Shelly B Flagel

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi request reprint Quantifying the psychomotor activating effects of cocaine in the rat
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, The University of Michigan, Ann Arbor, Michigan 48109 0720, USA
    Behav Pharmacol 18:297-302. 2007
  2. pmc A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions
    S B Flagel
    Department of Psychiatry, University of Michigan, AnnArbor, MI 48109, USA
    Neuroscience 196:80-96. 2011
  3. pmc An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 35:388-400. 2010
  4. pmc Individual differences in the attribution of incentive salience to reward-related cues: Implications for addiction
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropharmacology 56:139-48. 2009
  5. ncbi request reprint Individual differences in the propensity to approach signals vs goals promote different adaptations in the dopamine system of rats
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI, 48109 0720, USA
    Psychopharmacology (Berl) 191:599-607. 2007
  6. pmc Individual differences in the attribution of incentive salience to a reward-related cue: influence on cocaine sensitization
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, The University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI 48109, USA
    Behav Brain Res 186:48-56. 2008
  7. pmc Persistent alterations in cognitive function and prefrontal dopamine D2 receptors following extended, but not limited, access to self-administered cocaine
    Lisa A Briand
    Neuroscience Program, University of Michigan, Ann Arbor, MI, USA
    Neuropsychopharmacology 33:2969-80. 2008
  8. pmc A selective role for dopamine in stimulus-reward learning
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Michigan, USA
    Nature 469:53-7. 2011
  9. pmc Cocaine interacts with the novelty-seeking trait to modulate FGFR1 gene expression in the rat
    Cortney A Turner
    Molecular and Behavioral Neuroscience Institute, 205 Zina Pitcher Place, University of Michigan, Ann Arbor, MI 48109, USA
    Neurosci Lett 446:105-7. 2008
  10. ncbi request reprint Manipulations during the second, but not the first, week of life increase susceptibility to cocaine self-administration in female rats
    Shelly B Flagel
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 28:1741-51. 2003

Detail Information

Publications17

  1. ncbi request reprint Quantifying the psychomotor activating effects of cocaine in the rat
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, The University of Michigan, Ann Arbor, Michigan 48109 0720, USA
    Behav Pharmacol 18:297-302. 2007
    ..We report that the combination of these measures provides an especially sensitive measure of the psychomotor activating effects of cocaine, and how behavior changes as a consequence of repeated drug treatment...
  2. pmc A food predictive cue must be attributed with incentive salience for it to induce c-fos mRNA expression in cortico-striatal-thalamic brain regions
    S B Flagel
    Department of Psychiatry, University of Michigan, AnnArbor, MI 48109, USA
    Neuroscience 196:80-96. 2011
    ..These data suggest that the predictive value of a reward cue is not sufficient to engage brain reward systems-the cue must also be attributed with incentive salience...
  3. pmc An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 35:388-400. 2010
    ....
  4. pmc Individual differences in the attribution of incentive salience to reward-related cues: Implications for addiction
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropharmacology 56:139-48. 2009
    ..It will be important, therefore, to study how environmental, neurobiological and genetic interactions determine the extent to which individuals attribute incentive value to reward-predictive stimuli...
  5. ncbi request reprint Individual differences in the propensity to approach signals vs goals promote different adaptations in the dopamine system of rats
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI, 48109 0720, USA
    Psychopharmacology (Berl) 191:599-607. 2007
    ..The way an individual responds to cues associated with rewards may be a key determinant of vulnerability to compulsive behavioral disorders...
  6. pmc Individual differences in the attribution of incentive salience to a reward-related cue: influence on cocaine sensitization
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, The University of Michigan, 205 Zina Pitcher Place, Ann Arbor, MI 48109, USA
    Behav Brain Res 186:48-56. 2008
    ....
  7. pmc Persistent alterations in cognitive function and prefrontal dopamine D2 receptors following extended, but not limited, access to self-administered cocaine
    Lisa A Briand
    Neuroscience Program, University of Michigan, Ann Arbor, MI, USA
    Neuropsychopharmacology 33:2969-80. 2008
    ....
  8. pmc A selective role for dopamine in stimulus-reward learning
    Shelly B Flagel
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Michigan, USA
    Nature 469:53-7. 2011
    ..This work provides insight into the neurobiology of a form of stimulus-reward learning that confers increased susceptibility to disorders of impulse control...
  9. pmc Cocaine interacts with the novelty-seeking trait to modulate FGFR1 gene expression in the rat
    Cortney A Turner
    Molecular and Behavioral Neuroscience Institute, 205 Zina Pitcher Place, University of Michigan, Ann Arbor, MI 48109, USA
    Neurosci Lett 446:105-7. 2008
    ..These results suggest that cocaine interacts with the novelty-seeking trait to alter gene expression. Thus, the FGF system may contribute to individual differences in the response to drugs of abuse...
  10. ncbi request reprint Manipulations during the second, but not the first, week of life increase susceptibility to cocaine self-administration in female rats
    Shelly B Flagel
    Neuroscience Program, University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 28:1741-51. 2003
    ..We conclude that the second week of life in the rodent is a sensitive period during which manipulations result in a more vulnerable phenotype for the acquisition of cocaine SA...
  11. pmc Neonatal FGF2 alters cocaine self-administration in the adult rat
    Cortney A Turner
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Pharmacol Biochem Behav 92:100-4. 2009
    ..Thus, FGF2 may be an antecedent of vulnerability for drug-taking behavior and may provide clues to novel therapeutic approaches for the treatment of addiction...
  12. pmc Dissociating the predictive and incentive motivational properties of reward-related cues through the study of individual differences
    Terry E Robinson
    Biopsychology Program, Department of Psychology, University of Michigan, East Hall, 530 Church Street, Ann Arbor, MI 48109, USA
    Biol Psychiatry 65:869-73. 2009
    ..Thus, CSs can have both predictive and incentive properties. We ask here whether it is possible to dissociate the predictive versus incentive properties of a CS in rats by considering individual differences in the nature of the CR...
  13. pmc Quantifying individual variation in the propensity to attribute incentive salience to reward cues
    Paul J Meyer
    Department of Psychology, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 7:e38987. 2012
    ....
  14. pmc Decreased proliferation of adult hippocampal stem cells during cocaine withdrawal: possible role of the cell fate regulator FADD
    M Julia Garcia-Fuster
    Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA
    Neuropsychopharmacology 36:2303-17. 2011
    ....
  15. ncbi request reprint Effects of tapering neonatal dexamethasone on rat growth, neurodevelopment, and stress response
    Shelly B Flagel
    Department of Pediatrics, University of Michigan, Ann Arbor, Michigan 48109 0720, USA
    Am J Physiol Regul Integr Comp Physiol 282:R55-63. 2002
    ..This may lead to increased risk for learning impairment and maladaptive responses to the environment...
  16. pmc Risk-assessment and coping strategies segregate with divergent intrinsic aerobic capacity in rats
    Paul R Burghardt
    Molecular and Behavioral Neuroscience Institute, The University of Michigan, Ann Arbor, MI 48109, USA
    Neuropsychopharmacology 36:390-401. 2011
    ..Within this context, we propose that intrinsic aerobic capacity is a central feature mechanistically linking complex metabolic disease and behavior...
  17. pmc Cocaine self-administration produces a persistent increase in dopamine D2 High receptors
    Lisa A Briand
    Neuroscience Program, The University of Michigan, United States
    Eur Neuropsychopharmacol 18:551-6. 2008
    ..This may also help explain why stimuli that increase dopamine neurotransmission, including drugs themselves, are so effective in producing relapse in individuals with a history of exposure to cocaine...