A H Fischer

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi request reprint The ultrastructure of MCF-10A acini
    Jean M Underwood
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Cell Physiol 208:141-8. 2006
  2. doi request reprint Performance differences between conventional smears and liquid-based preparations of thyroid fine-needle aspiration samples: analysis of 47,076 responses in the College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic Cytolog
    Andrew H Fischer
    Department of Cytopathology, University of Massachusetts, Worcester, MA 01605, USA
    Arch Pathol Lab Med 137:26-31. 2013
  3. ncbi request reprint Incorporating pathologists' criteria of malignancy into the evolutionary model for cancer development
    Andrew H Fischer
    Department of Pathology, H2 466 University Hospital, UMass Memorial Healthcare, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA
    J Cell Biochem 93:28-36. 2004
  4. ncbi request reprint Molecular aspects of diagnostic nucleolar and nuclear envelope changes in prostate cancer
    Andrew H Fischer
    Department of Pathology, University of Massachusetts UMMHC, Worcester, Massachusetts 01655, USA
    J Cell Biochem 91:170-84. 2004
  5. pmc Nuclear envelope irregularity is induced by RET/PTC during interphase
    Andrew H Fischer
    Department of Pathology, Emory University Hospital, Atlanta, Georgia, USA
    Am J Pathol 163:1091-100. 2003
  6. ncbi request reprint Method for procuring specific populations of viable human prostate cells for research
    A H Fischer
    Department of Pathology, Emory University, Atlanta, Georgia, USA
    Lab Invest 81:501-7. 2001
  7. pmc Papillary thyroid carcinoma oncogene (RET/PTC) alters the nuclear envelope and chromatin structure
    A H Fischer
    Department of Pathology, Emory University Hospital, Atlanta, Georgia 30322, USA
    Am J Pathol 153:1443-50. 1998
  8. ncbi request reprint Ras-associated nuclear structural change appears functionally significant and independent of the mitotic signaling pathway
    A H Fischer
    Department of Pathology, Emory University Hospital, Atlanta, Georgia 30322, USA
    J Cell Biochem 70:130-40. 1998
  9. ncbi request reprint Nuclear envelope organization in papillary thyroid carcinoma
    A H Fischer
    Department of Pathology, Emory University Hospital, Atlanta, USA
    Histol Histopathol 16:1-14. 2001
  10. pmc The evolution of tumor biology: seeking a balance between gene expression profiling and morphology studies
    Andrew H Fischer
    J Mol Diagn 4:65. 2002

Collaborators

Detail Information

Publications13

  1. ncbi request reprint The ultrastructure of MCF-10A acini
    Jean M Underwood
    Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Cell Physiol 208:141-8. 2006
    ..Electron microscopy has the resolution required to survey features of MCF-10A cell and acinus architecture that may change with manipulations designed to induce malignant phenotypes...
  2. doi request reprint Performance differences between conventional smears and liquid-based preparations of thyroid fine-needle aspiration samples: analysis of 47,076 responses in the College of American Pathologists Interlaboratory Comparison Program in Non-Gynecologic Cytolog
    Andrew H Fischer
    Department of Cytopathology, University of Massachusetts, Worcester, MA 01605, USA
    Arch Pathol Lab Med 137:26-31. 2013
    ..Controversy exists about whether thyroid fine-needle aspirates (FNAs) should be processed with conventional smears or liquid-based preparations (LBPs)...
  3. ncbi request reprint Incorporating pathologists' criteria of malignancy into the evolutionary model for cancer development
    Andrew H Fischer
    Department of Pathology, H2 466 University Hospital, UMass Memorial Healthcare, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA
    J Cell Biochem 93:28-36. 2004
    ..Finally, a full evolutionary framework incorporating the criteria of malignancy restores congruity between the histogenetic classification and the emerging molecular classification of cancer...
  4. ncbi request reprint Molecular aspects of diagnostic nucleolar and nuclear envelope changes in prostate cancer
    Andrew H Fischer
    Department of Pathology, University of Massachusetts UMMHC, Worcester, Massachusetts 01655, USA
    J Cell Biochem 91:170-84. 2004
    ..NE irregularity could also promote chromosomal instability because it leads to chromosomal asymmetry in metaphase. Finally, NE irregularity could impact replication competence, transcriptional programming and nuclear pore function...
  5. pmc Nuclear envelope irregularity is induced by RET/PTC during interphase
    Andrew H Fischer
    Department of Pathology, Emory University Hospital, Atlanta, Georgia, USA
    Am J Pathol 163:1091-100. 2003
    ..Since irregularity develops quickly, and since no mitoses and only rare possible postmitotic cells were scored, postmitotic NE re-assembly does not appear necessary for RET/PTC signaling to induce an irregular NE contour...
  6. ncbi request reprint Method for procuring specific populations of viable human prostate cells for research
    A H Fischer
    Department of Pathology, Emory University, Atlanta, Georgia, USA
    Lab Invest 81:501-7. 2001
    ..The procedure takes only about 30 minutes...
  7. pmc Papillary thyroid carcinoma oncogene (RET/PTC) alters the nuclear envelope and chromatin structure
    A H Fischer
    Department of Pathology, Emory University Hospital, Atlanta, Georgia 30322, USA
    Am J Pathol 153:1443-50. 1998
    ..A signaling pathway downstream of RET/ PTC leads to restructuring of the nuclear envelope and chromatin, and the signal does not depend entirely, if at all, on a RAS pathway...
  8. ncbi request reprint Ras-associated nuclear structural change appears functionally significant and independent of the mitotic signaling pathway
    A H Fischer
    Department of Pathology, Emory University Hospital, Atlanta, Georgia 30322, USA
    J Cell Biochem 70:130-40. 1998
    ..Based on published studies of five of the cell lines, there may be a correlation between increases in certain nuclear matrix proteins and the Ras-associated nuclear change...
  9. ncbi request reprint Nuclear envelope organization in papillary thyroid carcinoma
    A H Fischer
    Department of Pathology, Emory University Hospital, Atlanta, USA
    Histol Histopathol 16:1-14. 2001
    ..We review the structure of the nuclear envelope, the major factors that determine nuclear shape, and the possible functional consequences of its alteration in PTC...
  10. pmc The evolution of tumor biology: seeking a balance between gene expression profiling and morphology studies
    Andrew H Fischer
    J Mol Diagn 4:65. 2002
  11. ncbi request reprint Application of the Cre/loxP system to enhance thyroid-targeted expression of sodium/iodide symporter
    Xiaoqin Lin
    Department of Physiology and Cell Biology, Ohio State University, Columbus, Ohio 43210, USA
    J Clin Endocrinol Metab 89:2344-50. 2004
    ..Finally, Tg promoter activity was partially restored in malignant thyroid cells by forced expression of the paired domain-containing transcription factor (Pax-8), allowing the Cre/loxP system to mildly enhance radioiodide uptake...
  12. ncbi request reprint Nuclear structure in cancer cells
    Daniele Zink
    University of Munich LMU, Department of Biology II, Goethestr 31, 80336 Munich, Germany
    Nat Rev Cancer 4:677-87. 2004
    ..Advances in understanding nuclear structure have revealed insights into the process of malignant transformation and provide a basis for the development of new diagnostic tools and therapeutics...
  13. ncbi request reprint Inducible changes in cell size and attachment area due to expression of a mutant SWI/SNF chromatin remodeling enzyme
    David A Hill
    Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    J Cell Sci 117:5847-54. 2004
    ..These findings demonstrate that gene expression pathways affected by chromatin remodeling enzymes can regulate the physical dimensions of mammalian cell morphology...