Jane F Ferguson

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi request reprint Dietary isoflavone intake is associated with evoked responses to inflammatory cardiometabolic stimuli and improved glucose homeostasis in healthy volunteers
    J F Ferguson
    Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Nutr Metab Cardiovasc Dis 24:996-1003. 2014
  2. pmc Translational studies of lipoprotein-associated phospholipase A₂ in inflammation and atherosclerosis
    Jane F Ferguson
    Cardiovascular Institute, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6160, USA
    J Am Coll Cardiol 59:764-72. 2012
  3. pmc Race and gender variation in response to evoked inflammation
    Jane F Ferguson
    Cardiovascular Institute, Perelman School of Medicine, at the University of Pennsylvania, 11 136 Smilow Center for Translational Research, Building 421, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA
    J Transl Med 11:63. 2013
  4. pmc A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial
    Nehal N Mehta
    Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    J Transl Med 10:124. 2012
  5. pmc Genetics of coronary artery calcification among African Americans, a meta-analysis
    Mary K Wojczynski
    Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA
    BMC Med Genet 14:75. 2013
  6. pmc Insulin sensitivity index in type 1 diabetes and following human islet transplantation: comparison of the minimal model to euglycemic clamp measures
    Michael R Rickels
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    Am J Physiol Endocrinol Metab 306:E1217-24. 2014
  7. pmc Tissue-specific RNA-Seq in human evoked inflammation identifies blood and adipose LincRNA signatures of cardiometabolic diseases
    Yichuan Liu
    From the Departments of Biostatistics and Epidemiology and Biology, Cardiovascular Institute, Perelman School of Medicine and School of Arts and Science at the University of Pennsylvania, Philadelphia
    Arterioscler Thromb Vasc Biol 34:902-12. 2014
  8. pmc Fractalkine is a novel human adipochemokine associated with type 2 diabetes
    Rachana Shah
    Division of Pediatric Endocrinology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Diabetes 60:1512-8. 2011
  9. pmc PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution
    Yu Hu
    Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA and Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
    Nucleic Acids Res 42:e20. 2014
  10. pmc Peroxisome Proliferator-Activated Receptor-α Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia
    Claire K Mulvey
    Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA C K M, J F F, J T M, S K, R Y S, P N P, M H U U, N N M, M P R
    J Am Heart Assoc 1:e002923. 2012

Detail Information

Publications16

  1. ncbi request reprint Dietary isoflavone intake is associated with evoked responses to inflammatory cardiometabolic stimuli and improved glucose homeostasis in healthy volunteers
    J F Ferguson
    Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Nutr Metab Cardiovasc Dis 24:996-1003. 2014
    ....
  2. pmc Translational studies of lipoprotein-associated phospholipase A₂ in inflammation and atherosclerosis
    Jane F Ferguson
    Cardiovascular Institute, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6160, USA
    J Am Coll Cardiol 59:764-72. 2012
    ..This study sought to examine the role of lipoprotein-associated phospholipase A₂ (Lp-PLA₂/PLA2G7) in human inflammation and coronary atherosclerosis...
  3. pmc Race and gender variation in response to evoked inflammation
    Jane F Ferguson
    Cardiovascular Institute, Perelman School of Medicine, at the University of Pennsylvania, 11 136 Smilow Center for Translational Research, Building 421, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA
    J Transl Med 11:63. 2013
    ..Our objective was to examine race and gender influence on the response to experimental endotoxemia...
  4. pmc A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial
    Nehal N Mehta
    Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    J Transl Med 10:124. 2012
    ....
  5. pmc Genetics of coronary artery calcification among African Americans, a meta-analysis
    Mary K Wojczynski
    Department of Genetics, Division of Statistical Genomics, Washington University School of Medicine, St Louis, MO, USA
    BMC Med Genet 14:75. 2013
    ..African Americans (AA) have higher rates of CHD but are less well-studied in genomic studies. We assembled the largest AA data resource currently available with measured CAC to identify associated genetic variants...
  6. pmc Insulin sensitivity index in type 1 diabetes and following human islet transplantation: comparison of the minimal model to euglycemic clamp measures
    Michael R Rickels
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    Am J Physiol Endocrinol Metab 306:E1217-24. 2014
    ..That the minimal model SIC is highly correlated to the clamp-derived measures indicates that the FSIGT is an appropriate methodology for the determination of insulin sensitivity in T1D and following islet transplantation. ..
  7. pmc Tissue-specific RNA-Seq in human evoked inflammation identifies blood and adipose LincRNA signatures of cardiometabolic diseases
    Yichuan Liu
    From the Departments of Biostatistics and Epidemiology and Biology, Cardiovascular Institute, Perelman School of Medicine and School of Arts and Science at the University of Pennsylvania, Philadelphia
    Arterioscler Thromb Vasc Biol 34:902-12. 2014
    ....
  8. pmc Fractalkine is a novel human adipochemokine associated with type 2 diabetes
    Rachana Shah
    Division of Pediatric Endocrinology, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
    Diabetes 60:1512-8. 2011
    ..Fractalkine (CX3CL1) and its receptor (CX3CR1) comprise a chemokine system involved in leukocyte recruitment and adhesion in atherosclerosis, but its role in adipose inflammation and type 2 diabetes is unknown...
  9. pmc PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution
    Yu Hu
    Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA and Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
    Nucleic Acids Res 42:e20. 2014
    ..Our results indicate superior performance of PennSeq over existing methods, particularly for isoforms demonstrating severe non-uniformity. PennSeq is freely available for download at http://sourceforge.net/projects/pennseq. ..
  10. pmc Peroxisome Proliferator-Activated Receptor-α Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia
    Claire K Mulvey
    Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA C K M, J F F, J T M, S K, R Y S, P N P, M H U U, N N M, M P R
    J Am Heart Assoc 1:e002923. 2012
    ....
  11. pmc Omega-3 PUFA supplementation and the response to evoked endotoxemia in healthy volunteers
    Jane F Ferguson
    Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Mol Nutr Food Res 58:601-13. 2014
    ..However, findings in clinical studies are conflicting. We hypothesized that n-3 PUFA supplementation would dose-dependently reduce the systemic inflammatory response to experimental endotoxemia in healthy humans...
  12. pmc The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels
    Nehal N Mehta
    Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Penn Tower, 6th Floor, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA
    Eur Heart J 32:963-71. 2011
    ..Therefore, we examined the relationship between these two SNPs and plasma CXCL12 levels...
  13. pmc Evaluating the impact of sequencing depth on transcriptome profiling in human adipose
    Yichuan Liu
    Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 8:e66883. 2013
    ..Our results suggest that a much higher sequencing depth is needed to reliably identify DAS events than for DE genes. ..
  14. pmc Candidate gene association study of coronary artery calcification in chronic kidney disease: findings from the CRIC study (Chronic Renal Insufficiency Cohort)
    Jane F Ferguson
    Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    J Am Coll Cardiol 62:789-98. 2013
    ..This study sought to identify loci for coronary artery calcification (CAC) in patients with chronic kidney disease (CKD)...
  15. pmc Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies
    Muredach P Reilly
    Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA 19104 6160, USA
    Lancet 377:383-92. 2011
    ..We tested whether genetic factors distinctly contribute to either development of coronary atherosclerosis or, specifically, to myocardial infarction in existing coronary atherosclerosis...
  16. pmc Improvement in insulin sensitivity after human islet transplantation for type 1 diabetes
    Michael R Rickels
    MD, MS, Perelman School of Medicine at the University of Pennsylvania, 12 134 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, Pennsylvania 19104
    J Clin Endocrinol Metab 98:E1780-5. 2013
    ..However, current immunosuppression regimens containing tacrolimus and sirolimus have been shown to induce insulin resistance in rodents...