- The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complexDouglas E Feldman
Department of Molecular Microbiology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
PLoS ONE 8:e57312. 2013..The profound deregulation of TBC1D15 expression exhibited in a diverse array of patient tumors underscores its proposed function as an oncoprotein...
- Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cellsDouglas Edmund Feldman
Department of Molecular Microbiology and Immunology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
Proc Natl Acad Sci U S A 109:829-34. 2012..Differential responses to extrinsic, adipocyte-derived cues may promote the expansion of tumor cell subpopulations and contribute to oncogenesis...