A M Farese

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi A single dose of pegylated leridistim significantly improves neutrophil recovery in sublethally irradiated rhesus macaques
    A M Farese
    University of Maryland, Greenebaum Cancer Center, 655 West Baltimore Street, BRB 7 049, Baltimore, MD 21201, USA
    Stem Cells 19:514-21. 2001
  2. ncbi Leridistim, a chimeric dual G-CSF and IL-3 receptor agonist, enhances multilineage hematopoietic recovery in a nonhuman primate model of radiation-induced myelosuppression: effect of schedule, dose, and route of administration
    A M Farese
    University of Maryland, Greenebaum Cancer Center, 655 West Baltimore Street, BRB 7 049, Baltimore, MD 21201, USA
    Stem Cells 19:522-33. 2001
  3. ncbi Hematopoietic recovery following autologous bone marrow transplantation in a nonhuman primate: effect of variation in treatment schedule with PEG-rHuMGDF
    Ann M Farese
    University of Maryland Greenebaum Cancer Center, Baltimore, Maryland 21201, USA
    Stem Cells 21:79-89. 2003
  4. ncbi Myelopoietin, a chimeric agonist of human interleukin 3 and granulocyte colony-stimulating factor receptors, mobilizes CD34+ cells that rapidly engraft lethally x-irradiated nonhuman primates
    T J MacVittie
    Greenebaum Cancer Center, Baltimore, MD 21201, USA
    Exp Hematol 27:1557-68. 1999
  5. ncbi Promegapoietin-1a, an engineered chimeric IL-3 and Mpl-L receptor agonist, stimulates hematopoietic recovery in conventional and abbreviated schedules following radiation-induced myelosuppression in nonhuman primates
    A M Farese
    Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland 21201, USA
    Stem Cells 19:329-38. 2001
  6. ncbi Pegfilgrastim administered in an abbreviated schedule, significantly improved neutrophil recovery after high-dose radiation-induced myelosuppression in rhesus macaques
    A M Farese
    Department of Radiation Oncology, University of Maryland, School of Medicine, Baltimore, MD 21201, USA
    Radiat Res 178:403-13. 2012
  7. ncbi Pegfilgrastim, a sustained-duration form of filgrastim, significantly improves neutrophil recovery after autologous marrow transplantation in rhesus macaques
    A M Farese
    Greenebaum Cancer Center, University of Maryland, Baltimore, MD 21201, USA
    Bone Marrow Transplant 32:399-404. 2003
  8. ncbi Defining the full therapeutic potential of recombinant growth factors in the post radiation-accident environment: the effect of supportive care plus administration of G-CSF
    Thomas J MacVittie
    Marlene and Stewart Greenebaum Cancer Center, Bressler Research Building, Room 7 039, University of Maryland Baltimore, 655 West Baltimore Street, Baltimore, MD 21201, USA
    Health Phys 89:546-55. 2005
  9. ncbi Polyclonal long-term MFGS-gp91phox marking in rhesus macaques after nonmyeloablative transplantation with transduced autologous peripheral blood progenitor cells
    Sebastian Brenner
    Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Ther 14:202-11. 2006
  10. ncbi The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action
    Dirk E Smith
    Amgen Corporation, 51 University Street, Seattle, WA 98101, USA
    Immunity 18:87-96. 2003

Collaborators

Detail Information

Publications12

  1. ncbi A single dose of pegylated leridistim significantly improves neutrophil recovery in sublethally irradiated rhesus macaques
    A M Farese
    University of Maryland, Greenebaum Cancer Center, 655 West Baltimore Street, BRB 7 049, Baltimore, MD 21201, USA
    Stem Cells 19:514-21. 2001
    ....
  2. ncbi Leridistim, a chimeric dual G-CSF and IL-3 receptor agonist, enhances multilineage hematopoietic recovery in a nonhuman primate model of radiation-induced myelosuppression: effect of schedule, dose, and route of administration
    A M Farese
    University of Maryland, Greenebaum Cancer Center, 655 West Baltimore Street, BRB 7 049, Baltimore, MD 21201, USA
    Stem Cells 19:522-33. 2001
    ..Leridistim, a novel engineered hematopoietic growth factor administered at the appropriate dose, route and schedule, stimulates multilineage hematopoietic reconstitution in radiation-myelosuppressed nonhuman primates...
  3. ncbi Hematopoietic recovery following autologous bone marrow transplantation in a nonhuman primate: effect of variation in treatment schedule with PEG-rHuMGDF
    Ann M Farese
    University of Maryland Greenebaum Cancer Center, Baltimore, Maryland 21201, USA
    Stem Cells 21:79-89. 2003
    ..These data confirm predictions from PK/PD modeling of PEG-rHuMGDF that thrombocytopenia is preventable following AuBMT...
  4. ncbi Myelopoietin, a chimeric agonist of human interleukin 3 and granulocyte colony-stimulating factor receptors, mobilizes CD34+ cells that rapidly engraft lethally x-irradiated nonhuman primates
    T J MacVittie
    Greenebaum Cancer Center, Baltimore, MD 21201, USA
    Exp Hematol 27:1557-68. 1999
    ....
  5. ncbi Promegapoietin-1a, an engineered chimeric IL-3 and Mpl-L receptor agonist, stimulates hematopoietic recovery in conventional and abbreviated schedules following radiation-induced myelosuppression in nonhuman primates
    A M Farese
    Greenebaum Cancer Center, University of Maryland, Baltimore, Maryland 21201, USA
    Stem Cells 19:329-38. 2001
    ....
  6. ncbi Pegfilgrastim administered in an abbreviated schedule, significantly improved neutrophil recovery after high-dose radiation-induced myelosuppression in rhesus macaques
    A M Farese
    Department of Radiation Oncology, University of Maryland, School of Medicine, Baltimore, MD 21201, USA
    Radiat Res 178:403-13. 2012
    ....
  7. ncbi Pegfilgrastim, a sustained-duration form of filgrastim, significantly improves neutrophil recovery after autologous marrow transplantation in rhesus macaques
    A M Farese
    Greenebaum Cancer Center, University of Maryland, Baltimore, MD 21201, USA
    Bone Marrow Transplant 32:399-404. 2003
    ..Enhanced pharmacokinetics in AuBMT cohorts are consistent with self-regulating, neutrophil-mediated clearance...
  8. ncbi Defining the full therapeutic potential of recombinant growth factors in the post radiation-accident environment: the effect of supportive care plus administration of G-CSF
    Thomas J MacVittie
    Marlene and Stewart Greenebaum Cancer Center, Bressler Research Building, Room 7 039, University of Maryland Baltimore, 655 West Baltimore Street, Baltimore, MD 21201, USA
    Health Phys 89:546-55. 2005
    ..Clearly, the use of supportive care and G-CSF enhanced recovery of myelopoiesis and survival after lethal doses of irradiation...
  9. ncbi Polyclonal long-term MFGS-gp91phox marking in rhesus macaques after nonmyeloablative transplantation with transduced autologous peripheral blood progenitor cells
    Sebastian Brenner
    Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Mol Ther 14:202-11. 2006
    ..Some inserts landed in the vicinity of genes controlling cell cycle and proliferation. Statistical analyses of insertion sites 1 year posttransplant suggest a high diversity of insertion sites despite low marking...
  10. ncbi The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action
    Dirk E Smith
    Amgen Corporation, 51 University Street, Seattle, WA 98101, USA
    Immunity 18:87-96. 2003
    ..These findings suggest that the soluble form of IL-1R AcP contributes to the antagonism of IL-1 action by the type II decoy receptor, adding another layer of complexity to the regulation of IL-1 action...
  11. ncbi Increase in plasmacytoid and myeloid dendritic cells by progenipoietin-1, a chimeric Flt-3 and G-CSF receptor agonist, in SIV-Infected rhesus macaques
    Gerrit Koopman
    BPRC, Rijswijk, The Netherlands
    Hum Immunol 65:303-16. 2004
    ..In conclusion, ProGP-1 may be used to generate a transient increase in DC as well as CD4 T-cell numbers, thereby creating a window of opportunity for immunotherapeutic intervention...
  12. ncbi Systemic mobilization of antigen presenting cells, with a chimeric Flt-3 and G-CSF receptor agonist, during immunization of Macaca mulatta with HIV-1 antigens is insufficient to modulate immune responses or vaccine efficacy
    Gerrit Koopman
    Biomedical Primate Research Center, Department of Virology, Lange Kleiweg 139, 2288 GJ Rijswijk, The Netherlands
    Vaccine 23:4195-202. 2005
    ..We conclude that besides mobilization of dendritic cells additional stimuli to induce dendritic cell maturation may be needed for avid boosting of antigen specific immune activation...