Research Topics
| Margaret C FangSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Thirty-day mortality after ischemic stroke and intracranial hemorrhage in patients with atrial fibrillation on and off anticoagulantsMargaret C Fang
Department of Medicine, University of California, San Francisco, 505 Parnassus Avenue, Box 0131, San Francisco, CA 94143, USA
Stroke 43:1795-9. 2012..We assessed the impact of anticoagulation on 30-day mortality from ischemic stroke versus ICH in a large community-based cohort of patients with atrial fibrillation...
National trends in antiarrhythmic and antithrombotic medication use in atrial fibrillationMargaret C Fang
Massachusetts General Hospital, Boston, USA
Arch Intern Med 164:55-60. 2004..Atrial fibrillation is the most common cardiac arrhythmia associated with significant medical complications. We examined trends in the medical therapy of atrial fibrillation in the United States from 1991 through 2000...
Comparison of risk stratification schemes to predict thromboembolism in people with nonvalvular atrial fibrillationMargaret C Fang
Department of Medicine, University of California at San Francisco, San Francisco, California, USA
J Am Coll Cardiol 51:810-5. 2008..We assessed 5 risk stratification schemes for their ability to predict atrial fibrillation (AF)-related thromboembolism in a large community-based cohort...
Antithrombotic therapy for the treatment of atrial fibrillation in the elderlyMargaret C Fang
Division of Hospital Medicine, University of California at San Francisco, 533 Parnassus Ave, P O Box 0131, San Francisco, CA 94143, USA
J Interv Card Electrophysiol 25:19-23. 2009..Although the risk of intracranial hemorrhage is generally quite low, its occurrence is associated with significant mortality and disability, and more effective methods to risk stratify patients for intracranial hemorrhage are needed...
Language, literacy, and characterization of stroke among patients taking warfarin for stroke prevention: Implications for health communicationMargaret C Fang
Division of Hospital Medicine, University of California, San Francisco, CA 94143, United States
Patient Educ Couns 75:403-10. 2009..We assessed the stroke-related health literacy of anticoagulated patients to inform ways in which to improve health communication among people taking warfarin...
Trends in thrombolytic use for ischemic stroke in the United StatesMargaret C Fang
Division of Hospital Medicine, The University of California, San Francisco, San Francisco, California 94143, USA
J Hosp Med 5:406-9. 2010..Recent guidelines and regulatory agencies have advocated for increased tPA administration in appropriate patients, but it is unclear how many patients actually receive tPA...
Warfarin discontinuation after starting warfarin for atrial fibrillationMargaret C Fang
Department of Medicine, University of California, San Francisco, 94143, USA
Circ Cardiovasc Qual Outcomes 3:624-31. 2010..The objective of this study was to describe factors associated with warfarin discontinuation in patients newly starting warfarin for atrial fibrillation...
Use and outcomes of venous thromboembolism prophylaxis after spinal fusion surgeryM C Fang
Division of Hospital Medicine, The University of California San Francisco, CA, USA
J Thromb Haemost 9:1318-25. 2011..The number of spinal fusion operations in the USA is rapidly rising, but little is known about optimal venous thromboembolism prophylaxis after spinal surgery...
A new risk scheme to predict warfarin-associated hemorrhage: The ATRIA (Anticoagulation and Risk Factors in Atrial Fibrillation) StudyMargaret C Fang
Department of Medicine, University of California, San Francisco, San Francisco, California, USA
J Am Coll Cardiol 58:395-401. 2011..The purpose of this study was to develop a risk stratification score to predict warfarin-associated hemorrhage...
Death and disability from warfarin-associated intracranial and extracranial hemorrhagesMargaret C Fang
The Department of Medicine, Hospitalist Group, University of California, San Francisco, Calif 94143, USA
Am J Med 120:700-5. 2007..We examined the rates of death and disability resulting from warfarin-associated intracranial and extracranial hemorrhages in a large cohort of patients with atrial fibrillation...
Atrial fibrillation in the elderlyMargaret C Fang
Division of General Internal Medicine Hospitalist Group, University of California, San Francisco, CA 94143, USA
Am J Med 120:481-7. 2007..In symptomatic patients who fail pharmacologic therapy, invasive strategies such as AV nodal ablation may help improve quality of life and symptoms, although such strategies do not obviate the need for antithrombotic therapy...
Advanced age, anticoagulation intensity, and risk for intracranial hemorrhage among patients taking warfarin for atrial fibrillationMargaret C Fang
Division of General Internal Medicine, Hospitalist Group, University of California, San Francisco, San Francisco 94143, USA
Ann Intern Med 141:745-52. 2004..However, higher intensities increase hemorrhage risk. Optimal use of warfarin for atrial fibrillation requires precise information on the risk for intracranial hemorrhage as a function of patient age and anticoagulation intensity...
Are patients more likely to see physicians of the same sex? Recent national trends in primary care medicineMargaret C Fang
Division of General Internal Medicine Hospitalist Group, Department of Medicine, University of California, San Francisco, 94143, USA
Am J Med 117:575-81. 2004..We assessed national trends in the proportion of women among patients seeing female physicians, and compared visit characteristics and preventive services among visits to female and male primary care physicians...
Gender differences in the risk of ischemic stroke and peripheral embolism in atrial fibrillation: the AnTicoagulation and Risk factors In Atrial fibrillation (ATRIA) studyMargaret C Fang
University of California, San Francisco, CA 94143, USA
Circulation 112:1687-91. 2005..We examined data from a large contemporary cohort of AF patients to address this question...
Anticoagulation for atrial fibrillationMargaret C Fang
University of California, San Francisco, 533 Parnassus Avenue, Box 0131, San Francisco, CA 94143, USA
Cardiol Clin 22:47-62. 2004....
Health literacy and anticoagulation-related outcomes among patients taking warfarinMargaret C Fang
Division of General Internal Medicine, University of California at San Francisco, San Francisco, CA, USA
J Gen Intern Med 21:841-6. 2006..Little is known about whether health literacy affects anticoagulation-related outcomes...
Age and the risk of warfarin-associated hemorrhage: the anticoagulation and risk factors in atrial fibrillation studyMargaret C Fang
University of California at San Francisco, 94143, USA
J Am Geriatr Soc 54:1231-6. 2006..To assess whether older age is independently associated with hemorrhage risk in patients with atrial fibrillation, whether or not they are taking warfarin therapy...
Should patient characteristics influence target anticoagulation intensity for stroke prevention in nonvalvular atrial fibrillation?: the ATRIA studyDaniel E Singer
Clinical Epidemiology Unit, General Medicine Division, Massachusetts General Hospital, Boston, MA 02114, USA
Circ Cardiovasc Qual Outcomes 2:297-304. 2009..0 to 3.0 for preventing ischemic stroke in atrial fibrillation. We assessed whether the INR target should be adjusted based on selected patient characteristics...
The net clinical benefit of warfarin anticoagulation in atrial fibrillationDaniel E Singer
Massachusetts General Hospital, Boston, Massachussetts 02114, USA
Ann Intern Med 151:297-305. 2009..These guidelines rely on ischemic stroke rates observed in older trials and do not explicitly account for increased risk for hemorrhage...
Antithrombotic therapy in atrial fibrillation: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition)Daniel E Singer
Clinical Epidemiology Unit, Massachusetts General Hospital, Boston, MA 02114, USA
Chest 133:546S-592S. 2008..However, in patients without contraindications to anticoagulation, we suggest beginning IV heparin or LMWH at presentation (Grade 2C)...
Atrial fibrillation: stroke prevention in older adultsGene R Quinn
Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA
Clin Geriatr Med 28:617-34. 2012..For patients at lower stroke risk, bleeding risk stratification tools can also be used when the benefit of anticoagulant therapy is unclear...
Rates and predictors of plans for inferior vena cava filter retrieval in hospitalized patientsJohn F Mission
The University of California San Francisco School of Medicine, San Francisco, CA, USA
J Gen Intern Med 25:321-5. 2010..However, because of the increased risk of deep vein thrombosis with permanent filters, placement of retrievable filters has been recommended. Little is known about the factors associated with planned retrieval of IVC filters...
Performance of an online translation tool when applied to patient educational materialRaman R Khanna
Division of General Internal Medicine, University of California, San Francisco, San Francisco, California 94143 1211, USA
J Hosp Med 6:519-25. 2011..Online translation tools could fill this gap, but their accuracy is unknown. We evaluated the accuracy of an online translation tool for patient educational material...
Cost considerations surrounding current and future anticoagulant therapiesMargaret C Fang
Department of Medicine Hospitalist Group, University of California, San Francisco, CA 94143-0131, USA
Cleve Clin J Med 72:S43-9. 2005..These principles should guide clinicians' choices of anticoagulation strategies...
Trends in catheter ablation for atrial fibrillation in the United StatesPatrick P Kneeland
Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
J Hosp Med 4:E1-5. 2009..We analyzed data from the National Hospital Discharge Survey (NHDS) to examine trends in the rate of catheter ablation for hospitalized patients with AF over a 15-year period...
Current issues in patient adherence and persistence: focus on anticoagulants for the treatment and prevention of thromboembolismPatrick P Kneeland
The University of California, San Francisco Division of Hospital Medicine, San Francisco, CA, USA
Patient Prefer Adherence 4:51-60. 2010....
Antithrombotic therapy for stroke prevention in atrial fibrillationAlan S Go
Division of Research, Kaiser Permanente of Northern California, 2000 Broadway St, 3rd Floor, Oakland, CA 94612 2304, USA
Prog Cardiovasc Dis 48:108-24. 2005....
Research Grants
- Risks of Warfarin for Elders with Atrial FibrillationMargaret Fang; Fiscal Year: 2007..Together, these projects will provide practical experience and form the basis for future studies that seek to improve the safety and use of anticoagulants in the oldest patients with atrial fibrillation. ..
- Anticoagulation Treatment and Long-Term Outcomes After Venous ThromboembolismMargaret C Fang; Fiscal Year: 2010..This project will evaluate current treatment patterns for VTE, identify risk factors for adverse outcomes, and develop clinically applicable risk-stratification tools to help predict recurrent VTE and major hemorrhagic complications. ..
