D E Featherstone

Summary

Affiliation: University of Utah
Country: USA

Publications

  1. ncbi request reprint Wrestling with pleiotropy: genomic and topological analysis of the yeast gene expression network
    David E Featherstone
    Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
    Bioessays 24:267-74. 2002
  2. pmc A defect in skeletal muscle sodium channel deactivation exacerbates hyperexcitability in human paramyotonia congenita
    D E Featherstone
    Department of Biology, Utah State University, Logan 84322 5305, USA
    J Physiol 506:627-38. 1998
  3. ncbi request reprint Developmental regulation of glutamate receptor field size by nonvesicular glutamate release
    David E Featherstone
    Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112 0840, USA
    Nat Neurosci 5:141-6. 2002
  4. ncbi request reprint Surprises from Drosophila: genetic mechanisms of synaptic development and plasticity
    D E Featherstone
    Department of Biology, University of Utah, Salt Lake City, UT 84112 0840, USA
    Brain Res Bull 53:501-11. 2000
  5. pmc Interaction between fast and slow inactivation in Skm1 sodium channels
    D E Featherstone
    Department of Biology, Utah State University, Logan 84322 5305, USA
    Biophys J 71:3098-109. 1996
  6. ncbi request reprint Drosophila alpha- and beta-spectrin mutations disrupt presynaptic neurotransmitter release
    D E Featherstone
    Department of Biology, University of Utah, Salt Lake City, Utah 84112 0840, USA
    J Neurosci 21:4215-24. 2001
  7. ncbi request reprint Presynaptic glutamic acid decarboxylase is required for induction of the postsynaptic receptor field at a glutamatergic synapse
    D E Featherstone
    Department of Biology, University of Utah, Salt Lake City 84112, USA
    Neuron 27:71-84. 2000
  8. pmc Human Na+ channel fast and slow inactivation in paramyotonia congenita mutants expressed in Xenopus laevis oocytes
    J E Richmond
    Department of Biology, Utah State University, Logan 84322 5305, USA
    J Physiol 499:589-600. 1997
  9. pmc A glial amino-acid transporter controls synapse strength and courtship in Drosophila
    Yael Grosjean
    Biological Sciences, University of Illinois at Chicago, Chicago, IL, USA
    Nat Neurosci 11:54-61. 2008
  10. pmc An essential Drosophila glutamate receptor subunit that functions in both central neuropil and neuromuscular junction
    David E Featherstone
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    J Neurosci 25:3199-208. 2005

Collaborators

Detail Information

Publications20

  1. ncbi request reprint Wrestling with pleiotropy: genomic and topological analysis of the yeast gene expression network
    David E Featherstone
    Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, UT 84112, USA
    Bioessays 24:267-74. 2002
    ..Using principles of scale-free network topology, we propose that fragmenting the gene expression network via "genome-engineering" may be a viable and practical approach to isolating gene function...
  2. pmc A defect in skeletal muscle sodium channel deactivation exacerbates hyperexcitability in human paramyotonia congenita
    D E Featherstone
    Department of Biology, Utah State University, Logan 84322 5305, USA
    J Physiol 506:627-38. 1998
    ..Hyperexcitability due to slowed deactivation, which has previously been overlooked, also predicts the temperature sensitivity of PC, which has otherwise not been adequately explained...
  3. ncbi request reprint Developmental regulation of glutamate receptor field size by nonvesicular glutamate release
    David E Featherstone
    Department of Biology, University of Utah, 257 South 1400 East, Salt Lake City, Utah 84112 0840, USA
    Nat Neurosci 5:141-6. 2002
    ..Our results reveal an elegant mechanism for receptor field regulation during synaptogenesis and reveal a nonpathological role for nonvesicular glutamate release at the synapse...
  4. ncbi request reprint Surprises from Drosophila: genetic mechanisms of synaptic development and plasticity
    D E Featherstone
    Department of Biology, University of Utah, Salt Lake City, UT 84112 0840, USA
    Brain Res Bull 53:501-11. 2000
    ..The requirement for these proteins at the NMJ highlights the fact that synaptic development and plasticity involves intense inter- and intracellular signaling about which we know almost nothing...
  5. pmc Interaction between fast and slow inactivation in Skm1 sodium channels
    D E Featherstone
    Department of Biology, Utah State University, Logan 84322 5305, USA
    Biophys J 71:3098-109. 1996
    ..3) Selective removal of fast inactivation by IFM1303QQQ allows slow inactivation to occur more quickly and completely than in WT. We conclude that fast inactivation reduces the probability of subsequent slow inactivation...
  6. ncbi request reprint Drosophila alpha- and beta-spectrin mutations disrupt presynaptic neurotransmitter release
    D E Featherstone
    Department of Biology, University of Utah, Salt Lake City, Utah 84112 0840, USA
    J Neurosci 21:4215-24. 2001
    ....
  7. ncbi request reprint Presynaptic glutamic acid decarboxylase is required for induction of the postsynaptic receptor field at a glutamatergic synapse
    D E Featherstone
    Department of Biology, University of Utah, Salt Lake City 84112, USA
    Neuron 27:71-84. 2000
    ..These data demonstrate that GAD plays an unexpected role in glutamatergic synaptogenesis...
  8. pmc Human Na+ channel fast and slow inactivation in paramyotonia congenita mutants expressed in Xenopus laevis oocytes
    J E Richmond
    Department of Biology, Utah State University, Logan 84322 5305, USA
    J Physiol 499:589-600. 1997
    ..With this protocol, we found that R1448C and T1313M were similar in that they maintained a significantly higher channel availability during high frequency activity, compared with WT...
  9. pmc A glial amino-acid transporter controls synapse strength and courtship in Drosophila
    Yael Grosjean
    Biological Sciences, University of Illinois at Chicago, Chicago, IL, USA
    Nat Neurosci 11:54-61. 2008
    ....
  10. pmc An essential Drosophila glutamate receptor subunit that functions in both central neuropil and neuromuscular junction
    David E Featherstone
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    J Neurosci 25:3199-208. 2005
    ..These studies reveal GluRIID as a newly identified glutamate receptor subunit that is essential for glutamate receptor assembly/stabilization in the peripheral NMJ and required for properly patterned motor output in the CNS...
  11. pmc The 4.1 protein coracle mediates subunit-selective anchoring of Drosophila glutamate receptors to the postsynaptic actin cytoskeleton
    Kaiyun Chen
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    J Neurosci 25:6667-75. 2005
    ....
  12. pmc Increased synaptic microtubules and altered synapse development in Drosophila sec8 mutants
    Faith L W Liebl
    Department of Cell and Structural Biology, University of Illinois at Urbana Champaign, 601 South Goodwin Avenue, C626, Urbana, IL 61801, USA
    BMC Biol 3:27. 2005
    ..However, these models have never been tested in vivo. Nervous system development and function have not been described after mutation of sec8 in any organism...
  13. pmc Nonvesicular release of glutamate by glial xCT transporters suppresses glutamate receptor clustering in vivo
    Hrvoje Augustin
    Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    J Neurosci 27:111-23. 2007
    ....
  14. pmc Derailed regulates development of the Drosophila neuromuscular junction
    Faith L W Liebl
    Cell and Developmental Biology Program, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    Dev Neurobiol 68:152-65. 2008
    ..Our findings reveal a novel signaling mechanism that regulates morphology of the Drosophila NMJ...
  15. pmc Regulation of synaptic transmission by ambient extracellular glutamate
    David E Featherstone
    Department of Biological Sciences, University of Illinois at Chicago 60607, USA
    Neuroscientist 14:171-81. 2008
    ..Unfortunately, the mechanisms regulating ambient extracellular glutamate and glutamate receptor desensitization remain poorly understood and understudied...
  16. pmc Genome-wide P-element screen for Drosophila synaptogenesis mutants
    Faith L W Liebl
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois 60607, USA
    J Neurobiol 66:332-47. 2006
    ....
  17. pmc A single vesicular glutamate transporter is sufficient to fill a synaptic vesicle
    Richard W Daniels
    Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neuron 49:11-6. 2006
    ..Consistent with the presence of empty vesicles, at dvglut mutant synapses synaptic vesicles are smaller, suggesting that vesicle filling and/or transporter level is an important determinant of vesicle size...
  18. pmc Genes involved in Drosophila glutamate receptor expression and localization
    Faith L W Liebl
    Dept of Cell and Structural Biology, Univ of Illinois at Urbana Champaign, Urbana, USA
    BMC Neurosci 6:44. 2005
    ..We screened transposon mutants generated by the ongoing Drosophila Gene Disruption Project in an effort to identify the different types of genes required for glutamate receptor cluster development...
  19. pmc Discs-large (DLG) is clustered by presynaptic innervation and regulates postsynaptic glutamate receptor subunit composition in Drosophila
    Kaiyun Chen
    Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA
    BMC Biol 3:1. 2005
    ....
  20. pmc Hemolymph amino acid analysis of individual Drosophila larvae
    Sujeewa C Piyankarage
    Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, IL 60607, USA
    Anal Chem 80:1201-7. 2008
    ....