Michael Fannon

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. ncbi Vitamin D binding protein-macrophage activating factor (DBP-maf) inhibits angiogenesis and tumor growth in mice
    Oliver Kisker
    Division of Surgical Research, Children's Hospital, Boston, MA 02115, USA
    Neoplasia 5:32-40. 2003
  2. ncbi Sucrose octasulfate regulates fibroblast growth factor-2 binding, transport, and activity: potential for regulation of tumor growth
    Michael Fannon
    Department of Ophthalmology and Visual Science, University of Kentucky, Lexington, Kentucky, USA
    J Cell Physiol 215:434-41. 2008
  3. ncbi Facilitated diffusion of VEGF165 through descemet's membrane with sucrose octasulfate
    Michael Fannon
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536 0305, USA
    J Cell Physiol 227:3693-700. 2012
  4. ncbi Endothelial cell capture of heparin-binding growth factors under flow
    Bing Zhao
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS Comput Biol 6:e1000971. 2010
  5. ncbi Vitamin D binding protein-macrophage activating factor directly inhibits proliferation, migration, and uPAR expression of prostate cancer cells
    Kalvin J Gregory
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS ONE 5:e13428. 2010
  6. ncbi Dose-dependent response of FGF-2 for lymphangiogenesis
    Lynn K Chang
    Vascular Biology Program, Department of Surgery, Children s Hospital Boston, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 101:11658-63. 2004
  7. ncbi PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition
    Dipak Panigrahy
    Vascular Biology Program, Children s Hospital, Department of Surgery, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:985-90. 2008
  8. ncbi Binding inhibition of angiogenic factors by heparan sulfate proteoglycans in aqueous humor: potential mechanism for maintenance of an avascular environment
    Michael Fannon
    Department of Surgery, The Children s Hospital, 300 Longwood Ave, Boston, Massachusetts 02115, USA
    FASEB J 17:902-4. 2003

Collaborators

  • Kimberly Forsten-Williams
  • Jun Zhang
  • Sami Dridi
  • Diane R Bielenberg
  • Dipak Panigrahy
  • Bing Zhao
  • Kalvin J Gregory
  • Steven Pirie-Shepherd
  • Lynn K Chang
  • Judah Folkman
  • Oliver Kisker
  • Jason Wu
  • Bin Huang
  • Weihua Jiang
  • Changjiang Zhang
  • Richard C Mulligan
  • Emy J Chen
  • Arja Kaipainen
  • Guillermo Garcia-Cardena
  • Catherine Butterfield
  • Marsha A Moses
  • Filip Farnebo
  • Bruce Zetter
  • Rahul Ray
  • Narasimha Swamy
  • Christian M Becker
  • Shinya Onizuka
  • Evelyn Flynn

Detail Information

Publications8

  1. ncbi Vitamin D binding protein-macrophage activating factor (DBP-maf) inhibits angiogenesis and tumor growth in mice
    Oliver Kisker
    Division of Surgical Research, Children's Hospital, Boston, MA 02115, USA
    Neoplasia 5:32-40. 2003
    ..Taken together, these data suggest that DBP-maf is an antiangiogenic molecule that can act directly on endothelium as well as stimulate macrophages to attack both the endothelial and tumor cell compartment of a growing malignancy...
  2. ncbi Sucrose octasulfate regulates fibroblast growth factor-2 binding, transport, and activity: potential for regulation of tumor growth
    Michael Fannon
    Department of Ophthalmology and Visual Science, University of Kentucky, Lexington, Kentucky, USA
    J Cell Physiol 215:434-41. 2008
    ..Our results suggest that molecules such as SOS have the potential to remove growth factors from tumor microenvironments and the approach offers an attractive area for further study...
  3. ncbi Facilitated diffusion of VEGF165 through descemet's membrane with sucrose octasulfate
    Michael Fannon
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536 0305, USA
    J Cell Physiol 227:3693-700. 2012
    ....
  4. ncbi Endothelial cell capture of heparin-binding growth factors under flow
    Bing Zhao
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS Comput Biol 6:e1000971. 2010
    ..The combined system offers opportunities to examine circulation capture in a straightforward quantitative manner that should prove advantageous for biologicals or drug delivery investigations...
  5. ncbi Vitamin D binding protein-macrophage activating factor directly inhibits proliferation, migration, and uPAR expression of prostate cancer cells
    Kalvin J Gregory
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS ONE 5:e13428. 2010
    ..Its activity, however, has been attributed to indirect mechanisms such as boosting the immune response by activating macrophages and inhibiting the blood vessel growth necessary for the growth of tumors...
  6. ncbi Dose-dependent response of FGF-2 for lymphangiogenesis
    Lynn K Chang
    Vascular Biology Program, Department of Surgery, Children s Hospital Boston, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 101:11658-63. 2004
    ..e., in the absence of angiogenesis, in the mouse cornea...
  7. ncbi PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition
    Dipak Panigrahy
    Vascular Biology Program, Children s Hospital, Department of Surgery, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:985-90. 2008
    ..Our results provide a mechanistic rationale for evaluating the clinical benefits of PPARalpha agonists in cancer treatment, alone and in combination with other therapies...
  8. ncbi Binding inhibition of angiogenic factors by heparan sulfate proteoglycans in aqueous humor: potential mechanism for maintenance of an avascular environment
    Michael Fannon
    Department of Surgery, The Children s Hospital, 300 Longwood Ave, Boston, Massachusetts 02115, USA
    FASEB J 17:902-4. 2003
    ..This mechanism suggests a physiological process to control bioavailability of angiogenic growth factors in the cornea...