Research Topics
Genomes and GenesSpecies | Joseph J FerrettiSummaryAffiliation: University of Oklahoma Health Sciences Center Country: USA Publications
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Detail Information
Publications
Complete genome sequence of an M1 strain of Streptococcus pyogenesJ J Ferretti
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA
Proc Natl Acad Sci U S A 98:4658-63. 2001....
CodY-affected transcriptional gene expression of Streptococcus pyogenes during growth in human bloodHorst Malke
Oklahoma University Health Sciences Center, Department of Microbiology and Immunology, Oklahoma City, OK 73190, USA
J Med Microbiol 56:707-14. 2007....
Genome sequence of a nephritogenic and highly transformable M49 strain of Streptococcus pyogenesW Michael McShan
Department of Pharmaceutical Sciences, University of Oklahoma Health Sciences Center, P O Box 26901, CPB307, Oklahoma City, OK, USA
J Bacteriol 190:7773-85. 2008..Thus, while natural selection favors stability in much of the genome, it favors diversity in these regions...
Dynamics of speB mRNA transcripts in Streptococcus pyogenesZhiyun Chen
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA
J Bacteriol 194:1417-26. 2012..We conclude that the increased speB mRNA stability contributes to the rapid accumulation of speB transcript during growth...
Linking the nutritional status of Streptococcus pyogenes to alteration of transcriptional gene expression: the action of CodY and RelAHorst Malke
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA
Int J Med Microbiol 296:259-75. 2006..Inasmuch as CodY influenced the expression of other regulators (pel/sagA, mga, covRS, ropB, pyrR), its action is amplified and expands the complex regulatory network that governs gene expression in S. pyogenes...
Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogenDragana Ajdic
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
Proc Natl Acad Sci U S A 99:14434-9. 2002....
Autonomous expression of the slo gene of the bicistronic nga-slo operon of Streptococcus pyogenesDragutin J Savic
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA
Infect Immun 70:2730-3. 2002..Finally, we demonstrated that sloR, a S. pyogenes gene that closely resembles the Clostridium perfringens pfoR gene, exerts a negative effect on the expression of the slo gene...
Microbiology. The thin line between gut commensal and pathogenMichael S Gilmore
Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
Science 299:1999-2002. 2003
Novel genomic rearrangement that affects expression of the Streptococcus pyogenes streptolysin O (slo) geneDragutin J Savic
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
J Bacteriol 185:1857-69. 2003..In addition, the product of the recombining DNAs, including the splicing site, does not follow any example of a known recombination mechanism. The implications of this rearrangement for slo expression are discussed...
Comparative genomics of streptococcal speciesJoseph J Ferretti
Department of Microbiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 73190, USA
Indian J Med Res 119:1-6. 2004..Comparative genome analysis between the species showed that S. pyogenes was more closely related to S. agalactiae than with S. pneumoniae or S. mutans...
Sequence analysis and expression in Escherichia coli of the hyaluronidase gene of Streptococcus pyogenes bacteriophage H4489AW L Hynes
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City 73190
Infect Immun 57:533-9. 1989..Controlled exclusive expression of the hylP gene via the T7 polymerase-promoter system in E. coli resulted in a 40,000-dalton protein, a result consistent with the coding capacity of the hylP gene...
Analysis of a second bacteriophage hyaluronidase gene from Streptococcus pyogenes: evidence for a third hyaluronidase involved in extracellular enzymatic activityW L Hynes
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City 73190, USA
Infect Immun 63:3015-20. 1995..These results suggest the presence of a different hyaluronidase gene encoding a protein that is actively secreted into the extracellular milieu...
Cloning of the gene encoding Streptococcin A-FF22, a novel lantibiotic produced by Streptococcus pyogenes, and determination of its nucleotide sequenceW L Hynes
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City 73190
Appl Environ Microbiol 59:1969-71. 1993..The proteolytic processing site of the SA-FF22 prepeptide differs from that which characterizes other type A lantibiotics...
Temporal production of streptococcal erythrogenic toxin B (streptococcal cysteine proteinase) in response to nutrient depletionM S Chaussee
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City 73190, USA
Infect Immun 65:1956-9. 1997..Additionally, SPE B production was inhibited when the concentration of glucose in the medium was maintained. These results suggest that SPE B is secreted under conditions of starvation and may be involved in nutrient acquisition...
The NAD-glycohydrolase (nga) gene of Streptococcus pyogenesD Ajdic
Department of Microbiology and Immunology, University of Oklahoma, Health Sciences Center, Oklahoma City, OK 73104, USA
FEMS Microbiol Lett 191:235-41. 2000..In contrast, 92% of strains isolated from patients with invasive streptococcal infections were positive for NADase production...
Nucleotide sequence of the streptococcin A-FF22 lantibiotic regulon: model for production of the lantibiotic SA-FF22 by strains of Streptococcus pyogenesR E McLaughlin
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, USA
FEMS Microbiol Lett 175:171-7. 1999..Located immediately downstream of the scn region is a putative transposase gene, the presence of which supports earlier data that indicated a mobile nature to this region...
Identification, cloning, and expression of the CAMP factor gene (cfa) of group A streptococciK Gase
Department of Microbiology and Immunology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA
Infect Immun 67:4725-31. 1999..The results presented here, along with previous reports, indicate that the CAMP factor gene is fairly widespread among streptococci, being present at least in groups A, B, C, G, M, P, R, and U...
Construction of a GBS-GAS DNA subtraction library allows discovery of previously unidentified GBS genes and rapid location of unique regions on the GBS chromosomeAlexander N Suvorov
Institute of Experimental Medicine, Academy of Medical Sciences, Pavlova 12, St Petersburg 197376, Russia
J Basic Microbiol 44:66-74. 2004..Inserts from 21 clones were labeled and used as probes for hybridization with GBS DNA fragments separated by pulsed field electrophoresis. A genetic map of GBS strain O9OR was constructed...
Genome analysis of an inducible prophage and prophage remnants integrated in the Streptococcus pyogenes strain SF370Carlos Canchaya
, Nestec Ltd. Vers-chez-les-Blanc, CH Lausanne 26, Switzerland
Virology 302:245-58. 2002..1 and S. pneumoniae phage MM1 integrated into homologous chromosomal locations. The prophage sequences were interpreted with a hypothesis that predicts elements of cooperation and an arms race between phage and host genomes...
