Xiaobing Fan

..This study provides useful information to better understand the limitations and safety concerns of performing MR-HIFU treatments with commercial clinical equipment...

..Specifically, fitting the data with the empirical model showed that metastatic tumors had significantly faster contrast media uptake (p<0.001) and slower washout rates (p<0.01) than non-metastatic tumors...

..In summary, the present research suggests that the EMM is a promising alternative method for evaluating DCE-MRI data with improved diagnostic accuracy...

..HiSS allowed detection of lesions and evaluation of lesion morphology prior to contrast media injection. J. Magn. Reson. Imaging 2006. (c) 2006 Wiley-Liss, Inc...

..83. In the human breast, an inhomogeneously broadened water resonance can serve as a correlate marker for malignancy and is likely to reflect the underlying anatomy or physiology...

..In addition, a comparison of the dynamics of Gd-DTPA and P792 provides information regarding the microenvironment of tumors...

..These results suggest that tumor microvasculature can be detected using HiSS imaging without the use of contrast agents...

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..To compare the pathology and kinetic characteristics of breast lesions with focus-, mass-, and nonmass-like enhancement...

..PFC droplets may allow practical and quantitative measurements of blood volume and capillary permeability in tumours with reasonable spatial resolution...

..There was no significant difference in the distributions of K(trans) and v(e) between control and treated rats. The results showed that no effects of green tea on tumor micro-vasculature were measurable by dynamic Gd-DTPA enhanced MRI...

..To evaluate the effect of varying spectral resolution on image quality of high spectral and spatial resolution (HiSS) images...

..The synthesis of water Fourier component images from high spectral and spatial resolution data may provide a new form of contrast, and increase sensitivity to subvoxel physiology and anatomy...

..To determine relative diagnostic value of MR diffusion and perfusion parameters in detection of active small bowel inflammation in patients with Crohn's disease (CD)...

..0005). The results demonstrate that both T(2)-weighted anatomic imaging and quantitative analysis of dynamic contrast-enhanced MRI data can successfully distinguish colitis from normal colon in mice...

..This suggests that the EMM may be useful for analysis of routine clinical data...

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..Values obtained for K(trans) and v(e) in muscle, and the shape and amplitude of the derived arterial input function are consistent with published results...

..To evaluate feasibility of high-resolution, high-field ex vivo prostate magnetic resonance imaging (MRI) as an aid to guide pathologists' examination and develop in vivo MRI methods...

..To quantify the relationship between dose of contrast administered and contrast kinetics of malignant breast lesions...

..The purpose of this study was to compare MRI kinetic curve data acquired with three systems in the evaluation of malignant lesions of the breast...

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..The aim of this study was to evaluate the feasibility of quantitative analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data in the detection of bowel inflammation in patients with Crohn's disease...

..If the results of this pilot study are validated in a larger trial, we expect that to maximize diagnostic utility, it will be better to classify lesion morphology as mass or nonmass-like enhancement prior to kinetic analysis...

..Response to hyperthermia measured by MRI may be useful for identifying and/or characterizing suspicious lesions as well as guiding the development of new hyperthermia protocols...

..g., caused by hemosiderin or deoxyhemoglobin. In these mouse models, unlike in patients, the characteristics of single mammary ducts containing pure intraductal cancer can be evaluated...

..In hypoxic regions where increases in pO(2) are most desirable, carbogen was ineffective. The data suggest that (19)F and (1)H MRI can be used individually or in combination to guide the design of improved tumor-oxygenating agents...

..This technique is most useful in conjunction with high-resolution EPSI of water and fat resonances, but is less applicable to EPSI of metabolites due to the complexity of the spectra...

..This present study demonstrates that MRI is an excellent candidate for performing longitudinal assessment of early stage mammary cancer disease progression and response to therapy in the transgenic model system...

..The purpose of this study was to use magnetic resonance (MR) imaging to track in vivo the transition from in situ neoplasia to invasive cancer in a transgenic mouse model of human cancer...

..In this article, we are going to review the analysis techniques of dynamic contrast-enhanced MRI and its various clinical applications in prostate cancer patients...

..These preliminary results suggest that HiSS MRI provides detailed morphology of the murine prostate and can detect early changes associated with the development of cancer. HiSS MRI of patients may have similar advantages...

..The data demonstrate a strong correlation between tumor vasculature identified using HiSS and two gold standards: histology and microCT angiography...

..HSSR MR imaging data acquired before and after contrast medium injection showed spectrally inhomogeneous changes in the water resonances in small voxels that were not detectable with conventional MR imaging...

..025). This is the first report of minimally invasive, quantitative, absolute oxygen measurements correlated with tissue perfusion in vivo...

..0 × 10(-3) mm²/s (Az value 1.0). DW-MRI is a valuable adjunct to T2-weighted images diagnosing abdominopelvic abscesses. ADC measurements may have the potential to differentiate abdominal abscesses from ascites...

..In addition, "impulse response analysis" leads to the derivation of novel parameters relating to tumor vascular architecture, and these new parameters may have clinical utility...

..HiSS imaging of brain provides accurate anatomic information, and may improve image contrast and delineation of subtle anatomic features...

..The open birdcage coil offers easy access and better quality mouse cardiac imaging than both the single loop surface coil and volume birdcage coil and does not require extensive RF engineering expertise to construct...

..The spectrally inhomogeneous effects of tumor oxygenating agents may reflect changes in sub-voxelar microenvironements and thus may be important for accurate evaluation of the effects of therapy...

..In this article, the MR imaging features of TZ prostate cancers, the role of MR imaging in TZ cancer detection and staging, and recent advanced MR techniques will be discussed in light of the literature...