Matthew A Firpo

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. ncbi request reprint The clinical utility of CA 19-9 in pancreatic adenocarcinoma: diagnostic and prognostic updates
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Curr Mol Med 13:340-51. 2013
  2. pmc A conscious mouse model of gastric ileus using clinically relevant endpoints
    Matthew A Firpo
    Department of Surgery, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132, USA
    BMC Gastroenterol 5:18. 2005
  3. pmc Improved diagnosis of pancreatic adenocarcinoma using haptoglobin and serum amyloid A in a panel screen
    Matthew A Firpo
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    World J Surg 33:716-22. 2009
  4. pmc Serum osteopontin and tissue inhibitor of metalloproteinase 1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pancreas 42:193-7. 2013
  5. ncbi request reprint Natural history of pancreatic cancer recurrence following "curative" resection in athymic mice
    Marcus J Torgenson
    Department of Surgery, University of Utah, Salt Lake City, Utah 84132, USA
    J Surg Res 149:57-61. 2008
  6. ncbi request reprint Anti-inflammatory effects of PPAR-gamma agonists directly correlate with PPAR-gamma expression during acute pancreatitis
    Michael D Rollins
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    J Gastrointest Surg 10:1120-30. 2006
  7. pmc Serum platelet factor 4 is an independent predictor of survival and venous thromboembolism in patients with pancreatic adenocarcinoma
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Cancer Epidemiol Biomarkers Prev 19:2605-10. 2010
  8. ncbi request reprint Synthetic extracellular matrix enhances tumor growth and metastasis in an orthotopic mouse model of pancreatic adenocarcinoma
    Courtney L Scaife
    Department of Surgery, University of Utah, 30 North 1900 East, Salt Lake City, UT 84132, USA
    J Gastrointest Surg 12:1074-80. 2008
  9. pmc Phenotype and genotype of pancreatic cancer cell lines
    Emily L Deer
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pancreas 39:425-35. 2010
  10. ncbi request reprint Serum IGFBP2 and MSLN as diagnostic and prognostic biomarkers for pancreatic cancer
    Zachary W Kendrick
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA
    HPB (Oxford) 16:670-6. 2014

Collaborators

Detail Information

Publications21

  1. ncbi request reprint The clinical utility of CA 19-9 in pancreatic adenocarcinoma: diagnostic and prognostic updates
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Curr Mol Med 13:340-51. 2013
    ..We also present a summary of the use of CA 19-9 as a prognostic tool and evaluate CA 19-9 diagnostic and prognostic utility in a 10-year, single institution experience...
  2. pmc A conscious mouse model of gastric ileus using clinically relevant endpoints
    Matthew A Firpo
    Department of Surgery, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT 84132, USA
    BMC Gastroenterol 5:18. 2005
    ....
  3. pmc Improved diagnosis of pancreatic adenocarcinoma using haptoglobin and serum amyloid A in a panel screen
    Matthew A Firpo
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    World J Surg 33:716-22. 2009
    ....
  4. pmc Serum osteopontin and tissue inhibitor of metalloproteinase 1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pancreas 42:193-7. 2013
    ..We assessed serum osteopontin (OPN) and tissue inhibitor of metalloproteinase 1 (TIMP-1) as possible diagnostic and prognostic biomarkers in a novel cohort of patients with pancreatic cancer...
  5. ncbi request reprint Natural history of pancreatic cancer recurrence following "curative" resection in athymic mice
    Marcus J Torgenson
    Department of Surgery, University of Utah, Salt Lake City, Utah 84132, USA
    J Surg Res 149:57-61. 2008
    ..Following "curative" pancreatic resection, we demonstrate postoperative disease recurrence by fluorescence imaging...
  6. ncbi request reprint Anti-inflammatory effects of PPAR-gamma agonists directly correlate with PPAR-gamma expression during acute pancreatitis
    Michael D Rollins
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA
    J Gastrointest Surg 10:1120-30. 2006
    ..Our data are the first to demonstrate that PPAR-gamma agonists represent a promising therapeutic strategy for acute pancreatitis...
  7. pmc Serum platelet factor 4 is an independent predictor of survival and venous thromboembolism in patients with pancreatic adenocarcinoma
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, Utah, USA
    Cancer Epidemiol Biomarkers Prev 19:2605-10. 2010
    ..Platelet factor 4 (PF4) has been proposed as a diagnostic biomarker for PDAC. We assessed the diagnostic and prognostic potential of serum PF4 levels in PDAC patients...
  8. ncbi request reprint Synthetic extracellular matrix enhances tumor growth and metastasis in an orthotopic mouse model of pancreatic adenocarcinoma
    Courtney L Scaife
    Department of Surgery, University of Utah, 30 North 1900 East, Salt Lake City, UT 84132, USA
    J Gastrointest Surg 12:1074-80. 2008
    ..The advantages of this new approach can be utilized to investigate the mechanisms of tumor progression and test novel therapeutic agents in vivo...
  9. pmc Phenotype and genotype of pancreatic cancer cell lines
    Emily L Deer
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    Pancreas 39:425-35. 2010
    ..Identification of both consensus and discrepant information in the literature suggests careful evaluation before selection of cell lines and attention be given to cell line authentication...
  10. ncbi request reprint Serum IGFBP2 and MSLN as diagnostic and prognostic biomarkers for pancreatic cancer
    Zachary W Kendrick
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA
    HPB (Oxford) 16:670-6. 2014
    ..Insulin-like growth factor binding protein 2 (IGFBP2) and mesothelin (MSLN) have shown potential as serum biomarkers in other cancers, but have not been adequately studied in PDAC...
  11. ncbi request reprint Screening for pancreatic cancer: why, how, and who?
    Katherine E Poruk
    Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, USA
    Ann Surg 257:17-26. 2013
    ..At this time, given the lack of proven benefit in this disease, screening efforts should probably be undertaken in the context of prospective trials...
  12. pmc Sustained activation of nuclear erythroid 2-related factor 2/antioxidant response element signaling promotes reductive stress in the human mutant protein aggregation cardiomyopathy in mice
    Namakkal Soorappan Rajasekaran
    Division of Cardiology, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA
    Antioxid Redox Signal 14:957-71. 2011
    ..Our findings implicate a novel pathway for therapeutic targeting and abrogating RS linked to experimental cardiomyopathy in humans. Antioxid...
  13. pmc Toward development of a surface-enhanced Raman scattering (SERS)-based cancer diagnostic immunoassay panel
    Jennifer H Granger
    Department of Chemistry, University of Utah, Salt Lake City, UT 84112, USA
    Analyst 138:410-6. 2013
    ..We describe the design and development of a proof-of-concept PA biomarker immunoassay array coupled with surface-enhanced Raman scattering (SERS) as a sensitive readout method...
  14. pmc Prognostic significance of PINCH signalling in human pancreatic ductal adenocarcinoma
    Courtney L Scaife
    Department of Surgery, University of Utah, Salt Lake City, UT 84132, USA
    HPB (Oxford) 12:352-8. 2010
    ..Recently, interest has developed in the accuracy of integrin-associated PINCH protein expression in human cancers as a predictive marker of tumour status. The goal of this study was to define the expression of PINCH protein in PDA...
  15. ncbi request reprint Trends in research support and productivity in the changing environment of academic surgery
    Heidi H Jackson
    Department of Surgery, University of Utah, Salt Lake City, Utah 84132, USA
    J Surg Res 116:197-201. 2004
    ..We hypothesized that the changing environment of academic surgery has resulted in a decrease in surgical research funding and basic surgical research productivity of academic departments of surgery...
  16. doi request reprint Comparative analysis of detection methods for congenital cytomegalovirus infection in a Guinea pig model
    Albert H Park
    Divisions of Otolaryngology Head and Neck Surgery, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    JAMA Otolaryngol Head Neck Surg 139:82-6. 2013
    ..To assess the validity of the guinea pig as a model for congenital cytomegalovirus (CMV) infection by comparing the effectiveness of detecting the virus by real-time polymerase chain reaction (PCR) in blood, urine, and saliva...
  17. pmc Impaired transcriptional activity of Nrf2 in age-related myocardial oxidative stress is reversible by moderate exercise training
    Sellamuthu S Gounder
    Divisions of Cardiology and Pulmonary, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, USA
    PLoS ONE 7:e45697. 2012
    ..These observations suggest that enhancing Nrf2 function and endogenous cytoprotective mechanisms by MET, may combat age-induced ROS/RNS and protect the myocardium from oxidative stress diseases...
  18. pmc β-catenin is selectively required for the expansion and regeneration of mature pancreatic acinar cells in mice
    Matthew D Keefe
    Department of Human Genetics, University of Utah School of Medicine, Salt Lake City, UT 84112, USA
    Dis Model Mech 5:503-14. 2012
    ....
  19. ncbi request reprint Effect of gelatin on heparin regulation of cytokine release from hyaluronan-based hydrogels
    Robert A Peattie
    Department of Biomedical Engineering, Tufts University, Medford, Massachusetts 02155, USA
    Drug Deliv 15:389-97. 2008
    ..8% for PDGF, a 45-fold difference. Furthermore, gels containing either VEGF of Ang-1 produced twice the vascularization response in vivo as gels not containing a growth factor. Thus, those GFs maintained strong physiologic effectiveness...
  20. pmc Microvascular maturity elicited in tissue treated with cytokine-loaded hyaluronan-based hydrogels
    Luke W Hosack
    Department of Chemical Engineering, Oregon State University, 102 Gleeson Hall, Corvallis, OR 97331 2702, United States
    Biomaterials 29:2336-47. 2008
    ....
  21. ncbi request reprint Heparin-regulated release of growth factors in vitro and angiogenic response in vivo to implanted hyaluronan hydrogels containing VEGF and bFGF
    Daniel B Pike
    Department of Chemical Engineering, Oregon State University, 102 Gleeson Hall, Corvallis, OR 97331, USA
    Biomaterials 27:5242-51. 2006
    ..The ability to stimulate localized microvessel growth at controlled rates for extended times through the release of GFs from covalently linked, Hp-supplemented hydrogels will ultimately provide a powerful therapeutic tool...