Research Topics
| Heather L EvansSummaryAffiliation: University of Virginia Country: USA Publications
| Collaborators
|
Detail Information
Publications
Nature of gram-negative rod antibiotic resistance during antibiotic rotationHeather L Evans
Surgical Infectious Disease Research Laboratory, Department of Surgery, UVA Health System, Charlottesville, VA 22908 1380, USA
Surg Infect (Larchmt) 6:223-31. 2005..The aim of this study was to characterize the evolution of gram-negative antibiotic resistance during a study of empiric antibiotic rotation...- Cycling chemotherapy: a promising approach to reducing the morbidity and mortality of nosocomial infectionsHeather L Evans
Department of Surgery, University of Virginia Health System, Charlottesville, Virginia, USA
Drugs Today (Barc) 39:733-8. 2003..Cycling chemotherapy for empiric treatment of suspected infection is a method uniquely designed to address these challenges... - HCV infection of the transplanted liver: changing CD81 and HVR1 variants immediately after liver transplantationMichael G Hughes
Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia, USA
Am J Transplant 5:2504-13. 2005..In conclusion, HVR1 quasispecies variants differentially associate with, and infect allografts, after liver transplantation. Additionally, allografts express variable amounts of CD81 after transplantation... - Cost of Gram-negative resistanceHeather L Evans
Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA
Crit Care Med 35:89-95. 2007..We wished to test the hypothesis that rGNR infections are associated with higher resource utilization... - Effect of an intensive care unit rotating empiric antibiotic schedule on the development of hospital-acquired infections on the non-intensive care unit wardMichael G Hughes
Department of Surgery, University of Virginia, Charlottesville 22908, USA
Crit Care Med 32:53-60. 2004.... 
Differences in early- and late-onset ventilator-associated pneumonia between surgical and trauma patients in a combined surgical or trauma intensive care unitTraci L Hedrick
Department of Surgery, University of Virginia Health System, Charlottesville, Virginia, USA
J Trauma 64:714-20. 2008..We sought to compare differences in patient characteristics and outcome between early- and late-onset VAP in trauma and nontrauma surgical patients...
Choosing antibiotics for intra-abdominal infections: what do we mean by "high risk"?Brian R Swenson
Department of Surgery, University of Virginia, Charlottesville, Virginia 22908 0709, USA
Surg Infect (Larchmt) 10:29-39. 2009..The purpose of this study was to investigate patient characteristics associated with a high risk of isolation of resistant pathogens from an intra-abdominal source...- Does body mass index affect infection-related outcomes in the intensive care unit?Robert L Smith
Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
Surg Infect (Larchmt) 8:581-8. 2007..We hypothesized that increasing BMI would be an independent predictor of higher mortality rates in the surgical/trauma ICU... - Does enteral glutamine supplementation decrease infectious morbidity?Alison Saalwachter Schulman
Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 0709, USA
Surg Infect (Larchmt) 7:29-35. 2006..This study was designed to investigate the effects of supplemental enteral glutamine on the rate and outcomes of infection in critically ill surgical patients... - Reduction in rates of methicillin-resistant Staphylococcus aureus infection after introduction of quarterly linezolid-vancomycin cycling in a surgical intensive care unitRobert L Smith
Department of Surgery, University of Virginia, Charlottesville, Virginia 22908 0709, USA
Surg Infect (Larchmt) 9:423-31. 2008..Creative interventions may be required to reverse or stabilize this trend... - Outbreak of resistant Pseudomonas aeruginosa infections during a quarterly cycling antibiotic regimenTraci L Hedrick
Department of Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA
Surg Infect (Larchmt) 9:139-52. 2008..Antibiotic cycling or rotation of antimicrobial agent classes has been proposed to combat antimicrobial resistance... - Can we define the ideal duration of antibiotic therapy?Traci L Hedrick
University of Virginia Surgical Infectious Disease Laboratory, Charlottesville, VA 22908, USA
Surg Infect (Larchmt) 7:419-32. 2006..We also sought to investigate the difference between a fixed duration of therapy and one based on physiologic measures such as fever and leukocytosis... - Comparison of fungal and nonfungal infections in a broad-based surgical patient populationMichael G Hughes
Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
Surg Infect (Larchmt) 6:55-64. 2005..Our aim was to compare fungal and nonfungal infections among a diverse surgical patient population... - Does prior transfusion worsen outcomes from infection in surgical patients?Michael G Hughes
Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
Surg Infect (Larchmt) 4:335-43. 2003..The objective of this study was to determine the effect of transfusion on outcomes among infected surgical patients... - Timing of intubation and ventilator-associated pneumonia following injuryHeather L Evans
Department of Surgery, Harborview Medical Center, University of Washington, Seattle, 98104, USA
Arch Surg 145:1041-6. 2010.... - Ventilator-associated pneumonia: bacteremia and death after traumatic injuryGRANT E O'KEEFE
Department of Surgery, University of Washington, Harborview Medical Center, Seattle, WA 98104, USA
J Trauma Acute Care Surg 72:713-9. 2012..We tested the hypothesis that bacteremia was associated with death in trauma patients who developed VAP... - Single-institutional experience with the surgical infection prevention project in intra-abdominal surgeryTraci L Hedrick
Surgical Infectious Disease Laboratory, University of Virginia Health System, Charlottesville, Virginia 22908, USA
Surg Infect (Larchmt) 8:425-35. 2007..We hypothesized that institutional implementation of a protocol targeting known risk factors would reduce the incidence of SSI associated with intra-abdominal surgery... - Contact isolation in surgical patients: a barrier to care?Heather L Evans
Department of Surgery, UVA Health System, Charlottesville, VA 22908, USA
Surgery 134:180-8. 2003..Contact isolation is commonly used to prevent transmission of resistant organisms. We hypothesized that contact isolation negatively impacts the amount of direct patient care... - Primary human hepatocytes in spheroid formation to study hepatitis C infectionTae W Chong
Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
J Surg Res 130:52-7. 2006..As hepatocytes are the primary reservoir for the virus in vivo, we report on a model using primary human hepatocytes cultured in spheroid formation... - Duration of antibiotic therapy for ventilator-associated pneumonia caused by non-fermentative gram-negative bacilliTraci L Hedrick
University of Virginia Surgical Infectious Disease Laboratory, Charlottesville, Virginia 22908, USA
Surg Infect (Larchmt) 8:589-97. 2007..We recently examined our institutional experience with VAP caused by NFGNB to determine whether shorter courses of antibiotic therapy were associated with higher rates of recurrence... - Preventing bacterial resistance in surgical patientsHeather L Evans
Department of Surgery, University of Washington, Harborview Medical Center, Seattle, WA 98104 2499, USA
Surg Clin North Am 89:501-19, x. 2009..The use of antibiotic cycling programs for critically ill patients may be another approach to preserving the efficacy of the currently antimicrobial against the continued pressure of increasing bacterial resistance... - Does the addition of glutamine to enteral feeds affect patient mortality?Alison Saalwachter Schulman
Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA
Crit Care Med 33:2501-6. 2005..The objective was to study in a prospective fashion the effects of adding glutamine to standard or immune-modulated (supplemented with omega-3 fatty acids, beta-carotene, and amino acids such as glutamine and arginine) tube feeds... - Serum estradiol concentration as a predictor of death in critically ill and injured adultsLesly A Dossett
Division of Trauma and Surgical Critical Care, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee 37212, USA
Surg Infect (Larchmt) 9:41-8. 2008..Our objective was to determine the predictive ability and test characteristics of the serum estradiol concentration at 48 h in critically ill patients... - Pre-hospital intubation factors and pneumonia in trauma patientsHeather L Evans
Department of Surgery, Harborview Medical Center, University of Washington, Seattle, Washington 98104, USA
Surg Infect (Larchmt) 12:339-44. 2011..A subset of PH intubations with continuous quality assessment was re-examined to identify the intubation factors associated with VAP... - Impact of immunomodulatory oligodeoxynucleotides on cytokine production in the lipopolysaccharide-stimulated human whole blood modelRobert L Smith
Surgical Infectious Disease Research Laboratory, Department of Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA
Surgery 136:464-72. 2004..With further examination, we may find that these observed immunomodulatory differences could potentially be exploited for therapeutic benefit... - E2 quasispecies specificity of hepatitis C virus association with allografts immediately after liver transplantationMichael G Hughes
University of Virginia, Department of Surgery, Surgical Infectious Disease Laboratory, Charlottesville, VA, USA
Liver Transpl 10:208-16. 2004..02 and P = 0.04, respectively). Immediately after transplantation but before actual infection, liver allografts select out from the infecting serum inoculum a less heterogeneous, more closely related population of quasispecies variants... - Impact of antibiotic-resistant Gram-negative bacilli infections on outcome in hospitalized patientsDaniel P Raymond
Surgical Infectious Disease Research Laboratory, Department of Surgery, University of Virginia, Charlottesville, VA, USA
Crit Care Med 31:1035-41. 2003..Therefore, altering infection-control practices to limit the dissemination of certain bacterial species may be more effective than attempts to control only antibiotic-resistant isolates... - Lymphoscintigraphy and sentinel node biopsy accurately stage melanoma in patients presenting after wide local excisionHeather L Evans
Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
Ann Surg Oncol 10:416-25. 2003..Patients have traditionally been considered candidates for sentinel node biopsy (SNBx) only at the time of wide local excision (WLE). We hypothesized that patients with prior WLE may also be staged accurately with SNBx... - Helicopter transport: help or hindrance?Rebecca E Plevin
Department of Surgery, Harborview Medical Center, University of Washington, Seattle, Washington, USA
Curr Opin Crit Care 17:596-600. 2011..Individual trauma systems should conduct an assessment of their resources and needs in order to most effectively incorporate helicopter transport into their triage model... - Effect of chlorhexidine whole-body bathing on hospital-acquired infections among trauma patientsHeather L Evans
Department of Surgery, Harborview Medical Center, 325 9th Ave, Seattle, WA 98104, USA
Arch Surg 145:240-6. 2010..To demonstrate whether daily bathing with cloths impregnated with 2% chlorhexidine gluconate will decrease colonization of resistant bacteria and reduce the rates of health care-associated infections in critically injured patients...