Research Topics
| Xudong FanSummaryAffiliation: University of Missouri Country: USA Publications
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Detail Information
Publications
Sensitive optical biosensors for unlabeled targets: a reviewXudong Fan
Department of Biological Engineering, University of Missouri, 240D, Bond Life Sciences Center, 1201 E Rollins Street, Columbia, Missouri 65211, USA
Anal Chim Acta 620:8-26. 2008..Examples of detecting various types of biomolecules will be presented. Wherever possible, the sensing performance of each optical structure will be evaluated and compared in terms of sensitivity and detection limit...
Label-free detection with the liquid core optical ring resonator sensing platformIan M White
Biological Engineering Department, University of Missouri Columbia, Columbia, MO, USA
Methods Mol Biol 503:139-65. 2009..The LCORR is capable of performing refractive index detection on liquid samples, as well as bio/chemical analyte detection down to detection limits on the scale of pg/mm2 on a sensing surface...- Overview of the optofluidic ring resonator: a versatile platform for label-free biological and chemical sensingJonathan D Suter
Department of Biological Engineering, University of Missouri, Columbia, MO 65211, USA
Conf Proc IEEE Eng Med Biol Soc 2009:1042-4. 2009..Herein, we provide an overview of the basic operation principles of the OFRR and some examples of its most important applications, including the detection of proteins, virus, DNA molecules, whole cells, vapors and pesticides... 
Robust integrated optofluidic-ring-resonator dye lasersYuze Sun
Department of Biological Engineering, University of Missouri, Bond Life Sciences Center, Columbia, MO 65211, USA
Opt Lett 34:1042-4. 2009..Laser oscillation is achieved with a threshold of 7 microJ/mm2 per pulse. Furthermore, the laser emission can be directionally outcoupled through a fiber prism for easy and efficient light delivery...- Analysis of ring resonators for chemical vapor sensor developmentYuze Sun
Department of Biological Engineering, University of Missouri, 240D Bond Life Sciences Center, 1201 E Rollins Street, Columbia, MO 65211, USA
Opt Express 16:10254-68. 2008..Similarities and differences between the two sensor configurations are also discussed. Our work should provide a general guidance in development of sensitive ring resonator chemical vapor sensors... - Label-free quantitative DNA detection using the liquid core optical ring resonatorJonathan D Suter
Department of Biological Engineering, 240D Bond Life Sciences Center, University of Missouri Columbia, Columbia, MO 65211, USA
Biosens Bioelectron 23:1003-9. 2008..Our work will provide important insight into the light-DNA interaction at the ring resonator surface and lay a foundation for future LCORR-based DNA label-free microarray development... - Opto-fluidic micro-ring resonator for sensitive label-free viral detectionHongying Zhu
Department of Biological Engineering, University of Missouri Columbia, 240D, Bond Life Sciences Center, Columbia, MO 65211, USA
Analyst 133:356-60. 2008..Theoretical analysis was also carried out to confirm the experimental results. Our study will lead to development of novel OFRR-based, sensitive, rapid, and low-cost micro total analysis devices for virus detection... - On the performance quantification of resonant refractive index sensorsIan M White
Biological Engineering Department, University of Missouri Columbia, 240D Bond Life Sciences Center, 1201 E Rollins Street, Columbia, MO 65211, USA
Opt Express 16:1020-8. 2008..Our work will enable a standard approach for quantifying and comparing the performance of optical resonance-based RI sensors. Additionally, it will lead to design strategies for performance improvement of RI sensors... - Rapid tandem-column micro-gas chromatography based on optofluidic ring resonators with multi-point on-column detectionYuze Sun
Department of Biological Engineering 240D Bond Life Sciences Center, University of Missouri, 1201 E Rollins Street, Columbia, Missouri 65211, USA
Analyst 135:165-71. 2010..Our results will lead to the development of a rapid, simple, and portable microGC system with significantly improved selectivity and chemical identification capabilities... - Thermal characterization of liquid core optical ring resonator sensorsJonathan D Suter
Department of Biological Engineering, University of Missouri Columbia, Mossouri 6521, USA
Appl Opt 46:389-96. 2007..Theoretical calculations based on Mie theory are used to verify the experimental observations... - Label-free analysis of DNA methylation using optofluidic ring resonatorsJonathan D Suter
Department of Biological Engineering, University of Missouri, Columbia, MO 65211, USA
Conf Proc IEEE Eng Med Biol Soc 2009:2760-2. 2009..Such behavior is suspected to be strongly related to the occurrence of several types of cancers. The OFRR is demonstrated as a tool both for detecting DNA hybridization and methylated cytosines residues... - Highly versatile fiber-based optical Fabry-Pérot gas sensorJing Liu
Biological Engineering Department, University of Missouri, 240D Bond Life Sciences Center, 1201 E Rollins Street, Columbia, Missouri 65211, USA
Opt Express 17:2731-8. 2009..5 pm/ppm and 0.1 pm/ppm for PEG 400 and NOA 81, respectively, with a detection limit on the order of 1-10 ppm. Gas sensing for the analytes delivered in both continuous flow mode and pulsed mode is demonstrated... - Integrated refractive index optical ring resonator detector for capillary electrophoresisHongying Zhu
Department of Biological Engineering, 240D Life Sciences Center, University of Missouri Columbia, Columbia, Missouri 65211, USA
Anal Chem 79:930-7. 2007..The investigation in this regard will open a door to novel high-throughput CE devices and lab-on-a-chip sensors in the future... - PDMS embedded opto-fluidic microring resonator lasersJonathan D Suter
Biological Engineering Department, 240D Bond Life Sciences Center, University of Missouri, Columbia, MO 65211, USA
Opt Express 16:10248-53. 2008..2 microJ/mm(2) pump intensity, the laser output from the fiber prism is 80 nW, corresponding to 50% power extraction efficiency. A microarray structure of parallel OFRRs is also demonstrated, allowing simultaneous multi-color emissions... - Phage-based label-free biomolecule detection in an opto-fluidic ring resonatorHongying Zhu
Department of Biological Engineering, University of Missouri, 240D Bond Life Sciences Center, Columbia, MO 65211, United States
Biosens Bioelectron 24:461-6. 2008..The phage-based OFRR biosensor will become a promising platform for universal biomolecule detection with high sensitivity, low cost, and good reusability... - Label free detection of CD4+ and CD8+ T cells using the optofluidic ring resonatorJohn T Gohring
Department of Biological Engineering, 240D Bond Life Sciences Center, 1201 East Rollins Street, University of Missouri, Columbia, MO 65211, USA
Sensors (Basel) 10:5798-808. 2010..This work will lead to a rapid and low-cost sensing device that can provide a CD4 and CD8 count as a measure of HIV progression... - Rapid and label-free detection of breast cancer biomarker CA15-3 in clinical human serum samples with optofluidic ring resonator sensorsHongying Zhu
Department of Biological Engineering, University of Missouri, 240D Bond Life Sciences Center, Columbia, Missouri 65211, USA
Anal Chem 81:9858-65. 2009..Our work marks the first demonstration of the optical ring resonator biosensor in real clinical applications that features low cost, simple detection procedures, rapid response time, low sample consumption, and high specificity... - Detection of Escherichia coli O157:H7 and Salmonella in ground beef by a bead-free quantum dot-facilitated isolation methodLuxin Wang
Food Science Program, Division of Food Systems and Bioengineering, 256 WCS Wing, Eckles Hall, University of Missouri, Columbia, MO 65211, USA
Int J Food Microbiol 156:83-7. 2012..To our knowledge, this detection method is the first research that combined a new EDC-protein A QD-labeling technique and bead-free fluorescence measurement to detect E. coli O157:H7 and Salmonella in ground beef... - Compact quantum dot probes for rapid and sensitive DNA detection using highly efficient fluorescence resonant energy transferChung Shieh Wu
Biological Engineering Department, University of Missouri, 240D Bond Life Sciences Center, 1201 E Rollins Street, Columbia, MO 65211, USA
Nanotechnology 20:305502. 2009..Theoretical analysis was also performed to confirm our results... - Optofluidic ring resonator sensors for rapid DNT vapor detectionYuze Sun
Department of Biological Engineering, 240D Bond Life Sciences Center, University of Missouri, 1201 E Rollins Street, Columbia, Missouri 65211, USA
Analyst 134:1386-91. 2009..Our study shows that the OFRR vapor sensor is a promising platform for the development of a rapid, low-cost, and portable analytical device for explosive detection and monitoring... - Liquid-core optical ring-resonator sensorsIan M White
Department of Biological Engineering, University of Missouri-Columbia, Missouri 65211, USA
Opt Lett 31:1319-21. 2006.... - Subfemtomole detection of small molecules with microsphere sensorsIan M White
Department of Biological Engineering, University of Missouri-Columbia, Missouri 65211, USA
Opt Lett 30:3189-91. 2005..01 layer of silica) decrease in sphere radius, corresponding to a change of 0.4 fmol silica molecule. These results suggest that small molecules can be detected in trace quantities at the surface of an optical microsphere sensor... - Optical leaky waveguide biosensors for the detection of organophosphorus pesticidesM Zourob
School of Chemical Engineering and Analytical Science, University of Manchester, Manchester, UK
Analyst 132:114-20. 2007..The platforms developed in this work were successfully used to detect paraoxon and parathion down to 4 nM concentrations...