Yujiang Fang

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. pmc Murine FLIP transgene expressed on thyroid epithelial cells promotes resolution of granulomatous experimental autoimmune thyroiditis in DBA/1 mice
    Yujiang Fang
    Department of Internal Medicine, University of Missouri School of Medicine, and Veterans Affairs Research Service, Columbia, Missouri 65212, USA
    Am J Pathol 170:875-87. 2007
  2. doi request reprint A possible role for perforin and granzyme B in resveratrol-enhanced radiosensitivity of prostate cancer
    Yujiang Fang
    Department of Surgery, Ellis Fischel Cancer Center, University of Missouri School of Medicine, M316, Medical Sciences Building, Columbia, MO 65212, USA
    J Androl 33:752-60. 2012
  3. ncbi request reprint Hydrogen peroxide enhances radiation-induced apoptosis and inhibition of melanoma cell proliferation
    Yujiang Fang
    Department of Surgery, Ellis Fischel Cancer Center, University of Missouri School of Medicine, M316, Medical Sciences Building, Columbia, MO, 65212, USA
    Anticancer Res 33:1799-807. 2013
  4. doi request reprint A potential role for resveratrol as a radiation sensitizer for melanoma treatment
    Yujiang Fang
    Department of Surgery, University of Missouri School of Medicine, Columbia, MO 65212, USA
    J Surg Res 183:645-53. 2013
  5. doi request reprint Resveratrol enhances radiation sensitivity in prostate cancer by inhibiting cell proliferation and promoting cell senescence and apoptosis
    Yujiang Fang
    Department of Surgery, University of Missouri School of Medicine, Columbia, Missouri, USA
    Cancer Sci 103:1090-8. 2012
  6. pmc Cultured murine thyroid epithelial cells expressing transgenic Fas-associated death domain-like interleukin-1beta converting enzyme inhibitory protein are protected from fas-mediated apoptosis
    Yujiang Fang
    Division of Immunology and Rheumatology, Department of Medicine, University of Missouri, NE307 Medical Sciences, Columbia, MO 65212, USA
    Endocrinology 149:3321-9. 2008
  7. pmc Effect of transgenic overexpression of FLIP on lymphocytes on development and resolution of experimental autoimmune thyroiditis
    Yujiang Fang
    Department of Internal Medicine, University of Missouri School of Medicine, Columbia, Missouri, USA
    Am J Pathol 179:1211-20. 2011
  8. ncbi request reprint Expression of P-450(c11beta) in adrenal aldosterone-producing adenomas and nodular hyperplasia tissues
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Columbia, USA
    Clin Lab 57:245-51. 2011
  9. doi request reprint Sirtuin 1 in malignant transformation: friend or foe?
    Yujiang Fang
    Department of Surgery, University of Missouri School of Medicine, Columbia, 65212, USA
    Cancer Lett 306:10-4. 2011
  10. ncbi request reprint Modulation of apoptosis: new opportunities for drug discovery to treat autoimmune thyroiditis
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Missouri 65212, USA
    Recent Pat Inflamm Allergy Drug Discov 4:255-60. 2010

Collaborators

Detail Information

Publications26

  1. pmc Murine FLIP transgene expressed on thyroid epithelial cells promotes resolution of granulomatous experimental autoimmune thyroiditis in DBA/1 mice
    Yujiang Fang
    Department of Internal Medicine, University of Missouri School of Medicine, and Veterans Affairs Research Service, Columbia, Missouri 65212, USA
    Am J Pathol 170:875-87. 2007
    ..These results are consistent with the hypothesis that transgenic expression of FLIP on thyroid epithelial cells promotes earlier resolution of granulomatous experimental autoimmune thyroiditis...
  2. doi request reprint A possible role for perforin and granzyme B in resveratrol-enhanced radiosensitivity of prostate cancer
    Yujiang Fang
    Department of Surgery, Ellis Fischel Cancer Center, University of Missouri School of Medicine, M316, Medical Sciences Building, Columbia, MO 65212, USA
    J Androl 33:752-60. 2012
    ..These findings might be helpful in devising new strategies for treating PCA...
  3. ncbi request reprint Hydrogen peroxide enhances radiation-induced apoptosis and inhibition of melanoma cell proliferation
    Yujiang Fang
    Department of Surgery, Ellis Fischel Cancer Center, University of Missouri School of Medicine, M316, Medical Sciences Building, Columbia, MO, 65212, USA
    Anticancer Res 33:1799-807. 2013
    ..These data highlight the potential of H(2)O(2) as a radiation sensitizer for melanoma treatment and show that this warrants further study...
  4. doi request reprint A potential role for resveratrol as a radiation sensitizer for melanoma treatment
    Yujiang Fang
    Department of Surgery, University of Missouri School of Medicine, Columbia, MO 65212, USA
    J Surg Res 183:645-53. 2013
    ..Our group and others have previously shown that resveratrol (RSV) enhances radiation sensitivity in radioresistant prostate cancer cell lines...
  5. doi request reprint Resveratrol enhances radiation sensitivity in prostate cancer by inhibiting cell proliferation and promoting cell senescence and apoptosis
    Yujiang Fang
    Department of Surgery, University of Missouri School of Medicine, Columbia, Missouri, USA
    Cancer Sci 103:1090-8. 2012
    ..X, a marker for senescence. These data highlight the potential of RSV as a radiation sensitizer for PCA treatment and warrant further investigation...
  6. pmc Cultured murine thyroid epithelial cells expressing transgenic Fas-associated death domain-like interleukin-1beta converting enzyme inhibitory protein are protected from fas-mediated apoptosis
    Yujiang Fang
    Division of Immunology and Rheumatology, Department of Medicine, University of Missouri, NE307 Medical Sciences, Columbia, MO 65212, USA
    Endocrinology 149:3321-9. 2008
    ....
  7. pmc Effect of transgenic overexpression of FLIP on lymphocytes on development and resolution of experimental autoimmune thyroiditis
    Yujiang Fang
    Department of Internal Medicine, University of Missouri School of Medicine, Columbia, Missouri, USA
    Am J Pathol 179:1211-20. 2011
    ..These results suggest that effects of transgenic FLIP on a particular autoimmune disease vary, depending on what cells express the transgene and whether those cells are effector cells or if they function to modulate disease...
  8. ncbi request reprint Expression of P-450(c11beta) in adrenal aldosterone-producing adenomas and nodular hyperplasia tissues
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Columbia, USA
    Clin Lab 57:245-51. 2011
    ..This study was performed to further investigate if P-450(c11beta) contributes to the overproduction of aldosterone in APA and nodular hyperplasia tissues...
  9. doi request reprint Sirtuin 1 in malignant transformation: friend or foe?
    Yujiang Fang
    Department of Surgery, University of Missouri School of Medicine, Columbia, 65212, USA
    Cancer Lett 306:10-4. 2011
    ..Clearly, the role of SIRT1 in tumorigenesis is poorly understood and more research is necessary to elucidate its function in the malignant process...
  10. ncbi request reprint Modulation of apoptosis: new opportunities for drug discovery to treat autoimmune thyroiditis
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Missouri 65212, USA
    Recent Pat Inflamm Allergy Drug Discov 4:255-60. 2010
    ..Recent important patents focusing on apoptosis as novel therapeutic targets are also discussed in this review. Further clinical trials are needed to evaluate the efficacy and safety of these agents...
  11. ncbi request reprint Chemokines as novel therapeutic targets in autoimmune thyroiditis
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Columbia, MO 65212, USA
    Recent Pat DNA Gene Seq 4:52-7. 2010
    ..Recent patents which focus on chemokines as novel therapeutic targets in autoimmune thyroiditis were also discussed in this review. Such study might improve our knowledge about the roles of chemokines in autoimmune thyroiditis...
  12. doi request reprint Strategy for treating simple testicular cyst in adults
    Yujiang Fang
    University of Missouri, Columbia, MO 65211, USA
    Am J Mens Health 5:193-7. 2011
    ..Such a study may be helpful in managing a simple testicular cyst...
  13. doi request reprint A dispensable role for P450(scc) in the overproduction of aldosterone in aldosterone-producing adenoma and idiopathic hyperaldosteronism in patients with primary aldosteronism
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Columbia, MO 65211, USA
    Pathol Oncol Res 16:589-92. 2010
    ..05). These results suggest that P450(scc) contributes little to the overproduction of aldosterone in APA and IHA and cannot be considered as a marker to differentiate between them in patients with primary aldosteronism...
  14. pmc A critical role for TRAIL in resolution of granulomatous experimental autoimmune thyroiditis
    Y Fang
    Research Service, Harry S Truman Memorial VA Hospital, University of Missouri, Columbia, MO 65212, USA
    J Pathol 216:505-13. 2008
    ....
  15. pmc Eosinophils infiltrate thyroids, but have no apparent role in induction or resolution of experimental autoimmune thyroiditis in interferon-gamma(-/-) mice
    Yujiang Fang
    Department of Internal Medicine, University of Missouri School of Medicine, Columbia, MO, USA
    Immunology 129:329-37. 2010
    ....
  16. doi request reprint A critical role of surgery in the treatment for paraneoplastic pemphigus caused by localized Castleman's disease
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Columbia, MO, 65212, USA
    Med Oncol 27:907-11. 2010
    ..Most patients were followed up for 6-48 months, and they all had no clinical or radiological recurrence and remain disease free. Therefore, surgery is an effective approach to cure patients with PNP caused by localized CD...
  17. doi request reprint Escin improves sperm quality in male patients with varicocele-associated infertility
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Columbia, MO 65212, USA
    Phytomedicine 17:192-6. 2010
    ..To evaluate the efficacy of escin to improve sperm quality in Chinese male patients with varicocele-associated infertility...
  18. ncbi request reprint Expression of transgenic FLIP on thyroid epithelial cells inhibits induction and promotes resolution of granulomatous experimental autoimmune thyroiditis in CBA/J mice
    Yujiang Fang
    Division of Immunology and Rheumatology, Department of Medicine, University of Missouri, NE307 Medical Sciences, Columbia, MO 65212, USA
    Endocrinology 148:5734-45. 2007
    ..The results indicate that transgenic FLIP expressed on TECs in CBA/J mice promotes G-EAT resolution, but induction of G-EAT is inhibited unless CD8+ T cells are transiently depleted...
  19. pmc CD8+ T cells induce thyroid epithelial cell hyperplasia and fibrosis
    Shiguang Yu
    Department of Veterans Affairs Research Service, Columbia, MO 65212, USA
    J Immunol 186:2655-62. 2011
    ..This suggests that targeting CD8(+) T cells and/or TNF-α may be effective for treating epithelial cell hyperplasia and fibrosis...
  20. pmc Interleukin-10 promotes resolution of granulomatous experimental autoimmune thyroiditis
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Columbia, MO 65212, USA
    Am J Pathol 172:1591-602. 2008
    ..Further understanding of the mechanisms that promote the resolution of inflammation will facilitate the development of novel strategies for treating autoimmune diseases...
  21. pmc Transgenic expression of TGF-beta on thyrocytes inhibits development of spontaneous autoimmune thyroiditis and increases regulatory T cells in thyroids of NOD.H-2h4 mice
    Shiguang Yu
    Research Service, Department of Veterans Affairs, University of Missouri School of Medicine, Columbia, MO 65212, USA
    J Immunol 184:5352-9. 2010
    ..The results suggest that spontaneous autoimmune thyroiditis is inhibited in mice expressing transgenic TGF-beta on thyrocytes, at least in part, because there is an increased frequency of Tregs in their thyroids...
  22. pmc Comparison of sensitivity of Th1, Th2, and Th17 cells to Fas-mediated apoptosis
    Yujiang Fang
    Research Service, Harry S Truman Memorial VA Hospital, Department of Internal Medicine, School of Medicine, University of Missouri, Columbia, Missouri, USA
    J Leukoc Biol 87:1019-28. 2010
    ..Transgenic overexpression of FLIP in T cells protected all three subsets from Fas-mediated apoptosis. These findings provide new knowledge for understanding how survival of different subsets of T cells is regulated...
  23. pmc TGF-β promotes proliferation of thyroid epithelial cells in IFN-γ(-/-) mice by down-regulation of p21 and p27 via AKT pathway
    Yujiang Fang
    Department of Internal Medicine, School of Medicine, University of Missouri, Columbia, MO 65212, USA
    Am J Pathol 180:650-60. 2012
    ..H-2h4 mice, which may have significant implications for development of effective therapeutic strategies targeting the TGF-β and AKT pathways for treatment of hyperplasia and/or neoplasia...
  24. ncbi request reprint Contrasting roles of IFN-gamma in murine models of autoimmune thyroid diseases
    Yujiang Fang
    Department of Internal Medicine, University of Missouri, Columbia, Missouri, USA
    Thyroid 17:989-94. 2007
    ..H-2h4 mice and several different murine models of Graves' disease...
  25. pmc Agonistic anti-CD40 induces thyrocyte proliferation and promotes thyroid autoimmunity by increasing CD40 expression on thyroid epithelial cells
    Timothy Kayes
    Department of Internal Medicine, University of Missouri School of Medicine, Columbia, MO 65212, USA
    J Immunol 190:3928-38. 2013
    ..These studies provide new information regarding the role of target tissue expression of CD40 in development of autoimmunity and suggest that use of agonistic anti-CD40 for tumor therapy could result in autoimmune disease...
  26. ncbi request reprint A dual role for sirtuin 1 in tumorigenesis
    Yujiang Fang
    Department of Surgery, University of Missouri, One Hospital Drive, MC520E, DC116 94, Columbia, MO 65212, USA
    Curr Pharm Des 20:2634-6. 2014
    ..In this mini-review, we present the existing data which implicates SIRT1 in tumorigenesis. ..