrhage occurred in 8%. IV/IA thrombolysis appeared safe and effective in this group... - Racial variations in location and risk of intracerebral hemorrhageMatthew L Flaherty
Department of Neurology, University of Cincinnati Medical Center, Ohio 45267 0525, USA
Stroke 36:934-7. 2005..Incidence rates of ICH are known to be higher in American blacks than whites, but how rates may differ by hemorrhage location is unknown. We sought to define incidence rates for different ICH locations in a biracial population... - Potential applicability of recombinant factor VIIa for intracerebral hemorrhageMatthew L Flaherty
Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Stroke 36:2660-4. 2005..We sought to determine the potential applicability of rFVIIa in a large, population-based cohort of ICH patients... - Population-based study of wake-up strokesJ Mackey
University of Cincinnati, Department of Neurology, Cincinnati, OH 45219, USA
Neurology 76:1662-7. 2011..We sought to establish the proportion and event rate of wake-up strokes in a large population-based study and to compare patients who awoke with stroke symptoms with those who were awake at time of onset... - Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic reviewB B Thompson
Department of Neurology, Brown University, Providence, RI, USA
Neurology 75:1333-42. 2010..We performed a systematic review and meta-analysis to address the hypothesis that pre-ICH APT use is associated with mortality and poor functional outcome following ICH... - Which stroke symptoms prompt a 911 call? A population-based studyDawn Kleindorfer
Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
Am J Emerg Med 28:607-12. 2010..Most studies have found that less than half of stroke/transient ischemic attack (TIA) events result in a 911 call. We sought to determine which symptoms prompt the public to call 911... - Greater rupture risk for familial as compared to sporadic unruptured intracranial aneurysmsJoseph P Broderick
Department of Neurology, Center for Stroke and Cerebrovascular Disease, University of Cincinnati Neuroscience Institute, UC College of Medicine, 260 Stetson Street, Cincinnati, OH 45267 0525, USA
Stroke 40:1952-7. 2009..The risk of intracranial aneurysm (IA) rupture in asymptomatic members of families who have multiple affected individuals is not known... - Emergency medical services use by stroke patients: a population-based studyOpeolu Adeoye
Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
Am J Emerg Med 27:141-5. 2009..In an epidemiological study, we determined the proportion of stroke patients who used EMS, hypothesizing that demographics, stroke severity, stroke type, and location at stroke onset would be associated with EMS use... - Temporal trends in public awareness of stroke: warning signs, risk factors, and treatmentDawn Kleindorfer
Department of Neurology, University of Cincinnati, Cincinnati, OH 45267, USA
Stroke 40:2502-6. 2009..We describe public knowledge of t-PA as a treatment for IS, as well as changes over time in knowledge of stroke warning signs (WS) and risk factors (RF)... - Clinical prediction of functional outcome after ischemic stroke: the surprising importance of periventricular white matter disease and raceBrett Kissela
Department of Neurology, University of Cincinnati, Ohio, USA
Stroke 40:530-6. 2009.... - Surgical management and case-fatality rates of intracerebral hemorrhage in 1988 and 2005Opeolu Adeoye
Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
Neurosurgery 63:1113-7; discussion 1117-8. 2008..To compare surgical management and case-fatality rates of intracerebral hemorrhage (ICH) in 1988 and 2005... - Population-based study of symptomatic internal carotid artery occlusion: incidence and long-term follow-upMatthew L Flaherty
Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Stroke 35:e349-52. 2004..Better strategies are needed to reduce early stroke recurrence in this setting... - Community socioeconomic status and prehospital times in acute stroke and transient ischemic attack: do poorer patients have longer delays from 911 call to the emergency department?Dawn O Kleindorfer
Department of Neurology, The Institute for the Study of Health, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
Stroke 37:1508-13. 2006..We examined the effect of socioeconomic status on prehospital delays in stroke and transient ischemic attack (TIA) patients within a large, biracial population... - Eligibility for the surgical trial in intracerebral hemorrhage II study in a population-based cohortOpeolu Adeoye
Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
Neurocrit Care 9:237-41. 2008..We sought to determine how many patients in a population-based ICH cohort would have been eligible for surgery using the Surgical Trial in Intracerebral Hemorrhage II (STICH II) criteria... - How much would performing diffusion-weighted imaging for all transient ischemic attacks increase MRI utilization?Opeolu Adeoye
Departments of Emergency Medicine and Neurosurgery, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
Stroke 41:2218-22. 2010..We determined how frequently MRI/DWI was performed for TIA and ascertained the proportion of clinically defined TIA patients who had ischemic lesions on DWI in our community in 2005... - Emergency department arrival times after acute ischemic stroke during the 1990sDawn O Kleindorfer
University of Cincinnati Medical Center, 231 Albert Sabin Way, MSB Room 5059A, Cincinnati, OH 45267 0525, USA
Neurocrit Care 7:31-5. 2007..We sought to investigate whether patients are arriving to the ED more quickly in 1999 than in 1993/94 within our large biracial population of 1.3 million... - Impact of socioeconomic status on stroke incidence: a population-based studyDawn O Kleindorfer
Department of Neurology, University of Cincinnati, Cincinnati, OH, USA
Ann Neurol 60:480-4. 2006 - Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke StudyDawn O Kleindorfer
Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45242, USA
Stroke 41:1326-31. 2010..The objective of this study was to examine temporal trends in stroke incidence and case-fatality within a large biracial population over time by comparing stroke incidence rates from 1993 to 1994, 1999, and 2005... - Smoking and family history and risk of aneurysmal subarachnoid hemorrhageD Woo
Department of Neurology, University of Cincinnati College of Medicine, 260 Stetson Street ML 0525, Cincinnati, OH 45267 0525, USA
Neurology 72:69-72. 2009..Using a population-based case-control study of hemorrhagic stroke, we hypothesized that having both a first-degree relative with a brain aneurysm or SAH (+FH) and current smoking interact to increase the risk of aSAH... - The relationship between smoking and replicated sequence variants on chromosomes 8 and 9 with familial intracranial aneurysmRanjan Deka
Department of Neurology, UC Neuroscience Institute, University of Cincinnati Academic Health Center, 260 Stetson Street, Suite 2300, PO Box 670525, Cincinnati, OH 45267 0525, USA
Stroke 41:1132-7. 2010..The purpose of this study was to replicate the previous association of single nucleotide polymorphisms (SNPs) with risk of intracranial aneurysm (IA) and to examine the relationship of smoking with these variants and the risk of IA... - False-negative diffusion-weighted imaging with lateral medullary infarctionRakesh Khatri
Departments of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0525, USA
Neurology 67:E19. 2006 - Designing a message for public education regarding stroke: does FAST capture enough stroke?Dawn O Kleindorfer
Stroke 38:2864-8. 2007..We sought to assess the percentage of stroke/transient ischemic attack (TIA) patients identified by both public awareness messages by examining presenting symptoms of all stroke/TIA patients from a large, biracial population in 1999... - Critical pathways for the management of stroke and intracerebral hemorrhage: a survey of US hospitalsDavid Cooper
Department of Medical Affairs, Novo Nordisk Inc, Princeton, NJ 08540, USA
Crit Pathw Cardiol 6:18-23. 2007..Similar to acute ischemic stroke care, proper preparation and role definition will be critical for efficient evaluation and treatment. We studied the existence and structure of ICH management protocols in US hospitals... - Mortality of stroke patients treated with thrombolysis: analysis of nationwide inpatient sampleMatthew L Flaherty
Neurology 68:710-1; author reply 711. 2007 - The incidence of deep and lobar intracerebral hemorrhage in whites, blacks, and HispanicsMatthew L Flaherty
Neurology 66:956-7; author reply 956-7. 2006 - The role of race in time to treatment after subarachnoid hemorrhageSonia V Eden
Neurosurgery 60:837-43; discussion 837-43. 2007..05). CONCLUSION: Race was not associated with time to treatment after aneurysmal SAH in the Greater Cincinnati area. Reducing the increased burden of SAH mortality among blacks must be addressed at the prevention stage... - ESPRIT trialMatthew L Flaherty
Lancet 368:448; author reply 449. 2006