A P Feranchak

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi Phosphatidylinositol 3-kinase contributes to cell volume regulation through effects on ATP release
    A P Feranchak
    Departments of Pediatrics and Medicine, Children s Hospital and the University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 273:14906-11. 1998
  2. ncbi Hepatobiliary complications of cystic fibrosis
    Andrew P Feranchak
    Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children s Hospital and the University of Colorado Health Sciences Center, 1056 East 19th Avenue, B290, Denver, CO 80218, USA
    Curr Gastroenterol Rep 6:231-9. 2004
  3. ncbi Ion channels in digestive health and disease
    Andrew P Feranchak
    Department of Pediatrics, Children's Hospital and the University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Pediatr Gastroenterol Nutr 37:230-41. 2003
  4. ncbi Adenosine triphosphate release and purinergic regulation of cholangiocyte transport
    Andrew P Feranchak
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Semin Liver Dis 22:251-62. 2002
  5. ncbi Cholangiocyte biology and cystic fibrosis liver disease
    A P Feranchak
    Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children s Hospital and the University of Colorado Health Sciences Center, Denver, Colorado 80218, USA
    Semin Liver Dis 21:471-88. 2001
  6. ncbi p38 MAP kinase modulates liver cell volume through inhibition of membrane Na+ permeability
    A P Feranchak
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Clin Invest 108:1495-504. 2001
  7. ncbi Calcium-dependent regulation of secretion in biliary epithelial cells: the role of apamin-sensitive SK channels
    Andrew P Feranchak
    University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, Colorado 80262, USA
    Gastroenterology 127:903-13. 2004
  8. ncbi The lipid products of phosphoinositide 3-kinase contribute to regulation of cholangiocyte ATP and chloride transport
    A P Feranchak
    Department of Pediatrics, Children s Hospital, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 274:30979-86. 1999
  9. ncbi Volume-sensitive purinergic signaling in human hepatocytes
    A P Feranchak
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    J Hepatol 33:174-82. 2000
  10. ncbi Evidence for Gd(3+) inhibition of membrane ATP permeability and purinergic signaling
    R M Roman
    Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Physiol 277:G1222-30. 1999

Detail Information

Publications21

  1. ncbi Phosphatidylinositol 3-kinase contributes to cell volume regulation through effects on ATP release
    A P Feranchak
    Departments of Pediatrics and Medicine, Children s Hospital and the University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 273:14906-11. 1998
    ..These findings indicate that PI 3-kinase plays a significant role in regulation of cell volume and suggest that the effects are mediated in part through modulation of cellular ATP release...
  2. ncbi Hepatobiliary complications of cystic fibrosis
    Andrew P Feranchak
    Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children s Hospital and the University of Colorado Health Sciences Center, 1056 East 19th Avenue, B290, Denver, CO 80218, USA
    Curr Gastroenterol Rep 6:231-9. 2004
    ..This review focuses on the pathogenesis, clinical manifestations, screening, diagnosis, and treatment of CF hepatobiliary disease...
  3. ncbi Ion channels in digestive health and disease
    Andrew P Feranchak
    Department of Pediatrics, Children's Hospital and the University of Colorado Health Sciences Center, Denver, CO 80262, USA
    J Pediatr Gastroenterol Nutr 37:230-41. 2003
  4. ncbi Adenosine triphosphate release and purinergic regulation of cholangiocyte transport
    Andrew P Feranchak
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Semin Liver Dis 22:251-62. 2002
    ..This article highlights important developments in our understanding of the role of purinergic signaling in cholangiocyte transport and bile formation...
  5. ncbi Cholangiocyte biology and cystic fibrosis liver disease
    A P Feranchak
    Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children s Hospital and the University of Colorado Health Sciences Center, Denver, Colorado 80218, USA
    Semin Liver Dis 21:471-88. 2001
    ..Data on the pathogenesis, prevalence, clinical course, and treatment of CF liver disease will be reviewed...
  6. ncbi p38 MAP kinase modulates liver cell volume through inhibition of membrane Na+ permeability
    A P Feranchak
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Clin Invest 108:1495-504. 2001
    ..Thus, functional interactions between p38 MAP kinase and ion channels may represent an important target for modifying volume-sensitive liver functions...
  7. ncbi Calcium-dependent regulation of secretion in biliary epithelial cells: the role of apamin-sensitive SK channels
    Andrew P Feranchak
    University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, Colorado 80262, USA
    Gastroenterology 127:903-13. 2004
    ..We have identified a Ca 2+ -activated K + channel (SK2) in biliary epithelium that is inhibited by apamin. The purpose of the present studies was to define the role of SK channels in Ca 2+ -dependent cholangiocyte secretion...
  8. ncbi The lipid products of phosphoinositide 3-kinase contribute to regulation of cholangiocyte ATP and chloride transport
    A P Feranchak
    Department of Pediatrics, Children s Hospital, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 274:30979-86. 1999
    ..Taken together, these findings indicate that volume-sensitive activation of PI 3-kinase and the generation of lipid messengers modulate cholangiocyte ATP release, Cl(-) secretion, and, hence, bile formation...
  9. ncbi Volume-sensitive purinergic signaling in human hepatocytes
    A P Feranchak
    Department of Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    J Hepatol 33:174-82. 2000
    ....
  10. ncbi Evidence for Gd(3+) inhibition of membrane ATP permeability and purinergic signaling
    R M Roman
    Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Physiol 277:G1222-30. 1999
    ....
  11. ncbi ClC-2 chloride channels contribute to HTC cell volume homeostasis
    R M Roman
    Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Physiol Gastrointest Liver Physiol 280:G344-53. 2001
    ..These studies provide further evidence that mammalian ClC-2 channel proteins are functional and suggest that in HTC cells they contribute to physiological changes in membrane Cl(-) permeability and cell volume homeostasis...
  12. ncbi Endogenous ATP release regulates Cl- secretion in cultured human and rat biliary epithelial cells
    R M Roman
    Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Physiol 276:G1391-400. 1999
    ..These findings indicate that modulation of ATP release by the cellular hydration state represents a potential signal coordinating cell volume with membrane Cl- permeability and transepithelial Cl- secretion...
  13. ncbi Evidence for multidrug resistance-1 P-glycoprotein-dependent regulation of cellular ATP permeability
    R M Roman
    Department of Medicine, University of Colorado Health Sciences Center, Campus Box B-158, Denver, CO 80262, USA
    J Membr Biol 183:165-73. 2001
    ....
  14. ncbi Ezrin-radixin-moesin-binding phosphoprotein 50 is expressed at the apical membrane of rat liver epithelia
    L Fouassier
    Division of Gastroenterology and Hepatology, University of Colorado Health Sciences Center, Denver, 80262, USA
    Hepatology 33:166-76. 2001
    ....
  15. ncbi Thinking outside the cell: the role of extracellular adenosine triphosphate in bile formation
    Andrew P Feranchak
    Gastroenterology 133:1726-8. 2007
  16. ncbi Purinergic regulation of cholangiocyte secretion: identification of a novel role for P2X receptors
    R Brian Doctor
    UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Am J Physiol Gastrointest Liver Physiol 288:G779-86. 2005
    ..Functional studies indicate that P2X4 is likely the primary isoform involved, representing a novel and functionally important component of the purinergic signaling complex modulating biliary secretion...
  17. ncbi Volume-sensitive tyrosine kinases regulate liver cell volume through effects on vesicular trafficking and membrane Na+ permeability
    Andrew P Feranchak
    Department of Pediatrics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Biol Chem 278:44632-8. 2003
    ....
  18. ncbi Molecular characterization of volume-sensitive SK(Ca) channels in human liver cell lines
    Richard Roman
    Department of Medicine, School of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Physiol Gastrointest Liver Physiol 282:G116-22. 2002
    ..Accordingly, the hSK2 protein is a potential target for pharmacological modulation of liver transport and metabolism through effects on membrane K(+) permeability...
  19. ncbi Comparison of indices of vitamin A status in children with chronic liver disease
    Andrew P Feranchak
    Pediatric Liver Center and Liver Transplantation Program, Section of Pediatric Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics, The Children s Hospital, Denver, CO, USA
    Hepatology 42:782-92. 2005
    ..Our data suggest that serum retinol level as an initial screen followed by confirmation with a modified oral RDR test is the most effective means of identifying vitamin A deficiency in these subjects...
  20. ncbi Fluid flow induces mechanosensitive ATP release, calcium signalling and Cl- transport in biliary epithelial cells through a PKCzeta-dependent pathway
    Kangmee Woo
    UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9063, USA
    J Physiol 586:2779-98. 2008
    ....
  21. ncbi Evidence-based practice recommendations for nutrition-related management of children and adults with cystic fibrosis and pancreatic insufficiency: results of a systematic review
    Virginia A Stallings
    Division of Gastroenterology, Hepatology, and Nutrition, The Children s Hospital of Philadelphia, 3535 Market St, Philadelphia, PA 19104, USA
    J Am Diet Assoc 108:832-9. 2008
    ..These Registry data-based recommendations are presented...