M L Flaherty

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. pmc Carotid artery stenosis as a cause of stroke
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Neuroepidemiology 40:36-41. 2013
  2. pmc The practice of carotid revascularization in a large metropolitan population
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    J Stroke Cerebrovasc Dis 22:143-8. 2013
  3. pmc Genome screen in familial intracranial aneurysm
    Tatiana Foroud
    Indiana University School of Medicine, Indianapolis, IN, USA
    BMC Med Genet 10:3. 2009
  4. doi request reprint Anticoagulant-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Semin Neurol 30:565-72. 2010
  5. pmc The challenge of designing a treatment trial for warfarin-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Stroke 40:1738-42. 2009
  6. pmc Warfarin use leads to larger intracerebral hematomas
    M L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
    Neurology 71:1084-9. 2008
  7. doi request reprint How important is surrogate consent for stroke research?
    M L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, 260 Stetson St, Room 2316, Cincinnati, OH 45267 0525, USA
    Neurology 71:1566-71. 2008
  8. ncbi request reprint Location and outcome of anticoagulant-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Neurocrit Care 5:197-201. 2006
  9. ncbi request reprint The increasing incidence of anticoagulant-associated intracerebral hemorrhage
    M L Flaherty
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Neurology 68:116-21. 2007
  10. ncbi request reprint Long-term mortality after intracerebral hemorrhage
    M L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Neurology 66:1182-6. 2006

Detail Information

Publications37

  1. pmc Carotid artery stenosis as a cause of stroke
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Neuroepidemiology 40:36-41. 2013
    ..We determined the types of large-vessel atherosclerosis responsible for ischemic strokes in a population-based stroke study...
  2. pmc The practice of carotid revascularization in a large metropolitan population
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    J Stroke Cerebrovasc Dis 22:143-8. 2013
    ..Point estimates for perioperative risk after CEA were improved from previous studies but remained above the recommended benchmarks. The number of CAS procedures was low, but the perioperative risk was significant...
  3. pmc Genome screen in familial intracranial aneurysm
    Tatiana Foroud
    Indiana University School of Medicine, Indianapolis, IN, USA
    BMC Med Genet 10:3. 2009
    ..Individuals with 1st degree relatives harboring an intracranial aneurysm (IA) are at an increased risk of IA, suggesting genetic variation is an important risk factor...
  4. doi request reprint Anticoagulant-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Semin Neurol 30:565-72. 2010
    ..Surgical treatment of intracranial hemorrhage may be life saving in select cases, but has not reduced morbidity or mortality in large randomized trials...
  5. pmc The challenge of designing a treatment trial for warfarin-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, Ohio 45267 0525, USA
    Stroke 40:1738-42. 2009
    ..We determined the number of patients that would be eligible for enrollment in hypothetical treatment trials for WICH using a population-based study...
  6. pmc Warfarin use leads to larger intracerebral hematomas
    M L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, Cincinnati, OH 45267 0525, USA
    Neurology 71:1084-9. 2008
    ..In a retrospective study, we sought to determine whether warfarin use is associated with larger initial hematoma volume, one determinant of mortality after ICH...
  7. doi request reprint How important is surrogate consent for stroke research?
    M L Flaherty
    Department of Neurology, University of Cincinnati Academic Health Center, 260 Stetson St, Room 2316, Cincinnati, OH 45267 0525, USA
    Neurology 71:1566-71. 2008
    ....
  8. ncbi request reprint Location and outcome of anticoagulant-associated intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Neurocrit Care 5:197-201. 2006
    ..The characteristics of patients with anticoagulant-associated intracerebral hemorrhage (AAICH) have not been well characterized in a population-based setting...
  9. ncbi request reprint The increasing incidence of anticoagulant-associated intracerebral hemorrhage
    M L Flaherty
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Neurology 68:116-21. 2007
    ..To define temporal trends in the incidence of anticoagulant-associated intracerebral hemorrhage (AAICH) during the 1990s and relate them to rates of cardioembolic ischemic stroke...
  10. ncbi request reprint Long-term mortality after intracerebral hemorrhage
    M L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Neurology 66:1182-6. 2006
    ..To characterize long-term mortality following intracerebral hemorrhage (ICH) in two large population-based cohorts assembled more than a decade apart...
  11. ncbi request reprint Combined IV and intra-arterial thrombolysis for acute ischemic stroke
    M L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, 231 Albert Sabin Way, MSB Rm 5161B, Cincinnati, OH, 45267 0525, USA
    Neurology 64:386-8. 2005
    ..Three-month modified Rankin Scale scores were 0 to 2 for 50% of patients, mortality was 18%, and symptomatic intracerebral hemorrhage occurred in 8%. IV/IA thrombolysis appeared safe and effective in this group...
  12. ncbi request reprint Racial variations in location and risk of intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Ohio 45267 0525, USA
    Stroke 36:934-7. 2005
    ..Incidence rates of ICH are known to be higher in American blacks than whites, but how rates may differ by hemorrhage location is unknown. We sought to define incidence rates for different ICH locations in a biracial population...
  13. ncbi request reprint Potential applicability of recombinant factor VIIa for intracerebral hemorrhage
    Matthew L Flaherty
    Department of Neurology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Stroke 36:2660-4. 2005
    ..We sought to determine the potential applicability of rFVIIa in a large, population-based cohort of ICH patients...
  14. pmc Population-based study of wake-up strokes
    J Mackey
    University of Cincinnati, Department of Neurology, Cincinnati, OH 45219, USA
    Neurology 76:1662-7. 2011
    ..We sought to establish the proportion and event rate of wake-up strokes in a large population-based study and to compare patients who awoke with stroke symptoms with those who were awake at time of onset...
  15. pmc Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review
    B B Thompson
    Department of Neurology, Brown University, Providence, RI, USA
    Neurology 75:1333-42. 2010
    ..We performed a systematic review and meta-analysis to address the hypothesis that pre-ICH APT use is associated with mortality and poor functional outcome following ICH...
  16. pmc Which stroke symptoms prompt a 911 call? A population-based study
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati, Cincinnati, OH 45267 0525, USA
    Am J Emerg Med 28:607-12. 2010
    ..Most studies have found that less than half of stroke/transient ischemic attack (TIA) events result in a 911 call. We sought to determine which symptoms prompt the public to call 911...
  17. pmc Greater rupture risk for familial as compared to sporadic unruptured intracranial aneurysms
    Joseph P Broderick
    Department of Neurology, Center for Stroke and Cerebrovascular Disease, University of Cincinnati Neuroscience Institute, UC College of Medicine, 260 Stetson Street, Cincinnati, OH 45267 0525, USA
    Stroke 40:1952-7. 2009
    ..The risk of intracranial aneurysm (IA) rupture in asymptomatic members of families who have multiple affected individuals is not known...
  18. pmc Emergency medical services use by stroke patients: a population-based study
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Am J Emerg Med 27:141-5. 2009
    ..In an epidemiological study, we determined the proportion of stroke patients who used EMS, hypothesizing that demographics, stroke severity, stroke type, and location at stroke onset would be associated with EMS use...
  19. pmc Temporal trends in public awareness of stroke: warning signs, risk factors, and treatment
    Dawn Kleindorfer
    Department of Neurology, University of Cincinnati, Cincinnati, OH 45267, USA
    Stroke 40:2502-6. 2009
    ..We describe public knowledge of t-PA as a treatment for IS, as well as changes over time in knowledge of stroke warning signs (WS) and risk factors (RF)...
  20. pmc Clinical prediction of functional outcome after ischemic stroke: the surprising importance of periventricular white matter disease and race
    Brett Kissela
    Department of Neurology, University of Cincinnati, Ohio, USA
    Stroke 40:530-6. 2009
    ....
  21. pmc Surgical management and case-fatality rates of intracerebral hemorrhage in 1988 and 2005
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
    Neurosurgery 63:1113-7; discussion 1117-8. 2008
    ..To compare surgical management and case-fatality rates of intracerebral hemorrhage (ICH) in 1988 and 2005...
  22. ncbi request reprint Population-based study of symptomatic internal carotid artery occlusion: incidence and long-term follow-up
    Matthew L Flaherty
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    Stroke 35:e349-52. 2004
    ..There are no previous population-based natural history studies evaluating outcome after symptomatic ICA occlusion (SICAO)...
  23. ncbi request reprint Community socioeconomic status and prehospital times in acute stroke and transient ischemic attack: do poorer patients have longer delays from 911 call to the emergency department?
    Dawn O Kleindorfer
    Department of Neurology, The Institute for the Study of Health, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Stroke 37:1508-13. 2006
    ..We examined the effect of socioeconomic status on prehospital delays in stroke and transient ischemic attack (TIA) patients within a large, biracial population...
  24. pmc Eligibility for the surgical trial in intracerebral hemorrhage II study in a population-based cohort
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
    Neurocrit Care 9:237-41. 2008
    ..We sought to determine how many patients in a population-based ICH cohort would have been eligible for surgery using the Surgical Trial in Intracerebral Hemorrhage II (STICH II) criteria...
  25. pmc How much would performing diffusion-weighted imaging for all transient ischemic attacks increase MRI utilization?
    Opeolu Adeoye
    Departments of Emergency Medicine and Neurosurgery, University of Cincinnati Medical Center, Cincinnati, OH 45267 0525, USA
    Stroke 41:2218-22. 2010
    ..We determined how frequently MRI/DWI was performed for TIA and ascertained the proportion of clinically defined TIA patients who had ischemic lesions on DWI in our community in 2005...
  26. ncbi request reprint Emergency department arrival times after acute ischemic stroke during the 1990s
    Dawn O Kleindorfer
    University of Cincinnati Medical Center, 231 Albert Sabin Way, MSB Room 5059A, Cincinnati, OH 45267 0525, USA
    Neurocrit Care 7:31-5. 2007
    ..We sought to investigate whether patients are arriving to the ED more quickly in 1999 than in 1993/94 within our large biracial population of 1.3 million...
  27. ncbi request reprint Impact of socioeconomic status on stroke incidence: a population-based study
    Dawn O Kleindorfer
    Department of Neurology, University of Cincinnati, Cincinnati, OH, USA
    Ann Neurol 60:480-4. 2006
  28. pmc Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke Study
    Dawn O Kleindorfer
    Department of Neurology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45242, USA
    Stroke 41:1326-31. 2010
    ..The objective of this study was to examine temporal trends in stroke incidence and case-fatality within a large biracial population over time by comparing stroke incidence rates from 1993 to 1994, 1999, and 2005...
  29. pmc Smoking and family history and risk of aneurysmal subarachnoid hemorrhage
    D Woo
    Department of Neurology, University of Cincinnati College of Medicine, 260 Stetson Street ML 0525, Cincinnati, OH 45267 0525, USA
    Neurology 72:69-72. 2009
    ..Using a population-based case-control study of hemorrhagic stroke, we hypothesized that having both a first-degree relative with a brain aneurysm or SAH (+FH) and current smoking interact to increase the risk of aSAH...
  30. pmc The relationship between smoking and replicated sequence variants on chromosomes 8 and 9 with familial intracranial aneurysm
    Ranjan Deka
    Department of Neurology, UC Neuroscience Institute, University of Cincinnati Academic Health Center, 260 Stetson Street, Suite 2300, PO Box 670525, Cincinnati, OH 45267 0525, USA
    Stroke 41:1132-7. 2010
    ..The purpose of this study was to replicate the previous association of single nucleotide polymorphisms (SNPs) with risk of intracranial aneurysm (IA) and to examine the relationship of smoking with these variants and the risk of IA...
  31. ncbi request reprint False-negative diffusion-weighted imaging with lateral medullary infarction
    Rakesh Khatri
    Departments of Neurology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0525, USA
    Neurology 67:E19. 2006
  32. ncbi request reprint Designing a message for public education regarding stroke: does FAST capture enough stroke?
    Dawn O Kleindorfer
    Stroke 38:2864-8. 2007
    ..We sought to assess the percentage of stroke/transient ischemic attack (TIA) patients identified by both public awareness messages by examining presenting symptoms of all stroke/TIA patients from a large, biracial population in 1999...
  33. ncbi request reprint Critical pathways for the management of stroke and intracerebral hemorrhage: a survey of US hospitals
    David Cooper
    Department of Medical Affairs, Novo Nordisk Inc, Princeton, NJ 08540, USA
    Crit Pathw Cardiol 6:18-23. 2007
    ..Similar to acute ischemic stroke care, proper preparation and role definition will be critical for efficient evaluation and treatment. We studied the existence and structure of ICH management protocols in US hospitals...
  34. ncbi request reprint Mortality of stroke patients treated with thrombolysis: analysis of nationwide inpatient sample
    Matthew L Flaherty
    Neurology 68:710-1; author reply 711. 2007
  35. ncbi request reprint The incidence of deep and lobar intracerebral hemorrhage in whites, blacks, and Hispanics
    Matthew L Flaherty
    Neurology 66:956-7; author reply 956-7. 2006
  36. ncbi request reprint The role of race in time to treatment after subarachnoid hemorrhage
    Sonia V Eden
    Neurosurgery 60:837-43; discussion 837-43. 2007
    ..The time to treatment for aneurysmal SAH has been found to correlate with mortality and outcome. Therefore, we examined racial differences in the time to treatment of aneurysmal SAH among patients from the Greater Cincinnati area...
  37. ncbi request reprint ESPRIT trial
    Matthew L Flaherty
    Lancet 368:448; author reply 449. 2006