Peter Ferrazzano

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Age-dependent microglial activation in immature brains after hypoxia- ischemia
    Peter Ferrazzano
    Department of Pediatrics, University of Wisconsin Medical School, 1500 Highland Ave, Madison, WI 53705, USA
    CNS Neurol Disord Drug Targets 12:338-49. 2013
  2. pmc Inhibiting the Na+/H+ exchanger reduces reperfusion injury: a small animal MRI study
    Peter Ferrazzano
    Department of Pediatrics, University of Wisconsin, Madison, WI 53792, USA
    Front Biosci (Elite Ed) 3:81-8. 2011
  3. pmc TrkB receptor agonist 7, 8 dihydroxyflavone triggers profound gender- dependent neuroprotection in mice after perinatal hypoxia and ischemia
    Kutluay Uluc
    Department of Pediatrics, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI 53705, USA
    CNS Neurol Disord Drug Targets 12:360-70. 2013
  4. pmc Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains
    Yejie Shi
    Department of Neurological Surgery, University of Wisconsin, Madison, Wisconsin, USA
    J Neurochem 119:124-35. 2011
  5. pmc Inhibition of Na+/H+ exchanger isoform 1 is neuroprotective in neonatal hypoxic ischemic brain injury
    Pelin Cengiz
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Antioxid Redox Signal 14:1803-13. 2011
  6. pmc Sustained Na(+)/H(+) Exchanger Activation Promotes Gliotransmitter Release from Reactive Hippocampal Astrocytes following Oxygen-Glucose Deprivation
    Pelin Cengiz
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America Department of Waisman Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
    PLoS ONE 9:e84294. 2014
  7. pmc Stimulation of Na(+)/H(+) exchanger isoform 1 promotes microglial migration
    Yejie Shi
    Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    PLoS ONE 8:e74201. 2013
  8. pmc Chronic neurological deficits in mice after perinatal hypoxia and ischemia correlate with hemispheric tissue loss and white matter injury detected by MRI
    Pelin Cengiz
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Dev Neurosci 33:270-9. 2011
  9. pmc Excessive Na+/H+ exchange in disruption of dendritic Na+ and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia
    Douglas B Kintner
    Department of Neurological Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA
    J Biol Chem 285:35155-68. 2010
  10. pmc Diffusion tensor MRI of spinal decompression sickness
    Elizabeth B Hutchinson
    Department of Neurology, University of Wisconsin, UW Medical Foundation Centennial Building, Madison, Wisconsin, USA
    Undersea Hyperb Med 40:23-31. 2013

Collaborators

Detail Information

Publications10

  1. pmc Age-dependent microglial activation in immature brains after hypoxia- ischemia
    Peter Ferrazzano
    Department of Pediatrics, University of Wisconsin Medical School, 1500 Highland Ave, Madison, WI 53705, USA
    CNS Neurol Disord Drug Targets 12:338-49. 2013
    ..Taken together, compared to P30 mice, P9 mice demonstrated differences in microglial activation and pro-inflammatory responses after HI, which may be important in brain damage and tissue repair...
  2. pmc Inhibiting the Na+/H+ exchanger reduces reperfusion injury: a small animal MRI study
    Peter Ferrazzano
    Department of Pediatrics, University of Wisconsin, Madison, WI 53792, USA
    Front Biosci (Elite Ed) 3:81-8. 2011
    ..The results of this study demonstrate the therapeutic potential for inhibition of NHE-1 in treating cerebral ischemia...
  3. pmc TrkB receptor agonist 7, 8 dihydroxyflavone triggers profound gender- dependent neuroprotection in mice after perinatal hypoxia and ischemia
    Kutluay Uluc
    Department of Pediatrics, University of Wisconsin Madison, School of Medicine and Public Health, Madison, WI 53705, USA
    CNS Neurol Disord Drug Targets 12:360-70. 2013
    ....
  4. pmc Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains
    Yejie Shi
    Department of Neurological Surgery, University of Wisconsin, Madison, Wisconsin, USA
    J Neurochem 119:124-35. 2011
    ..Taken together, our results demonstrate that NHE-1 protein was abundantly expressed in activated microglia and astrocytes. NHE-1 inhibition reduced microglial proinflammatory activation following ischemia...
  5. pmc Inhibition of Na+/H+ exchanger isoform 1 is neuroprotective in neonatal hypoxic ischemic brain injury
    Pelin Cengiz
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Antioxid Redox Signal 14:1803-13. 2011
    ..These findings suggest that NHE-1-mediated disruption of ionic homeostasis contributes to striatal and CA1 pyramidal neuronal injury after neonatal HI...
  6. pmc Sustained Na(+)/H(+) Exchanger Activation Promotes Gliotransmitter Release from Reactive Hippocampal Astrocytes following Oxygen-Glucose Deprivation
    Pelin Cengiz
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America Department of Waisman Center, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, United States of America
    PLoS ONE 9:e84294. 2014
    ..Therefore, blocking sustained NHE1 activation in reactive astrocytes may provide neuroprotection following HI. ..
  7. pmc Stimulation of Na(+)/H(+) exchanger isoform 1 promotes microglial migration
    Yejie Shi
    Department of Neurology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    PLoS ONE 8:e74201. 2013
    ..In addition, NHE-1 and NCXrev play a concerted role in BK-induced microglial migration via Na(+) and Ca(2+) signaling. ..
  8. pmc Chronic neurological deficits in mice after perinatal hypoxia and ischemia correlate with hemispheric tissue loss and white matter injury detected by MRI
    Pelin Cengiz
    Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Dev Neurosci 33:270-9. 2011
    ..T(2)-weighted MRI and DTI are useful indicators of functional outcome after perinatal HI...
  9. pmc Excessive Na+/H+ exchange in disruption of dendritic Na+ and Ca2+ homeostasis and mitochondrial dysfunction following in vitro ischemia
    Douglas B Kintner
    Department of Neurological Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, USA
    J Biol Chem 285:35155-68. 2010
    ..Taken together, our study demonstrates that NHE-1-mediated Na(+) entry and subsequent Na(+)/Ca(2+) exchange activation contribute to the selective dendritic vulnerability to in vitro ischemia...
  10. pmc Diffusion tensor MRI of spinal decompression sickness
    Elizabeth B Hutchinson
    Department of Neurology, University of Wisconsin, UW Medical Foundation Centennial Building, Madison, Wisconsin, USA
    Undersea Hyperb Med 40:23-31. 2013
    ..To our knowledge, this is the first study to demonstrate the utility of DTI for the investigation of DCS-related injury and to define DTI biomarkers of spinal DCS...