Research Topics
| A M FendrickSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Value-based insurance design: more health at any priceA Mark Fendrick
Department of Internal Medicine, Center for Value Based Insurance Design, University of Michigan, Ann Arbor, MI, 48109 0429, USA
Health Serv Res 47:404-13. 2012..A wide-ranging approach, planned as early as possible, can lead to the successful translation of health services research to policy...
A review of the benefits and risks of nonsteroidal anti-inflammatory drugs in the management of mild-to-moderate osteoarthritisA Mark Fendrick
BlueSpark Healthcare Communications, 150 Allen Road, Suite 202, Basking Ridge, NJ 07920, USA
Osteopath Med Prim Care 3:1. 2009..This article provides primary care physicians with the information needed to assist them in making more informed decisions in managing patients experiencing mild-to-moderate OA pain...
Value-based insurance design: a "clinically sensitive, fiscally responsible" approach to mitigate the adverse clinical effects of high-deductible consumer-directed health plansA Mark Fendrick
J Gen Intern Med 22:890-1. 2007
A controlled trial of value-based insurance design - The MHealthy: Focus on Diabetes (FOD) trialAlicen Spaulding
Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI, USA
Implement Sci 4:19. 2009..This program has the potential for broad dissemination to other employers and insurers wishing to improve the value of their health care spending...
Emergency department documentation templates: variability in template selection and association with physical examination and test ordering in dizziness presentationsKevin A Kerber
Department of Neurology, University of Michigan Health System, Ann Arbor, MI, USA
BMC Health Serv Res 11:65. 2011..We aimed to describe the selection of templates in ED dizziness presentations and to investigate the association between items on templates and process utilization...
Value-based insurance design: embracing value over cost aloneA Mark Fendrick
Departments of Internal Medicine and Health Management and Policy, Center for Value Based Insurance Design, University of Michigan, 300 North Ingalls Bldg, Rm 7E06, Ann Arbor, MI 48109 0429, USA
Am J Manag Care 15:S277-83. 2009....
Allergen-induced inflammation and the role of immunoglobulin E (IgE)A M Fendrick
University of Michigan Medical Center, Division of General Medicine, Ann Arbor, MI 48109 0429, USA
Am J Ther 8:291-7. 2001..Thus, anti-IgE antibodies represent proof that IgE plays a central role in allergic reactions and that anti-IgE therapy is a potentially effective treatment for allergic disease...
Diagnosis and treatment of upper respiratory tract infections in the primary care settingA M Fendrick
University of Michigan School of Medicine, Ann Arbor, USA
Clin Ther 23:1683-706. 2001....
Applying value-based insurance design to low-value health servicesA Mark Fendrick
Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Health Aff (Millwood) 29:2017-21. 2010....
A benefit-based copay for prescription drugs: patient contribution based on total benefits, not drug acquisition costA M Fendrick
Division of General Internal Medicine, Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, MI, USA
Am J Manag Care 7:861-7. 2001..Implementation of such a system would provide a financial incentive for individuals to prioritize their out-of-pocket drug expenditures based on the value of their medications, not their price...
Helicobacter pylori and NSAID gastropathy: an ambiguous associationA M Fendrick
Division of General Medicine, Consortium for Health Outcomes, Innovation, and Cost Effectiveness Studies, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48109 0429, USA
Curr Rheumatol Rep 3:107-11. 2001..pylori infection and eradication on clinically significant adverse events, a compelling argument can be made for H. pylori testing of chronic NSAID users at increased risk for ulcer disease and eradicating the organism if present...
The role of economic evaluation in the diagnosis and treatment of Helicobacter pylori infectionA M Fendrick
Division of General Medicine, Consortium for Health Outomces, Innovation, and Cost Effectiveness Studies CHOICES, Departments of Internal Medicine and Health Management and Policy, University of Michigan, Ann Arbor, Michigan, USA
Gastroenterol Clin North Am 29:837-51. 2000....
Immediate endoscopy or initial Helicobacter pylori serological testing for suspected peptic ulcer disease: estimating cost-effectiveness using decision analysisA M Fendrick
Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor 48109, USA
Yale J Biol Med 69:187-95. 1996..To compare the clinical and economic effects of a strategy using immediate endoscopy to a non-invasive strategy utilizing a serologic test for Helicobacter pylori infection for individuals with symptoms suggestive of peptic ulcer disease...
"Fiscally responsible, clinically sensitive" cost sharing: contain costs while preserving qualityA Mark Fendrick
Departments of Internal Medicine and Health Management and Policy, University of Michigan, Ann Arbor, Mich, USA. E-mail
Am J Manag Care 13:325-7. 2007
Clinical and economic effects of population-based Helicobacter pylori screening to prevent gastric cancerA M Fendrick
Consortium for Health Outcomes, Innovation, and Cost Effectiveness Studies, University of Michigan School of Medicine, Ann Arbor, USA
Arch Intern Med 159:142-8. 1999..However, the extent to which H. pylori eradication decreases the risk of gastric cancer is unknown, raising the question of whether population-based H. pylori screening should be undertaken...
Clinical and economic impact of a combination Haemophilus influenzae and Hepatitis B vaccine: estimating cost-effectiveness using decision analysisA M Fendrick
Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, USA
Arch Pediatr Adolesc Med 153:126-36. 1999..Although a combined HBV-Haemophilus influenzae type b (Hib) vaccine may improve acceptance of the HBV vaccine, the clinical and economic consequences of this intervention are uncertain...
The economic burden of non-influenza-related viral respiratory tract infection in the United StatesA Mark Fendrick
Division of General Internal Medicine, Department of Internal Medicine, School of Medicine, University of Michigan, 300 N Ingalls Bldg, Room 7E06, Ann Arbor, MI 48109 0376, USA
Arch Intern Med 163:487-94. 2003..Our objectives were to obtain an updated incidence of non-influenza-related VRTI in the United States and to quantify the health care resource use (direct costs) and productivity losses (indirect costs) associated with these infections...
Value-based insurance design: aligning incentives to bridge the divide between quality improvement and cost containmentA Mark Fendrick
Departments of Internal Medicine and Health Management and Policy, Center for Value Based Insurance Design, University of Michigan, 300 N Ingalls Bldg, Rm 7E06, Ann Arbor, MI 48109 0429, USA
Am J Manag Care 12:SP5-SP10. 2006....
Developing an economic rationale for the use of selective COX-2 inhibitors for patients at risk for NSAID gastropathyA Mark Fendrick
Department of Internal Medicine, Health Management and Policy, University of Michigan, Ann Arbor 48109 0429, USA
Cleve Clin J Med 69:SI59-64. 2002..For individuals who are at an increased risk of developing GI complications attributable to NSAIDs, coxibs are clearly a cost-effective treatment option...
Self-selection and use patterns of over-the-counter omeprazole for frequent heartburnA Mark Fendrick
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Clin Gastroenterol Hepatol 2:17-21. 2004..The Food and Drug Administration approval and subsequent launch of over-the-counter (OTC) omeprazole raises the question whether consumers would use OTC omeprazole appropriately in a "real world" setting...
Step-down from multiple- to single-dose proton pump inhibitors (PPIs): a prospective study of patients with heartburn or acid regurgitation completely relieved with PPIsJohn M Inadomi
Department of Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, Michigan, USA
Am J Gastroenterol 98:1940-4. 2003..This intervention can decrease management costs without adversely affecting quality of life...
Noninvasive Helicobacter pylori testing for the "test-and-treat" strategy: a decision analysis to assess the effect of past infection on test choiceW D Chey
Divisions of Gastroenterology, University of Michigan, Ann Arbor, MI, USA
Arch Intern Med 161:2129-32. 2001..Clinical guidelines support a noninvasive Helicobacter pylori "test-and-treat" strategy for individuals with uncomplicated dyspepsia. However, consensus is lacking regarding the preferred noninvasive testing method...
Helicobacter pylori screening for individuals requiring chronic NSAID therapy: a decision analysisJ M Scheiman
Consortium for Health Outcomes, Innovation, and Cost Effectiveness Studies, University of Michigan School of Medicine, Ann Arbor, MI
Aliment Pharmacol Ther 15:63-71. 2001..pylori infection on the incidence of NSAID-related complications and whether H. pylori eradication reduces the rate of adverse events...
Acute exacerbation of chronic bronchitis: disease-specific issues that influence the cost-effectiveness of antimicrobial therapyS Saint
Division of General Medicine, University of Michigan Medical School, 48109 0429, USA
Clin Ther 23:499-512. 2001..Health care payers increasingly expect that the results of evidence-based economic evaluations will guide practitioners in their choice of cost-effective interventions...
Willingness to pay for diagnostic certainty: comparing patients, physicians, and managed care executivesR A Hirth
Department of Health Management and Policy, University of Michigan, Ann Arbor, Mich. 48109-2029, USA
J Gen Intern Med 14:193-5. 1999..Although nearly all patients valued diagnostic certainty, its value was generally small and insufficient to change the cost-effectiveness ranking of treatment alternatives...
Primary-care physicians' perceptions and practices on the management of GERD: results of a national surveyWilliam D Chey
University of Michigan Health System, Ann Arbor, Michigan 49109-0362, USA
Am J Gastroenterol 100:1237-42. 2005..CONCLUSIONS: Our survey has identified a number of areas of controversy and confusion related to the management of GERD. We hope that our findings can assist in the development of educational materials on GERD for PCPs...
The potential clinical and economic benefits of silver alloy urinary catheters in preventing urinary tract infectionS Saint
Division of General Medicine, Department of Internal Medicine, University of Michigan, 3116 Taubman Center, Campus Box 0376, Ann Arbor, MI 48109 0376, USA
Arch Intern Med 160:2670-5. 2000..A recent meta-analysis concluded that silver alloy catheters reduce the incidence of UTI by 3-fold; however, clinicians must decide whether the efficacy of such catheters is worth the extra per unit cost of $5.30...
Primary care physician perceptions of non-steroidal anti-inflammatory drug and aspirin-associated toxicity: results of a national surveyW D Chey
Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA
Aliment Pharmacol Ther 23:655-68. 2006..To assess primary care physician perceptions of non-steroidal anti-inflammatory drug (NSAID) and aspirin-associated toxicity...
Changing perceptions and practices regarding aspirin, nonsteroidal anti-inflammatory drugs, and cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs among US primary care providersN Elnachef
Division of Gastroenterology, University of Michigan, Ann Arbor, MI 48109, USA
Aliment Pharmacol Ther 28:1249-58. 2008..Our understanding of the benefits and risks of aspirin non steroidal anti-inflammatory drugs (NSAIDs), cyclooxygenase-2 (COX-2) selective NSAIDs and gastro-protective agents (GPAs) continues to expand...
Estimating the cost of informal caregiving for elderly patients with cancerJ A Hayman
Department of Radiation Oncology, University of Michigan, Ann Arbor, 48109, USA
J Clin Oncol 19:3219-25. 2001..Although estimates of the associated direct medical costs exist, very little information is available regarding the prevalence, time, and cost associated with informal caregiving for elderly cancer patients...
Potential clinical and economic effects of homocyst(e)ine loweringB K Nallamothu
Division of General Medicine, University of Michigan Medical Center, 3116 Taubman Center, Ann Arbor, MI 48109 0376, USA
Arch Intern Med 160:3406-12. 2000..However, the benefits expected from lowering homocyst(e)ine levels with folic acid and vitamin B(12) supplementation have yet to be demonstrated in clinical trials...
Gastroenterologists utilize the referral for EGD to enhance colon cancer screening more effectively than primary care physiciansS B Menees
Division of Gastroenterology, University of Michigan, Ann Arbor, 48109, USA
Aliment Pharmacol Ther 23:953-62. 2006..We hypothesize that gastroenterologists seize this opportunity more frequently than primary care providers...
The future of health economic modeling: have we gone too far or not far enough?A Mark Fendrick
Department of Internal Medicine and Health Management and Policy, University of Michigan Medical Center, Ann Arbor, MI, USA
Value Health 9:179-80. 2006
Screening and surveillance for Barrett esophagus in high-risk groups: a cost-utility analysisJohn M Inadomi
Veterans Affairs Ann Arbor Health Systems, 2215 Fuller Road, Ann Arbor, MI 48105, USA
Ann Intern Med 138:176-86. 2003..However, subsequent surveillance of patients with Barrett esophagus but no dysplasia, even at 5-year intervals, is an expensive practice...
Cost-effectiveness comparison of therapy for psoriasis with a methotrexate-based regimen versus a rotation regimen of modified cyclosporine and methotrexateCharles N Ellis
Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI, USA
J Am Acad Dermatol 46:242-50. 2002..If even a small utility gain accompanies the complete clearing of psoriasis, such a strategy may be a worthwhile investment of resources comparable to other healthcare interventions...
Suboptimal statin adherence and discontinuation in primary and secondary prevention populationsJeffrey J Ellis
Department of Pharmacy Services, University of Michigan Hospitals and Health Centers, Ann Arbor, Michigan, USA
J Gen Intern Med 19:638-45. 2004..To compare statin nonadherence and discontinuation rates of primary and secondary prevention populations and to identify factors that may affect those suboptimal medication-taking behaviors...
Colorectal cancer screening behavior in women attending screening mammography: longitudinal trends and predictorsRuth C Carlos
VA Center for Practice Management and Outcomes Research, Ann Arbor, Michigan, USA
Womens Health Issues 15:249-57. 2005..0%. Future studies should examine whether delivering CRC screening interventions at a screening mammography visit increase adherence to non-FOBT CRC screening...
Respiratory illness caused by picornavirus infection: a review of clinical outcomesA S Monto
Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA
Clin Ther 23:1615-27. 2001..New treatments should be assessed not only in terms of their ability to produce the desired clinical outcome, but also in terms of their ability to reduce the burden of disease, decrease health care costs, and improve productivity...
Outcomes of initial noninvasive Helicobacter pylori testing in U.S. primary care patients with uninvestigated dyspepsiaU Ladabaum
Department of Internal Medicine, University of Michigan, Ann Arbor, USA
Am J Gastroenterol 96:2051-7. 2001..pylori testing than the cost of endoscopy alone. Seropositive and seronegative patients experienced comparable outcomes after H. pylori testing...
Decomposing pharmaceutical cost growth in different types of health plansM E Chernew
Department of Health Management and Policy, University of Michigan School of Public Health, 109 Observatory Rm M3118, Ann Arbor, MI 48109 2029, USA
Am J Manag Care 7:667-73. 2001..To decompose pharmaceutical spending growth into price and quantity components and to compare growth across different types of health plans...
Role of initial NSAID choice and patient risk factors in the prevention of NSAID gastropathy: a decision analysisA Mark Fendrick
Consortium for Health Outcomes, Innovation, and Cost-Effectiveness Studies (CHOICES, University of Michigan School of Medicine, Ann Arbor, Michigan, USA
Arthritis Rheum 47:36-43. 2002..The impressive impact of ulcer risk on the incremental cost per ulcer prevented warrants increased attention to risk factor identification when NSAIDs are prescribed...
Diagnostic evaluation of the adrenal incidentaloma: decision and cost-effectiveness analysesB A Dwamena
Department of Internal Medicine, School of Public Health, The University of Michigan, and Department of Veteran Affairs Medical Centers, Ann Arbor 48105, USA
J Nucl Med 39:707-12. 1998..The goal of this study was to examine the clinical and economic outcomes of alternative diagnostic strategies for differentiating benign from malignant adrenal masses...
Cost-effectiveness analysis: cardiovascular benefits of proton pump inhibitor co-therapy in patients using aspirin for secondary preventionS D Saini
Center for Clinical Management Research, Ann Arbor VA HSR and D Center of Excellence, Ann Arbor, MI 48105, USA
Aliment Pharmacol Ther 34:243-51. 2011..Many patients with cardiovascular (CV) disease will stop aspirin (ASA) because of ASA-related dyspepsia. Proton pump inhibitor (PPI) co-therapy may reduce ASA-related dyspepsia, enhancing ASA adherence and improving CV outcomes...
Willingness to pay for a quality-adjusted life year: in search of a standardR A Hirth
Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor 48109 2029, USA
Med Decis Making 20:332-42. 2000..With the exception of HK, these far exceed the "rules of thumb" that are frequently used to determine whether an intervention produces an acceptable increase in health benefits in exchange for incremental expenditures...
A national study of the quantity and cost of informal caregiving for the elderly with strokeS L Hickenbottom
Department of Neurology, Consortium for Health Outcomes, Innovation, University of Michigan, Ann Arbor, USA
Neurology 58:1754-9. 2002..As the US population ages, increased stroke incidence will result in higher stroke-associated costs. Although estimates of direct costs exist, little information is available regarding informal caregiving costs for stroke patients...
Cardiologists performing peripheral angioplasties: impact on utilizationD A Axelrod
Robert Wood Johnson Clinical Scholars Program, University of Michigan Medical Center, Ann Arbor, Mich, USA
Eff Clin Pract 4:191-8. 2001..However, cardiologists have recently begun to perform these procedures. It is unknown whether this has affected how often the procedure is done...
Sex differences in severe pulmonary emphysemaFernando J Martinez
University of Michigan, Division of Pulmonary and Critical Care Medicine, Ann Arbor, Michigan 48109 0360, USA
Am J Respir Crit Care Med 176:243-52. 2007..Limited data on sex differences in advanced COPD are available...
The evidence base for the evaluation and management of dizzinessKevin A Kerber
Department of Neurology, University of Michigan Health Systems KAK, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
J Eval Clin Pract 16:186-91. 2010..Dizziness presentations pose many clinical challenges. The objective of this study is to broadly summarize the evidence base that supports clinical decisions in dizziness presentations...
Practical approaches to minimizing gastrointestinal and cardiovascular safety concerns with COX-2 inhibitors and NSAIDsJames M Scheiman
Division of Gastroenterology at the University of Michigan Medical Center, Ann Arbor, Michigan, USA
Arthritis Res Ther 7:S23-9. 2005....
Univariate solutions in a multivariate world: can we afford to practice as in the "good old days"?Laurence F McMahon
Department of Internal Medicine, University of Michigan Health System, 300 North Ingalls, Suite 7C27, Ann Arbor, MI 48109 0429, USA
Am J Manag Care 11:473-6. 2005
Value of computed tomography scans in ED dizziness visits: analysis from a nationally representative sampleKevin A Kerber
Department of Neurology, University of Michigan Health System, Ann Arbor, MI 48109, USA
Am J Emerg Med 28:1030-6. 2010..The study aimed to assess measures of the clinical value of computed tomography (CT) scans in dizziness presentations at the aggregate level...
Cost-effectiveness of full medicare coverage of angiotensin-converting enzyme inhibitors for beneficiaries with diabetesAllison B Rosen
Division of General Medicine, University of Michigan Health Systems, 300 North Ingalls, Suite 7E10, Ann Arbor, MI 48109, USA
Ann Intern Med 143:89-99. 2005..Angiotensin-converting enzyme (ACE) inhibitors slow renal disease progression and reduce cardiac morbidity and mortality in patients with diabetes. Patients' out-of-pocket costs pose a barrier to using this effective therapy...
The effects of a professionally produced videotape on education and anxiety/distress levels for patients with newly diagnosed melanoma: a randomized, prospective clinical trialJeffrey S Orringer
Department of Dermatology, University of Michigan Medical School, Ann Arbor, Michigan, USA
J Am Acad Dermatol 53:224-9. 2005..Secondarily, we sought to compare these effects with those of a traditional clinic visit...
Cost-effectiveness of in-home automated external defibrillators for individuals at increased risk of sudden cardiac deathPeter Cram
Division of General Medicine, Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, USA
J Gen Intern Med 20:251-8. 2005..The current study was conducted to explore the relationship between individuals' risk of cardiac arrest and cost-effectiveness of in-home AED deployment...
Value added radiology: using existing radiology services to improve cancer screeningRuth C Carlos
Department of Radiology, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI 48109-0030, USA
Acad Radiol 12:475-8. 2005
PPI use in the OTC era: who to treat, with what, and for how long?John M Inadomi
Division of Gastroenterology, Department of Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan, USA
Clin Gastroenterol Hepatol 3:208-15. 2005..Ultimately, therapy should be tailored to individual patients because no single strategy will be optimal for the entire population with GERD symptoms...
Provider knowledge, attitudes, and treatment preferences for early pregnancy failureVanessa K Dalton
Department of Obstetrics and Gynecology, University of Michigan Medical School, Ann Arbor, MI, USA
Am J Obstet Gynecol 202:531.e1-8. 2010..We sought to describe health care provider knowledge, attitudes, and treatment preferences for early pregnancy failure (EPF)...
Anxiety is associated with diminished exercise performance and quality of life in severe emphysema: a cross-sectional studyNicholas D Giardino
Mental Health Service, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
Respir Res 11:29. 2010..The purpose of this study is to determine whether there is an association between anxiety and functional measures, quality of life and dyspnea...
Summing the risk of NSAID therapyJames M Scheiman
Division of Gastroenterology, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA
Lancet 369:1580-1. 2007
Impact of fixed-dose combination drugs on adherence to prescription medicationsFeng Pan
Department of Health Management and Policy, University of Michigan, Ann Arbor, MI, USA
J Gen Intern Med 23:611-4. 2008..The inverse correlation between the complexity of a drug regimen and medication adherence is well established. Fixed-dose combination (FDC) therapies are hypothesized to enhance compliance by decreasing the number of required pills...
Longitudinal change in the BODE index predicts mortality in severe emphysemaFernando J Martinez
Division of Pulmonary and Critical Care Medicine, University of Michigan Medical Center, Ann Arbor, Michigan 48109 0360, USA
Am J Respir Crit Care Med 178:491-9. 2008..We hypothesized that decrease in a modified BODE (mBODE) would predict survival in National Emphysema Treatment Trial (NETT) patients...
Can breast and cervical cancer screening visits be used to enhance colorectal cancer screening?Ruth C Carlos
Department of Radiology, University of Michigan, Ann Arbor, Michigan 48109 0030, USA
J Am Coll Radiol 1:769-76. 2004..S. women, adherence with colorectal cancer screening remains suboptimal. A better understanding of the relationship among cancer screening behaviors by women may provide insight into interventions to enhance colorectal cancer screening...
Dizziness presentations in U.S. emergency departments, 1995-2004Kevin A Kerber
Department of Neurology, University of Michigan Health Systems, Ann Arbor, MI, USA
Acad Emerg Med 15:744-50. 2008..The objectives were to describe presentation characteristics and health care utilization information pertaining to dizziness presentations in U.S. emergency departments (EDs) from 1995 through 2004...
Cost-effectiveness of proton pump inhibitor cotherapy in patients taking long-term, low-dose aspirin for secondary cardiovascular preventionSameer D Saini
Department of Internal Medicine, University of Michigan Medical School, 3912 Taubman Center, Ann Arbor, MI 48109 0362, USA
Arch Intern Med 168:1684-90; discussion 1691. 2008..Although these patients are at increased risk for upper gastrointestinal bleeding (UGIB) and proton pump inhibitor (PPI) cotherapy may reduce such risk, it is not known whether lifelong PPI cotherapy is cost-effective...
Prophylactic pacemaker use to allow beta-blocker therapy in patients with chronic heart failure with bradycardiaEric C Stecker
Division of General Medicine, University of Michigan, Ann Arbor, MI, USA
Am Heart J 151:820-8. 2006..CONCLUSION: Prophylactic pacemaker insertion to facilitate beta-blocker treatment in patients with CHF with low resting heart rates has the potential to produce clinical benefits in a highly cost-effective manner...
Predictors of mortality in patients with emphysema and severe airflow obstructionFernando J Martinez
Division of Pulmonary and Critical Care Medicine, University of Michigan Health System, Ann Arbor, MI 48109 0360, and Section of Thoracic Surgery, Beth Israel Deaconess Medical Center, Boston, MA, USA
Am J Respir Crit Care Med 173:1326-34. 2006..Limited data exist describing risk factors for mortality in patients having predominantly emphysema...
Treatment patterns for early pregnancy failure in MichiganVanessa K Dalton
Department of Obstetrics and Gynecology, University of Michigan Medical School, 1500 E Medical Center Drive, L4000, Women s Hospital, Ann Arbor, MI 48109, USA
J Womens Health (Larchmt) 18:787-93. 2009..We describe current treatment patterns for early pregnancy failure (EPF) among women enrolled in two Michigan health plans...
Rising out-of-pocket costs in disease management programsMichael E Chernew
University of Michigan, Ann Arbor, MI 48109 2029, USA
Am J Manag Care 12:150-4. 2006..To document the rise in copayments for patients in disease management programs and to call attention to the inherent conflicts that exist between these 2 approaches to benefit design...
Behavioral associations between prostate and colon cancer screeningRuth C Carlos
Department of Radiology, University of Michigan, Ann Arbor, MI 48109-0030, USA
J Am Coll Surg 200:216-23. 2005..Targeting men who already accept one form of cancer screening can potentially increase CRC screening adherence...
Predicting nursing home admission: estimates from a 7-year follow-up of a nationally representative sample of older AmericansJane Banaszak-Holl
Department of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor, 48109 2029, USA
Alzheimer Dis Assoc Disord 18:83-9. 2004..Interventions for individuals with dementia should impact the behavioral aspects of the condition and slow disease progression in addition to improving physical functioning...
Economic analysis in dermatologyCharles N Ellis
Department of Dermatology, University of Michigan Medical School, Ann Arbor, MI 49109-0314, USA
J Am Acad Dermatol 46:271-83. 2002....
Diagnostic testing or empirical neuraminidase inhibitor therapy for patients with influenza-like illness: what a difference a day makesSusan G Blitz
Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, USA
Am J Manag Care 8:221-7. 2002..Clinicians must consider these factors when determining cost-effective use of NIs...
Percutaneous stenting of incidental unilateral renal artery stenosis: decision analysis of costs and benefitsDavid A Axelrod
Departments of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan 498109 0604, USA
J Endovasc Ther 10:546-56. 2003....
What is the price of life and why doesn't it increase at the rate of inflation?Peter A Ubel
University of Michigan Health Systems 300 N Ingalls, Room 7C27 Ann Arbor, MI 48109 0429, USA
Arch Intern Med 163:1637-41. 2003
Informal caregiving for chronic lung disease among older AmericansKenneth M Langa
Division of General Medicine, Department of Internal Medicine, University of Michigan, 300 North Ingalls Building, Ann Arbor, MI 48109 0429, USA
Chest 122:2197-203. 2002..To obtain nationally representative estimates of the additional time, and related cost, of unpaid family caregiving (informal caregiving) associated with chronic lung disease among older Americans...
Informal caregiving for diabetes and diabetic complications among elderly americansKenneth M Langa
Division of General Medicine, Department of Medicine, University of Michigan, Ann Arbor 48109 0429, USA
J Gerontol B Psychol Sci Soc Sci 57:S177-86. 2002....
Viral respiratory infections due to rhinoviruses: current knowledge, new developmentsA Mark Fendrick
Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, MI, USA
Am J Ther 10:193-202. 2003..By targeting the cause of illness, antiviral agents represent an opportunity to reduce the substantial clinical burden of VRI. Furthermore, effective therapies can potentially reduce inappropriate antibiotic use for viral infections...
Payer type and the returns to bypass surgery: evidence from hospital entry behaviorMichael Chernew
Department of Health Management and Policy, University of Michigan and NBER, Ann Arbor 48109 2029, USA
J Health Econ 21:451-74. 2002..Medicaid appears to reimburse less than average variable costs. HMOs essentially pay at average variable costs, though the return varies inversely with competition...
Homocyst(e)ine and coronary heart disease: pharmacoeconomic support for interventions to lower hyperhomocyst(e)inaemiaBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, B1F245 University Hospital, Ann Arbor, MI 49109 0022, USA
Pharmacoeconomics 20:429-42. 2002....
Effect of off-label use of oncology drugs on pharmaceutical costs: the rituximab experienceDarren Kocs
Divisions of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor 48109-0429, USA
Am J Manag Care 9:393-400; quiz 401-2. 2003..CONCLUSIONS: The off-label use of rituximab is substantial. Projections of oncology-related patterns of care and drug expenditures must account for the potential for off-label use...
Coronary artery bypass grafting in octogenarians: clinical and economic outcomes at community-based healthcare facilitiesBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, USA
Am J Manag Care 8:749-55. 2002..Results of recent studies from high-volume academic centers suggest that coronary artery bypass grafting (CABG) is becoming safer to perform in octogenarians. Similar data from community-based facilities do not exist...
Extent and cost of informal caregiving for older Americans with symptoms of depressionKenneth M Langa
Division of General Medicine, University of Michigan Health System, 300 North Ingalls Building, Room 7E01, Box 0429, Ann Arbor, MI 48109 0429, USA
Am J Psychiatry 161:857-63. 2004..The purpose of this study was to obtain nationally representative estimates of the additional time and cost associated with informal caregiving for older Americans with depressive symptoms...
Cost-effective use of NSAIDs: issues pertinent to coxib use in managed careA Mark Fendrick
Department of Internal Medicine, University of Michigan, Ann Arbor, USA
Am J Manag Care 8:S529-41. 2002....
Associations in breast and colon cancer screening behavior in womenRuth C Carlos
VA Ann Arbor Health Care System, Ann Arbor, MI, USA
Acad Radiol 12:451-8. 2005....
Out-of-pocket health-care expenditures among older Americans with cancerKenneth M Langa
Division of General Medicine Department of Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
Value Health 7:186-94. 2004....
The health effects of restricting prescription medication use because of costMichele Heisler
Veterans Affairs Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
Med Care 42:626-34. 2004..Whether adults experience adverse health outcomes after having restricted medication use because of cost is not known...
Barriers to constraining health care cost growthMichael E Chernew
Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor, MI, USA
Health Aff (Millwood) 23:122-8. 2004..The policy focus should be directed toward encouraging value...
Out-of-pocket health care expenditures among older Americans with dementiaKenneth M Langa
Division of General Medicine, Department of Medicine, University of Michigan Medical School, Ann Arbor, 48109 0429, USA
Alzheimer Dis Assoc Disord 18:90-8. 2004....
Antimicrobial resistance in Streptococcus pneumoniae: implications for patients with community-acquired pneumoniaC E Chenoweth
Department of Internal Medicine, University of Michigan Health System, Ann Arbor 48109 0378, USA
Mayo Clin Proc 75:1161-8. 2000..In this article, we provide an overview of the development of S pneumoniae resistance to commonly used antibiotics and discuss the implications of the development of resistance on treatment decisions...
Electron-beam computed tomography in the diagnosis of coronary artery disease: a meta-analysisB K Nallamothu
B1F245, Division of General Medicine, University Hospital, Ann Arbor, MI 48109 0022, USA
Arch Intern Med 161:833-8. 2001..Before its clinical use is justified, however, the overall accuracy of EBCT must be better defined...
The spectrum of acute bronchitis. Using baseline factors to guide empirical therapyK R Flaherty
University of Michigan Medical School, Ann Arbor, USA
Postgrad Med 109:39-47. 2001..In this article, Drs Flaherty, Saint, Fendrick, and Martinez discuss how an evidence-based approach to treatment may help ensure that efficacious therapy is available in the future...
Management of patients with symptomatic gastroesophageal reflux disease: a primary care perspectiveA M Fendrick
Department of Internal Medicine/Health Management and Policy, Consortium for Health Outcomes, Innovation, and Cost-Effectiveness Studies (CHOICES, Ann Arbor, Michigan, USA
Am J Gastroenterol 96:S29-33. 2001..If proton pump inhibitors consistently reduce the need for physician visits and diagnostic testing, they would seem to be a logical first choice pharmaceutical for individuals who fail to improve with OTC H2 antagonists...
The role of economic evaluation in infection controlS Saint
Division of General Medicine, University of Michigan Health System, Ann Arbor, USA
Am J Infect Control 29:338-44. 2001....
National estimates of the quantity and cost of informal caregiving for the elderly with dementiaK M Langa
Division of General Medicine, Department of Medicine, The Institute for Social Research, University of Michigan, Ann Arbor, Mich, USA
J Gen Intern Med 16:770-8. 2001..We sought to obtain nationally representative estimates of the time and associated cost of informal caregiving for the elderly with mild, moderate, and severe dementia...
Cost-effectiveness of saline-assisted hysterosonography and office hysteroscopy in the evaluation of postmenopausal bleeding: a decision analysisR C Carlos
Department of Radiology, University of Michigan, Ann Arbor 48109-0030, USA
Acad Radiol 8:835-44. 2001..CONCLUSION: HSG depicted more abnormalities at a lower cost per abnormality, which suggests that it should be the preferred initial diagnostic examination in the setting of PMB...
The impact of a celebrity promotional campaign on the use of colon cancer screening: the Katie Couric effectPeter Cram
Division of General Medicine, Department of Internal Medicine, University of Michigan School of Medicine, Ann Arbor, USA
Arch Intern Med 163:1601-5. 2003..These findings suggest that a celebrity spokesperson can have a substantial impact on public participation in preventive care programs...
Incorporating patient-centered outcomes in the analysis of cost-effectiveness: imaging strategies for renovascular hypertensionRuth C Carlos
Department of Radiology, University of Michigan, 1500 E Medical Center Dr, Ann Arbor, MI 48109-0030, USA
AJR Am J Roentgenol 181:1653-61. 2003..CONCLUSION: In the evaluation and treatment of medication-resistant hypertension, strategies that included preliminary imaging saved more lives than did the immediate institution of enhanced medical therapy at a lesser cost...
Influenza. Cost of illness and considerations in the economic evaluation of new and emerging therapiesP Cram
Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, Michigan, USA
Pharmacoeconomics 19:223-30. 2001..In this review, we examine the burden of influenza infection, diagnostic challenges and the clinical and economic impact of available interventions. Clinical controversies and potential areas for further investigation are also explored...
Coronary artery bypass grafting in Native Americans: a higher risk of death compared to other ethnic groups?B K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor 48109 0022, USA
J Gen Intern Med 16:554-9. 2001..While the efficacy and safety of coronary artery bypass grafting (CABG) has been established in several clinical trials, little is known about its outcomes in Native Americans...
Cost-effectiveness of automated external defibrillator deployment in selected public locationsPeter Cram
Division of General Medicine, Department of Internal Medicine, University of Iowa College of Medicine, 200 Hawkins Drive, 6SE GH, Iowa City, IA 52242, USA
J Gen Intern Med 18:745-54. 2003..We sought to evaluate the cost-effectiveness of the AHA recommendation and of AED deployment in selected public locations with known cardiac arrest rates...
Making cost-effectiveness analyses clinically relevant: the effect of provider expertise and biliary disease prevalence on the economic comparison of alternative diagnostic strategiesRuth C Carlos
Department of Radiology, University of Michigan Medical Center, 1500 E Medical Center Dr, Ann Arbor, MI 48109-0030, USA
Acad Radiol 10:620-30. 2003..CONCLUSION: Initial EUS and initial MRCP are less costly than initial ERCP, but provider expertise, biliary disease prevalence, and procedural costs influence incremental cost-effectiveness...
