Xiaobing Fan

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. doi Safety limitations of MR-HIFU treatment near interfaces: a phantom validation
    Elizabeth Hipp
    Department of Radiology, MC2026 University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    J Appl Clin Med Phys 13:3739. 2012
  2. ncbi Multi-slice DCE-MRI data using P760 distinguishes between metastatic and non-metastatic rodent prostate tumors
    Xiaobing Fan
    Department of Radiology, University of Chicago, IL 60637, USA
    MAGMA 19:15-21. 2006
  3. pmc Diagnosis of suspicious breast lesions using an empirical mathematical model for dynamic contrast-enhanced MRI
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Magn Reson Imaging 25:593-603. 2007
  4. ncbi Fat suppression with spectrally selective inversion vs. high spectral and spatial resolution MRI of breast lesions: qualitative and quantitative comparisons
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    J Magn Reson Imaging 24:1311-5. 2006
  5. pmc Sensitivity to tumor microvasculature without contrast agents in high spectral and spatial resolution MR images
    Sean Foxley
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 61:291-8. 2009
  6. pmc Fourier component imaging of water resonance in the human breast provides markers for malignancy
    Milica Medved
    Department of Radiology, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Phys Med Biol 54:5767-79. 2009
  7. ncbi New model for analysis of dynamic contrast-enhanced MRI data distinguishes metastatic from nonmetastatic transplanted rodent prostate tumors
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 51:487-94. 2004
  8. ncbi Comparison of high-resolution echo-planar spectroscopic imaging with conventional MR imaging of prostate tumors in mice
    Weiliang Du
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    NMR Biomed 18:285-92. 2005
  9. pmc Non-contrast enhanced MRI for evaluation of breast lesions: comparison of non-contrast enhanced high spectral and spatial resolution (HiSS) images versus contrast enhanced fat-suppressed images
    Milica Medved
    Department of Radiology, MC2026, 5841 S Maryland Avenue, University of Chicago, Chicago, IL 60637, USA
    Acad Radiol 18:1467-74. 2011
  10. ncbi MRI of perfluorocarbon emulsion kinetics in rodent mammary tumours
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Phys Med Biol 51:211-20. 2006

Detail Information

Publications44

  1. doi Safety limitations of MR-HIFU treatment near interfaces: a phantom validation
    Elizabeth Hipp
    Department of Radiology, MC2026 University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    J Appl Clin Med Phys 13:3739. 2012
    ..This study provides useful information to better understand the limitations and safety concerns of performing MR-HIFU treatments with commercial clinical equipment...
  2. ncbi Multi-slice DCE-MRI data using P760 distinguishes between metastatic and non-metastatic rodent prostate tumors
    Xiaobing Fan
    Department of Radiology, University of Chicago, IL 60637, USA
    MAGMA 19:15-21. 2006
    ..Specifically, fitting the data with the empirical model showed that metastatic tumors had significantly faster contrast media uptake (p<0.001) and slower washout rates (p<0.01) than non-metastatic tumors...
  3. pmc Diagnosis of suspicious breast lesions using an empirical mathematical model for dynamic contrast-enhanced MRI
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Magn Reson Imaging 25:593-603. 2007
    ..In summary, the present research suggests that the EMM is a promising alternative method for evaluating DCE-MRI data with improved diagnostic accuracy...
  4. ncbi Fat suppression with spectrally selective inversion vs. high spectral and spatial resolution MRI of breast lesions: qualitative and quantitative comparisons
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    J Magn Reson Imaging 24:1311-5. 2006
    ..To compare conventional fat-suppressed MR images of the breast to images derived from high spectral and spatial resolution MR data. Image quality and the level of fat suppression are compared qualitatively and quantitatively...
  5. pmc Sensitivity to tumor microvasculature without contrast agents in high spectral and spatial resolution MR images
    Sean Foxley
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 61:291-8. 2009
    ..These results suggest that tumor microvasculature can be detected using HiSS imaging without the use of contrast agents...
  6. pmc Fourier component imaging of water resonance in the human breast provides markers for malignancy
    Milica Medved
    Department of Radiology, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Phys Med Biol 54:5767-79. 2009
    ..83. In the human breast, an inhomogeneously broadened water resonance can serve as a correlate marker for malignancy and is likely to reflect the underlying anatomy or physiology...
  7. ncbi New model for analysis of dynamic contrast-enhanced MRI data distinguishes metastatic from nonmetastatic transplanted rodent prostate tumors
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 51:487-94. 2004
    ..In addition, a comparison of the dynamics of Gd-DTPA and P792 provides information regarding the microenvironment of tumors...
  8. ncbi Comparison of high-resolution echo-planar spectroscopic imaging with conventional MR imaging of prostate tumors in mice
    Weiliang Du
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    NMR Biomed 18:285-92. 2005
    ....
  9. pmc Non-contrast enhanced MRI for evaluation of breast lesions: comparison of non-contrast enhanced high spectral and spatial resolution (HiSS) images versus contrast enhanced fat-suppressed images
    Milica Medved
    Department of Radiology, MC2026, 5841 S Maryland Avenue, University of Chicago, Chicago, IL 60637, USA
    Acad Radiol 18:1467-74. 2011
    ....
  10. ncbi MRI of perfluorocarbon emulsion kinetics in rodent mammary tumours
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Phys Med Biol 51:211-20. 2006
    ..PFC droplets may allow practical and quantitative measurements of blood volume and capillary permeability in tumours with reasonable spatial resolution...
  11. ncbi Fourier components of inhomogeneously broadened water resonances in breast: a new source of MRI contrast
    Milica Medved
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 52:193-6. 2004
    ..The synthesis of water Fourier component images from high spectral and spatial resolution data may provide a new form of contrast, and increase sensitivity to subvoxel physiology and anatomy...
  12. ncbi The effect of varying spectral resolution on the quality of high spectral and spatial resolution magnetic resonance images of the breast
    Milica Medved
    Department of Radiology, The University of Chicago, Chicago, Illinois 60637, USA
    J Magn Reson Imaging 18:442-8. 2003
    ..To evaluate the effect of varying spectral resolution on image quality of high spectral and spatial resolution (HiSS) images...
  13. pmc The diverse pathology and kinetics of mass, nonmass, and focus enhancement on MR imaging of the breast
    Sanaz A Jansen
    Department of Radiology, The University of Chicago, Chicago, Illinois 60637, USA
    J Magn Reson Imaging 33:1382-9. 2011
    ..To compare the pathology and kinetic characteristics of breast lesions with focus-, mass-, and nonmass-like enhancement...
  14. doi Can DCEMRI assess the effect of green tea on the angiogenic properties of rodent prostate tumors?
    Xiaobing Fan
    Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
    Phys Med 26:111-6. 2010
    ..There was no significant difference in the distributions of K(trans) and v(e) between control and treated rats. The results showed that no effects of green tea on tumor micro-vasculature were measurable by dynamic Gd-DTPA enhanced MRI...
  15. pmc Use of a reference tissue and blood vessel to measure the arterial input function in DCEMRI
    Xiaobing Fan
    Department of Radiology, The University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 64:1821-6. 2010
    ..Values obtained for K(trans) and v(e) in muscle, and the shape and amplitude of the derived arterial input function are consistent with published results...
  16. pmc High-resolution magnetic resonance colonography and dynamic contrast-enhanced magnetic resonance imaging in a murine model of colitis
    Devkumar Mustafi
    Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois, USA
    Magn Reson Med 63:922-9. 2010
    ..0005). The results demonstrate that both T(2)-weighted anatomic imaging and quantitative analysis of dynamic contrast-enhanced MRI data can successfully distinguish colitis from normal colon in mice...
  17. pmc Differentiation between benign and malignant breast lesions detected by bilateral dynamic contrast-enhanced MRI: a sensitivity and specificity study
    Sanaz A Jansen
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 59:747-54. 2008
    ..This suggests that the EMM may be useful for analysis of routine clinical data...
  18. doi Active Crohn's disease in the small bowel: evaluation by diffusion weighted imaging and quantitative dynamic contrast enhanced MR imaging
    Aytekin Oto
    Department of Radiology, The University of Chicago, Chicago, Illinois, USA
    J Magn Reson Imaging 33:615-24. 2011
    ..To determine relative diagnostic value of MR diffusion and perfusion parameters in detection of active small bowel inflammation in patients with Crohn's disease (CD)...
  19. pmc T(2)∗ relaxation times of intraductal murine mammary cancer, invasive mammary cancer, and normal mammary gland
    Elizabeth Hipp
    Department of Radiology, University of Chicago, Chicago, IL, USA
    Med Phys 39:1309-13. 2012
    ..g., caused by hemosiderin or deoxyhemoglobin. In these mouse models, unlike in patients, the characteristics of single mammary ducts containing pure intraductal cancer can be evaluated...
  20. doi High-resolution MRI of excised human prostate specimens acquired with 9.4T in detection and identification of cancers: validation of a technique
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    J Magn Reson Imaging 34:956-61. 2011
    ..To evaluate feasibility of high-resolution, high-field ex vivo prostate magnetic resonance imaging (MRI) as an aid to guide pathologists' examination and develop in vivo MRI methods...
  21. doi Relating dose of contrast media administered to uptake and washout of malignant lesions on DCEMRI of the breast
    Sanaz A Jansen
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Acad Radiol 17:24-30. 2010
    ..To quantify the relationship between dose of contrast administered and contrast kinetics of malignant breast lesions...
  22. doi Quantitative analysis of dynamic contrast enhanced MRI for assessment of bowel inflammation in Crohn's disease pilot study
    Aytekin Oto
    Department of Radiology, University of Chicago, 5841 S Maryland Avenue, MC 2026, Chicago, IL 60637, USA
    Acad Radiol 16:1223-30. 2009
    ..The aim of this study was to evaluate the feasibility of quantitative analysis of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data in the detection of bowel inflammation in patients with Crohn's disease...
  23. pmc DCEMRI of breast lesions: is kinetic analysis equally effective for both mass and nonmass-like enhancement?
    Sanaz A Jansen
    Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, MC2026, Chicago, Illinois 60637, USA
    Med Phys 35:3102-9. 2008
    ..If the results of this pilot study are validated in a larger trial, we expect that to maximize diagnostic utility, it will be better to classify lesion morphology as mass or nonmass-like enhancement prior to kinetic analysis...
  24. pmc Kinetic curves of malignant lesions are not consistent across MRI systems: need for improved standardization of breast dynamic contrast-enhanced MRI acquisition
    Sanaz A Jansen
    Department of Radiology, University of Chicago, 5841 S Maryland Ave, MC 2026, Chicago, IL 60637, USA
    AJR Am J Roentgenol 193:832-9. 2009
    ..The purpose of this study was to compare MRI kinetic curve data acquired with three systems in the evaluation of malignant lesions of the breast...
  25. pmc Ductal carcinoma in situ: X-ray fluorescence microscopy and dynamic contrast-enhanced MR imaging reveals gadolinium uptake within neoplastic mammary ducts in a murine model
    Sanaz A Jansen
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Radiology 253:399-406. 2009
    ....
  26. pmc Hyperthermically induced changes in high spectral and spatial resolution MR images of tumor tissue--a pilot study
    Sean Foxley
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Phys Med Biol 57:2653-66. 2012
    ..Response to hyperthermia measured by MRI may be useful for identifying and/or characterizing suspicious lesions as well as guiding the development of new hyperthermia protocols...
  27. ncbi Effect of carbogen on tumor oxygenation: combined fluorine-19 and proton MRI measurements
    Xiaobing Fan
    Department of Radiology, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Int J Radiat Oncol Biol Phys 54:1202-9. 2002
    ..19)F and (1)H measurements were used to classify pixels as responders to carbogen (pixels where oxygen increased significantly) or nonresponders (no significant change in tumor oxygenation)...
  28. ncbi In vivo MRI of early stage mammary cancers and the normal mouse mammary gland
    Sanaz A Jansen
    Department of Radiology, University of Chicago, Chicago, IL, USA
    NMR Biomed 24:880-7. 2011
    ..This present study demonstrates that MRI is an excellent candidate for performing longitudinal assessment of early stage mammary cancer disease progression and response to therapy in the transgenic model system...
  29. ncbi Reduction of spectral ghost artifacts in high-resolution echo-planar spectroscopic imaging of water and fat resonances
    Weiliang Du
    Department of Radiology, University of Chicago, Illinois 60637, USA
    Magn Reson Med 49:1113-20. 2003
    ..This technique is most useful in conjunction with high-resolution EPSI of water and fat resonances, but is less applicable to EPSI of metabolites due to the complexity of the spectra...
  30. doi Comparing post-operative human breast specimen radiograph and MRI in lesion margin and volume assessment
    Hiroyuki Abe
    Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
    J Appl Clin Med Phys 13:3802. 2012
    ..However, there are technical challenges in visualization of DCIS lesions. Improvements in specimen imaging are important, as they will provide additional information to standard radiographic analysis...
  31. pmc Magnetic resonance imaging of the natural history of in situ mammary neoplasia in transgenic mice: a pilot study
    Sanaz A Jansen
    Department of Radiology, University of Chicago, 5841 South Maryland Avenue, MC 2026, Chicago IL 60637, USA
    Breast Cancer Res 11:R65. 2009
    ..The purpose of this study was to use magnetic resonance (MR) imaging to track in vivo the transition from in situ neoplasia to invasive cancer in a transgenic mouse model of human cancer...
  32. ncbi Breast MR imaging with high spectral and spatial resolutions: preliminary experience
    Weiliang Du
    Department of Radiology, MC2026, University of Chicago, 5841 S Maryland Ave, Chicago, IL 60637, USA
    Radiology 224:577-85. 2002
    ..HSSR MR imaging data acquired before and after contrast medium injection showed spectrally inhomogeneous changes in the water resonances in small voxels that were not detectable with conventional MR imaging...
  33. pmc HiSStology: high spectral and spatial resolution magnetic resonance imaging detection of vasculature validated by histology and micro-computed tomography
    Chad R Haney
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Mol Imaging 10:187-96. 2011
    ..The data demonstrate a strong correlation between tumor vasculature identified using HiSS and two gold standards: histology and microCT angiography...
  34. pmc Characterization of response to radiation mediated gene therapy by means of multimodality imaging
    Chad R Haney
    University of Chicago, Department of Radiology, Chicago, IL 60637 1463, USA
    Magn Reson Med 62:348-56. 2009
    ..025). This is the first report of minimally invasive, quantitative, absolute oxygen measurements correlated with tissue perfusion in vivo...
  35. doi High spectral and spatial resolution MRI of age-related changes in murine prostate
    Sean Foxley
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    Magn Reson Med 60:575-81. 2008
    ..These preliminary results suggest that HiSS MRI provides detailed morphology of the murine prostate and can detect early changes associated with the development of cancer. HiSS MRI of patients may have similar advantages...
  36. doi Dynamic contrast-enhanced magnetic resonance imaging in prostate cancer
    Arda Kayhan
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Top Magn Reson Imaging 20:105-12. 2009
    ..In this article, we are going to review the analysis techniques of dynamic contrast-enhanced MRI and its various clinical applications in prostate cancer patients...
  37. doi Diffusion-weighted MR imaging of abdominopelvic abscesses
    Aytekin Oto
    Department of Radiology, University of Chicago, 5841 S Maryland Avenue, MC 2026, Chicago, IL 60637, USA
    Emerg Radiol 18:515-24. 2011
    ..0 × 10(-3) mm²/s (Az value 1.0). DW-MRI is a valuable adjunct to T2-weighted images diagnosing abdominopelvic abscesses. ADC measurements may have the potential to differentiate abdominal abscesses from ascites...
  38. pmc A new approach to analysis of the impulse response function (IRF) in dynamic contrast-enhanced MRI (DCEMRI): a simulation study
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Magn Reson Med 62:229-39. 2009
    ..In addition, "impulse response analysis" leads to the derivation of novel parameters relating to tumor vascular architecture, and these new parameters may have clinical utility...
  39. pmc Empirical mathematical model for dynamic manganese-enhanced MRI of the murine pancreas for assessment of β-cell function
    Anita H Dhyani
    Department of Radiology, MC2026, University of Chicago, Chicago, IL 60637, USA
    Magn Reson Imaging 31:508-14. 2013
    ..Dynamic MEMRI is a promising technique for assessing β-cell functionality and vascular perfusion with potential applications for monitoring diabetes progression and/or therapy...
  40. ncbi Structure of the water resonance in small voxels in rat brain detected with high spectral and spatial resolution MRI
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, Illinois 60637, USA
    J Magn Reson Imaging 16:547-52. 2002
    ..To acquire high spectral and spatial resolution (HiSS) MR images of the water resonance in rat brain, evaluate the lineshape of the water resonance in small voxels, and compare images derived from HiSS data with conventional images...
  41. ncbi MRI of neonatal necrotizing enterocolitis in a rodent model
    Devkumar Mustafi
    Department of Radiology, University of Chicago, Chicago, IL, USA
    NMR Biomed 27:272-9. 2014
    ....
  42. ncbi Comparison and evaluation of mouse cardiac MRI acquired with open birdcage, single loop surface and volume birdcage coils
    Xiaobing Fan
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Phys Med Biol 51:N451-9. 2006
    ..The open birdcage coil offers easy access and better quality mouse cardiac imaging than both the single loop surface coil and volume birdcage coil and does not require extensive RF engineering expertise to construct...
  43. ncbi Spectrally inhomogeneous BOLD contrast changes detected in rodent tumors with high spectral and spatial resolution MRI
    Hania A al-Hallaq
    Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
    NMR Biomed 15:28-36. 2002
    ..The spectrally inhomogeneous effects of tumor oxygenating agents may reflect changes in sub-voxelar microenvironements and thus may be important for accurate evaluation of the effects of therapy...
  44. pmc Multi-parametric MR imaging of transition zone prostate cancer: Imaging features, detection and staging
    Arda Kayhan
    Arda Kayhan, Xiaobing Fan, Jacob Oommen, Aytekin Oto, Department of Radiology, University of Chicago, Chicago, IL 60637, United States
    World J Radiol 2:180-7. 2010
    ..In this article, the MR imaging features of TZ prostate cancers, the role of MR imaging in TZ cancer detection and staging, and recent advanced MR techniques will be discussed in light of the literature...