Christine Fennema-Notestine

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Mental health outcomes in HIV and childhood maltreatment: a systematic review
    Georgina Spies
    South African Research Chairs Initiative SARChI, PTSD Program, Francie van Zijl Drive, Department of Psychiatry, University of Stellenbosch, Cape Town, 7505, South Africa
    Syst Rev 1:30. 2012
  2. pmc Increases in brain white matter abnormalities and subcortical gray matter are linked to CD4 recovery in HIV infection
    Christine Fennema-Notestine
    Department of Psychiatry, University of California, San Diego, CA 92093 0738, USA
    J Neurovirol 19:393-401. 2013
  3. pmc Impact of childhood trauma on functionality and quality of life in HIV-infected women
    Zyrhea C E Troeman
    South African Research Chairs Initiative SARChI, PTSD Program, Department of Psychiatry, University of Stellenbosch, Cape Town, South Africa
    Health Qual Life Outcomes 9:84. 2011
  4. ncbi request reprint Feasibility of multi-site clinical structural neuroimaging studies of aging using legacy data
    Christine Fennema-Notestine
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive 0841, La Jolla, CA 92093 0841, USA
    Neuroinformatics 5:235-45. 2007
  5. pmc Presence of ApoE ε4 allele associated with thinner frontal cortex in middle age
    Christine Fennema-Notestine
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0738, USA
    J Alzheimers Dis 26:49-60. 2011
  6. ncbi request reprint In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease
    C Fennema-Notestine
    Veterans Affairs San Diego Healthcare System, CA, USA
    Neurology 63:989-95. 2004
  7. pmc Structural MRI biomarkers for preclinical and mild Alzheimer's disease
    Christine Fennema-Notestine
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0841, USA
    Hum Brain Mapp 30:3238-53. 2009
  8. pmc Structural neuroimaging in the detection and prognosis of pre-clinical and early AD
    Christine Fennema-Notestine
    Deptartment of Psychiatry, University of California San Diego, San Diego, CA, USA
    Behav Neurol 21:3-12. 2009
  9. pmc Longer term improvement in neurocognitive functioning and affective distress among methamphetamine users who achieve stable abstinence
    Jennifer E Iudicello
    Department of Psychiatry, HIV Neurobehavioral Research Center, University of California, San Diego, School of Medicine, La Jolla, CA 92103, USA
    J Clin Exp Neuropsychol 32:704-18. 2010
  10. pmc Clinical factors related to brain structure in HIV: the CHARTER study
    Terry L Jernigan
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive M C 0115, La Jolla, CA, USA
    J Neurovirol 17:248-57. 2011

Detail Information

Publications84

  1. pmc Mental health outcomes in HIV and childhood maltreatment: a systematic review
    Georgina Spies
    South African Research Chairs Initiative SARChI, PTSD Program, Francie van Zijl Drive, Department of Psychiatry, University of Stellenbosch, Cape Town, 7505, South Africa
    Syst Rev 1:30. 2012
    ..The present systematic review assessed mental health outcomes in HIV-positive individuals who were victims of childhood maltreatment...
  2. pmc Increases in brain white matter abnormalities and subcortical gray matter are linked to CD4 recovery in HIV infection
    Christine Fennema-Notestine
    Department of Psychiatry, University of California, San Diego, CA 92093 0738, USA
    J Neurovirol 19:393-401. 2013
    ..The association of increasing abnormal WM and subcortical GM volumes with CD4+ T cell recovery suggests that neuroinflammation may be one mechanism in CNS pathogenesis. ..
  3. pmc Impact of childhood trauma on functionality and quality of life in HIV-infected women
    Zyrhea C E Troeman
    South African Research Chairs Initiative SARChI, PTSD Program, Department of Psychiatry, University of Stellenbosch, Cape Town, South Africa
    Health Qual Life Outcomes 9:84. 2011
    ..While there are many published studies on HIV and functional limitations, there are few in the context of early abuse and its impact on functionality and Quality of Life (QoL) in HIV...
  4. ncbi request reprint Feasibility of multi-site clinical structural neuroimaging studies of aging using legacy data
    Christine Fennema-Notestine
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive 0841, La Jolla, CA 92093 0841, USA
    Neuroinformatics 5:235-45. 2007
    ..These expected findings support the feasibility of combining legacy data to investigate novel scientific questions...
  5. pmc Presence of ApoE ε4 allele associated with thinner frontal cortex in middle age
    Christine Fennema-Notestine
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 0738, USA
    J Alzheimers Dis 26:49-60. 2011
    ..Ongoing follow-up of the VETSA sample may shed light on the potential for age- and disease-related mediation of the influence of ApoE allele status...
  6. ncbi request reprint In vivo evidence of cerebellar atrophy and cerebral white matter loss in Huntington disease
    C Fennema-Notestine
    Veterans Affairs San Diego Healthcare System, CA, USA
    Neurology 63:989-95. 2004
    ..To investigate the regional pattern of white matter and cerebellar changes, as well as subcortical and cortical changes, in Huntington disease (HD) using morphometric analyses of structural MRI...
  7. pmc Structural MRI biomarkers for preclinical and mild Alzheimer's disease
    Christine Fennema-Notestine
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0841, USA
    Hum Brain Mapp 30:3238-53. 2009
    ..These methods will enable a more complete longitudinal characterization and allow us to identify changes that are predictive of conversion to AD...
  8. pmc Structural neuroimaging in the detection and prognosis of pre-clinical and early AD
    Christine Fennema-Notestine
    Deptartment of Psychiatry, University of California San Diego, San Diego, CA, USA
    Behav Neurol 21:3-12. 2009
    ....
  9. pmc Longer term improvement in neurocognitive functioning and affective distress among methamphetamine users who achieve stable abstinence
    Jennifer E Iudicello
    Department of Psychiatry, HIV Neurobehavioral Research Center, University of California, San Diego, School of Medicine, La Jolla, CA 92103, USA
    J Clin Exp Neuropsychol 32:704-18. 2010
    ..These results suggest partial recovery of neuropsychological functioning and improvement in affective distress upon sustained abstinence from MA that may extend beyond a year or more...
  10. pmc Clinical factors related to brain structure in HIV: the CHARTER study
    Terry L Jernigan
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive M C 0115, La Jolla, CA, USA
    J Neurovirol 17:248-57. 2011
    ..Brain structural integrity in HIV likely reflects dynamic effects of current immune status and HIV replication, superimposed on residual effects associated with severe prior immunosuppression...
  11. pmc The semantic relatedness of cue-intention pairings influences event-based prospective memory failures in older adults with HIV infection
    Steven Paul Woods
    HIV Neurobehavioral Research Center, Department of Psychiatry, University of California, San Diego, CA 92103, USA
    J Clin Exp Neuropsychol 32:398-407. 2010
    ....
  12. ncbi request reprint Effects of methamphetamine dependence and HIV infection on cerebral morphology
    Terry L Jernigan
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 9151B, USA
    Am J Psychiatry 162:1461-72. 2005
    ..The authors examined the separate and combined effects of methamphetamine dependence and HIV infection on brain morphology...
  13. pmc Intraindividual variability in HIV infection: evidence for greater neurocognitive dispersion in older HIV seropositive adults
    Erin E Morgan
    Department of Psychiatry, University of California, San Diego, CA 92103, USA
    Neuropsychology 25:645-54. 2011
    ..To our knowledge, no studies have yet examined dispersion in an aging HIV-infected sample...
  14. pmc Is prospective memory a dissociable cognitive function in HIV infection?
    Saurabh Gupta
    Department of Psychiatry, University of California, San Diego, CA 92103, USA
    J Clin Exp Neuropsychol 32:898-908. 2010
    ..The results of this study lend further evidence to the dissociability of ProM in HIV infection, are consistent with prior studies in healthy adults, and contribute to a growing literature on the construct validity of ProM in HIV disease...
  15. pmc CD4 nadir is a predictor of HIV neurocognitive impairment in the era of combination antiretroviral therapy
    Ronald J Ellis
    University of California, San Diego, USA
    AIDS 25:1747-51. 2011
    ..The present study evaluated the probability of neuropsychological impairment (NPI) and HAND as a function of CD4 nadir in an HIV-positive cohort...
  16. pmc Neurobehavioral effects of human immunodeficiency virus infection among former plasma donors in rural China
    Robert K Heaton
    HIV Neurobehavioral Research Center HNRC, Department of Psychiatry, University of California at San Diego, San Diego, California 92093 0603, USA
    J Neurovirol 14:536-49. 2008
    ..These findings indicate that HAND is likely to be an important feature of HIV infection in developing countries, underscoring the need for international efforts to develop CNS-relevant treatments...
  17. pmc Spontaneous strategy use protects against visual working memory deficits in older adults infected with HIV
    Steven Paul Woods
    Department of Psychiatry, University of California San Diego, La Jolla, USA
    Arch Clin Neuropsychol 25:724-33. 2010
    ....
  18. pmc Prospective memory deficits are associated with unemployment in persons living with HIV infection
    Steven Paul Woods
    Department of Psychiatry, University of California, San Diego, USA
    Rehabil Psychol 56:77-84. 2011
    ..To determine whether deficits in prospective memory (i.e., "remembering to remember") confer an increased risk of unemployment in individuals living with chronic HIV infection...
  19. ncbi request reprint Genetics of brain structure: contributions from the Vietnam Era Twin Study of Aging
    William S Kremen
    Department of Psychiatry, University of California, San Diego, La Jolla, California Twin Research Laboratory, Center for Behavioral Genomics, University of California, San Diego, La Jolla, California Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System, La Jolla, California
    Am J Med Genet B Neuropsychiatr Genet 162:751-61. 2013
    ..Examples supporting the validity of these conclusions are provided...
  20. pmc Higher education is not associated with greater cortical thickness in brain areas related to literacy or intelligence in normal aging or mild cognitive impairment
    Jagan A Pillai
    Department of Neurology, VA San Diego Medical Center, San Diego, CA, USA
    J Clin Exp Neuropsychol 34:925-35. 2012
    ..Connectivity and synaptic efficiency or other lifestyle factors may more directly reflect cognitive reserve...
  21. pmc A comparison of heritability maps of cortical surface area and thickness and the influence of adjustment for whole brain measures: a magnetic resonance imaging twin study
    Lisa T Eyler
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Twin Res Hum Genet 15:304-14. 2012
    ..Implications regarding brain phenotypes for future genetic association studies are discussed...
  22. pmc Genetic and environmental influences of white and gray matter signal contrast: a new phenotype for imaging genetics?
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuroimage 60:1686-95. 2012
    ..The lack of significant genetic correlations with cortical thickness suggests that this measure potentially represents a unique source of genetic variance, one that has yet to be explored by the field of imaging genetics...
  23. pmc Demographically corrected norms for African Americans and Caucasians on the Hopkins Verbal Learning Test-Revised, Brief Visuospatial Memory Test-Revised, Stroop Color and Word Test, and Wisconsin Card Sorting Test 64-Card Version
    Marc A Norman
    Department of Psychiatry, University of California, San Diego, CA, USA
    J Clin Exp Neuropsychol 33:793-804. 2011
    ..Findings support the need to consider extended demographic contributions to neuropsychological test performance in clinical and research settings...
  24. pmc Brain substrates of learning and retention in mild cognitive impairment diagnosis and progression to Alzheimer's disease
    Yu Ling Chang
    Department of Psychiatry, University of California, San Diego, 8950 Villa La Jolla Drive Suite C101, La Jolla, CA 92037, USA
    Neuropsychologia 48:1237-47. 2010
    ..Overall, our results highlight the importance of including learning measures in addition to retention measures when making a diagnosis of MCI and for predicting clinical outcome...
  25. pmc Misremembering future intentions in methamphetamine-dependent individuals
    Jennifer E Iudicello
    Joint Doctoral Program in Clinical Psychology, San Diego State University and University of California, San Diego, CA, USA
    Clin Neuropsychol 25:269-86. 2011
    ..Findings suggest that individuals with MA dependence experience difficulty in the strategic components involved in the retrieval of future intentions and are discussed with regard to their implications for everyday functioning...
  26. pmc HIV-associated prospective memory impairment in the laboratory predicts failures on a semi-naturalistic measure of health care compliance
    Jennifer B Zogg
    Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Clin Neuropsychol 24:945-62. 2010
    ..g., depression). Results support the hypothesis that ProM plays a unique role in compliance with health care instructions for HIV disease management and may inform interventions designed to improve treatment outcomes...
  27. pmc Genetic influences on hippocampal volume differ as a function of testosterone level in middle-aged men
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuroimage 59:1123-31. 2012
    ..To the best of our knowledge, this is the first study to demonstrate that the heritability of a brain structure in adults may be modified by an endogenous biological factor...
  28. pmc Hierarchical genetic organization of human cortical surface area
    Chi Hua Chen
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Science 335:1634-6. 2012
    ..We also found that the results were consistent with human-specific regions being subdivisions of previously described, genetically based lobar regionalization patterns...
  29. pmc Heritability of brain ventricle volume: converging evidence from inconsistent results
    William S Kremen
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neurobiol Aging 33:1-8. 2012
    ..These conclusions have implications for the basic understanding of the genetic and environmental underpinnings of normative and pathological brain aging...
  30. pmc Cytochrome P450-2D6 extensive metabolizers are more vulnerable to methamphetamine-associated neurocognitive impairment: preliminary findings
    Mariana Cherner
    Department of Psychiatry, University of California San Diego, La Jolla, California 92093 0847, USA
    J Int Neuropsychol Soc 16:890-901. 2010
    ..This preliminary study is the first to suggest that efficient meth metabolism is associated with worse neurocognitive outcomes in humans, and implicates the products of oxidative metabolism of meth as a possible source of brain injury...
  31. pmc Neuroimaging enrichment strategy for secondary prevention trials in Alzheimer disease
    Linda K McEvoy
    Department of Radiology, University of California, San Diego, La Jolla, CA 92093 0841, USA
    Alzheimer Dis Assoc Disord 24:269-77. 2010
    ..Failure to take into account normal age-related changes risks under-powering trials designed to test disease-modifying properties of potential treatments...
  32. pmc Cognitive reserve moderates the association between hippocampal volume and episodic memory in middle age
    Eero Vuoksimaa
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Neuropsychologia 51:1124-31. 2013
    ..e., lower levels of cognitive reserve. Our results provide support for the hypothesis that cognitive reserve moderates the relationship between brain structure and cognition in middle age, well before the onset of dementia...
  33. pmc A technique for the deidentification of structural brain MR images
    Amanda Bischoff-Grethe
    Laboratory of Cognitive Imaging, Department of Psychiatry, University of California, San Diego, La Jolla, USA
    Hum Brain Mapp 28:892-903. 2007
    ..Analyses support this algorithm as a viable method to allow data sharing with minimal data alteration within large-scale multisite projects...
  34. pmc Prospective memory in HIV infection: is "remembering to remember" a unique predictor of self-reported medication management?
    Steven Paul Woods
    Department of Psychiatry, HIV Neurobehavioral Research Center, University of California, San Diego, School of Medicine, La Jolla, CA 92093, USA
    Arch Clin Neuropsychol 23:257-70. 2008
    ..The potential benefits of individualized remediation strategies that are informed by conceptual models of ProM and specifically target medication adherence warrant further exploration...
  35. pmc A neuropsychological investigation of multitasking in HIV infection: implications for everyday functioning
    J Cobb Scott
    San Diego State University and University of California, San Diego, CA, USA
    Neuropsychology 25:511-9. 2011
    ..The aim of this study was to assess the predictive and ecological validity of a novel multitasking measure in HIV infection...
  36. pmc Cognitive mechanisms of switching in HIV-associated category fluency deficits
    Jennifer E Iudicello
    Joint Doctoral Program in Clinical Psychology, San Diego State University, San Diego, CA 92103, USA
    J Clin Exp Neuropsychol 30:797-804. 2008
    ..g., mental flexibility), perhaps reflecting underlying neuropathology within prefrontostriatal networks...
  37. pmc Normative data and validation of a regression based summary score for assessing meaningful neuropsychological change
    Lucette A Cysique
    Department of Psychiatry, HIV Neurobehavioral Research Center, University of California at San Diego, San Diego, CA, USA
    J Clin Exp Neuropsychol 33:505-22. 2011
    ..Correction for practice effects based on normative data improved the consistency of NP impairment classification in a clinically stable longitudinal cohort after baseline...
  38. pmc Relative capability of MR imaging and FDG PET to depict changes associated with prodromal and early Alzheimer disease
    David S Karow
    Department of Radiology, University of California, San Diego, La Jolla, CA 92093, USA
    Radiology 256:932-42. 2010
    ..To quantify the effect sizes of regional metabolic and morphometric measures in patients with preclinical and mild Alzheimer disease (AD) to aid in the identification of noninvasive biomarkers for the early detection of AD...
  39. pmc Level of executive function influences verbal memory in amnestic mild cognitive impairment and predicts prefrontal and posterior cingulate thickness
    Yu Ling Chang
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92037, USA
    Cereb Cortex 20:1305-13. 2010
    ..Overall, these results demonstrate the importance of evaluating executive function in individuals with MCI to predict involvement of brain areas beyond the mesial temporal lobe...
  40. pmc Genetic and environmental influences on the size of specific brain regions in midlife: the VETSA MRI study
    William S Kremen
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive MC 0738, La Jolla, CA 92093, USA
    Neuroimage 49:1213-23. 2010
    ..Longitudinal analysis will be needed to determine whether the degree of genetic and environmental influences changes for different ROIs from midlife to later life...
  41. pmc Impairments in fine-motor coordination and speed of information processing predict declines in everyday functioning in hepatitis C infection
    Ofilio Vigil
    Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla, CA 92103, USA
    J Clin Exp Neuropsychol 30:805-15. 2008
    ....
  42. pmc Functional interactions of HIV-infection and methamphetamine dependence during motor programming
    Sarah L Archibald
    Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA
    Psychiatry Res 202:46-52. 2012
    ..Thus, HIV and METH dependence, perhaps through their effects on dopaminergic systems, may have opposing functional effects on neural circuits involved in motor programming...
  43. pmc Genetic influences on cortical regionalization in the human brain
    Chi Hua Chen
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
    Neuron 72:537-44. 2011
    ..Broad similarities in genetic patterning between rodents and humans might suggest a conservation of cortical patterning mechanisms, whereas dissimilarities might reflect the functionalities most essential to each species...
  44. pmc Genetic and environmental contributions to regional cortical surface area in humans: a magnetic resonance imaging twin study
    Lisa T Eyler
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Cereb Cortex 21:2313-21. 2011
    ....
  45. pmc Genetic patterns of correlation among subcortical volumes in humans: results from a magnetic resonance imaging twin study
    Lisa T Eyler
    Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
    Hum Brain Mapp 32:641-53. 2011
    ....
  46. ncbi request reprint Correlation of in vivo neuroimaging abnormalities with postmortem human immunodeficiency virus encephalitis and dendritic loss
    Sarah L Archibald
    Department of Psychiatry, University of California, San Diego, and Veterans Affairs San Diego Healthcare System, La Jolla, 92093, USA
    Arch Neurol 61:369-76. 2004
    ..Although previous studies have linked brain viral levels to these alterations, other neuropathological mechanisms might also contribute to them...
  47. pmc Psychiatric context of human immunodeficiency virus infection among former plasma donors in rural China
    J Hampton Atkinson
    HIV Neurobehavioral Research Center, University of California, San Diego, 220 Dickinson St, San Diego, CA 92103, USA
    J Affect Disord 130:421-8. 2011
    ..Little is known of the psychiatric and substance use disorder characteristics of this population, or their impact on everyday function, employment, and life quality...
  48. pmc Methamphetamine use parameters do not predict neuropsychological impairment in currently abstinent dependent adults
    Mariana Cherner
    Department of Psychiatry, University of California San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093 0847, USA
    Drug Alcohol Depend 106:154-63. 2010
    ..The apparent lack of correspondence between substance use parameters and cognitive impairment suggests the need for further study of individual differences in vulnerability to the neurotoxic effects of methamphetamine...
  49. pmc Implications of hepatitis C virus infection for behavioral symptoms and activities of daily living
    Carolina Posada
    San Diego State University University of California, San Diego Joint Doctoral Program in Clinical Psychology, San Diego, CA, USA
    J Clin Exp Neuropsychol 32:637-44. 2010
    ..These results show that a subset of HCV-infected individuals report clinically elevated behavioral symptoms. Clinical implications for the assessment and management of elevated behavioral symptoms in HCV are discussed...
  50. ncbi request reprint Left hippocampal volume loss in Alzheimer's disease is reflected in performance on odor identification: a structural MRI study
    Claire Murphy
    UCSD Joint Doctoral Program, San Diego State University, San Diego, California 92120 4913, USA
    J Int Neuropsychol Soc 9:459-71. 2003
    ..These results support the potential clinical utility of inclusion of odor identification tests in diagnostic batteries for detecting AD...
  51. pmc Negative mood and sexual behavior among non-monogamous men who have sex with men in the context of methamphetamine and HIV
    C A Bousman
    University of California San Diego, HIV Neurobehavioral Research Center, Department of Psychiatry, La Jolla, California 92103, USA
    J Affect Disord 119:84-91. 2009
    ..This study examined the contextual influence of METH, HIV-infection and their combination on mood states and sexual behavior...
  52. pmc Distinct genetic influences on cortical surface area and cortical thickness
    Matthew S Panizzon
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Cereb Cortex 19:2728-35. 2009
    ..We conclude that using volume in a genetically informative study, or as an endophenotype for a disorder, may confound the underlying genetic architecture of brain structure...
  53. ncbi request reprint Conceptual and Data-based Investigation of Genetic Influences and Brain Asymmetry: A Twin Study of Multiple Structural Phenotypes
    Lisa T Eyler
    University of California, San Diego
    J Cogn Neurosci 26:1100-17. 2014
    ..Despite varying interpretations of existing data, we view the present results as consistent with previous findings. ..
  54. pmc Genetic topography of brain morphology
    Chi Hua Chen
    Departments of Psychiatry, Cognitive Science, Radiology, and Neurosciences, Center for Behavioral Genomics, and Institute of Genomic Medicine, University of California, San Diego, La Jolla, CA 92093
    Proc Natl Acad Sci U S A 110:17089-94. 2013
    ..Our findings highlight the complexity of genetic influences on cortical morphology and provide a glimpse into emerging principles of genetic organization of the cortex. ..
  55. ncbi request reprint Progressive impairment on neuropsychological tasks in a longitudinal study of preclinical Alzheimer's disease
    Laura Mickes
    Department of Psychology, University of California, San Diego, CA 92093 0109, USA
    Neuropsychology 21:696-705. 2007
    ....
  56. pmc Effects of traumatic brain injury on cognitive functioning and cerebral metabolites in HIV-infected individuals
    Kenny Lin
    University of California San Diego, San Diego, CA 92093, USA
    J Clin Exp Neuropsychol 33:326-34. 2011
    ..One clinical implication is that HIV patients with TBI history may need to be monitored more closely for increased risk of HIV-associated neurocognitive disorder signs or symptoms...
  57. pmc Alzheimer disease: quantitative structural neuroimaging for detection and prediction of clinical and structural changes in mild cognitive impairment
    Linda K McEvoy
    Department of Radiology, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0841, USA
    Radiology 251:195-205. 2009
    ....
  58. pmc Cognitive phenotypes, brain morphometry and the detection of cognitive decline in preclinical AD
    Mark W Jacobson
    Veterans Affairs San Diego Healthcare System, San Diego, CA 92151, USA
    Behav Neurol 21:29-37. 2009
    ..We review several approaches to defining cognitive subgroups, and we consider the possibility that cognitive asymmetry might provide one means of identifying both functional and structural changes associated with aging and dementia...
  59. pmc Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis
    Linda K McEvoy
    Department of Radiology, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093, USA
    Radiology 259:834-43. 2011
    ..To assess whether single-time-point and longitudinal volumetric magnetic resonance (MR) imaging measures provide predictive prognostic information in patients with amnestic mild cognitive impairment (MCI)...
  60. pmc HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors
    Robert K Heaton
    University of California, San Diego, CA, USA
    J Neurovirol 17:3-16. 2011
    ..Clinical trials targeting HAND prevention should specifically examine timing of ART initiation...
  61. ncbi request reprint Salivary cortisol and prefrontal cortical thickness in middle-aged men: A twin study
    William S Kremen
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neuroimage 53:1093-102. 2010
    ..Longitudinal assessments are underway to elucidate the direction of the associations and the genetic underpinnings of longitudinal phenotypes for changes in cortisol and brain morphology...
  62. pmc Neurocognitive functioning in acute or early HIV infection
    David J Moore
    Department of Psychiatry, University of California, San Diego UCSD, San Diego, CA, USA
    J Neurovirol 17:50-7. 2011
    ..Although a significant monotonic trend existed and patterns of the data suggest the AEH individuals may fall intermediate to HIV- and chronic participants, we were not able to statistically confirm this hypothesis...
  63. pmc Federated web-accessible clinical data management within an extensible neuroimaging database
    I Burak Ozyurt
    Department of Psychiatry, University of California at San Diego, San Diego, CA, USA
    Neuroinformatics 8:231-49. 2010
    ..The system along with its documentation is open-source and available from the Neuroimaging Informatics Tools and Resource Clearinghouse (NITRC) site...
  64. pmc Subregional neuroanatomical change as a biomarker for Alzheimer's disease
    Dominic Holland
    Department of Neurosciences, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 106:20954-9. 2009
    ..The findings indicate that regional temporal lobe cortical changes would have great utility as outcome measures in clinical trials and may also have utility in clinical practice for aiding early diagnosis of neurodegenerative disease...
  65. ncbi request reprint The bilingual effect on Boston Naming Test performance
    Tamar H Gollan
    University of California San Diego, Department of Psychiatry, California 92093 0949, USA
    J Int Neuropsychol Soc 13:197-208. 2007
    ..Bilinguals' ability to name pictures reflects their experience with word forms in both languages...
  66. pmc Variable patterns of neuropsychological performance in HIV-1 infection
    S Dawes
    Department of Psychiatry, HIV Neurobehavioral Research Center, University of California San Diego, San Diego, CA 92093 0603, USA
    J Clin Exp Neuropsychol 30:613-26. 2008
    ..Thus, there does not appear to be a single, prototypical pattern of neuropsychological impairment associated with HIV infection for this battery of representative neuropsychological tests...
  67. pmc Cortical thickness is influenced by regionally specific genetic factors
    Lars M Rimol
    Department of Radiology, University of California, San Diego, La Jolla, California 92093 0738, USA
    Biol Psychiatry 67:493-9. 2010
    ..Yet, little is known about the patterning of those genetic influences, i.e., whether the same genes influence structure throughout the brain or whether there are regionally specific sets of genes...
  68. pmc Relationship between regional atrophy rates and cognitive decline in mild cognitive impairment
    Carrie R McDonald
    Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA
    Neurobiol Aging 33:242-53. 2012
    ..MRI measures of regional atrophy can provide valuable information for understanding the neural basis of cognitive impairment in MCI...
  69. pmc Does amygdalar perfusion correlate with antidepressant response to partial sleep deprivation in major depression?
    Camellia P Clark
    Department of Psychiatry 9151B, San Diego V A Medical Center, University of California at San Diego, La Jolla, CA 92093, USA
    Psychiatry Res 146:43-51. 2006
    ....
  70. pmc Psychometric characteristics of the memory for intentions screening test
    Steven Paul Woods
    Department of Psychiatry, University of California, San Diego, CA, USA
    Clin Neuropsychol 22:864-78. 2008
    ..Recommendations are provided regarding future research to enhance the clinical usefulness of the MIST...
  71. ncbi request reprint Bilingualism affects picture naming but not picture classification
    Tamar H Gollan
    Department of Psychiatry, University of California, San Diego, La Jolla, California 92093 0949, USA
    Mem Cognit 33:1220-34. 2005
    ....
  72. pmc Preliminary evidence of motor impairment among polysubstance 3,4-methylenedioxymethamphetamine users with intact neuropsychological functioning
    Chad A Bousman
    Department of Psychiatry, University of California San Diego, La Jolla, California 92093, USA
    J Int Neuropsychol Soc 16:1047-55. 2010
    ..However, replication of this finding in a larger sample is warranted...
  73. pmc Increased accumulation of intraneuronal amyloid beta in HIV-infected patients
    Cristian L Achim
    Department of Psychiatry, University of California, San Diego, CA 92093 0624, USA
    J Neuroimmune Pharmacol 4:190-9. 2009
    ..These findings suggest that long-term survival with HIV might interfere with clearance of proteins such as Abeta and worsen neuronal damage and cognitive impairment in this population...
  74. pmc Quantitative evaluation of automated skull-stripping methods applied to contemporary and legacy images: effects of diagnosis, bias correction, and slice location
    Christine Fennema-Notestine
    Laboratory of Cognitive Imaging, Department of Psychiatry, University of California, San Diego, and Veterans Affairs San Diego Healthcare System, San Diego, La Jolla, California 92093, USA
    Hum Brain Mapp 27:99-113. 2006
    ..The results of this study may direct users towards a method appropriate to their T1-weighted datasets and improve the efficiency of processing for large, multisite neuroimaging studies...
  75. pmc Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative
    Owen Carmichael
    Department of Neurology, School of Medicine, University of California, Davis, CA, USA
    Arch Neurol 67:1370-8. 2010
    ....
  76. pmc Incidence and nature of cognitive decline over 1 year among HIV-infected former plasma donors in China
    Lucette A Cysique
    Department of Psychiatry, HIV Neurobehavioral Research Center HNRC, University of California at San Diego, La Jolla, CA 92093 0603, USA
    AIDS 24:983-90. 2010
    ..To quantify and characterize the nature of cognitive change over 1 year in a cohort of HIV-positive former plasma donors in rural China...
  77. pmc Efavirenz concentrations in CSF exceed IC50 for wild-type HIV
    Brookie M Best
    University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA, USA
    J Antimicrob Chemother 66:354-7. 2011
    ..This study's objective was to determine penetration of a commonly prescribed antiretroviral drug, efavirenz, into CSF...
  78. ncbi request reprint White matter mapping is needed
    T L Jernigan
    University of California, San Diego, La Jolla, CA 92093 0949, USA
    Neurobiol Aging 25:37-9. 2004
  79. ncbi request reprint More "mapping" in brain mapping: statistical comparison of effects
    Terry L Jernigan
    Veterans Affairs San Diego Healthcare System, San Diego, California 92093, USA
    Hum Brain Mapp 19:90-5. 2003
    ..Evidence for sufficient effect size difference between the effects in structures of interest should be a prerequisite to the interpretation of spatial patterns of activation...
  80. pmc The NIFSTD and BIRNLex vocabularies: building comprehensive ontologies for neuroscience
    William J Bug
    Center for Research in Biological Systems, University of California, San Diego, San Diego, CA 92093 0446, USA
    Neuroinformatics 6:175-94. 2008
    ..We report here on the structure of the NIFSTD, and its predecessor BIRNLex, the principles followed in its construction and provide examples of its use within NIF...
  81. pmc Differential expression of immunophilins FKBP51 and FKBP52 in the frontal cortex of HIV-infected patients with major depressive disorder
    Erick T Tatro
    Department of Psychiatry 0603, University of California at San Diego, La Jolla, San Diego, CA 92093 0603, USA
    J Neuroimmune Pharmacol 4:218-26. 2009
    ..Instead, an increase in FKBP51 at both the transcript (FKBP5) and protein level correlated with MDD. Increased FKBP4 expression of correlated to HIV(+)MDD but not to HIV without MDD...
  82. pmc Pleocytosis is associated with disruption of HIV compartmentalization between blood and cerebral spinal fluid viral populations
    Davey M Smith
    University of California San Diego, La Jolla, 92093, USA
    Virology 385:204-8. 2009
    ....
  83. ncbi request reprint Brain morphometry in female victims of intimate partner violence with and without posttraumatic stress disorder
    Christine Fennema-Notestine
    Veterans Affairs San Diego Healthcare System, San Diego, USA
    Biol Psychiatry 52:1089-101. 2002
    ..To examine neuroanatomical morphometry in adult female victims of intimate partner violence with and without posttraumatic stress disorder...
  84. doi request reprint Enabling public data sharing: encouraging scientific discovery and education
    Christine Fennema-Notestine
    Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
    Methods Mol Biol 569:25-32. 2009
    ....