Research Topics
Species | Sandy FengSummaryAffiliation: University of California Country: USA Publications
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Publications
Tumors and transplantation: The 2003 Third Annual ASTS State-of-the-Art Winter SymposiumSandy Feng
Division of Transplantation, Department of Surgery, University of California San Francisco, USA
Am J Transplant 3:1481-7. 2003- Trends over a decade of pediatric liver transplantation in the United StatesSandy Feng
Department of Surgery, University of California San Francisco, San Francisco, CA 94143 0780, USA
Liver Transpl 12:578-84. 2006..In conclusion, the sobering reality that mortality on the waiting list remains highest for the youngest pediatric liver candidates frames our challenge for the next decade... - Surgical challenges in transplantation: the Fourth Annual American Society of Transplant Surgeons' State-of-the-Art Winter SymposiumSandy Feng
Department of Surgery, Division of Transplantation, University of California San Francisco, USA
Am J Transplant 5:428-35. 2005 - Developments in clinical islet, liver thoracic, kidney and pancreas transplantation in the last 5 yearsS Feng
Department of Surgery, Division of Transplantation, University of California, San Francisco, USA
Am J Transplant 6:1759-67. 2006.... - Selecting livers for transplantation: can beggars be choosers?Sandy Feng
University of California San Francisco, San Francisco, 94143, USA
Nat Clin Pract Gastroenterol Hepatol 2:496-7. 2005 - Characteristics associated with liver graft failure: the concept of a donor risk indexS Feng
Department of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, California, USA
Am J Transplant 6:783-90. 2006..Quantitative assessment of the risk of donor liver graft failure using a donor risk index is useful to inform the process of organ acceptance... - Organ donors with positive viral serology or malignancy: risk of disease transmission by transplantationSandy Feng
Department of Surgery, Division of Transplantation, University of California, San Francisco, San Francisco, CA 94143-0780, USA
Transplantation 74:1657-63. 2002 - Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: an intention-to-treat analysisFrancis Y Yao
Department of Medicine, University of California, San Francisco, San Francisco, CA, USA
Hepatology 48:819-27. 2008..CONCLUSION: Successful down-staging of HCC can be achieved in the majority of carefully selected patients and is associated with excellent posttransplantation outcome... - Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomyShigeki Sekine
Diabetes Center, Department of Medicine, Division of Transplantation, University of California San Francisco, San Francisco, CA 94143, USA
Hepatology 45:361-8. 2007.... - Comparison of outcomes after delayed graft function: sirolimus-based versus other calcineurin-inhibitor sparing induction immunosuppression regimensRyan A McTaggart
Department of Surgery, Division of Transplantation, University of California San Francisco, 94143-0780, USA
Transplantation 78:475-80. 2004..All three CNI-sparing induction IS regimens resulted in comparable patient survival, graft survival, and graft function... - Increased rejection in living unrelated versus living related kidney transplants does not affect short-term function and survivalT Florian Fuller
Department of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, CA 94143, USA
Transplantation 78:1030-5. 2004..In high-risk patients receiving living unrelated renal transplants, consideration should be given to intensify initial immunosuppression to prevent early rejection episodes... - BKV in simultaneous pancreas-kidney transplant recipients: a leading cause of renal graft loss in first 2 years post-transplantGerald S Lipshutz
University of California, Los Angeles, Department of Surgery, Los Angeles, CA, USA
Am J Transplant 5:366-73. 2005..The pancreas, however, is spared from evidence of infection, and no pancreatic rejection occurred when immunosuppression was decreased... - Expanded criteria donor kidney allocation: marked decrease in cold ischemia and delayed graft function at a single centerJonathan T Carter
Division of Transplant Surgery, University of California-San Francisco, San Francisco, CA, USA
Am J Transplant 5:2745-53. 2005..0033) and cold ischemia time (OR 1.24/h; p = 0.0036). We conclude the ECD designation provides a description of kidney quality that may obviate biopsy. ECD allocation decreased cold ischemia time and DGF, which may improve graft survival... - Hepatitis C etiology of liver disease is strongly associated with early acute rejection following liver transplantationRyan A McTaggart
Department of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, CA 94143-0780, USA
Liver Transpl 10:975-85. 2004..Alternatively, the association of HCV and EAR may result from an increased frequency of allograft biopsy and may be further exacerbated by inability to accurately diagnose EAR in the setting of recurrent HCV... - Complete immunosuppression withdrawal and subsequent allograft function among pediatric recipients of parental living donor liver transplantsSandy Feng
Division of Transplantation, Department of Surgery, University of California, San Francisco, CA 94143, USA
JAMA 307:283-93. 2012..Although life-saving, liver transplantation burdens children with lifelong immunosuppression and substantial potential for morbidity and mortality... - Long-term histological effects of preemptive antiviral therapy in liver transplant recipients with hepatitis C virus infectionAlexander Kuo
Division of Gastroenterology, University of California, San Diego, CA, USA
Liver Transpl 14:1491-7. 2008..004). We conclude that preemptive antiviral therapy in virologic nonresponders delays the time to subsequent HCV treatment and may confer a reduced risk of fibrosis progression. Further study of preemptive antiviral therapy is warranted... - Optimizing living donor kidney graft function by donor-recipient pair selectionTodd V Brennan
Department of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, CA 94143-0780, USA
Transplantation 82:651-6. 2006..CONCLUSIONS: In the setting of multiple potential living kidney donors, this quantitative tool may facilitate the choice of the optimal donor... - Allocation policy for hepatocellular carcinoma in the MELD era: room for improvement?Kayvan Roayaie
Department of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, CA 94143 0780, USA
Liver Transpl 13:S36-43. 2007.... - Long-term management of immunosuppression after pediatric liver transplantation: is minimization or withdrawal desirable or possible or both?Sandy Feng
University of California San Francisco, San Francisco, CA 94143 0780, USA
Curr Opin Organ Transplant 13:506-12. 2008..The aim is to review available data regarding the risks and benefits of indefinite immunosuppression against attempted immunosuppression withdrawal for children who have undergone liver transplantation... - Excellent short-term results with steroid-free maintenance immunosuppression in low-risk simultaneous pancreas-kidney transplantationChris E Freise
Division of Transplantation, University of California San Francisco, 94143, USA
Arch Surg 138:1121-5; discussion 1125-6. 2003..Steroid avoidance is possible in simultaneous pancreas-kidney transplantation with the use of newer immunosuppressive agents and induction therapy... - Early graft function after living donor kidney transplantation predicts rejection but not outcomesTodd V Brennan
Department of Surgery, Division of Transplantation, University of California-San Francisco, San Francisco, CA, USA
Am J Transplant 4:971-9. 2004..We suggest that immunosuppression should be intensified in the poor EGF setting to maximize LDKT longevity, as AR does impair functional graft survival... - Kidney transplant performed after liver transplant: a single center experienceMatthew H Levine
Division of Transplant Surgery, Department of Surgery, University of Pennsylvania, Philadelphia, PA 19104, USA
Clin Transplant 25:915-20. 2011..Death censored graft survival was statistically lower in the KALT group but this largely accrued in the first three yr after transplant and was nearly equivalent by 10 yr... - Linking the US transplant registry to administrative claims data: expanding the potential of transplant researchAmanda S Gilmore
Health Benchmarks, Inc, Woodland Hills, California, USA
Med Care 45:529-36. 2007..This study linked OPTN and private payer claims data to assess the relationship between data elements common to both sources... - A prospective study on downstaging of hepatocellular carcinoma prior to liver transplantationFrancis Y Yao
Department of Medicine, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143 0538, USA
Liver Transpl 11:1505-14. 2005..3 and 81.8% at 1 and 2 yr, respectively. In conclusion, successful tumor downstaging can be achieved in the majority of carefully selected patients, but longer follow-up is needed to further access the risk of HCC recurrence after OLT... - Management of the liver transplant patientBruce Gelb
Division of Transplantation, Department of Surgery, UCSF Medical Center, San Francisco, CA, USA
Expert Rev Gastroenterol Hepatol 3:631-47. 2009..Finally, the substantial challenges of recurrent disease and long-term medical comorbidities are addressed as these are clearly the primary issues that threaten the longevity and wellbeing of the liver transplant recipient... - Magnetic resonance imaging of hepatocellular carcinoma mimicking focal nodular hyperplasia: a potential pitfall in patients with cirrhosis?Olga Rafaelian
Department of Radiology, University of California San Francisco, San Francisco, CA 94143 0628, USA
J Comput Assist Tomogr 30:796-9. 2006..Recognition that hepatocellular carcinoma may mimic focal nodular hyperplasia in patients with cirrhosis may prevent misdiagnosis and allow for earlier intervention... - Experience with steroid-free maintenance immunosuppression in simultaneous pancreas-kidney transplantationC E Freise
Transplant Division, Department of Surgery, University of California, San Francisco, 94143, USA
Transplant Proc 36:1067-8. 2004..We undertook a retrospective consecutive case review of patients treated at a university tertiary referral center... - Optimizing the use of cyclosporine (Neoral) for recipients of living donor kidneysF Vincenti
Kidney Transplant Service, University of California San Francisco, San Francisco, CA 94143-0780, USA
Transplant Proc 36:50S-53S. 2004 - Death from donor-transmitted malignancy despite emergency liver retransplantationGerald S Lipshutz
Division of Transplantation, Department of Surgery, University of California, San Francisco, CA 94143, USA
Liver Transpl 9:1102-7. 2003..This case of donor-transmitted malignancy underscores the need for vigilance by the procuring surgeon in identifying potential malignancy during organ retrieval and use of a full autopsy on selected donors after organ procurement... - Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in miceShigeki Sekine
Department of Medicine, Diabetes Center, University of California San Francisco, San Francisco, CA 94143 0573, USA
Hepatology 43:817-25. 2006..In conclusion, in addition to regulating hepatocyte proliferation, beta-catenin may also control multiple aspects of normal liver function... - Targeted gene therapy with CD40Ig to induce long-term acceptance of liver allograftsGeorge J Chang
Division of Transplantation Surgery, Department of Surgery, University of California, San Francisco School of Medicine, 94143, USA
Surgery 132:149-56. 2002.... - Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantationRyan A McTaggart
Department of Surgery, Division of Transplantation, University of California-San Francisco, San Francisco, CA, USA
Am J Transplant 3:416-23. 2003..034). Sirolimus retained its profound negative association with time to graft function in all multivariate models. Because sirolimus appears to prolong DGF, it may not be the optimal immunosuppressive choice in the DGF setting... - Living donor kidney transplant recipients and clinical trials: participation profiles and impact on post-transplant careT V Brennan
Department of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, California, USA
Am J Transplant 6:2429-35. 2006..Overall graft and patient survival were comparable. We conclude that clinical trial participants were disproportionately male, had increased intensity of post-transplant care but comparable outcomes to nonparticipants... - Developmental context determines latency of MYC-induced tumorigenesisShelly Beer
Division of Oncology, Department of Medicine, Stanford University, Stanford, California, USA
PLoS Biol 2:e332. 2004..Adult somatic cells have evolved mechanisms to prevent individual oncogenes from initiating cellular growth, DNA replication, and mitotic cellular division alone, thereby preventing any single genetic event from inducing tumorigenesis... - Organ donors with malignant gliomas: an updateFederic P Collignon
Department of Surgery, Division of Neurosurgery, Memorial Sloane Kettering Cancer Center, 1275 York Avenue, New York, NY, USA
Am J Transplant 4:15-21. 2004..We will then present recent knowledge regarding basic glioma biology that speaks to their metastatic potential and suggest rational strategies for the post-transplant management of recipients of organs from donors with glioma... - Diabetes mellitus: a risk factor for delayed graft function after deceased donor kidney transplantationJ Parekh
Department of Surgery, Division of Transplantation, University of California San Francisco, CA, USA
Am J Transplant 10:298-303. 2010..28, 95% CI 1.15-1.43, p < 0.01). It is unknown whether the deleterious impact of recipient diabetes on graft function after renal transplantation results from perioperative hyperglycemia or the chronic sequelae of diabetes... - Polyomavirus-associated nephropathy in simultaneous kidney-pancreas transplant recipients: a single-center experienceG S Lipshutz
Department of Surgery, University of California, San Francisco, 94143, USA
Transplant Proc 36:1097-8. 2004..Retransplantation can be considered based on our limited experience... - Ascites in hepatitis C liver transplant recipients frequently occurs in the absence of advanced fibrosisB Y Lan
Department of Surgery, Division of Transplantation, University of California San Francisco, San Francisco, CA, USA
Am J Transplant 8:366-76. 2008..Two thirds of ascites episodes, however, occurred without significant fibrosis or histopathology... - The Art and Science of Immunosuppression: the Fifth Annual American Society of Transplant Surgeon's State-of-the-Art Winter SymposiumE A Pomfret
Department of Surgery, Division of Liver Transplantation and Hepatobiliary Surgery, Lahey Clinic Medical Center, Burlington, MA, USA
Am J Transplant 6:275-80. 2006..Finally, the available technologies for molecular and genetic diagnostics and the clinical correlation in the post-transplant setting were discussed... - MR arthrography of the glenohumeral joint: a tailored approachC B Chung
Department of Radiology, Musculoskeletal Division, University of California, San Diego, and Veterans Healthcare System, 3350 La Jolla Village Dr, San Diego, CA 92161, USA
AJR Am J Roentgenol 177:217-9. 2001..CONCLUSION: A tailored approach to MR arthrography may be a useful way to isolate expected pathology in the shoulder and limit confounding findings related to the performance of the procedure... - Donor intervention and organ preservation: where is the science and what are the obstacles?S Feng
University of California San Francisco, San Francisco, CA, USA
Am J Transplant 10:1155-62. 2010..Consideration will then be given to the scientific, logistical and ethical obstacles that impede the transformation of laboratory breakthroughs into innovative treatments that simultaneously improve organ quality and supply... - How can we define expanded criteria for liver donors?Robert M Merion
University of Michigan, Ann Arbor, MI, USA
J Hepatol 45:484-8. 2006 - National conference to assess antibody-mediated rejection in solid organ transplantationSteven K Takemoto
Dumont Transplant Program and Immunogenetics Center, UCLA School of Medicine, UCLA, Los Angeles, CA, USA
Am J Transplant 4:1033-41. 2004..Immunologic barriers once considered insurmountable are now consistently overcome to enable more patients to undergo organ transplantation... - In a MELD-based economy, how can we fight off inflation?Scott W Biggins
Liver Transpl 13:2-4. 2007 - An older liver in the hand, or a (possibly) younger liver in the bush?Sandy Feng
Am J Transplant 5:425-7. 2005 - Impact of sirolimus on early graft function after deceased-donor kidney transplantationRyan A McTaggart
Transplantation 79:991; author reply 991-2. 2005 - Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injuryT Florian Fuller
Department of Urology, , Humboldt University Berlin, Berlin, Germany
Transplantation 76:1594-9. 2003..The antiproliferative effect of SRL may translate into impairment of tubular repair and regeneration necessary for recovery after such injury... - Laparoscopic procurement of kidneys with multiple renal arteries is associated with increased ureteral complications in the recipientJonathan T Carter
Division of Transplantation Surgery, University of California - San Francisco, USA
Am J Transplant 5:1312-8. 2005..Given the current excellent results with right-sided donor nephrectomy, kidneys with single arteries should be preferentially procured, irrespective of side... - Management of lymphoceles after renal transplantation: laparoscopic versus open drainageT Florian Fuller
Department of Urology, , Humboldt-University Berlin, Germany
J Urol 169:2022-5. 2003..However, open drainage should be performed in patients with wound complications and in those with a small lymphocele adjacent to vital renal structures... - End stage polycystic kidney disease: indications and timing of native nephrectomy relative to kidney transplantationT Florian Fuller
Department of Urology, Charite University Hospital, Campus Charite Mitte, Schumannstrasse 20 21, 10117 Berlin, Germany
J Urol 174:2284-8. 2005..We evaluated the indications for and outcome of pre-transplant, concomitant and post-transplant native nephrectomy in patients with end stage polycystic kidney disease (PCKD)... - PELD: working well, but only half of the time?John C Magee
Am J Transplant 5:1785-6. 2005 - Report of the Crystal City meeting to maximize the use of organs recovered from the cadaver donorBruce R Rosengard
Harvard Medical School, Massachusetts General Hospital, Boston 02114, USA
Am J Transplant 2:701-11. 2002 - Expanded criteria donors for kidney transplantationRobert A Metzger
TransLife-Florida Hospital Medical Center, Orlando, FL, USA
Am J Transplant 3:114-25. 2003 - Transplantation of islets transduced with CTLA4-Ig and TGFbeta using adenovirus and lentivirus vectorsJustin R Fernandes
Section on Islet Transplantation and Cell Biology, Joslin Diabetes Center, Harvard Medical School, One Joslin Place, Room 535, Boston, MA 02215, USA
Transpl Immunol 13:191-200. 2004....