Roger B Fillingim

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans
    Roger B Fillingim
    University of Florida College of Dentistry, Gainesville, FL 32610, USA
    J Pain 6:159-67. 2005
  2. ncbi Cluster analysis of multiple experimental pain modalities
    Barbara A Hastie
    University of Florida College of Dentistry, Division of Public Health Services and Research, 1600 SW Archer Road, HSC D8 37, P O Box 100404, Gainesville, FL 32610 0404, USA
    Pain 116:227-37. 2005
  3. pmc Biopsychosocial influence on exercise-induced delayed onset muscle soreness at the shoulder: pain catastrophizing and catechol-o-methyltransferase (COMT) diplotype predict pain ratings
    Steven Z George
    Department of Physical Therapy, Brooks Center for Rehabilitation Studies, University of Florida, Gainesville, FL 32610 0154, USA
    Clin J Pain 24:793-801. 2008
  4. doi Cognitive-affective and somatic side effects of morphine and pentazocine: side-effect profiles in healthy adults
    Joseph L Riley
    Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL 32610 3628, USA
    Pain Med 11:195-206. 2010
  5. pmc Ethnicity interacts with the OPRM1 gene in experimental pain sensitivity
    Barbara A Hastie
    Department of Community Dentistry and Behavioral Science, University of Florida College of Dentistry, Gainesville, FL 32610 3628, USA
    Pain 153:1610-9. 2012
  6. ncbi Morphine responses and experimental pain: sex differences in side effects and cardiovascular responses but not analgesia
    Roger B Fillingim
    Public Health Services and Research, University of Florida College of Dentistry, 1600 SW Archer Road, Gainesville, FL 32610 0404, USA
    J Pain 6:116-24. 2005
  7. pmc Is the pain-reducing effect of opioid medication reliable? A psychophysical study of morphine and pentazocine analgesia
    Christopher D King
    Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL, USA
    Pain 154:476-83. 2013
  8. pmc Affect balance style, experimental pain sensitivity, and pain-related responses
    Kimberly T Sibille
    Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL 32610, USA
    Clin J Pain 28:410-7. 2012
  9. ncbi Do men and women differ on measures of mental stress-induced ischemia?
    Kaki M York
    Cardiovascular Research, Department of Medicine, University of Florida, Gainesville, Florida, USA
    Psychosom Med 69:918-22. 2007
  10. pmc Individual differences in morphine and butorphanol analgesia: a laboratory pain study
    Kimberly T Sibille
    Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL 32610 3629, USA
    Pain Med 12:1076-85. 2011

Detail Information

Publications89

  1. ncbi The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans
    Roger B Fillingim
    University of Florida College of Dentistry, Gainesville, FL 32610, USA
    J Pain 6:159-67. 2005
    ..The results indicate that the rare allele is associated with higher pressure pain thresholds. These results support previous contentions that OPRM1 may be a pain-relevant gene; however, replication of these findings is needed...
  2. ncbi Cluster analysis of multiple experimental pain modalities
    Barbara A Hastie
    University of Florida College of Dentistry, Division of Public Health Services and Research, 1600 SW Archer Road, HSC D8 37, P O Box 100404, Gainesville, FL 32610 0404, USA
    Pain 116:227-37. 2005
    ..These findings highlight the need for future investigation to identify patterns of responses across different pain modalities in order to more accurately characterize individual differences in responses to experimental pain...
  3. pmc Biopsychosocial influence on exercise-induced delayed onset muscle soreness at the shoulder: pain catastrophizing and catechol-o-methyltransferase (COMT) diplotype predict pain ratings
    Steven Z George
    Department of Physical Therapy, Brooks Center for Rehabilitation Studies, University of Florida, Gainesville, FL 32610 0154, USA
    Clin J Pain 24:793-801. 2008
    ..This study investigated whether these same psychologic and genetic factors predicted responses to induced shoulder pain...
  4. doi Cognitive-affective and somatic side effects of morphine and pentazocine: side-effect profiles in healthy adults
    Joseph L Riley
    Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL 32610 3628, USA
    Pain Med 11:195-206. 2010
    ....
  5. pmc Ethnicity interacts with the OPRM1 gene in experimental pain sensitivity
    Barbara A Hastie
    Department of Community Dentistry and Behavioral Science, University of Florida College of Dentistry, Gainesville, FL 32610 3628, USA
    Pain 153:1610-9. 2012
    ..These findings demonstrate an ethnicity-dependent association of OPRM1 genotype with pain sensitivity. Additional research is warranted to uncover the mechanisms influencing these relationships...
  6. ncbi Morphine responses and experimental pain: sex differences in side effects and cardiovascular responses but not analgesia
    Roger B Fillingim
    Public Health Services and Research, University of Florida College of Dentistry, 1600 SW Archer Road, Gainesville, FL 32610 0404, USA
    J Pain 6:116-24. 2005
    ..These results suggest that sex differences in responses to morphine might depend on the pain model and/or drug dose as well as the specific end point assessed...
  7. pmc Is the pain-reducing effect of opioid medication reliable? A psychophysical study of morphine and pentazocine analgesia
    Christopher D King
    Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, FL, USA
    Pain 154:476-83. 2013
    ..These results suggest that analgesic measures are able to distinguish between active drugs. In addition, analgesic responses to morphine and pentazocine demonstrate at least moderate reliability...
  8. pmc Affect balance style, experimental pain sensitivity, and pain-related responses
    Kimberly T Sibille
    Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL 32610, USA
    Clin J Pain 28:410-7. 2012
    ..Psychological factors and experimental pain sensitivity are indicated as predictors of chronic pain onset. The current study investigated the relationship between ABS, pain sensitivity, and pain-related measures in healthy adults...
  9. ncbi Do men and women differ on measures of mental stress-induced ischemia?
    Kaki M York
    Cardiovascular Research, Department of Medicine, University of Florida, Gainesville, Florida, USA
    Psychosom Med 69:918-22. 2007
    ..However, little is known about the effects of mental stress on ischemic processes in women. Most studies to date either had few women or required a positive exercise stress test...
  10. pmc Individual differences in morphine and butorphanol analgesia: a laboratory pain study
    Kimberly T Sibille
    Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, Gainesville, FL 32610 3629, USA
    Pain Med 12:1076-85. 2011
    ..This laboratory study was designed to examine the contributions of sex and race to inter-individual variability in response to opioids...
  11. ncbi Sex-related psychological predictors of baseline pain perception and analgesic responses to pentazocine
    Roger B Fillingim
    University of Florida College of Dentistry, Public Health Services and Research, 1600 SW Archer Road, Room D8 44A, P O Box 100404, Gainesville, FL 32610 0404, USA
    Biol Psychol 69:97-112. 2005
    ..These findings indicate sex-dependent associations of psychological factors with baseline pain perception, analgesic responses, and medication side effects...
  12. doi Usefulness of peripheral arterial tonometry in the detection of mental stress-induced myocardial ischemia
    Mustafa Hassan
    Division of Cardiology, Department of Medicine, University of Florida, Gainesville, Florida, USA
    Clin Cardiol 32:E1-6. 2009
    ..Peripheral arterial vasoconstriction has been consistently reported as an underlying mechanism for ischemia development in this setting and as such affords a unique opportunity for the noninvasive detection of this phenomenon...
  13. pmc Investigation of central pain processing in shoulder pain: converging results from 2 musculoskeletal pain models
    Carolina Valencia
    Department of Physical Therapy, University of Florida, Gainesville, Florida 32611 0154, USA
    J Pain 13:81-9. 2012
    ..Collectively our findings support neuroplastic changes in pain modulation were associated with decreases in clinical pain intensity only, and could be detected more readily with thermal stimuli...
  14. doi Comparison of graded exercise and graded exposure clinical outcomes for patients with chronic low back pain
    Steven Z George
    Center for Pain Research and Behavioral Health, Department of Physical Therapy, University of Florida, Gainesville, FL 32611 0154, USA
    J Orthop Sports Phys Ther 40:694-704. 2010
    ..Quasi-experimental clinical trial...
  15. ncbi Ethnic differences in responses to multiple experimental pain stimuli
    Claudia M Campbell
    College of Clinical and Health Psychology, University of Florida, Gainesville, FL 32610 0404, USA
    Pain 113:20-6. 2005
    ..Hypervigilance partly accounted for group differences. Additional research to determine the mechanisms underlying these effects is warranted...
  16. pmc Comparison of peripheral arterial response to mental stress in men versus women with coronary artery disease
    Mustafa Hassan
    Cardiovascular Research, Division of Cardiology, Department of Medicine, University of Florida, Gainesville, Florida, USA
    Am J Cardiol 102:970-4. 2008
    ..This finding may suggest that men have higher susceptibility to mental stress-related adverse effects. Additional studies are needed to determine the significance of this finding...
  17. pmc Drug response profiles to experimental pain are opioid and pain modality specific
    Lindsay L Kindler
    Comprehensive Center for Pain Research, University of Florida College of Dentistry, Gainesville, Florida, USA
    J Pain 12:340-51. 2011
    ....
  18. pmc A quantitative review of ethnic group differences in experimental pain response: do biology, psychology, and culture matter?
    Bridgett Rahim-Williams
    Department of Behavioral Science and Community Health, University of Florida, College of Public Health and Health Professions, Gainesville, Florida 32610, USA
    Pain Med 13:522-40. 2012
    ..Pain is a subjectively complex and universal experience. We examine research investigating ethnic group differences in experimental pain response and factors contributing to group differences...
  19. ncbi Sex and pain-related psychological variables are associated with thermal pain sensitivity for patients with chronic low back pain
    Steven Z George
    Department of Physical Therapy, Brooks Center for Rehabilitation Studies, University of Florida, Gainesville, FL 32611 0154, USA
    J Pain 8:2-10. 2007
    ....
  20. pmc Lack of endogenous modulation and reduced decay of prolonged heat pain in older adults
    Joseph L Riley
    Department of Behavioral Sciences, University of Florida, Gainesville, FL 32610 3628, USA
    Pain 150:153-60. 2010
    ..Since a number of neurotransmitter systems are involved in pain modulation, it is possible age-related differences in CPM are due to functional changes in these systems in a number of areas within the neuroaxis...
  21. doi Association of beta1-adrenergic receptor genetic polymorphism with mental stress-induced myocardial ischemia in patients with coronary artery disease
    Mustafa Hassan
    Cardiovascular Research, Division of Cardiology, Department of Medicine, College of Pharmacy, University of Florida, 1601 SW Archer Rd, Code 111 D, Gainesville, FL 32608, USA
    Arch Intern Med 168:763-70. 2008
    ....
  22. ncbi Experimental pain models reveal no sex differences in pentazocine analgesia in humans
    Roger B Fillingim
    University of Florida College of Dentistry, Public Health Services and Research, 1600 Southwest Archer Road, Room D8 44A, P O Box 100404, Gainesville, Florida 32610 0404, USA
    Anesthesiology 100:1263-70. 2004
    ..g., pentazocine, nalbuphine, butorphanol) among women than among men. However, evidence of sex differences in kappa-agonist-antagonist effects from studies of experimentally induced pain in humans is lacking...
  23. pmc Smoking status and pain level among head and neck cancer patients
    Henrietta L Logan
    Department of Community Dentistry and Behavioral Science, University of Florida, Gainesville, Florida 32610, USA
    J Pain 11:528-34. 2010
    ..and P's < .0001) even after controlling for stage of diagnosis. In addition, current smokers reported significantly greater interference from the pain (F(2,73) = 10.5 P < .0001)...
  24. pmc Suprathreshold heat pain response is associated with clinical pain intensity for patients with shoulder pain
    Carolina Valencia
    Department of Physical Therapy, University of Florida, Gainesville, FL 32611, USA
    J Pain 12:133-40. 2011
    ..These data suggest that assessment of pain should include suprathreshold heat stimuli and psychological factors separately, and a combination of these factors may be predictive of pain intensity outcomes...
  25. ncbi Fear-avoidance beliefs and temporal summation of evoked thermal pain influence self-report of disability in patients with chronic low back pain
    Steven Z George
    Department of Physical Therapy, Brooks Center for Rehabilitation Studies, University of Florida, Gainesville, Florida 32611 0154, USA
    J Occup Rehabil 16:95-108. 2006
    ....
  26. pmc Effects of genetic variation in H3K79 methylation regulatory genes on clinical blood pressure and blood pressure response to hydrochlorothiazide
    Julio D Duarte
    Center for Pharmacogenomics and Department of Pharmacotherapy and Translational Research, University of Florida, Gainesville, FL 32610, USA
    J Transl Med 10:56. 2012
    ..This study aimed to determine the role of variation in these regulatory genes on blood pressure response to HCTZ, and secondarily, untreated blood pressure...
  27. pmc Ethnic differences in the nociceptive flexion reflex (NFR)
    Claudia M Campbell
    University of Florida, Department of Clinical and Health Psychology, Gainesville, FL, USA
    Pain 134:91-6. 2008
    ..These results extend previous research on ethnic differences in self-report measures of pain by demonstrating group differences in a nociceptive muscle reflex...
  28. pmc Variability of myocardial ischemic responses to mental versus exercise or adenosine stress in patients with coronary artery disease
    Mustafa Hassan
    Division of Cardiology, Department of Medicine, University of Florida, Gainesville, FL, USA
    J Nucl Cardiol 15:518-25. 2008
    ..In this study we sought to compare the within-individual ischemic responses to mental versus exercise or adenosine stress in a cohort of CAD patients...
  29. ncbi Fear of pain influences outcomes after exercise-induced delayed onset muscle soreness at the shoulder
    Steven Z George
    Department of Physical Therapy, Brooks Center for Rehabilitation Studies, University of Florida, Gainesville, FL 32611 0154, USA
    Clin J Pain 23:76-84. 2007
    ..This study investigated whether anxiety, fear of pain, or pain catastrophizing were predictive of pain-related outcomes after induced delayed onset muscle soreness (DOMS) at the shoulder...
  30. ncbi Ethnic differences and responses to pain in healthy young adults
    Barbara A Hastie
    University of Florida College of Dentistry, Division of Public Health Services and Research, Gainesville, Florida 32610, USA
    Pain Med 6:61-71. 2005
    ..These findings may have important implications for understanding ethnic differences in responses to clinical pain and for tailoring treatment approaches to eliminate disparities...
  31. pmc The effect of acute psychological stress on QT dispersion in patients with coronary artery disease
    Mustafa Hassan
    Division of Cardiology, Department of Medicine, University of Florida, Gainesville, Florida, USA
    Pacing Clin Electrophysiol 32:1178-83. 2009
    ..Mental stress-induced myocardial ischemia occurs in a significant percentage of the CAD population. It is unknown if the proarrhythmic effects of psychological stress are mediated through the development of myocardial ischemia...
  32. pmc A meta-analytic review of the hypoalgesic effects of exercise
    Kelly M Naugle
    Pain Research and Intervention Center for Excellence, University of Florida, Gainesville, FL, USA
    J Pain 13:1139-50. 2012
    ..While trends could be identified, the optimal dose of exercise that is needed to produce hypoalgesia could not be systematically determined with the amount of data available...
  33. pmc Reduction of conditioned pain modulation in humans by naltrexone: an exploratory study of the effects of pain catastrophizing
    Christopher D King
    Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, 1329 SW 16th St, Gainesville, FL 32610 3628, USA
    J Behav Med 36:315-27. 2013
    ....
  34. pmc Chronic pain, perceived stress, and cellular aging: an exploratory study
    Kimberly T Sibille
    College of Dentistry, University of Florida, Gainesville, FL 32610 3628, USA
    Mol Pain 8:12. 2012
    ..However, the utility of TL as a biological marker reflecting the burden of chronic pain and psychosocial stress has not yet been explored...
  35. ncbi Is self-reported childhood abuse history associated with pain perception among healthy young women and men?
    Roger B Fillingim
    University of Florida College of Dentistry and Gainesville VA Medical Center, Gainesville, FL 32610 0404, USA
    Clin J Pain 21:387-97. 2005
    ..The purpose of this study was to examine the association between self-reported history of childhood sexual or physical abuse and experimental pain responses in a nonclinical sample of generally healthy young adults...
  36. pmc Evidence for a biopsychosocial influence on shoulder pain: pain catastrophizing and catechol-O-methyltransferase (COMT) diplotype predict clinical pain ratings
    Steven Z George
    Department of Physical Therapy, Brooks Center for Rehabilitation Studies, University of Florida, Gainesville, FL, USA
    Pain 136:53-61. 2008
    ..0/10 or higher. Our findings suggest that an interaction between pain catastrophizing and COMT diplotype has the potential to influence pain ratings in patients seeking operative treatment of their shoulder pain...
  37. ncbi Advanced continuous-contact heat pulse design for efficient temporal summation of second pain (windup)
    Roland Staud
    Department of Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA
    J Pain 7:575-82. 2006
    ..The results of this study will allow more efficient use of currently available constant-contact thermodes for clinical and research applications...
  38. ncbi Sex differences in the associations among psychological factors and pain report: a novel psychophysical study of patients with chronic low back pain
    Michael E Robinson
    Center for Pain Research and Behavioral Health, Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida 32610, USA
    J Pain 6:463-70. 2005
    ..00, P < .05) were significantly stronger in men than women. These findings suggest that anxiety was linked to self-reported and induced low back pain for men, but not for women...
  39. pmc Sex, gender, and pain: a review of recent clinical and experimental findings
    Roger B Fillingim
    University of Florida, College of Dentistry, Gainesville, Florida 32610 3628, USA
    J Pain 10:447-85. 2009
    ..The article concludes with a discussion of potential biopsychosocial mechanisms that may underlie sex differences in pain, and considerations for future research are discussed...
  40. pmc Deficiency in endogenous modulation of prolonged heat pain in patients with Irritable Bowel Syndrome and Temporomandibular Disorder
    Christopher D King
    Department of Community Dentistry and Behavioral Science, University of Florida College of Dentistry, 1329 SW 16th Street, Suite 5180, PO Box 103628, Gainesville, FL 32610 3628, USA
    Pain 143:172-8. 2009
    ..These findings support the idea that chronic pain patients are not only more pain sensitive but also demonstrate reduced pain inhibition by pain, possibly because of dysfunction of endogenous pain inhibition systems...
  41. pmc Subjective sleep quality and ethnicity are interactively related to standard and situation-specific measures of pain catastrophizing
    Burel R Goodin
    Comprehensive Center for Pain Research, University of Florida College of Dentistry, Gainesville, Florida 32610, USA
    Pain Med 12:913-22. 2011
    ..The current study examined the cross-sectional associations of subjective sleep quality, ethnicity, and their interaction with pain catastrophizing and pain reports...
  42. ncbi Individual differences in pain responses
    Roger B Fillingim
    University of Florida College of Dentistry, Public Health Services and Research, PO Box 100404, Gainesville, FL 32610 0404, USA
    Curr Rheumatol Rep 7:342-7. 2005
    ..Finally, the clinical and scientific implications of individual differences in pain are discussed...
  43. ncbi Sensory and affective pain discrimination after inhalation of essential oils
    Jeffrey J Gedney
    Division of Public Health Services and Research, University of Florida College of Dentistry, Gainesville, FL, USA
    Psychosom Med 66:599-606. 2004
    ..The purpose of this investigation was to examine the effects of olfactory absorption of two commonly used therapeutic essential oils on sensory and affective responses to experimentally induced pain...
  44. pmc A computational model for sex-specific genetic architecture of complex traits in humans: implications for mapping pain sensitivity
    Chenguang Wang
    Department of Statistics, University of Florida, Gainesville, FL 32611 USA
    Mol Pain 4:13. 2008
    ..The model could have important implications for mapping complex trait genes and studying the detailed genetic architecture of sex-specific differences...
  45. ncbi Clinical characteristics of chronic back pain as a function of gender and oral opioid use
    Roger B Fillingim
    University of Florida College of Dentistry and North Florida South Georgia VA Health System, Gainesville 32610, USA
    Spine (Phila Pa 1976) 28:143-50. 2003
    ..A cross-sectional analysis of data derived from patients with chronic spinal pain undergoing evaluation at a multidisciplinary pain treatment center was conducted...
  46. ncbi Multidimensional success criteria and expectations for treatment of chronic pain: the patient perspective
    Michael E Robinson
    Department of Clinical and Health Psychology, University of Florida, Florida 32610, USA
    Pain Med 6:336-45. 2005
    ..Secondary objectives include examination of patient expectations for treatment across domains and derivation of patient subgroups based on PCOQ responses...
  47. pmc Sex differences in experimental and clinical pain sensitivity for patients with shoulder pain
    Lindsay L Kindler
    University of Florida, College of Dentistry, Gainesville, Florida, United States
    Eur J Pain 15:118-23. 2011
    ..These findings offer insight into the interactions between biological and psychosocial influences of pain and how these interactions vary by sex...
  48. pmc Testing the relation between dispositional optimism and conditioned pain modulation: does ethnicity matter?
    Burel R Goodin
    Comprehensive Center for Pain Research, University of Florida College of Dentistry, 1395 Center Drive, Dental Tower, Room D2 13, Gainesville, FL 32610, USA
    J Behav Med 36:165-74. 2013
    ..These findings suggest that an optimistic disposition may potentiate endogenous pain inhibition...
  49. pmc Pain-related fear and catastrophizing predict pain intensity and disability independently using an induced muscle injury model
    Jeffrey J Parr
    Comprehensive Center for Pain Research, College of Dentistry, University of Florida, Gainesville, FL 32610, USA
    J Pain 13:370-8. 2012
    ..However, they deviate from the current theoretical model indicating that fear of pain is a consequence of injury and instead suggests that fear of pain before injury may influence reports of pain intensity...
  50. pmc Metallic taste phantom predicts oral pain among 5-year survivors of head and neck cancer
    Henrietta L Logan
    Department of Community Dentistry and Behavioral Science, University of Florida, Room 5192, 1329 SW 16th Street, Gainesville, FL 32610 3628, USA
    Pain 140:323-31. 2008
    ..Routine assessment of oral pain levels could improve current analgesic approaches among head and neck cancer survivors...
  51. ncbi Coronary artery disease and depression: patients with more depressive symptoms have lower cardiovascular reactivity during laboratory-induced mental stress
    Kaki M York
    Cardiovascular Research, Department of Medicine, University of Florida, Gainesville, FL, USA
    Psychosom Med 69:521-8. 2007
    ..Some researchers have proposed that negative outcomes in depressed patients with CAD may be related to exaggerated cardiovascular reactivity and psychological stress. However, the data are unclear...
  52. ncbi Influences of gender role and anxiety on sex differences in temporal summation of pain
    Michael E Robinson
    Department of Clinical and Health Psychology, and McKnight Brain Institute, University of Florida, Gainesville, 32611, USA
    J Pain 5:77-82. 2004
    ..These findings highlight the contribution of social learning factors in the differences between sexes' pain perception...
  53. ncbi Placebo analgesia: friend or foe?
    Donald D Price
    Oral and Maxillofacial Surgery, University of Florida, P O Box 100416, Gainesville, FL 32610 0416, USA
    Curr Rheumatol Rep 8:418-24. 2006
    ..Placebo analgesic effects could be minimized in clinical trials by avoiding these same suggestions and cues...
  54. pmc Modeling genetic imprinting effects of DNA sequences with multilocus polymorphism data
    Sheron Wen
    Department of Statistics, University of Florida, Gainesville, Florida 32611, USA
    Algorithms Mol Biol 4:11. 2009
    ....
  55. ncbi Sex differences in opioid analgesia: clinical and experimental findings
    Roger B Fillingim
    Public Health Services and Research, College of Dentistry, University of Florida, 1600 SW Archer Road, Room D8 44A, P O Box 100404, Gainesville, FL 32610 0404, USA
    Eur J Pain 8:413-25. 2004
    ..Additional investigation is warranted in order to further explicate the nature of sex differences in opioid analgesia and to elucidate the underlying mechanisms...
  56. ncbi Ethnic differences in pain coping: factor structure of the coping strategies questionnaire and coping strategies questionnaire-revised
    Barbara A Hastie
    University of Florida College of Dentistry, Division of Public Health Services and Research, Gainesville 32608, USA
    J Pain 5:304-16. 2004
    ..These findings support the use of the CSQ-R to assess coping in African Americans and in healthy young adults. Additional clinical research is needed to determine the practical importance of group differences in pain coping...
  57. ncbi Mental stress provokes ischemia in coronary artery disease subjects without exercise- or adenosine-induced ischemia
    Srikanth Ramachandruni
    University of Florida, Gainesville, Florida 32608, USA
    J Am Coll Cardiol 47:987-91. 2006
    ..The study population consisted solely of those with negative test results...
  58. pmc Potential psychosocial risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case-control study
    Roger B Fillingim
    University of Florida, College of Dentistry, and North Florida South Georgia Veterans Health System, Gainesville, Florida 32610 3628, USA
    J Pain 12:T46-60. 2011
    ..Findings indicate significant differences between TMD cases and TMD-free controls across multiple psychosocial constructs, and future analyses will determine whether these psychosocial factors increase risk for new onset TMD...
  59. ncbi Spousal responses are differentially associated with clinical variables in women and men with chronic pain
    Roger B Fillingim
    University of Florida College of Dentistry Public Health Services and Research, and North Florida South Georgia VA Health System, Gainesville, Florida 32610, USA
    Clin J Pain 19:217-24. 2003
    ..The present study examined pain reports, medication use, psychosocial factors, functional measures, and pain tolerance in patients with chronic pain...
  60. ncbi Catastrophizing as a mediator of sex differences in pain: differential effects for daily pain versus laboratory-induced pain
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 1 101, Baltimore, MD 21287, USA
    Pain 111:335-41. 2004
    ..These findings highlight the role of catastrophizing in shaping pain responses, as well as illuminating potentially important differences between experimental pain assessment and the clinical experience of pain...
  61. ncbi Catastrophizing predicts changes in thermal pain responses after resolution of acute dental pain
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD 21287, USA
    J Pain 5:164-70. 2004
    ..The use of catastrophizing as a coping strategy might interfere with the resolution of sensitization after cessation of an acutely painful condition, or it might be associated with magnified experimental pain responses across time...
  62. ncbi Sex differences in responses to epidural steroid injection for low back pain
    Sandra L Inman
    College of Nursing, Valdosta State University, Valdosta, Georgia 31698, USA
    J Pain 5:450-7. 2004
    ..These findings suggest that the determinants of ESI pain and treatment outcome might differ across sex...
  63. ncbi Quantitative sensory testing for spinal cord stimulation in patients with chronic neuropathic pain
    Elon Eisenberg
    Pain Relief Unit, Rambam Medical Center, Haifa Pain Research Group, Technion Israel Institute of Technology, Haifa, Israel
    Pain Pract 6:161-5. 2006
    ..Participants: Thirteen patients with radicular leg pain due to failed back surgery syndrome (FBSS) or leg pain due to complex regional pain syndrome (CRPS) who were candidates for SCS...
  64. ncbi Individual differences in diffuse noxious inhibitory controls (DNIC): association with clinical variables
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 1 101, Baltimore, MD 21287, USA
    Pain 106:427-37. 2003
    ..These findings highlight the potential clinical relevance of experimental pain procedures and suggest that DNIC may be the laboratory pain response most closely associated with clinical pain and health-related variables...
  65. ncbi Pain tolerance as a predictor of outcome following multidisciplinary treatment for chronic pain: differential effects as a function of sex
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe St, Meyer 218, Baltimore, MD 21287, USA
    Pain 106:419-26. 2003
    ..These results indicate that experimental pain responses may be most clinically relevant for women, and that sex differences may exist in the determinants of pain-treatment outcomes...
  66. pmc The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans
    Jeffrey S Mogil
    Department of Psychology, McGill University, Montreal, QC, Canada H3A 1B1
    Proc Natl Acad Sci U S A 100:4867-72. 2003
    ....
  67. ncbi Sex differences and incentive effects on perceptual and cardiovascular responses to cold pressor pain
    Daniel Lowery
    Department of Psychology, University of Alabama at Birmingham, USA
    Psychosom Med 65:284-91. 2003
    ....
  68. ncbi Age-related differences in endogenous pain modulation: a comparison of diffuse noxious inhibitory controls in healthy older and younger adults
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 218, Baltimore, MD 21287, USA
    Pain 101:155-65. 2003
    ..If replicated, such findings of reduced pain-modulatory capacity in the elderly may partially explain age-related differences in the prevalence, severity, and impact of chronic pain...
  69. ncbi Re: McCraken et al., A comparison of blacks and whites seeking treatment for chronic pain. Clin J Pain 2001;17:249-55
    Roger B Fillingim
    Clin J Pain 18:136-7. 2002
  70. ncbi Endogenous opioids, blood pressure, and diffuse noxious inhibitory controls: a preliminary study
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Percept Mot Skills 99:679-87. 2004
    ..This relationship, which did not appear opioid-dependent, supports previous models integrating cardiovascular activity with the functioning of pain-modulatory systems...
  71. pmc Ethnic identity predicts experimental pain sensitivity in African Americans and Hispanics
    F Bridgett Rahim-Williams
    University of Florida, College of Dentistry, FL, USA
    Pain 129:177-84. 2007
    ....
  72. ncbi Quantitative assessment of experimental pain perception: multiple domains of clinical relevance
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 1 101, Baltimore, MD 21287, USA
    Pain 114:315-9. 2005
  73. ncbi Overview of orofacial pain: epidemiology and gender differences in orofacial pain
    René M Shinal
    Department of Community Dentistry and Behavioral Science, College of Dentistry, University of Florida, P O Box 103628 Gainesville, FL 32610 3628, USA
    Dent Clin North Am 51:1-18, v. 2007
    ..Efforts to improve our understanding of qualitative sex differences in pain modulation signify a promising step toward developing more tailored approaches to pain management...
  74. pmc Studying sex and gender differences in pain and analgesia: a consensus report
    Joel D Greenspan
    Department of Biomedical Sciences, University of Maryland Dental School, University of Maryland, Baltimore, MD 21201 1510, USA
    Pain 132:S26-45. 2007
    ..as a utilitarian and thought-provoking guide for future research on sex and gender differences in pain and analgesia, both for those currently working in this field as well as those still wondering, "Do I really need to study females?"..
  75. ncbi An interdisciplinary expert consensus statement on assessment of pain in older persons
    Thomas Hadjistavropoulos
    Centre on Aging and Health, University of Regina, Regina, SK, Canada
    Clin J Pain 23:S1-43. 2007
    ..The literature underlying the consensus recommendations is reviewed. Multiple revisions led to final reviews of 2 complete drafts before consensus was reached...
  76. ncbi beta-Endorphin modulates adenosine provoked chest pain in men, but not in women-a comparison between patients with ischemic heart disease and healthy volunteers
    Bita Sadigh
    Department of Cardiology, Karolinska Institute, Karolinska University Hospital Huddinge, Stockholm, Sweden
    Clin J Pain 23:750-5. 2007
    ..Increasing evidence suggests the existence of sex differences in pain perception. Adenosine, an early messenger for myocardial ischemia induces angina pectorislike symptoms in healthy volunteers and in patients with ischemic heart disease...
  77. pmc Self-reported pain sensitivity: lack of correlation with pain threshold and tolerance
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Eur J Pain 11:594-8. 2007
    ..These findings suggest that circumventing psychophysical pain testing by assessing individuals' self-reported pain sensitivity is unlikely to be a useful strategy...
  78. pmc Ethnic differences in diffuse noxious inhibitory controls
    Claudia M Campbell
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 7101, USA
    J Pain 9:759-66. 2008
    ..PERSPECTIVE: This study adds to the growing literature examining ethnic differences in experimental pain perception. Our data suggest that these variations may be influenced by differences in descending inhibition...
  79. ncbi Styles of pain coping predict cardiovascular function following a cold pressor test
    Robert R Edwards
    Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 1 101, Baltimore, MD 21287, USA
    Pain Res Manag 10:219-22. 2005
    ..While many studies have examined the impact of pain-related coping in adjustment to chronic pain, relatively few have evaluated the physiological consequences of differences in pain-coping styles...
  80. ncbi Psychophysical evidence of hypersensitivity in subjects with interstitial cystitis
    Timothy J Ness
    Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Urol 173:1983-7. 2005
    ..We quantified differences in somatic and visceral sensation in healthy subjects and subjects with interstitial cystitis (IC)...
  81. pmc Three major haplotypes of the beta2 adrenergic receptor define psychological profile, blood pressure, and the risk for development of a common musculoskeletal pain disorder
    Luda Diatchenko
    University of North Carolina, Center for Neurosensory Disorders, North Carolina, USA
    Am J Med Genet B Neuropsychiatr Genet 141:449-62. 2006
    ....
  82. ncbi Catastrophizing and experimental pain sensitivity: only in vivo reports of catastrophic cognitions correlate with pain responses
    Robert R Edwards
    Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Pain 6:338-9. 2005
  83. ncbi Menstrual cycle affects bladder pain sensation in subjects with interstitial cystitis
    Tykeysha Powell-Boone
    Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Urol 174:1832-6. 2005
    ..Using psychophysical methods we compared the effect of the menstrual cycle on bladder sensation in subjects with the diagnosis of interstitial cystitis (IC) and in controls...
  84. ncbi What is controlled for in placebo-controlled trials?
    Roger B Fillingim
    Mayo Clin Proc 80:1119-21. 2005
  85. ncbi Idiopathic pain disorders--pathways of vulnerability
    Luda Diatchenko
    Center for Neurosensory Disorders, School of Dentistry, University of North Carolina, Chapel Hill, NC 27514 7455, USA
    Pain 123:226-30. 2006
  86. ncbi The unequal burden of pain: confronting racial and ethnic disparities in pain
    Carmen R Green
    Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA
    Pain Med 4:277-94. 2003
    ..Racial- and ethnic-based differences in the pain care experience have been described. Racial and ethnic minorities tend to be undertreated for pain when compared with non-Hispanic Whites...
  87. ncbi Hyperalgesia versus response bias in fibromyalgia
    Roger B Fillingim
    Pain 105:385-6. 2003
  88. ncbi GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence
    Irmgard Tegeder
    Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, 149 13th Street, Room 4309, Charlestown, Massachusetts 02129, USA
    Nat Med 12:1269-77. 2006
    ..BH4 is therefore an intrinsic regulator of pain sensitivity and chronicity, and the GTP cyclohydrolase haplotype is a marker for these traits...
  89. ncbi Association between estrogen replacement therapy and back pain among postmenopausal women
    Roger B Fillingim
    Spine (Phila Pa 1976) 27:334-5. 2002