David A Fishbain

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. ncbi Does pain cause the perception of fatigue in patients with chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, Florida, USA
    Pain Pract 9:354-62. 2009
  2. ncbi Pharmacotherapeutic management of breakthrough pain in patients with chronic persistent pain
    David A Fishbain
    Miller School of Medicine at the University of Miami, 304A Dominion Tower, 1400 NW 10th Ave, Miami, FL 33136, USA
    Am J Manag Care 14:S123-8. 2008
  3. ncbi Does pain mediate the pain interference with sleep problem in chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine
    David A Fishbain
    Departments of Psychiatry, Neurological Surgery and Anesthesiology, Miller School of Medicine, University of Miami, Miami, Florida, USA
    J Pain Symptom Manage 36:639-47. 2008
  4. ncbi Variables associated with current smoking status in chronic pain patients
    David A Fishbain
    University of Miami School of Medicine, Department of Psychiatry, Miami, Florida 33136, USA
    Pain Med 8:301-11. 2007
  5. ncbi Risk for five forms of suicidality in acute pain patients and chronic pain patients vs pain-free community controls
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, Florida, USA
    Pain Med 10:1095-105. 2009
  6. ncbi Medicolegal rounds: medicolegal issues and alleged breaches of standards of medical care in a patient motor vehicle accident allegedly related to chronic opioid analgesic therapy
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Florida, USA
    J Opioid Manag 3:16-20. 2007
  7. ncbi What percentage of chronic nonmalignant pain patients exposed to chronic opioid analgesic therapy develop abuse/addiction and/or aberrant drug-related behaviors? A structured evidence-based review
    David A Fishbain
    Miller School of Medicine at the University of Miami, Miami, Florida, USA
    Pain Med 9:444-59. 2008
  8. ncbi Alleged medical abandonment in chronic opioid analgesic therapy: case report
    David A Fishbain
    Departments of Psychiatry, Miller School of Medicine, University of Miami, 1400 Northwest 10th Avenue D 79, Miami, FL 33136, USA
    Pain Med 10:722-9. 2009
  9. ncbi Predictors of homicide-suicide affirmation in acute and chronic pain patients
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, 1400 NW 10th Avenue, Miami, FL 33136, USA
    Pain Med 12:127-37. 2011
  10. ncbi Variables associated with self-prediction of psychopharmacological treatment adherence in acute and chronic pain patients
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at University of Miami, Miami, Florida 33136, USA
    Pain Pract 10:508-19. 2010

Detail Information

Publications65

  1. ncbi Does pain cause the perception of fatigue in patients with chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, Florida, USA
    Pain Pract 9:354-62. 2009
    ..Thus, improvement of pain may be important in the context of trying to improve fatigue in DPNP patients...
  2. ncbi Pharmacotherapeutic management of breakthrough pain in patients with chronic persistent pain
    David A Fishbain
    Miller School of Medicine at the University of Miami, 304A Dominion Tower, 1400 NW 10th Ave, Miami, FL 33136, USA
    Am J Manag Care 14:S123-8. 2008
    ..This article reviews the types of BTP, the therapeutic options available to manage BTP, and the tools designed to detect and minimize the risk of aberrant drug-related behaviors potentially associated with opioid medications...
  3. ncbi Does pain mediate the pain interference with sleep problem in chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine
    David A Fishbain
    Departments of Psychiatry, Neurological Surgery and Anesthesiology, Miller School of Medicine, University of Miami, Miami, Florida, USA
    J Pain Symptom Manage 36:639-47. 2008
    ..Although this association cannot establish causality, these results provide some evidence for the possibility that pain may mediate the sleep problem associated with DPNP and perhaps chronic pain in general...
  4. ncbi Variables associated with current smoking status in chronic pain patients
    David A Fishbain
    University of Miami School of Medicine, Department of Psychiatry, Miami, Florida 33136, USA
    Pain Med 8:301-11. 2007
    ..Smoking may be a major problem in chronic pain patients (CPPs). The goal of this study was to determine if pain and psychiatric comorbidity are associated with smoking status in CPPs...
  5. ncbi Risk for five forms of suicidality in acute pain patients and chronic pain patients vs pain-free community controls
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, Florida, USA
    Pain Med 10:1095-105. 2009
    ..The objective of this study was to determine the risk for five forms of suicidality in rehabilitation acute pain patients (APPs) and rehabilitation chronic pain patients (CPPs) vs pain-free community controls...
  6. ncbi Medicolegal rounds: medicolegal issues and alleged breaches of standards of medical care in a patient motor vehicle accident allegedly related to chronic opioid analgesic therapy
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Florida, USA
    J Opioid Manag 3:16-20. 2007
    ..Based on these opinions, we have attempted to develop some recommendations on how pain physicians should approach the problem of deciding whether patients should be allowed to drive when on COAT...
  7. ncbi What percentage of chronic nonmalignant pain patients exposed to chronic opioid analgesic therapy develop abuse/addiction and/or aberrant drug-related behaviors? A structured evidence-based review
    David A Fishbain
    Miller School of Medicine at the University of Miami, Miami, Florida, USA
    Pain Med 9:444-59. 2008
    ....
  8. ncbi Alleged medical abandonment in chronic opioid analgesic therapy: case report
    David A Fishbain
    Departments of Psychiatry, Miller School of Medicine, University of Miami, 1400 Northwest 10th Avenue D 79, Miami, FL 33136, USA
    Pain Med 10:722-9. 2009
    ....
  9. ncbi Predictors of homicide-suicide affirmation in acute and chronic pain patients
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, 1400 NW 10th Avenue, Miami, FL 33136, USA
    Pain Med 12:127-37. 2011
    ....
  10. ncbi Variables associated with self-prediction of psychopharmacological treatment adherence in acute and chronic pain patients
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at University of Miami, Miami, Florida 33136, USA
    Pain Pract 10:508-19. 2010
    ..pain-free community controls and community patients, and (2) determine which variables predict nonadherence...
  11. ncbi Exploration of anger constructs in acute and chronic pain patients vs. community patients
    David A Fishbain
    Miller School of Medicine, University of Miami, FL 33136, USA
    Pain Pract 11:240-51. 2011
    ....
  12. ncbi Alleged breaches of "standards of medical care" in a patient overdose death possibly related to chronic opioid analgesic therapy, application of the controlled substances model guidelines: case report
    David A Fishbain
    Departments of Psychiatry, University of Miami, Miami, FL 33136, USA
    Pain Med 10:565-72. 2009
    ....
  13. ncbi Are patients with chronic low back pain or chronic neck pain fatigued?
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, Miami, Florida, USA
    Pain Med 5:187-95. 2004
    ..To the authors' knowledge, this is the first such study in the literature...
  14. ncbi Exploration of the relationship between disability perception, preference for death over disability, and suicidality in patients with acute and chronic pain
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at University of Miami, Miami, Florida 33136, USA
    Pain Med 13:552-61. 2012
    ..Passive, active, and historical suicidality are associated with preference for death over disability...
  15. ncbi A structured evidence-based review on the meaning of nonorganic physical signs: Waddell signs
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, Miami, Florida, USA
    Pain Med 4:141-81. 2003
    ..This is a structured, evidence-based review of all available studies addressing the concept of nonorganic findings: Waddell signs (WSs)...
  16. ncbi Medical malpractice allegations of iatrogenic addiction in chronic opioid analgesic therapy: forensic case reports
    David A Fishbain
    Department of Psychiatry, Miami Veterans Administration Hospital, Miami, Florida, USA
    Pain Med 11:1537-45. 2010
    ....
  17. ncbi Is there a relationship between nonorganic physical findings (Waddell signs) and secondary gain/malingering?
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, Miami Beach, FL, USA
    Clin J Pain 20:399-408. 2004
    ..The preponderance of the evidence points to the opposite: no association...
  18. ncbi Lidocaine 5% patch: an open-label naturalistic chronic pain treatment trial and prediction of response
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, 1400 NW 10th Avenue, D 79, Florida 33136, USA
    Pain Med 7:135-42. 2006
    ..The purpose of this report was to describe the results of a retrospective review of this open-label naturalistic L5P chronic pain treatment trial and to attempt to delineate predictors of perceived clinical response...
  19. ncbi Does smoking status affect multidisciplinary pain facility treatment outcome?
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at University of Miami, Florida 33136, USA
    Pain Med 9:1081-90. 2008
    ..Smoking may be a major problem in chronic low back pain (LBP) patients. The goal of this study was to determine whether smoking status affected multidisciplinary pain facility treatment outcome...
  20. ncbi What are the variables that are associated with the patient's wish to sue his physician in patients with acute and chronic pain?
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, Miami, Florida, USA
    Pain Med 9:1130-42. 2008
    ..The objective of this study was then to develop some statistical models that would describe such patients' attributes...
  21. ncbi Chronic pain and the measurement of personality: do states influence traits?
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, 1400 NW 10th Avenue, Miami, FL 33136, USA
    Pain Med 7:509-29. 2006
    ..This is a structured evidence-based review of all available studies on the effect of pain, (a state phenomenon) on the measurement of personality characteristics (a trait phenomenon)...
  22. ncbi Do the second-generation "atypical neuroleptics" have analgesic properties? A structured evidence-based review
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, 1400 NW 10th Avenue, Miami Beach, FL 33136, USA
    Pain Med 5:359-65. 2004
    ..To determine what evidence, if any, exists for, or against, the effectiveness of the atypical neuroleptics for analgesia...
  23. ncbi Do opioids induce hyperalgesia in humans? An evidence-based structured review
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at the University of Miami, Florida 33136, USA
    Pain Med 10:829-39. 2009
    ..This is a structured evidence-based review for all levels of evidence (all studies and case reports) on OIH in humans in order to determine the consistency of this evidence...
  24. ncbi Is chronic pain associated with somatization/hypochondriasis? An evidence-based structured review
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Pain Pract 9:449-67. 2009
    ..This is an evidence-based structured review...
  25. ncbi Allegations of medical malpractice in chronic opioid analgesic therapy possibly related to collaborative/split treatment and the P-450 enzyme system: forensic case report
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Pain Med 11:1419-25. 2010
    ..CONCLUSIONS: Split treatment can increase the difficulties in performing COAT. Clinicians should routinely consider the effects of all utilized drugs on the ability of the P450 enzyme system to metabolize/clear opioids...
  26. ncbi What is the evidence for chronic pain being etiologically associated with the DSM-IV category of sleep disorder due to a general medical condition? A structured evidence-based review
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at the University of Miami, Florida 33136, USA
    Pain Med 11:158-79. 2010
    ....
  27. ncbi Are chronic low back pain patients who smoke at greater risk for suicide ideation?
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA
    Pain Med 10:340-6. 2009
    ..The goal of this study was to determine if smoking is associated with suicide ideation in chronic low back pain (CLBP) patients...
  28. ncbi Are psychoactive substance (opioid)-dependent chronic pain patients hyperalgesic?
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at University of Miami, Miami, Florida, USA
    Pain Pract 11:337-43. 2011
    ..There are a number of such studies in opioid maintained addicts, but no such studies in chronic pain patients (CPPs) with current opioid addiction. The objective of this study was to determine if this group demonstrates hyperalgesia...
  29. ncbi Exploration of the illness uncertainty concept in acute and chronic pain patients vs community patients
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at University of Miami, Florida, USA
    Pain Med 11:658-69. 2010
    ..The secondary objectives were to determine if the LIDSI items are associated with the CRHCS items and to develop predictor models for the LIDSI items in APPs and CPPs...
  30. ncbi Is the location of nondermatomal sensory abnormalities (NDSAs) related to pain location?
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, Miami, Florida, USA
    Pain Med 4:238-43. 2003
    ..quot; The presence of NDSAs has historically been classified as a conversion symptom. We wished to determine if, in chronic pain patients (CPPs), NDSA location was associated with pain location...
  31. ncbi Multidisciplinary pain facility treatment outcome for pain-associated fatigue
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, Miami, FL 33136, USA
    Pain Med 6:299-304. 2005
    ..The purpose of this study was to determine whether chronic LBP- and chronic neck pain-associated fatigue responded to multidisciplinary multimodal treatment not specifically targeted to the treatment of fatigue...
  32. ncbi Genetic testing for enzymes of drug metabolism: does it have clinical utility for pain medicine at the present time? A structured review
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, Miami, Florida, USA
    Pain Med 5:81-93. 2004
    ..This is a structured review of genomic (genetic) testing for enzymes of drug metabolism...
  33. ncbi Is pain fatiguing? A structured evidence-based review
    David A Fishbain
    University of Miami, School of Medicine, Miami Beach, Florida, USA
    Pain Med 4:51-62. 2003
    ..This is a structured, evidence-based review of all available studies on the coexistence of fatigue and pain...
  34. ncbi Can the neuropathic pain scale discriminate between non-neuropathic and neuropathic pain?
    David A Fishbain
    Department of Psychiatry, University of Miami, Miami, Florida, USA
    Pain Med 9:149-60. 2008
    ....
  35. ncbi The prevalence of smokers within chronic pain patients and highest pain levels versus comparison groups
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at University of Miami, Miami, FL 33136, USA
    Pain Med 14:403-16. 2013
    ..CONCLUSIONS.: The prevalence of smokers could be significantly greater within CPPs vs CPWP. CPPs who smoke do not have higher levels of pain than nonsmoking CPPs...
  36. ncbi Do the proposed cervicogenic headache diagnostic criteria demonstrate specificity in terms of separating cervicogenic headache from migraine?
    David A Fishbain
    University of Miami, Comprehensive Pain and Rehabilitation Center, 600 Alton Road, Miami Beach, FL 33139, USA
    Curr Pain Headache Rep 7:387-94. 2003
    ..A significant model could not be built that did not include MH symptoms. As such, it has been concluded that it is unlikely that the criteria for CH will have the specificity required to separate CH patients from MH patients...
  37. ncbi Correlates of self-reported violent ideation against physicians in acute--and chronic-pain patients
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at University of Miami, FL 33136, USA
    Pain Med 10:573-85. 2009
    ..This study attempts to identify predictors for violent ideation against medical doctors (VI-MD), in acute-pain patients (APPs) and chronic-pain patients (CPPs). This is the first such study in the literature...
  38. ncbi What patient attributes are associated with thoughts of suing a physician?
    David A Fishbain
    Rosomoff Comprehensive Pain and Rehabilitation Center, University of Miami School of Medicine, Miami, FL, USA
    Arch Phys Med Rehabil 88:589-96. 2007
    ..To address a neglected research area: the attributes of rehabilitation patients associated with "thoughts of suing a physician" (S-MD)...
  39. ncbi Duloxetine status
    David A Fishbain
    Miller School of Medicine at the University of Miami, Miami, Florida, USA
    Pain Med 8:S25-6. 2007
  40. ncbi Polypharmacy treatment approaches to the psychiatric and somatic comorbidities found in patients with chronic pain
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine and Rosomoff Pain Center, Miami Beach, Florida, USA
    Am J Phys Med Rehabil 84:S56-63. 2005
    ....
  41. ncbi The relationship between antidepressant and analgesic responses: findings from six placebo-controlled trials assessing the efficacy of duloxetine in patients with major depressive disorder
    David A Fishbain
    University of Miami School of Medicine, Miami, FL, USA
    Curr Med Res Opin 24:3105-15. 2008
    ..This post-hoc analysis of six placebo-controlled duloxetine trials in patients with major depressive disorder was designed to compare onset of antidepressant activity to pain relief...
  42. ncbi Can patients taking opioids drive safely? A structured evidence-based review
    David A Fishbain
    University of Miami School of Medicine, University of Miami Comprehensive Pain and Rehabilitation Center, Miami Beach, FL 33139, USA
    J Pain Palliat Care Pharmacother 16:9-28. 2002
    ..As in all clinical decisions, this determination should be individualized according to clinical factors...
  43. ncbi Modafinil for the treatment of pain-associated fatigue: review and case report
    David A Fishbain
    Rosomoff Comprehensive Pain and Rehabilitation Center, 600 Alton Road, Miami Beach, FL 33139, USA
    J Pain Palliat Care Pharmacother 18:39-47. 2004
    ..There was dramatic improvement in fatigue and associated function. This case is described. It is the first such case report in the literature. The significance of this finding to the treatment of pain-associated fatigue is discussed...
  44. ncbi Is smoking associated with alcohol-drug dependence in patients with pain and chronic pain patients? An evidence-based structured review
    David A Fishbain
    Department of Psychiatry, Miller School of Medicine at the University of Miami, FL, USA
    Pain Med 13:1212-26. 2012
    ..The objective of this study was to determine if there is consistent evidence for smoking to be considered a red flag for development of opioid dependence during opioid exposure in patients with pain and chronic pain patients (CPPs)...
  45. ncbi Evidence-based treatment paradigms for depressed patients with pain and physical symptoms
    David A Fishbain
    Departments of Psychiatry and Behavioral Sciences, Neurological Surgery, and Anesthesiology, University of Miami Miller School of Medicine, Miami, Fla, USA
    J Clin Psychiatry 70:e22. 2009
    ..These dual-action agents have more consistently shown efficacy for pain than single-action agents...
  46. ncbi Relationships between functional capacity measures and baseline psychological measures in chronic pain patients
    Robert B Cutler
    Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Comprehensive Pain and Rehabilitation Center, South Shore Hospital, Miami, Florida, USA
    J Occup Rehabil 13:249-58. 2003
    ..Functional capacity measures are important predictors of follow-up employment outcome, but return to work cannot be predicted without taking pain into account...
  47. ncbi Medico-legal rounds: medico-legal issues and alleged breaches of "standards of medical care" in opioid rotation to methadone: a case report
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, Florida, USA
    Pain Med 4:195-201. 2003
    ....
  48. ncbi Are alcoholism treatments effective? The Project MATCH data
    Robert B Cutler
    Department of Psychiatry and Behavioral Sciences, University of Miami School of Medicine, Miami, Florida, USA
    BMC Public Health 5:75. 2005
    ..These results were interpreted post hoc as evidence that all three treatments were quite effective. We re-analyzed the data in order to estimate effectiveness in relation to quantity of treatment...
  49. ncbi Are opioid-dependent/tolerant patients impaired in driving-related skills? A structured evidence-based review
    David A Fishbain
    Department of Psychiatry, University of Miami School of Medicine, and University of Miami Comprehensive Pain and Rehabilitation Center at South Shore Hospital, Miami, Florida, USA
    J Pain Symptom Manage 25:559-77. 2003
    ..As such, additional controlled studies are required. Until more data are available, however, physicians may wish to consider the approach to this problem recommended in this review...
  50. ncbi Remission as the "gold standard" of treatment for depression with and without physical symptoms
    David A Fishbain
    Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USA
    J Clin Psychiatry 70:e07. 2009
    ..Understanding the synergic relationship between painful physical symptoms and depression is the first step in comprehensively treating patients with these conditions and helping them to achieve remission from depression...
  51. ncbi Chronic nonmalignant pain
    David A Fishbain
    J Rheumatol 29:2243; author reply 2243-4. 2002
  52. ncbi Influence of work related psychosocial factors and psychological distress on regional musculoskeletal pain
    David A Fishbain
    J Rheumatol 29:2246-7. 2002
  53. ncbi Analgesic effects of antidepressants
    David A Fishbain
    J Clin Psychiatry 64:96; author reply 96-7. 2003
  54. ncbi Diabetic peripheral neuropathic pain: clinical and quality-of-life issues
    Charles E Argoff
    New York University School of Medicine and Cohn Pain Management Center, Northshore University Hospital, Manhasset, USA
    Mayo Clin Proc 81:S3-11. 2006
    ..This article reviews the current knowledge about and presents recommendations for diagnostic assessment of DPN pain based on a review of the literature...
  55. ncbi Pain level as a predictor of return to work
    David A Fishbain
    Eur Spine J 12:451. 2003
  56. ncbi Comments on "prescription drug dependence and evolving beliefs about chronic pain management"
    David A Fishbain
    Am J Psychiatry 163:2194; author reply 2194-5. 2006
  57. ncbi Consensus guidelines: treatment planning and options. Diabetic peripheral neuropathic pain
    Charles E Argoff
    New York University School of Medicine and Cohn Pain Management Center, North Shore University Hospital, Manhasset, NY, USA
    Mayo Clin Proc 81:S12-25. 2006
    ..Ultimately, treatment choice must also Include consideration of adverse effects, individual patient factors such as comorbidities, and often cost...
  58. ncbi The pain-depression relationship
    David A Fishbain
    Psychosomatics 43:341; author reply 341-2. 2002
  59. ncbi Re: Secondary loss and pain-associated disability: theoretical overview and treatment implications
    David A Fishbain
    J Occup Rehabil 13:197-8; author reply 199. 2003
  60. ncbi Hysterical paralysis: a report of three cases and a review of the literature
    David A Fishbain
    Spine 28:1906. 2003
  61. ncbi Neck and upper limb pain
    David A Fishbain
    J Rheumatol 30:1124. 2003
  62. ncbi Integrated treatment approaches
    David A Fishbain
    Am J Psychiatry 159:2116-7; author reply 2117. 2002
  63. ncbi Concurrent validity of an electronic descriptive pain scale
    Roger A Scudds
    Department of Physical Therapy, Wichita State University, Kansas, USA
    Clin Rehabil 17:206-8. 2003
    ..The results showed relatively high significant correlations between the EDPS and each of the other pain scales...
  64. ncbi Predictive factors for suicidal ideation in patients with unresectable lung carcinoma. A 6-month follow-up study
    David A Fishbain
    Cancer 97:3127-8; author reply 3129. 2003
  65. ncbi Painful physical symptoms in depression: a clinical challenge
    Thomas N Wise
    The Department of Psychiatry and Behavioral Science, The George Washington University School of Medicine, Washington, DC, USA
    Pain Med 8:S75-82. 2007
    ..This mini review addresses the problems inherent to the treatment of painful physical symptoms in depression...