C F Ferris

Summary

Affiliation: University of Massachusetts Medical School
Country: USA

Publications

  1. ncbi request reprint Pup suckling is more rewarding than cocaine: evidence from functional magnetic resonance imaging and three-dimensional computational analysis
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 25:149-56. 2005
  2. ncbi request reprint Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, MA, USA
    Pharmacol Biochem Behav 83:169-74. 2006
  3. pmc Activation of neural pathways associated with sexual arousal in non-human primates
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Magn Reson Imaging 19:168-75. 2004
  4. ncbi request reprint Using an animal model to assess the long-term behavioral and biological consequences of adolescent abuse and exposure to alcohol
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Ann N Y Acad Sci 1008:69-78. 2003
  5. pmc Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder
    C F Ferris
    Program in Behavioral Neuroscience, Department of Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA
    BMC Neurosci 2:10. 2001
  6. pmc Functional magnetic resonance imaging in conscious animals: a new tool in behavioural neuroscience research
    C F Ferris
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Neuroendocrinol 18:307-18. 2006
  7. doi request reprint Oxytocin modulates unconditioned fear response in lactating dams: an fMRI study
    Marcelo Febo
    Center for Translational Neuroimaging and Department of Psychology, Northeastern University, Boston, MA, USA
    Brain Res 1302:183-93. 2009
  8. ncbi request reprint Imaging the neural substrates involved in the genesis of pentylenetetrazol-induced seizures
    Mathew E Brevard
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA mathew brevard umassmed edu
    Epilepsia 47:745-54. 2006
  9. ncbi request reprint Vasopressin and developmental onset of flank marking behavior in golden hamsters
    C F Ferris
    Psychiatry Department, University of Massachusetts Medical Center, Worcester 01655, USA
    J Neurobiol 30:192-204. 1996
  10. ncbi request reprint Serotonin regulation of aggressive behavior in male golden hamsters (Mesocricetus auratus)
    C F Ferris
    Department of Psychiatry, University of Massachusetts Medical Center, Worcester 01655, USA
    Behav Neurosci 113:804-15. 1999

Research Grants

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Pup suckling is more rewarding than cocaine: evidence from functional magnetic resonance imaging and three-dimensional computational analysis
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 25:149-56. 2005
    ..These data support the notion that pup stimulation is more reinforcing than cocaine, underscoring the importance of pup seeking over other rewarding stimuli during lactation...
  2. ncbi request reprint Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, MA, USA
    Pharmacol Biochem Behav 83:169-74. 2006
    ....
  3. pmc Activation of neural pathways associated with sexual arousal in non-human primates
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Magn Reson Imaging 19:168-75. 2004
    ..To evaluate brain activity associated with sexual arousal, fully conscious male marmoset monkeys were imaged during presentation of odors that naturally elicit high levels of sexual activity and sexual motivation...
  4. ncbi request reprint Using an animal model to assess the long-term behavioral and biological consequences of adolescent abuse and exposure to alcohol
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Ann N Y Acad Sci 1008:69-78. 2003
    ..Exposure to alcohol as adolescents enhanced aggression in adulthood. These data demonstrate a pronounced difference in behavior and neuroendocrinology between adolescent and adult hamsters in their response to traumatic stress...
  5. pmc Vasopressin-dependent flank marking in golden hamsters is suppressed by drugs used in the treatment of obsessive-compulsive disorder
    C F Ferris
    Program in Behavioral Neuroscience, Department of Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA
    BMC Neurosci 2:10. 2001
    ..The present experiments were carried out to test whether pharmacological agents used to alleviate obsessive compulsive disorder could inhibit arginine vasopressin-induced flank marking and grooming...
  6. pmc Functional magnetic resonance imaging in conscious animals: a new tool in behavioural neuroscience research
    C F Ferris
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01655, USA
    J Neuroendocrinol 18:307-18. 2006
  7. doi request reprint Oxytocin modulates unconditioned fear response in lactating dams: an fMRI study
    Marcelo Febo
    Center for Translational Neuroimaging and Department of Psychology, Northeastern University, Boston, MA, USA
    Brain Res 1302:183-93. 2009
    ....
  8. ncbi request reprint Imaging the neural substrates involved in the genesis of pentylenetetrazol-induced seizures
    Mathew E Brevard
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA mathew brevard umassmed edu
    Epilepsia 47:745-54. 2006
    ....
  9. ncbi request reprint Vasopressin and developmental onset of flank marking behavior in golden hamsters
    C F Ferris
    Psychiatry Department, University of Massachusetts Medical Center, Worcester 01655, USA
    J Neurobiol 30:192-204. 1996
    ..These results suggest that heightened synthesis and release of AVP between P-18 and P-22 may contribute to the developmental onset of flank marking...
  10. ncbi request reprint Serotonin regulation of aggressive behavior in male golden hamsters (Mesocricetus auratus)
    C F Ferris
    Department of Psychiatry, University of Massachusetts Medical Center, Worcester 01655, USA
    Behav Neurosci 113:804-15. 1999
    ..Retrogradely labeled 5-HT neurons were found within the dorsal, median, and caudal linear raphe nuclei and are suspected to inhibit AVP-facilitated offensive aggression by an activation of 5-HT1A receptors in the AH...
  11. ncbi request reprint Functional imaging of brain activity in conscious monkeys responding to sexually arousing cues
    C F Ferris
    Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
    Neuroreport 12:2231-6. 2001
    ....
  12. ncbi request reprint Voluntary ethanol consumption in male adolescent hamsters increases testosterone and aggression
    C F Ferris
    Department of Psychiatry, University of Massachusetts Medical Center, Worcester 01655, USA
    Physiol Behav 63:739-44. 1998
    ..These results suggest that voluntary EtOH exposure during male adolescence has specific neuroendocrine effects with lasting behavioral consequences...
  13. ncbi request reprint Flank-marking behavior and the neural distribution of vasopressin innervation in golden hamsters with suprachiasmatic lesions
    Y Delville
    Psychiatry Department, University of Massachusetts Medical Center, Worcester 01655, USA
    Behav Neurosci 112:1486-501. 1998
    ..95%) depleted from several forebrain areas in SCN-lesioned hamsters, the effect of the lesions was much more limited within the forebrain areas involved in flank-marking behavior as well as within the midbrain and hindbrain...
  14. pmc Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing
    M Febo
    Department of Psychiatry, Center for Comparative NeuroImaging, University of Massachusetts Medical School, 303 Belmont Street, Worcester, MA 01604, USA
    Neuroscience 148:400-12. 2007
    ..Changes in retrieval behavior in cocaine-sensitized mothers might be associated with a hypo-responsive medial PFC...
  15. pmc Hemodynamic and metabolic changes induced by cocaine in anesthetized rat observed with multimodal functional MRI
    Karl F Schmidt
    Center for Comparative NeuroImaging, University of Massachusetts, Worcester, MA, USA
    Psychopharmacology (Berl) 185:479-86. 2006
    ....
  16. ncbi request reprint Early androgen treatment decreases cognitive function and catecholamine innervation in an animal model of ADHD
    J A King
    Department of Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA
    Behav Brain Res 107:35-43. 2000
    ....
  17. ncbi request reprint Adolescent stress alters ethanol ingestion and agonistic behavior in the male golden hamster
    C F Ferris
    Department of Psychiatry, University of Massachusetts Medical Center, Worcester 01655, USA
    Ann N Y Acad Sci 794:348-51. 1996
    ..However, because of the variability between experimental groups, it is necessary to replicate these studies with larger numbers of animals and expand the findings to include blood ETOH concentrations...
  18. pmc Regional cerebral blood flow and BOLD responses in conscious and anesthetized rats under basal and hypercapnic conditions: implications for functional MRI studies
    Kenneth Sicard
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, U S A
    J Cereb Blood Flow Metab 23:472-81. 2003
    ..This study also shows that perfusion and perfusion-based functional MRI can be performed in awake animals...
  19. ncbi request reprint Neural connections of the anterior hypothalamus and agonistic behavior in golden hamsters
    Y Delville
    Program in Neuropsychiatric Sciences, Psychiatry Department, University of Massachusetts Medical Center, Worcester, MA, USA
    Brain Behav Evol 55:53-76. 2000
    ..Vasopressin neurons in the nucleus circularis and medial division of the supraoptic nucleus showed increased neuronal activity in the fighters, supporting their role in the control of offensive aggression...
  20. ncbi request reprint Adolescent stress and neural plasticity in hamsters: a vasopressin-serotonin model of inappropriate aggressive behaviour
    C F Ferris
    Psychiatry Department, University of Massachusetts Medical Center, Worcester 01655, USA
    Exp Physiol 85:85S-90S. 2000
    ....
  21. ncbi request reprint Adolescent anabolic steroid use and aggressive behavior in golden hamsters
    R H Melloni
    Department of Psychiatry, University of Massachusetts Medical Center, Worcester 01655, USA
    Ann N Y Acad Sci 794:372-5. 1996
    ....
  22. ncbi request reprint Imaging brain activity in conscious monkeys following oral MDMA ("ecstasy")
    Mathew E Brevard
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Magn Reson Imaging 24:707-14. 2006
    ..These data identify brain areas and functional circuits sensitive to a recreational dose of MDMA, some of which may be vulnerable to long-term intermittent exposure to this drug...
  23. ncbi request reprint Functional magnetic resonance imaging shows oxytocin activates brain regions associated with mother-pup bonding during suckling
    Marcelo Febo
    Department of Psychiatry, Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 25:11637-44. 2005
    ..The data suggest that oxytocin may strengthen mother-infant bond formation partly by acting through brain areas involved in regulating olfactory discrimination, emotions, and reward...
  24. pmc Cocaine-induced metabolic activation in cortico-limbic circuitry is increased after exposure to the histone deacetylase inhibitor, sodium butyrate
    Marcelo Febo
    Department of Psychology and Center for Translational Neuroimaging, Northeastern University, Boston, MA, USA
    Neurosci Lett 465:267-71. 2009
    ..These findings suggest that HDACi modulation after repeated stimulant exposure involves cortico-limbic circuitry regulating emotion, motivation and memory...
  25. pmc Differential recovery of multimodal MRI and behavior after transient focal cerebral ischemia in rats
    Kenneth M Sicard
    Department of Psychiatry, Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, Massachusetts 01604, USA
    J Cereb Blood Flow Metab 26:1451-62. 2006
    ....
  26. doi request reprint Functional magnetic resonance imaging and the neurobiology of vasopressin and oxytocin
    Craig F Ferris
    Department of Psychology, Center for Translational Imaging, Northeastern University, Boston, MA, USA
    Prog Brain Res 170:305-20. 2008
    ..The data suggest that OXT may strengthen mother-infant bond formation partly by acting through brain areas involved in regulating olfactory discrimination, emotions and reward...
  27. pmc Procedure for minimizing stress for fMRI studies in conscious rats
    Jean A King
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical Center, Worcester, MA 01655, USA
    J Neurosci Methods 148:154-60. 2005
    ..The feasibility of improving the quality of fMRI data acquired in alert rats by utilizing a relatively simple technique is presented...
  28. ncbi request reprint Estrogen influences cocaine-induced blood oxygen level-dependent signal changes in female rats
    Marcelo Febo
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    J Neurosci 25:1132-6. 2005
    ..It is possible that the actions of estrogen within the aforementioned brain regions potentiate the behavioral response to cocaine observed in female rats...
  29. pmc Corticothalamic modulation during absence seizures in rats: a functional MRI assessment
    Jeffrey R Tenney
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School Worcester, Massachusetts 01655, USA
    Epilepsia 44:1133-40. 2003
    ..Functional magnetic resonance imaging (fMRI) was used to identify areas of brain activation during absence seizures in an awake animal model...
  30. pmc FMRI of brain activation in a genetic rat model of absence seizures
    Jeffrey R Tenney
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Epilepsia 45:576-82. 2004
    ..EEG-triggered functional magnetic resonance imaging (fMRI) was used to identify areas of brain activation during spontaneous spike-and-wave discharges (SWDs) in an epileptic rat strain under awake conditions...
  31. ncbi request reprint fMRI of generalized absence status epilepticus in conscious marmoset monkeys reveals corticothalamic activation
    Jeffrey R Tenney
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Epilepsia 45:1240-7. 2004
    ..A nonhuman primate model of generalized absence status epilepticus was developed for use in functional magnetic resonance imaging (fMRI) experiments to elucidate the brain mechanisms underlying this disorder...
  32. pmc Imaging cocaine-induced changes in the mesocorticolimbic dopaminergic system of conscious rats
    Marcelo Febo
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, CCNI Building, 303 Belmont Street, Worcester, MA 01655, USA
    J Neurosci Methods 139:167-76. 2004
    ..These findings demonstrate the technical feasibility of studying psychostimulant-induced brain activity using functional MRI in conscious rats...
  33. pmc Long-term changes of functional MRI-based brain function, behavioral status, and histopathology after transient focal cerebral ischemia in rats
    Kenneth M Sicard
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, 303 Belmont St, Worcester, MA 01604, USA
    Stroke 37:2593-600. 2006
    ..We assessed the evolution of ischemic injury, behavioral status, and brain activity at acute to chronic periods after transient middle cerebral artery occlusion (tMCAO) in rats...
  34. pmc The neural consequences of repeated cocaine exposure revealed by functional MRI in awake rats
    Marcelo Febo
    Psychiatry Department, Center for Comparative NeuroImaging, University of Massachusetts Medical School, Worcester, MA 01604, USA
    Neuropsychopharmacology 30:936-43. 2005
    ..Therefore, the lower metabolic activation in response to cocaine could reflect a reduced neuronal and/or synaptic activity upon repeated administration...
  35. ncbi request reprint Seed finding in golden hamsters: a potential animal model for screening anxiolytic drugs
    Jean A King
    Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA 01655, USA
    Neuropsychobiology 45:150-5. 2002
    ..These data provide evidence that seed finding in hamsters may serve as an animal model for screening potential anxiolytic drugs...
  36. ncbi request reprint Anabolic-androgenic steroid exposure during adolescence and aggressive behavior in golden hamsters
    R H Melloni
    Molecular Neurobiology Laboratory, University of Massachusetts Medical Center, Worcester, MA 01655, USA
    Physiol Behav 61:359-64. 1997
    ..The results of this study show that exposure to AAS during adolescence facilitates aggressive response patterns, but does not alter body weight...
  37. pmc Changes in MRI signal intensity during hypercapnic challenge under conscious and anesthetized conditions
    M E Brevard
    Center for Comparative NeuroImaging, Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, USA
    Magn Reson Imaging 21:995-1001. 2003
    ..In summary, cerebral vasculature appears to be more sensitive to hypercapnic challenge in the conscious condition resulting in enhanced T2* MRI signal intensity and the potential for better BOLD signal changes during functional imaging...
  38. ncbi request reprint A dual RF resonator system for high-field functional magnetic resonance imaging of small animals
    R Ludwig
    Center for Comparative NeuroImaging, Bioengineering Institute and Department of Electrical and Computer Engineering, Worcester Polytechnic Institute, Worcester, MA 01609, USA
    J Neurosci Methods 132:125-35. 2004
    ..Cranial images acquired from fully conscious rats in a 4.7 T Bruker 40 cm bore animal scanner underscore the feasibility of this approach and bode well to extend this system to the imaging of other animals...
  39. ncbi request reprint Diazepam inhibits organophosphate-induced central respiratory depression
    Eric W Dickson
    Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, MA, USA
    Acad Emerg Med 10:1303-6. 2003
    ..However, the exact mechanism of OP-induced CRD is unknown. In these studies, the authors investigated the hypothesis that OP-induced CRD is the result of overstimulation of CNS respiratory centers...
  40. ncbi request reprint Vasopressin/oxytocin and aggression
    Craig F Ferris
    Center for Comparative NeuroImaging, University of Massachusetts Medical School, Medical School, Worcester, MA 01655, USA
    Novartis Found Symp 268:190-8; discussion 198-200, 242-53. 2005
    ..The activity of the vasopressin appears linked to the serotonin system providing a mechanism for enhancing and suppressing aggressive behaviour...
  41. ncbi request reprint Vasopressin antagonists as anxiolytics and antidepressants: recent developments
    Neal G Simon
    Dept of Biological Sciences, Lehigh University, Bethlehem, PA 18015, USA
    Recent Pat CNS Drug Discov 3:77-93. 2008
    ..In this review, the development of compounds in this class since 2005 is considered. The most advanced clinical candidates and newer compounds described in recent patents are presented...
  42. doi request reprint Nursing stimulation is more than tactile sensation: It is a multisensory experience
    Marcelo Febo
    Department of Psychology, Northeastern University, 360 Huntington Avenue 125NI, Boston, MA 02115, USA
    Horm Behav 54:330-9. 2008
    ..Enhanced sensitivity across the cortical mantle during nursing may help the dam to perceive, process, and remember stimuli critical to the care and protection of her young...
  43. ncbi request reprint Confounding effects of volatile anesthesia on CBV assessment in rodent forebrain following ethanol challenge
    Feng Luo
    Experimental Imaging Abbott Laboratories, Abbott Park, Illinois 60064, USA
    J Magn Reson Imaging 26:557-63. 2007
    ..To compare and contrast the pattern and characteristics of the cerebral blood volume (CBV) response to ethanol (EtOH) in rats under awake and anesthetized conditions...
  44. ncbi request reprint Neuroendocrine response to female ovulatory odors depends upon social condition in male common marmosets, Callithrix jacchus
    Toni E Ziegler
    National Primate Research Center, University of Wisconsin Madison, Madison, WI 53715, USA
    Horm Behav 47:56-64. 2005
    ..These results indicate that a rapid hormonal response to sexually arousing cues occurs in marmosets, and the data suggest that a male's social condition influences how he responds to sexually relevant cues...
  45. pmc Azetidinones as vasopressin V1a antagonists
    Christophe D Guillon
    Department of Chemistry, 6 East Packer Avenue, Lehigh University, Bethlehem, PA 18015, USA
    Bioorg Med Chem 15:2054-80. 2007
    ....
  46. pmc Social odours, sexual arousal and pairbonding in primates
    Charles T Snowdon
    Department of Psychology, University of Wisconsin, Madison, WI 53706, USA
    Philos Trans R Soc Lond B Biol Sci 361:2079-89. 2006
    ....
  47. ncbi request reprint Neural effects of MDMA as determined by functional magnetic resonance imaging and magnetic resonance spectroscopy in awake marmoset monkeys
    Jerrold S Meyer
    Department of Psychology, 135 Hicks Way, University of Massachusetts, Amherst, MA 01003, USA
    Ann N Y Acad Sci 1074:365-76. 2006
    ....

Research Grants5

  1. Noninvasive Devices for fMRI Studies in Drug Abuse -II
    Craig Ferris; Fiscal Year: 2004
    ..This technology will greatly enhance preclinical research in developmental neurobiology, neurological diseases, mental illness and drug addiction. ..
  2. Gradient Coils to Enhance MRI Research in Mental Health
    Craig Ferris; Fiscal Year: 2005
    ..The final product design will provide enhanced flexibility and usability, making it possible for the lay scientist to perform imaging on a range of research animals over a wide range of magnet field strengths and bore sizes. ..
  3. Neurobehavioral Effects of MDMA in Adolescent Monkeys
    Craig Ferris; Fiscal Year: 2007
    ..The goal of this work is to better understand the risks of adolescent MDMA exposure on brain function, psychosocial and cognitive development. ..
  4. FUNCTIONAL MRI OF MOTIVATION IN NONHUMAN PRIMATES
    Craig Ferris; Fiscal Year: 2002
    ..There are no effective psychosocial intervention strategies or drug treatments to help violent sex offenders. This is an extremely important area of mental health that impacts on public safety and criminal corrections. ..
  5. ADOLESCENT STRESS AND NEURAL PLASTICITY
    Craig Ferris; Fiscal Year: 2004
    ..This work will help understand the effects of stress in adolescence and the ability of the brain to recover from insult at this potentially vulnerable period of development. ..