Research Topics
| Massimo S FiandacaSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
The use of convection-enhanced delivery with liposomal toxins in neurooncologyMassimo S Fiandaca
Molecular Therapeutics Laboratory, Department of Neurological Surgery, University of California San Francisco, 1855 Folsom Street, Mission Center Building, Rm 226, San Francisco, CA 94103, USA
Toxins (Basel) 3:369-97. 2011..How CED and liposomal technologies may influence future neurooncologic treatments are also considered...
Human/nonhuman primate AC-PC ratio--considerations for translational brain measurementsMassimo S Fiandaca
Movement Disorders Laboratory, Department of Neurological Surgery, University of California San Francisco, 1855 Folsom Street, San Francisco, CA 94103, USA
J Neurosci Methods 196:124-30. 2011....
Gene therapy for Parkinson's disease: from non-human primates to humansMassimo S Fiandaca
University of California San Francisco, Neurosurgery Department, 1855 Folsom Street, Mission Center Building Room 226, San Francisco, CA 94103, USA
Curr Opin Mol Ther 12:519-29. 2010..In this review, the pertinent scientific research related to the use of gene therapy for the treatment of PD is summarized, with a particular focus on the accomplishments and challenges during the past 2 years...
Optimal region of the putamen for image-guided convection-enhanced delivery of therapeutics in human and non-human primatesDali Yin
Department of Neurosurgery, University of California San Francisco, 1855 Folsom Street, MCB 226, San Francisco, CA 94103, USA
Neuroimage 54:S196-203. 2011....
Cannula placement for effective convection-enhanced delivery in the nonhuman primate thalamus and brainstem: implications for clinical delivery of therapeuticsDali Yin
Department of Neurosurgery, University of California, San Francisco, California 94103, USA
J Neurosurg 113:240-8. 2010....
Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson diseaseFrancisco Valles
Movement Disorder Research Program, Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94103, USA
Neurosurgery 67:1377-85. 2010....
Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's diseaseR Mark Richardson
Department of Neurological Surgery, University of California San Francisco, San Francisco, California 94143 0112, USA
Mol Ther 19:1048-57. 2011..The results elucidate the necessary parameters for achieving widespread GDNF expression in the putamenal motor area and afferent substantia nigra of PD patients...
Striatal volume differences between non-human and human primatesDali Yin
Department of Neurosurgery, University of California San Francisco, 1855 Folsom Street, San Francisco, CA 94103, United States
J Neurosci Methods 176:200-5. 2009....
Anatomic compression caused by high-volume convection-enhanced delivery to the brainFrancisco Valles
Movement Disorder Research Program, Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94103, USA
Neurosurgery 65:579-85; discussion 585-6. 2009..This article reports our analysis of CED infusions into normal brains and those compromised by tumors and how monitoring the CED infusion with MRI may be helpful in preventing some complications...
Real-time MR imaging of adeno-associated viral vector delivery to the primate brainMassimo S Fiandaca
Department of Neurological Surgery, University of California San Francisco, 1855 Folsom Street, Room 226, San Francisco, CA 94103, USA
Neuroimage 47:T27-35. 2009..It seems likely that the difference in distribution may be due to differences in tissue specificity of the two serotypes...
Image-guided convection-enhanced delivery platform in the treatment of neurological diseasesMassimo S Fiandaca
Department of Neurological Surgery, University of California San Francisco, San Francisco, California 94103, USA
Neurotherapeutics 5:123-7. 2008..Furthermore, we believe that this image-guided CED platform can be used in other translational neuroscience efforts, with eventual clinical application beyond neuro-oncology and PD...
