Research Topics
| Justin M FarookSummaryAffiliation: University of Kentucky Country: USA Publications
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Publications
Topiramate (Topamax) reduces conditioned abstinence behaviours and handling-induced convulsions (HIC) after chronic administration of alcohol in Swiss-Webster miceJustin M Farook
Department of Psychology, Kastle Hall, University of Kentucky, Lexington, Kentucky 40506, USA
Alcohol Alcohol 42:296-300. 2007..Recent studies have shown that topiramate reduces harmful drinking and initiates abstinence in humans, but little is known as to why this drug is effective...
Acamprosate attenuates the handling induced convulsions during alcohol withdrawal in Swiss Webster miceJustin M Farook
Department of Psychology, University of Kentucky, Lexington, KY 40506, USA
Physiol Behav 95:267-70. 2008..05). This study supports the use of acamprosate during periods of alcohol withdrawal as well as during abstinence...
Topiramate attenuates the stress-induced increase in alcohol consumption and preference in male C57BL/6J miceJustin M Farook
Department of Psychology, University of Kentucky, Lexington, Kentucky 40506, USA
Physiol Behav 96:189-93. 2009..This experiment suggests that one mechanism of topiramate in reducing alcohol consumption and alcohol preference may involve an interaction with stress...
Lobeline, a nicotinic partial agonist attenuates alcohol consumption and preference in male C57BL/6J miceJustin M Farook
Department of Pharmaceutical Science, University of Kentucky, Lexington, Kentucky 40536, USA
Physiol Behav 97:503-6. 2009..These results provide support that nicotinic receptor based drugs may be useful as potential treatments for alcoholism...
Effects of mecamylamine on alcohol consumption and preference in male C57BL/6J miceJustin M Farook
Department of Psychology, College of Pharmacy, University of Kentucky, Lexington, KY 40506, USA
Pharmacology 83:379-84. 2009..These results provide further support that mecamylamine is effective in reducing alcohol consumption and preference, and nicotinic-receptor-based drugs could further be explored as potential treatments for alcoholism...
Alcohol withdrawal-induced hippocampal neurotoxicity in vitro and seizures in vivo are both reduced by memantineTRACY D STEPANYAN
Department of Molecular and Biomedical Pharmacology, College of Medicine, University of Kentucky, Lexington, Kentucky, USA
Alcohol Clin Exp Res 32:2128-35. 2008..An exception is the moderate affinity NMDAR channel blocker memantine, used in Alzheimer's dementia. The present studies examined the ability of memantine to protect against EWD-related toxicity in vitro and seizures in vivo...
