Michael Fannon

Summary

Affiliation: University of Kentucky
Country: USA

Publications

  1. pmc Sucrose octasulfate regulates fibroblast growth factor-2 binding, transport, and activity: potential for regulation of tumor growth
    Michael Fannon
    Department of Ophthalmology and Visual Science, University of Kentucky, Lexington, Kentucky, USA
    J Cell Physiol 215:434-41. 2008
  2. pmc Vitamin D binding protein-macrophage activating factor (DBP-maf) inhibits angiogenesis and tumor growth in mice
    Oliver Kisker
    Division of Surgical Research, Children s Hospital, Boston, MA 02115, USA
    Neoplasia 5:32-40. 2003
  3. pmc Vitamin D binding protein-macrophage activating factor directly inhibits proliferation, migration, and uPAR expression of prostate cancer cells
    Kalvin J Gregory
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS ONE 5:e13428. 2010
  4. doi request reprint Facilitated diffusion of VEGF165 through descemet's membrane with sucrose octasulfate
    Michael Fannon
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536 0305, USA
    J Cell Physiol 227:3693-700. 2012
  5. pmc Endothelial cell capture of heparin-binding growth factors under flow
    Bing Zhao
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS Comput Biol 6:e1000971. 2010
  6. pmc Dose-dependent response of FGF-2 for lymphangiogenesis
    Lynn K Chang
    Vascular Biology Program, Department of Surgery, Children s Hospital Boston, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 101:11658-63. 2004
  7. pmc PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition
    Dipak Panigrahy
    Vascular Biology Program, Children s Hospital, Department of Surgery, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:985-90. 2008
  8. ncbi request reprint Binding inhibition of angiogenic factors by heparan sulfate proteoglycans in aqueous humor: potential mechanism for maintenance of an avascular environment
    Michael Fannon
    Department of Surgery, The Children s Hospital, 300 Longwood Ave, Boston, Massachusetts 02115, USA
    FASEB J 17:902-4. 2003

Collaborators

Detail Information

Publications8

  1. pmc Sucrose octasulfate regulates fibroblast growth factor-2 binding, transport, and activity: potential for regulation of tumor growth
    Michael Fannon
    Department of Ophthalmology and Visual Science, University of Kentucky, Lexington, Kentucky, USA
    J Cell Physiol 215:434-41. 2008
    ..Our results suggest that molecules such as SOS have the potential to remove growth factors from tumor microenvironments and the approach offers an attractive area for further study...
  2. pmc Vitamin D binding protein-macrophage activating factor (DBP-maf) inhibits angiogenesis and tumor growth in mice
    Oliver Kisker
    Division of Surgical Research, Children s Hospital, Boston, MA 02115, USA
    Neoplasia 5:32-40. 2003
    ..Taken together, these data suggest that DBP-maf is an antiangiogenic molecule that can act directly on endothelium as well as stimulate macrophages to attack both the endothelial and tumor cell compartment of a growing malignancy...
  3. pmc Vitamin D binding protein-macrophage activating factor directly inhibits proliferation, migration, and uPAR expression of prostate cancer cells
    Kalvin J Gregory
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS ONE 5:e13428. 2010
    ..Its activity, however, has been attributed to indirect mechanisms such as boosting the immune response by activating macrophages and inhibiting the blood vessel growth necessary for the growth of tumors...
  4. doi request reprint Facilitated diffusion of VEGF165 through descemet's membrane with sucrose octasulfate
    Michael Fannon
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, KY 40536 0305, USA
    J Cell Physiol 227:3693-700. 2012
    ....
  5. pmc Endothelial cell capture of heparin-binding growth factors under flow
    Bing Zhao
    Department of Ophthalmology and Visual Sciences, University of Kentucky, Lexington, Kentucky, United States of America
    PLoS Comput Biol 6:e1000971. 2010
    ..The combined system offers opportunities to examine circulation capture in a straightforward quantitative manner that should prove advantageous for biologicals or drug delivery investigations...
  6. pmc Dose-dependent response of FGF-2 for lymphangiogenesis
    Lynn K Chang
    Vascular Biology Program, Department of Surgery, Children s Hospital Boston, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 101:11658-63. 2004
    ..e., in the absence of angiogenesis, in the mouse cornea...
  7. pmc PPARalpha agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition
    Dipak Panigrahy
    Vascular Biology Program, Children s Hospital, Department of Surgery, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 105:985-90. 2008
    ..Our results provide a mechanistic rationale for evaluating the clinical benefits of PPARalpha agonists in cancer treatment, alone and in combination with other therapies...
  8. ncbi request reprint Binding inhibition of angiogenic factors by heparan sulfate proteoglycans in aqueous humor: potential mechanism for maintenance of an avascular environment
    Michael Fannon
    Department of Surgery, The Children s Hospital, 300 Longwood Ave, Boston, Massachusetts 02115, USA
    FASEB J 17:902-4. 2003
    ..This mechanism suggests a physiological process to control bioavailability of angiogenic growth factors in the cornea...