David Feifel

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi The effects of intra-accumbens neurotensin on sensorimotor gating
    D Feifel
    Department of Psychiatry, University of California, San Diego, USA
    Brain Res 760:80-4. 1997
  2. doi Commentary: why diagnose and treat ADHD in adults?
    David Feifel
    Department of Psychiatry, University of California, San Diego, San Diego, CA 92103, USA
    Postgrad Med 120:13-5. 2008
  3. pmc The psychopharmacology of agitation: consensus statement of the american association for emergency psychiatry project Beta psychopharmacology workgroup
    Michael P Wilson
    UC San Diego Health System, Department of Emergency Medicine, San Diego, California
    West J Emerg Med 13:26-34. 2012
  4. doi Adjunctive intranasal oxytocin improves verbal memory in people with schizophrenia
    David Feifel
    Department of Psychiatry, University of California, San Diego, United States
    Schizophr Res 139:207-10. 2012
  5. doi The effects of oxytocin and its analog, carbetocin, on genetic deficits in sensorimotor gating
    David Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 8218, United States
    Eur Neuropsychopharmacol 22:374-8. 2012
  6. ncbi Attention-deficit hyperactivity disorder in adults
    D Feifel
    Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla 92093 0603, USA
    Postgrad Med 100:207-11, 215-8. 1996
  7. ncbi Altered extracellular dopamine concentration in the brains of cholecystokinin-A receptor deficient rats
    David Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neurosci Lett 348:147-50. 2003
  8. ncbi Reversal of sensorimotor gating deficits in Brattleboro rats by acute administration of clozapine and a neurotensin agonist, but not haloperidol: a potential predictive model for novel antipsychotic effects
    David Feifel
    Department of Psychiatry, University of California, San Diego, San Diego, CA 92103 8218, USA
    Neuropsychopharmacology 29:731-8. 2004
  9. pmc Promise and pitfalls of animal models of schizophrenia
    David Feifel
    Department of Psychiatry, University of California, San Diego, 200 West Arbor Drive, San Diego, CA 92103 8218, USA
    Curr Psychiatry Rep 12:327-34. 2010
  10. pmc Effects of neurotensin-2 receptor deletion on sensorimotor gating and locomotor activity
    David Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Behav Brain Res 212:174-8. 2010

Detail Information

Publications61

  1. ncbi The effects of intra-accumbens neurotensin on sensorimotor gating
    D Feifel
    Department of Psychiatry, University of California, San Diego, USA
    Brain Res 760:80-4. 1997
    ..The results suggest that intra-accumbens neurotensin has a significant, dose-dependent effect on sensorimotor gating in which lower doses (0.25-1.0 microg) exhibit a neuroleptic-like action...
  2. doi Commentary: why diagnose and treat ADHD in adults?
    David Feifel
    Department of Psychiatry, University of California, San Diego, San Diego, CA 92103, USA
    Postgrad Med 120:13-5. 2008
    ..An estimated 4% to 5% of the adult population is impaired by ADHD. However,less than one-quarter of these adults have been diagnosed as having ADHD..
  3. pmc The psychopharmacology of agitation: consensus statement of the american association for emergency psychiatry project Beta psychopharmacology workgroup
    Michael P Wilson
    UC San Diego Health System, Department of Emergency Medicine, San Diego, California
    West J Emerg Med 13:26-34. 2012
    ..If agitation results from a delirium or other medical condition, clinicians should first attempt to treat the underlying cause instead of simply medicating with antipsychotics or benzodiazepines...
  4. doi Adjunctive intranasal oxytocin improves verbal memory in people with schizophrenia
    David Feifel
    Department of Psychiatry, University of California, San Diego, United States
    Schizophr Res 139:207-10. 2012
    ..Oxytocin - though it has shown promise as a novel antipsychotic in multiple clinical trials - has as-yet poorly characterized effects on cognition, with some evidence indicating an amnestic profile...
  5. doi The effects of oxytocin and its analog, carbetocin, on genetic deficits in sensorimotor gating
    David Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 8218, United States
    Eur Neuropsychopharmacol 22:374-8. 2012
    ..In contrast to oxytocin, our data do not support the use of carbetocin as an antipsychotic drug...
  6. ncbi Attention-deficit hyperactivity disorder in adults
    D Feifel
    Department of Psychiatry, University of California, San Diego, School of Medicine, La Jolla 92093 0603, USA
    Postgrad Med 100:207-11, 215-8. 1996
    ..When a definitive diagnosis is not possible, a trial of pharmacologic therapy may be appropriate...
  7. ncbi Altered extracellular dopamine concentration in the brains of cholecystokinin-A receptor deficient rats
    David Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Neurosci Lett 348:147-50. 2003
    ..These findings suggest that CCK-A receptors play an important role in the regulation of central DA transmission, and support the notion that the OLETF rat is a useful model to study this regulation...
  8. ncbi Reversal of sensorimotor gating deficits in Brattleboro rats by acute administration of clozapine and a neurotensin agonist, but not haloperidol: a potential predictive model for novel antipsychotic effects
    David Feifel
    Department of Psychiatry, University of California, San Diego, San Diego, CA 92103 8218, USA
    Neuropsychopharmacology 29:731-8. 2004
    ....
  9. pmc Promise and pitfalls of animal models of schizophrenia
    David Feifel
    Department of Psychiatry, University of California, San Diego, 200 West Arbor Drive, San Diego, CA 92103 8218, USA
    Curr Psychiatry Rep 12:327-34. 2010
    ....
  10. pmc Effects of neurotensin-2 receptor deletion on sensorimotor gating and locomotor activity
    David Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Behav Brain Res 212:174-8. 2010
    ..05). These data support the regulation of baseline PPI, ASR and locomotor activity by endogenous NT acting at the NT2 receptor. Further studies investigating the role of NT2 receptors in the modulation of APD-like effects are warranted...
  11. ncbi Inhibitory deficits in ocular motor behavior in adults with attention-deficit/hyperactivity disorder
    David Feifel
    Adult ADHD Program, Department of Psychiatry, University of California, San Diego, La Jolla, California, USA
    Biol Psychiatry 56:333-9. 2004
    ..The ability to suppress unwanted saccadic eye movements is mediated by prefrontal cortex-basal ganglia circuitry and thus constitutes a useful measure of inhibitory ability...
  12. pmc Sensorimotor gating in neurotensin-1 receptor null mice
    D Feifel
    Department of Psychiatry, University of California, San Diego, Medical Center, 200 West Arbor Drive, San Diego, CA 92103 8218, USA
    Neuropharmacology 58:173-8. 2010
    ..We also tested the effects of amphetamine and dizocilpine, a dopamine agonist and NMDA antagonist, respectively, that reduce PPI as well as the NT1 selective receptor agonist PD149163, known to increase PPI in rats...
  13. pmc The acute and subchronic effects of a brain-penetrating, neurotensin-1 receptor agonist on feeding, body weight and temperature
    David Feifel
    Department of Psychiatry, University of California, San Diego Medical Center, 200 West Arbor Drive, San Diego, CA 92103 8218, USA
    Neuropharmacology 58:195-8. 2010
    ..The results suggest that NT1 receptor agonists are candidates for treatment of obesity and that somewhat different mechanisms are involved in NT1-induced feeding regulation and temperature regulation...
  14. pmc The brattleboro rat displays a natural deficit in social discrimination that is restored by clozapine and a neurotensin analog
    D Feifel
    Department of Psychiatry, University of California, San Diego Medical Center, San Diego, CA 92103 8218, USA
    Neuropsychopharmacology 34:2011-8. 2009
    ..The potential of neurotensin agonists as putative treatments for cognitive deficits of schizophrenia was also supported...
  15. doi Attention-deficit/hyperactivity disorder in adults: recognition and diagnosis of this often-overlooked condition
    David Feifel
    Department of Psychiatry, University of California, San Diego, San Diego, CA 92103, USA
    Postgrad Med 120:39-47. 2008
    ....
  16. pmc Prepulse inhibition of startle in adults with ADHD
    David Feifel
    University of California San Diego, School of Medicine, Department of Psychiatry, San Diego, CA 92103 8218, USA
    J Psychiatr Res 43:484-9. 2009
    ..This distinction may be related to a relative sparing of pre-conscious attentional functions in ADHD compared to other disorders with PPI impairment...
  17. ncbi The effects of cross-fostering on inherent sensorimotor gating deficits exhibited by Brattleboro rats
    David Feifel
    Department of Psychiatry, University of California, San Diego, 200 West Arbor Drive, San Diego, CA 92103 8218, USA
    J Gen Psychol 134:173-82. 2007
    ....
  18. ncbi The effects of chronic administration of established and putative antipsychotics on natural prepulse inhibition deficits in Brattleboro rats
    David Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, CA, United States
    Behav Brain Res 181:278-86. 2007
    ..e., peptides) and reasonably model the therapeutic time course of antipsychotic drugs in humans...
  19. doi Further characterization of the predictive validity of the Brattleboro rat model for antipsychotic efficacy
    D Feifel
    Department of Psychiatry, University of California, San Diego, CA 92093 8218, USA
    J Psychopharmacol 25:836-41. 2011
    ..These results suggest that PPI in the BRAT rat responds specifically to drugs with APD efficacy but not psychotropic drugs of different therapeutic families...
  20. ncbi A systemically administered neurotensin agonist blocks disruption of prepulse inhibition produced by a serotonin-2A agonist
    David Feifel
    Department of Psychiatry, University of California, San Diego, USA
    Neuropsychopharmacology 28:651-3. 2003
    ..These findings suggest that, in addition to their established ability to inhibit dopamine transmission, neurotensin agonists may also inhibit 5-HT2A transmission, a pharmacological feature associated with atypical antipsychotic drugs...
  21. ncbi The modulation of sensorimotor gating deficits by mesolimbic cholecystokinin
    D Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla 92093 8620, USA
    Neurosci Lett 229:5-8. 1997
    ..Rather, these results suggest that antagonists of CCK may display neuroleptic-like actions on deficits in PPI and may hold greater promise as antipsychotics...
  22. ncbi Pro-dopamine effects of neurotensin on sensorimotor gating deficits
    D Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, USA
    Peptides 18:1457-60. 1997
    ..This is the first report of a pro-dopamine action for intra-accumbens neurotensin, and suggests that a complex behavioral pharmacology is associated with this neuropeptide...
  23. ncbi Novel antipsychotic-like effects on prepulse inhibition of startle produced by a neurotensin agonist
    D Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla 92093 8620, USA
    J Pharmacol Exp Ther 288:710-3. 1999
    ..These findings suggest that PD149163 has novel antipsychotic-like properties that are distinct from known members of both the "typical" and "atypical" families of antipsychotics...
  24. ncbi Oxytocin modulates psychotomimetic-induced deficits in sensorimotor gating
    D Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla 92093 8620, USA
    Psychopharmacology (Berl) 141:93-8. 1999
    ..These results suggest that oxytocin may play an important role in the modulation of dopaminergic and glutamatergic regulation of PPI, and that it may act as a novel endogenous antipsychotic...
  25. ncbi Attitudes toward psychiatry as a prospective career among students entering medical school
    D Feifel
    Department of Psychiatry, University of California, San Diego 92103 8620, USA
    Am J Psychiatry 156:1397-402. 1999
    ..In order to determine whether this disinclination toward psychiatry occurs before versus during medical school, this study surveyed medical students at the start of their freshman year...
  26. ncbi The effects of subchronic haloperidol on intact and dizocilpine-disrupted sensorimotor gating
    D Feifel
    Department of Psychiatry, University of California, San Diego, 200 West Arbor Drive, San Diego, CA 92103 8620, USA
    Psychopharmacology (Berl) 146:175-9. 1999
    ..Acute administration of antipsychotics tends to facilitate baseline PPI. However, the effect is generally not large enough in magnitude nor reliable enough to be considered a useful preclinical screen for antipsychotic activity...
  27. ncbi Individual differences in prepulse inhibition of startle as a measure of individual dopamine function
    D Feifel
    Department of Psychiatry, University of California, San Diego 92103 8620, USA
    Behav Neurosci 113:1020-9. 1999
    ....
  28. ncbi Effects of neurotensin administered into the ventral tegmental area on prepulse inhibition of startle
    D Feifel
    Department of Psychiatry, University of California, San Diego, Medical Center, 92103 8620, USA
    Behav Brain Res 106:189-93. 1999
    ..These results suggest that PPI and locomotor activity may have dissociable mesolimbic substrates and that neurotensin in the VTA does not play an important role in regulating PPI...
  29. ncbi Rationale and guidelines for the inpatient treatment of acute psychosis
    D Feifel
    Neuropsychiatry and Behavioral Medicine Unit, University of California, San Diego Medical Center, 92103 8218, USA
    J Clin Psychiatry 61:27-32. 2000
    ..This article presents the rationale and practical guidelines for selection of treatment regimens for patients hospitalized due to acute psychosis...
  30. ncbi Startle and sensorimotor gating in rats lacking CCK-A receptors
    D Feifel
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093 8218, USA
    Neuropsychopharmacology 24:663-70. 2001
    ....
  31. pmc Clozapine and PD149163 elevate prepulse inhibition in Brown Norway rats
    David Feifel
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 8218, USA
    Behav Neurosci 125:268-72. 2011
    ..The results also add to the evidence suggesting that PD149163 may have antipsychotic properties...
  32. pmc The reversal of amphetamine-induced locomotor activation by a selective neurotensin-1 receptor agonist does not exhibit tolerance
    David Feifel
    Department of Psychiatry, UCSD Medical Center, University of California, San Diego, 200 West Arbor Drive, San Diego, CA, USA
    Psychopharmacology (Berl) 200:197-203. 2008
    ....
  33. doi A naturalistic study of intramuscular haloperidol versus intramuscular olanzapine for the management of acute agitation
    Kai MacDonald
    Department of Psychiatry, University of California, San Diego, CA 92093 0804, USA
    J Clin Psychopharmacol 32:317-22. 2012
    ..Therefore, we conducted a retrospective chart review to compare IM olanzapine and haloperidol in a "real-world" population with agitation...
  34. pmc The relationship between sensorimotor gating and clinical improvement in acutely ill schizophrenia patients
    Arpi Minassian
    Department of Psychiatry, University of California, San Diego School of Medicine, USA
    Schizophr Res 89:225-31. 2007
    ..Our results suggest that PPI can be improved by short-term treatment, and that improvement in sensorimotor gating is associated with treatment-related improvement of symptoms of schizophrenia...
  35. doi A comparison of the safety of olanzapine and haloperidol in combination with benzodiazepines in emergency department patients with acute agitation
    Michael P Wilson
    Department of Emergency Medicine, University of California, San Diego Medical Center, San Diego, California 92103, USA
    J Emerg Med 43:790-7. 2012
    ..The combination of olanzapine + benzodiazepines is not recommended by the manufacturer, but a recent report suggested harm only if the patient was intoxicated. Whether this is also true for haloperidol + benzodiazepines is not known...
  36. doi A retrospective analysis of intramuscular haloperidol and intramuscular olanzapine in the treatment of agitation in drug- and alcohol-using patients
    Kai MacDonald
    Department of Psychiatry, University of California, San Diego, San Diego, CA 92093, USA
    Gen Hosp Psychiatry 32:443-5. 2010
    ..The treatment of agitation in drug- and alcohol-using emergency patients is understudied...
  37. ncbi Information processing deficits in acutely psychotic schizophrenia patients medicated and unmedicated at the time of admission
    William Perry
    Neuropsychiatry and Behavioral Medicine Service, Department of Psychiatry, University of California San Diego, La Jolla 92093 8620, USA
    Am J Psychiatry 159:1375-81. 2002
    ..The present study investigated the effects of antipsychotics on prepulse inhibition and startle habituation in acutely hospitalized patients with schizophrenia...
  38. ncbi Sensorimotor gating effects produced by repeated dopamine agonists in a paradigm favoring environmental conditioning
    David Feifel
    Department of Psychiatry, University of California, San Diego, 200 West Arbor Drive, San Diego, CA 92103 8218, USA
    Psychopharmacology (Berl) 162:138-46. 2002
    ..Differences in methodology (e.g. drug-environment pairing) may have contributed to these contradictory findings...
  39. doi Potential complications of combining intramuscular olanzapine with benzodiazepines in emergency department patients
    Michael P Wilson
    Department of Emergency Medicine, University of California, San Diego Medical Center, San Diego, California 92103, USA
    J Emerg Med 43:889-96. 2012
    ..The potential complications of the use of olanzapine in combination with a benzodiazepine have not been well characterized in ED patients with undifferentiated agitation...
  40. doi Adjunctive intranasal oxytocin reduces symptoms in schizophrenia patients
    David Feifel
    Department of Psychiatry, University of California, San Diego Medical Center, San Diego, California 92103 8218, USA
    Biol Psychiatry 68:678-80. 2010
    ..Both human and animal studies suggest oxytocin may have antipsychotic properties. Therefore, we conducted a clinical trial to directly test this notion...
  41. ncbi Upregulation of striatal dopamine-2 receptors in Brattleboro rats with prepulse inhibition deficits
    Paul D Shilling
    Department of Psychiatry, University of California, San Diego, California 92103 8218, USA
    Biol Psychiatry 60:1278-81. 2006
    ..We sought to determine whether they also have increases in striatal dopamine-2 (D2) receptors found in some studies examining the brains of schizophrenia patients...
  42. ncbi The effects of systemic NT69L, a neurotensin agonist, on baseline and drug-disrupted prepulse inhibition
    P D Shilling
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Behav Brain Res 143:7-14. 2003
    ....
  43. ncbi SR146131, a cholecystokinin-A receptor agonist, antagonizes prepulse inhibition deficits produced by dizocilpine and DOI
    P D Shilling
    Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
    Psychopharmacology (Berl) 164:285-93. 2002
    ..SR146131, a CCK-A selective nonpeptide agonist, has recently been developed (Sanofi-Synthelabo)...
  44. ncbi Decreased haloperidol-induced potentiation of zif268 mRNA expression in the nucleus accumbens shell and the dorsal lateral striatum of rats lacking cholecystokinin-A receptors
    P D Shilling
    Department of Psychiatry, University of California, San Diego, California 92093, USA
    Synapse 43:134-8. 2002
    ..05), but not in the NA core, in OLETF rats compared to LETO rats. These data suggest that CCK-A receptor mechanisms may contribute to the therapeutic and the extrapyramidal motor effects associated with antipsychotic drug treatment...
  45. ncbi Vasopressin-deficient rats exhibit sensorimotor gating deficits that are reversed by subchronic haloperidol
    D Feifel
    Department of Psychiatry, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103, USA
    Biol Psychiatry 50:425-33. 2001
    ....
  46. ncbi Extended release quetiapine fumarate monotherapy in major depressive disorder: a placebo- and duloxetine-controlled study
    Andrew J Cutler
    Department of Psychiatry, University of Florida, Gainesville, FL, USA
    J Clin Psychiatry 70:526-39. 2009
    ..To evaluate the efficacy and tolerability of once-daily extended release quetiapine fumarate (quetiapine XR) as monotherapy treatment for major depressive disorder (MDD)...
  47. doi The neurotensin-1 receptor agonist PD149163 blocks fear-potentiated startle
    Paul D Shilling
    Department of Psychiatry, UCSD, 200 West Arbor Drive, San Diego, CA 92103 8218, USA
    Pharmacol Biochem Behav 90:748-52. 2008
    ..05). These data suggest that systemically administered NT1 agonists modulate the neural circuitry that regulates fear and anxiety to produce dose-dependent anxiolytic-like effects on FPS...
  48. doi The effect of intranasal oxytocin treatment on conditioned fear extinction and recall in a healthy human sample
    Dean Acheson
    Department of Psychiatry, University of California, San Diego, CA, USA
    Psychopharmacology (Berl) 229:199-208. 2013
    ..Little is known, however, about the effects of OT treatment on conditioned fear responding and extinction in humans...
  49. ncbi Prepulse inhibition in patients with non-psychotic major depressive disorder
    William Perry
    Department of Psychiatry, University of California San Diego, 200 West Arbor Drive, Mailcode 8218, San Diego, CA 92103 8218, USA
    J Affect Disord 81:179-84. 2004
    ..Therefore, we assessed PPI in non-psychotic MDD patients and compared their results to schizophrenia patients and non-patients...
  50. ncbi Rapid oral loading of extended release divalproex in patients with acute mania
    Brian P Miller
    Neuropsychiatry and Behavioral Medicine Unit, University of California, San Diego Medical Center, San Diego, California 92103 8218, USA
    Gen Hosp Psychiatry 27:218-21. 2005
    ..Recently, an extended release formulation of divalproex sodium (divalproex ER) was approved for treatment of migraine headaches. This formulation may be a useful treatment option for patients with acute mania...
  51. pmc A Naturalistic, Single-blind Comparison of Rapid Dose Administration of Divalproex ER Versus Quetiapine in Patients with Acute Bipolar Mania
    David Feifel
    All from the Department of Psychiatry, University of California San Diego Medical Center, San Diego, California
    Innov Clin Neurosci 8:29-35. 2011
    ..Conclusion: Results of this small study indicate that rapid-dose administration of both quetiapine and divalproex ER produce rapid improvement in acute mania within the first seven days and both seem to be well tolerated...
  52. ncbi A systematic review of modafinil: Potential clinical uses and mechanisms of action
    Jacob S Ballon
    Department of Psychiatry, University of California, San Diego, CA, USA
    J Clin Psychiatry 67:554-66. 2006
    ..It is a well-tolerated medication with low propensity for abuse and is frequently used for off-label indications. The objective of this study was to systematically review the available evidence supporting the clinical use of modafinil...
  53. doi Intramuscular ziprasidone: influence of alcohol and benzodiazepines on vital signs in the emergency setting
    Michael P Wilson
    Department of Emergency Medicine Behavioral Emergencies Research Laboratory Department of Emergency Medicine, UC San Diego Health System, San Diego, California
    J Emerg Med 45:901-8. 2013
    ....
  54. doi Oxytocin and psychotherapy: a pilot study of its physiological, behavioral and subjective effects in males with depression
    Kai MacDonald
    University of California, San Diego Medical Center, Department of Psychiatry, United States Electronic address
    Psychoneuroendocrinology 38:2831-43. 2013
    ..Moreover, the similarity of some of these acute effects to those of single-dose serotonergic antidepressants raises interesting questions about the potential antidepressant benefits of chronic OT administration...
  55. doi Dramatic improvement in sexual function induced by intranasal oxytocin
    Kai MacDonald
    University of California, San Diego Medical Center Department of Psychiatry, San Diego, CA 92103 8218, USA
    J Sex Med 9:1407-10. 2012
    ..This is a case report on a male who had significant, broad-spectrum improvements in sexual function during a course of intranasal oxytocin treatment for social anxiety...
  56. ncbi A double-blind, placebo-controlled trial of dexmethylphenidate hydrochloride and d,l-threo-methylphenidate hydrochloride in children with attention-deficit/hyperactivity disorder
    Sharon Wigal
    Irvine Child Development Center, University of California, Irvine, CA 92612, USA
    J Am Acad Child Adolesc Psychiatry 43:1406-14. 2004
    ....
  57. ncbi Neurotensin agonists block the prepulse inhibition deficits produced by a 5-HT2A and an alpha1 agonist
    P D Shilling
    Department of Psychiatry, University of California San Diego, La Jolla, CA 92093, USA
    Psychopharmacology (Berl) 175:353-9. 2004
    ..This suggested that NT agonists could inhibit 5-HT2A modulation of neurotransmission...
  58. ncbi Sensorimotor gating deficits in bipolar disorder patients with acute psychotic mania
    W Perry
    Department of Psychiatry, University of California at San Diego, 200 West Arbor Drive, Mail Code 8218, La Jolla, CA 92093-8620, USA
    Biol Psychiatry 50:418-24. 2001
    ....
  59. ncbi Acute treatment of psychotic agitation: a randomized comparison of oral treatment with risperidone and lorazepam versus intramuscular treatment with haloperidol and lorazepam
    Glenn W Currier
    Departments of Psychiatry and Emergency Medicine, University of Rochester Medical Center, 300 Crittenden Boulevard, Rochester, N Y 14642, USA
    J Clin Psychiatry 65:386-94. 2004
    ..We hypothesized that the efficacy and speed of action of both treatments would be similar...
  60. ncbi Dosing of divalproex extended release
    David Feifel
    J Clin Psychiatry 68:1146-7; author reply 1147. 2007

Research Grants10

  1. Antipsychotic-Like Drug Effects of Neurotensin
    David Feifel; Fiscal Year: 2004
    ....
  2. A Novel Animal Model of Relevance to Schizophrenia
    David Feifel; Fiscal Year: 2007
    ..The successful development of this animal model could significantly enhance the understanding of the underlying causes of schizophrenia-associated abnormalities and improve drug discovery. ..
  3. A Novel Animal Model of Relevance to Schizophrenia
    David Feifel; Fiscal Year: 2009
    ..The successful development of this animal model could significantly enhance the understanding of the underlying causes of schizophrenia-associated abnormalities and improve drug discovery. ..
  4. Neurotensin-1 Receptor as a Therapeutic Target for Schizophrenia
    David Feifel; Fiscal Year: 2010
    ..The proposed experiments may help lead to completely novel and superior treatments for schizophrenia. ..
  5. Antipsychotic-Like Drug Effects of Neurotensin
    David Feifel; Fiscal Year: 2002
    ....
  6. A Novel Animal Model of Relevance to Schizophrenia
    David Feifel; Fiscal Year: 2006
    ..The successful development of this animal model could significantly enhance the understanding of the underlying causes of schizophrenia-associated abnormalities and improve drug discovery. ..
  7. Neurotensin-1 Receptor as a Therapeutic Target for Schizophrenia
    David Feifel; Fiscal Year: 2009
    ..The proposed experiments may help lead to completely novel and superior treatments for schizophrenia. ..
  8. A Novel Animal Model of Relevance to Schizophrenia
    David Feifel; Fiscal Year: 2005
    ..The successful development of this animal model could significantly enhance the understanding of the underlying causes of schizophrenia-associated abnormalities and improve drug discovery. ..
  9. Antipsychotic-Like Drug Effects of Neurotensin
    David Feifel; Fiscal Year: 2003
    ....