Thomas G Fazzio

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity
    Thomas G Fazzio
    Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
    Cell 134:162-74. 2008
  2. ncbi Chromatin regulation Tip(60)s the balance in embryonic stem cell self-renewal
    Thomas G Fazzio
    The G W Hooper Research Foundation, University of California San Francisco, San Francisco, California 94143 0552, USA
    Cell Cycle 7:3302-6. 2008
  3. ncbi Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells
    Thomas G Fazzio
    Biochemistry and Biophysics Department, University of California, San Francisco, San Francisco, CA 94158, USA
    J Cell Biol 188:491-503. 2010
  4. ncbi Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome
    Dmitri A Nusinow
    Department of Biochemistry and Biophysics, University of California, San Francisco, California 94158, USA
    J Biol Chem 282:12851-9. 2007
  5. ncbi Assembly of yeast chromatin using ISWI complexes
    Jay C Vary
    Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195, USA
    Methods Enzymol 375:88-102. 2004
  6. ncbi Two distinct mechanisms of chromatin interaction by the Isw2 chromatin remodeling complex in vivo
    Thomas G Fazzio
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Mail stop A1 162, P O Box 19024, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Mol Cell Biol 25:9165-74. 2005

Collaborators

Detail Information

Publications6

  1. ncbi An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity
    Thomas G Fazzio
    Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA
    Cell 134:162-74. 2008
    ..Depletion of Nanog reduces p400 binding to target promoters without affecting H3K4me3 levels. Together, these data indicate that Tip60-p400 integrates signals from Nanog and H3K4me3 to regulate gene expression in ESCs...
  2. ncbi Chromatin regulation Tip(60)s the balance in embryonic stem cell self-renewal
    Thomas G Fazzio
    The G W Hooper Research Foundation, University of California San Francisco, San Francisco, California 94143 0552, USA
    Cell Cycle 7:3302-6. 2008
    ..Rather, we propose that the impact of specific modifications at each promoter is determined by the chromatin context in which they are found...
  3. ncbi Condensin complexes regulate mitotic progression and interphase chromatin structure in embryonic stem cells
    Thomas G Fazzio
    Biochemistry and Biophysics Department, University of California, San Francisco, San Francisco, CA 94158, USA
    J Cell Biol 188:491-503. 2010
    ..The altered compaction coincided with alterations in the abundance of several epigenetic modifications. These data reveal a unique role for condensin complexes in interphase chromatin compaction in ES cells...
  4. ncbi Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome
    Dmitri A Nusinow
    Department of Biochemistry and Biophysics, University of California, San Francisco, California 94158, USA
    J Biol Chem 282:12851-9. 2007
    ..These results suggest that one function of macroH2A in gene silencing is to inhibit PARP-1 enzymatic activity, and this may affect PARP-1 association with chromatin...
  5. ncbi Assembly of yeast chromatin using ISWI complexes
    Jay C Vary
    Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195, USA
    Methods Enzymol 375:88-102. 2004
  6. ncbi Two distinct mechanisms of chromatin interaction by the Isw2 chromatin remodeling complex in vivo
    Thomas G Fazzio
    Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Mail stop A1 162, P O Box 19024, 1100 Fairview Avenue North, Seattle, WA 98109 1024, USA
    Mol Cell Biol 25:9165-74. 2005
    ..We propose a model for target recognition and chromatin remodeling by Isw2 complex in vivo...