Research Topics
Genomes and GenesSpecies | A FagioliniSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Suicide attempts and ideation in patients with bipolar I disorderAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
J Clin Psychiatry 65:509-14. 2004..Suicidal thinking and behavior are common in individuals with bipolar disorder...- Obesity as a correlate of outcome in patients with bipolar I disorderAndrea Fagiolini
Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 160:112-7. 2003.... - Hypothyroidism in patients with bipolar I disorder treated primarily with lithiumAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
Epidemiol Psichiatr Soc 15:123-7. 2006..This study evaluated the frequency and clinical significance of abnormal Thyroid Stimulating Hormone (TSH) and Free Thyroxine Index (FTI) in patients with bipolar I disorder treated primarily with lithium... - Tolerability of combined treatment with lithium and paroxetine in patients with bipolar disorder and depressionA Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania 15213, USA
J Clin Psychopharmacol 21:474-8. 2001..Clinicians should be aware of the possible development of a serotonin syndrome among patients in whom paroxetine is added to ongoing lithium treatment... - Influence of panic-agoraphobic spectrum symptoms on treatment response in patients with recurrent major depressionE Frank
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213, USA
Am J Psychiatry 157:1101-7. 2000..The authors tested the hypothesis that a lifetime history of panic-agoraphobic spectrum symptoms predicts a poorer response to depression treatment... 
Treatment-emergent suicidal ideation during 4 months of acute management of unipolar major depression with SSRI pharmacotherapy or interpersonal psychotherapy in a randomized clinical trialP Rucci
Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Depress Anxiety 28:303-9. 2011....- Predictors and moderators of time to remission of major depression with interpersonal psychotherapy and SSRI pharmacotherapyE Frank
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Psychol Med 41:151-62. 2011..We sought to determine whether measures of spectrum psychopathology are useful in deciding which patients with unipolar depression should receive pharmacotherapy versus depression-specific psychotherapy... 
Comparative outcomes among the problem areas of interpersonal psychotherapy for depressionJ C Levenson
Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Depress Anxiety 27:434-40. 2010..Moreover, we sought to understand how the patient characteristics and interpersonal problems most closely linked to the onset of a patient's current depression contributed to IPT success...- Clinical indicators for the use of antidepressants in the treatment of bipolar I depressionA Fagiolini
Department of Psychiatry University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Bipolar Disord 4:277-82. 2002..Larger, prospective, and controlled studies are needed to verify our results and to identify additional indicators for a mood stabilizer and antidepressant combination treatment strategy... - Personality pathology and outcome in recurrently depressed women over 2 years of maintenance interpersonal psychotherapyJ M Cyranowski
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, PA 15213, USA
Psychol Med 34:659-69. 2004..Future maintenance treatment trials are needed to clarify the relationship between episodic mood disorder and personality function over time... - Self-reported cognitive problems predict employment trajectory in patients with bipolar I disorderA M Gilbert
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, United States
J Affect Disord 124:324-8. 2010..Cognitive impairment in bipolar disorder has been associated with poor functional outcomes. We examined the relation of self-reported cognitive problems to employment trajectory in patients diagnosed with bipolar I disorder... - Gender moderates the relationship between mania spectrum and serotonin transporter polymorphisms in depressionP Rucci
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Am J Med Genet B Neuropsychiatr Genet 150:907-13. 2009..These results should be considered tentative pending replication in other samples... - Weight gain and metabolic issues of medicines used for bipolar disorderAndrea Fagiolini
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2593, USA
Curr Psychiatry Rep 9:521-8. 2007.... - Schizoaffective disorder: diagnostic issues and future recommendationsGin S Malhi
Northern Clinical School, University of Sydney, Sydney, Australia
Bipolar Disord 10:215-30. 2008..This paper addresses the controversy regarding the diagnostic validity of schizoaffective disorder (SAD), a diagnosis that is used in both DSM-IV and ICD-10 and one that encroaches on both schizophrenia (SCZ) and bipolar disorder (BD)... - Mood and anxiety spectrum as a means to identify clinically relevant subtypes of bipolar I disorderAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Bipolar Disord 9:462-7. 2007..We examine the structure of mood and anxiety spectrum features in patients with BD I to identify subtypes with similar profiles... - Sexual disorders in subjects treated for mood and anxiety diseasesLetizia Bossini
J Clin Psychopharmacol 27:310-2. 2007 - The long term--maximising potential for rehabilitation in patients with schizophreniaAndrea Fagiolini
Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Eur Neuropsychopharmacol 17:S123-9. 2007..In summary, newer, atypical agents may improve efficacy, patient satisfaction, and aid long-term rehabilitation... - Gender differences in bipolar disorder type 1: a 48-week prospective follow-up of 72 patients treated in an Italian tertiary care centerAlessandra Benedetti
Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Pisa, Italy
J Nerv Ment Dis 195:93-6. 2007..Although differences may exist between bipolar I male and female subjects, prospective course does not seem to reveal differences in a 48-week period, at least when similar treatment strategies are adopted... - Aripiprazole in the treatment of schizophrenia: a consensus report produced by schizophrenia experts in ItalyGiovan B Cassano
Universita di Pisa, Casa di Cura S Rossore Viale delle Cascine, Pisa, Italy
Clin Drug Investig 27:1-13. 2007..Switching to aripiprazole from maintenance therapy with another antipsychotic also works well, provided the change is made gradually, involving tapering of the original medication... - Medication effects in neuroimaging studies of bipolar disorderMary L Phillips
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Am J Psychiatry 165:313-20. 2008..Withdrawing all individuals from medication and examining only unmedicated individuals may be clinically unfeasible, and examining only unmedicated individuals may render findings less generalizable... - Medical burden in late-life bipolar and major depressive disordersAriel G Gildengers
Intervention Research Center for Late Life Mood Disorders, Department of Psychiatry, University of Pittsburgh School of Medicine, The Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA
Am J Geriatr Psychiatry 16:194-200. 2008..The authors compare medical burden in elderly patients with bipolar disorder with that in those with major depressive disorder... - Medical monitoring in patients with bipolar disorder: a review of dataAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh Medical Center and Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
J Clin Psychiatry 69:e16. 2008..To optimize care and achieve the best possible treatment outcomes, integrated psychiatric and medical care is needed... - Integrating medical and psychiatric care in patients with bipolar disorderAndrea Fagiolini
J Clin Psychopharmacol 28:257-8. 2008 - Bipolar disorder and the metabolic syndrome: causal factors, psychiatric outcomes and economic burdenAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA
CNS Drugs 22:655-69. 2008..Prevention of weight gain and metabolic disturbances or early intervention when these are present in bipolar disorder could result in significant health and economic benefits... - Addressing the challenges of a cross-national investigation: lessons from the Pittsburgh-Pisa study of treatment-relevant phenotypes of unipolar depressionEllen Frank
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Clin Trials 5:253-61. 2008..A multi-site clinical trial that includes psychotherapy as one of the treatments presents numerous challenges related to cross-site consistency and communication... - Using computerized adaptive testing to reduce the burden of mental health assessmentRobert D Gibbons
Center for Health Statistics, University of Illinois at Chicago, Psychiatric Institute 457, M C 912, Chicago, IL 60680 6998, USA
Psychiatr Serv 59:361-8. 2008..This study investigated the combination of item response theory and computerized adaptive testing (CAT) for psychiatric measurement as a means of reducing the burden of research and clinical assessments... - Overcoming hurdles to achieving good physical health in patients treated with atypical antipsychoticsAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Eur Neuropsychopharmacol 18:S102-7. 2008.... - Physical health considerations in psychiatry: european views on recognition, monitoring and managementAndrea Fagiolini
Eur Neuropsychopharmacol 18:iii. 2008 - Impact of concurrent naturalistic pharmacotherapy on psychotherapy of complicated griefNaomi M Simon
Center for Anxiety and Traumatic Stress Disorders, Massachusetts General Hospital and Harvard Medical School, Boston MA 02114, USA
Psychiatry Res 159:31-6. 2008..77%). Our naturalistic data underscore the need for prospective, randomized controlled studies of CG pharmacotherapy and psychotherapy alone and in combination... - Mood stabilizers and atypical antipsychotics: bimodal treatments for bipolar disorderTerence A Ketter
Stanford University School of Medicine, Stanford, CA 94305, USA
Psychopharmacol Bull 39:120-46. 2006..Further investigation of combinations of agents such as mood stabilizers and atypical antipsychotics may yield valuable insights into the potential of combination therapies to enhance clinical outcomes in patients with bipolar disorder... - Prospective predictors of suicide and suicide attempts in 1,556 patients with bipolar disorders followed for up to 2 yearsLauren B Marangell
Mood Disorders Center, Menninger Department of Psychiatry, Baylor College of Medicine and the Department of Veterans Affairs, VISN 16 MIRECC, Houston, TX 77030, USA
Bipolar Disord 8:566-75. 2006.... - Cross-cultural validity of the structured clinical interview for panic-agoraphobic spectrumEllen Frank
Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Soc Psychiatry Psychiatr Epidemiol 40:283-90. 2005.... - The mood spectrum in unipolar and bipolar disorder: arguments for a unitary approachGiovanni B Cassano
Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Via Roma no 67, 56100 Pisa, Italy
Am J Psychiatry 161:1264-9. 2004.... - Conceptual underpinnings and empirical support for the mood spectrumGiovanni B Cassano
Department of Psychiatry, Neurobiology, Pharmacology and Biotechnology, University of Pisa, Via Roma 67, 56100 Pisa, Italy
Psychiatr Clin North Am 25:699-712, v. 2002..Finally, they summarize the clinical utility of such an approach to the description and assessment of patients with mood disorders... - Development and preliminary testing of the General 5-Spectrum Measure (GSM-V)Paola Rucci
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-2593, USA
Depress Anxiety 18:109-17. 2003..Additionally, it could provide a better characterization of patients with a syndromal level Axis-I disorder, who might require specific treatment strategies targeted to co-occurring subsyndromal conditions... - The panic-agoraphobic spectrum: development, description, and clinical significanceM Katherine Shear
Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Psychiatr Clin North Am 25:739-56. 2002..Such an approach holds some promise for progress in studies of neurobiologic basis of panic and may be useful in further efforts to overcome the nagging problem of the ambiguous boundaries of DSM diagnostic categories [53]... - Clinical significance of lifetime panic spectrum symptoms in the treatment of patients with bipolar I disorderEllen Frank
Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Arch Gen Psychiatry 59:905-11. 2002..We hypothesized that lifetime panic spectrum features would be associated with higher levels of suicidal ideation and a poorer response to acute treatment of the index mood episode in this patient population... - Suicide attempts in patients with bipolar I disorder during acute and maintenance phases of intensive treatment with pharmacotherapy and adjunctive psychotherapyPaola Rucci
Department of Psychiatry, Western Psychiatric Institite and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213, USA
Am J Psychiatry 159:1160-4. 2002..CONCLUSIONS: A treatment program in a maximally supportive clinical environment can significantly reduce suicidal behavior in high-risk patients with bipolar I disorder... - Prevalence of obesity and weight change during treatment in patients with bipolar I disorderAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
J Clin Psychiatry 63:528-33. 2002.... - Measuring mood spectrum: comparison of interview (SCI-MOODS) and self-report (MOODS-SR) instrumentsAntonella Armani
Department of Psychiatry, University of Pisa, Via Roma 67, 56100 Pisa, Italy
Compr Psychiatry 43:69-73. 2002..Agreement between the self-report and the interview formats was substantial. Intraclass correlation coefficients (ICC) ranged from 0.88 to 0.97. Our findings provide support for the reliability of the MOODS-SR questionnaire... - Adult separation anxiety: psychometric properties of a new structured clinical interviewJill M Cyranowski
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O'Hara Street, Pittsburgh, PA 15213, USA
J Psychiatr Res 36:77-86. 2002..These results highlight the feasibility and potential clinical utility of assessing age-appropriate symptoms of separation anxiety experienced during adulthood... - Functional impairment in the remission phase of bipolar disorderAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
Bipolar Disord 7:281-5. 2005.... - Interpersonal psychotherapy for depression with panic spectrum symptoms: a pilot studyJill M Cyranowski
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Depress Anxiety 21:140-2. 2005..A newly adapted psychosocial treatment for depression with lifetime panic spectrum symptoms was evaluated in an open pilot study... - The importance of routine for preventing recurrence in bipolar disorderEllen Frank
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O'Hara St, Pittsburgh, PA 15213, USA
Am J Psychiatry 163:981-5. 2006 - Prevalence and clinical correlates of medical comorbidities in patients with bipolar I disorder: analysis of acute-phase data from a randomized controlled trialWesley K Thompson
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15260, USA
J Clin Psychiatry 67:783-8. 2006..We studied the relationship between number of medical comorbidities in patients with bipolar I disorder and their demographic and clinical characteristics... - Obesity in patients with bipolar disorder: a biopsychosocial-behavioral modelJennifer E Wildes
Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
J Clin Psychiatry 67:904-15. 2006..We provide a model to explicate how factors representing different levels of analysis (i.e., biology, psychology, sociodemographics, and behavior) interact to influence the onset and maintenance of obesity in bipolar disorder... - Eating disorders and illness burden in patients with bipolar spectrum disordersJennifer E Wildes
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Compr Psychiatry 48:516-21. 2007.... - Metabolic syndrome in bipolar disorder: findings from the Bipolar Disorder Center for PennsylvaniansAndrea Fagiolini
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213, USA
Bipolar Disord 7:424-30. 2005..This study sought to evaluate the presence of the metabolic syndrome in a group of 171 patients with bipolar disorder who were consecutively recruited in the Bipolar Disorder Center for Pennsylvanians... - Quality of life and subthreshold affective symptomsArianna Goracci
Department of Neuroscience, Division of Psychiatry, University of Siena, Viale Bracci 1, Siena 53100, Italy
Qual Life Res 14:905-9. 2005..Our data suggests that subjects who report subthreshold affective symptomatology also report a low degree of enjoyment and satisfaction from life. The depressive aspects of the mood spectrum seem to have the greatest negative influence... - Effects of an educational intervention on weight gain in patients treated with antipsychoticsMauro Mauri
Department of Psychiatry, University of Pisa School of Medicine, Via Roma, Pisa, Italy
J Clin Psychopharmacol 26:462-6. 2006..CONCLUSIONS: Educational intervention can be an important tool for the management of weight increase in patients treated with APs. A larger prospective and controlled study is now needed to confirm our findings... - Persistent posttraumatic stress disorder following September 11 in patients with bipolar disorderMark H Pollack
Department of Psychiatry, Massachusetts General Hospital, Boston, Mass, USA
J Clin Psychiatry 67:394-9. 2006.... - The rabbit syndrome: state of the artMario Catena
Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Via Roma 67, 56100, Pisa, Italy
Curr Clin Pharmacol 2:212-6. 2007..Treatment strategy: The available data suggest that RS responds favourably to anticholinergic drugs and to the change of the antipsychotic... - Serotonin gene polymorphisms and bipolar I disorder: focus on the serotonin transporterHader A Mansour
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, U S A
Ann Med 37:590-602. 2005..Our analyses do not support association between SLC6A4 and BDI families. Further studies using sub-groups of BDI are worthwhile... - Is treatment-resistant depression a unique subtype of depression?Andrea Fagiolini
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Biol Psychiatry 53:640-8. 2003..This in turn may facilitate the identification of more effective treatment strategies... - Diagnostic guidelines for bipolar disorder: a summary of the International Society for Bipolar Disorders Diagnostic Guidelines Task Force ReportS Nassir Ghaemi
Bipolar Disorder Research Program, Department of Psychiatry, Emory University, Atlanta, GA 30322, USA
Bipolar Disord 10:117-28. 2008.... - Metabolic syndrome in patients with bipolar disorderAndrea Fagiolini
J Clin Psychiatry 69:678-9. 2008 - A pilot study of standardized treatment in geriatric bipolar disorderAriel G Gildengers
Intervention Research Center for Late-Life Mood Disorders, Department of Psychiatry, the Bipolar Disorder Center for Pennsylvanians, University of Pittsburgh School of Medicine 15213, USA
Am J Geriatr Psychiatry 13:319-23. 2005..CONCLUSIONS: Treating older adults with bipolar disorder under standardized treatment is feasible and is associated with low symptom levels. However, most older adults with bipolar disorder do not experience sustained recovery... - The use of antidepressants in bipolar disorderVirginio Salvi
Department of Neuroscience, University of Turin, Italy
J Clin Psychiatry 69:1307-18. 2008..Nevertheless, many clinicians continue to employ antidepressants, especially in the management of severe depression that is unresponsive to mood stabilizers alone...