Research Topics
| D L EvansSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Selective serotonin reuptake inhibitor and substance P antagonist enhancement of natural killer cell innate immunity in human immunodeficiency virus/acquired immunodeficiency syndromeDwight L Evans
Department of Psychiatry, Joseph J Stokes Research Institute of The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Biol Psychiatry 63:899-905. 2008..This study examines the potential role of three underlying regulatory systems that have been under investigation in central nervous system research as well as immune and viral research: serotonin, neurokinin, and glucocorticoid systems...
Mood disorders in the medically ill: scientific review and recommendationsDwight L Evans
School of Medicine, University of Pennsylvania, 423 Guardian Drive, Philadelphia, PA 19104, USA
Biol Psychiatry 58:175-89. 2005....
Association of depression with viral load, CD8 T lymphocytes, and natural killer cells in women with HIV infectionDwight L Evans
Department of Psychiatry, University of Pennsylvania School of Medicine, 305 Blockley Hall, Philadelphia, PA 19104 6021, USA
Am J Psychiatry 159:1752-9. 2002..This study sought to determine if depression was associated with alterations in cellular immunity variables-specifically, natural killer (NK) cells and CD8 T lymphocytes-in women with HIV infection...
Bipolar disorder: diagnostic challenges and treatment considerationsD L Evans
Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
J Clin Psychiatry 61:26-31. 2000....
Impact of stressful life events, depression, social support, coping, and cortisol on progression to AIDSJ Leserman
Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill 27599 7160, USA
Am J Psychiatry 157:1221-8. 2000..This study examined prospectively the effects of stressful events, depressive symptoms, social support, coping methods, and cortisol levels on progression of HIV-1 infection...
Progression to AIDS: the effects of stress, depressive symptoms, and social supportJ Leserman
Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill 27599 7160, USA
Psychosom Med 61:397-406. 1999..We examined the effects of stress, depressive symptoms, and social support on the progression of HIV infection...
High versus low basal cortisol secretion in asymptomatic, medication-free HIV-infected men: differential effects of severe life stress on parameters of immune statusJ M Petitto
Department of Psychiatry, University of Florida College of Medicine, Gainesville, USA
Behav Med 25:143-51. 2000..These data suggest that severe stress in combination with high glucocorticoid activity may modify select parameters of immune status in HIV-infected men...
Detection and diagnosis of psychiatric disorders in primary medical care settingsJ P Staab
Department of Psychiatry, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
Med Clin North Am 85:579-96. 2001..More research, particularly prospective studies, is needed to confirm the effectiveness of this approach and expand it beyond the few available studies that have focused mostly on depressive disorders...
Psychosocial-immune relationships in HIV diseaseD G Cruess
Department of Psychology, University of Pennsylvania, Philadelphia, 19104-6196, USA
Semin Clin Neuropsychiatry 6:241-51. 2001..We conclude by suggesting some areas for future research, particularly the study of HIV-positive women...
Physiological effects of electroconvulsive therapy and transcranial magnetic stimulation in major depressionM P Szuba
Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Depress Anxiety 12:170-7. 2000....
Acute mood and thyroid stimulating hormone effects of transcranial magnetic stimulation in major depressionM P Szuba
University of Pennsylvania, Department of Psychiatry, Philadelphia, Pennsylvania 19104, USA
Biol Psychiatry 50:22-7. 2001..CONCLUSIONS: This blinded, placebo-controlled trial documents that individual rTMS sessions can acutely elevate mood and stimulate TSH release in patients experiencing major depressive episodes...
Efficacy of venlafaxine in geriatric depressionJ P Staab
Department of Psychiatry, University of Pennsylvania Health System, Philadelphia, USA
Depress Anxiety 12:63-8. 2000..Finally, emerging data suggest that venlafaxine may be effective for conditions such as stroke, anxiety, and neuropathic pain that frequently accompany depressive disorders in the elderly...
Neuroimmunologic aspects of sleep and sleep lossN L Rogers
Department of Psychiatry, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
Semin Clin Neuropsychiatry 6:295-307. 2001..Interspersed will be proposals for future research that may illuminate the clinical relevance of the relationships between sleeping, sleep loss and immune function in humans...
Progression to AIDS, a clinical AIDS condition and mortality: psychosocial and physiological predictorsJ Leserman
Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill 27599-7160, USA
Psychol Med 32:1059-73. 2002....
A streamlined method for diagnosing common psychiatric disorders in primary careJ P Staab
Department of Psychiatry, University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA
Clin Cornerstone 3:1-9. 2001..The screening questions and confirmatory examination can be incorporated easily into most primary care practices...
Elevated substance P levels in HIV-infected menS D Douglas
Section of Immunology, Division of Immunologic and Infectious Diseases, The Joseph Stokes Jr Research Institute, The Children's Hospital of Philadelphia, PA, USA
AIDS 15:2043-5. 2001..The balance between substance P expression and functions of immune cells may be important in the immunopathogenesis of HIV infection...
Paroxetine for prevention of depressive symptoms induced by interferon-alpha and ribavirin for hepatitis CC L Raison
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA
Aliment Pharmacol Ther 25:1163-74. 2007..Whether antidepressants prevent depression during interferon-alpha/ribavirin treatment for hepatitis C virus infection has yet to be established...
Risk factors for musculoskeletal injuries in 2-year-old Thoroughbred racehorsesN Cogger
Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia
Prev Vet Med 74:36-43. 2006..More analysis using multi-level modelling is required to determine the relationship between trainer- and track-related risk factors...
Activation of natural killer-like YT-INDY cells by oligodeoxynucleotides and binding by homologous pattern recognition proteinsH Kaur
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, 30602, USA
Scand J Immunol 62:361-70. 2005..These experiments demonstrated that Po single base dG20 and CpG ODN bind to a (potential) new class of cell-surface proteins that mediate the activation of YT-INDY cells...
Single-base oligodeoxyguanosine-binding proteins on nonspecific cytotoxic cells: identification of a new class of pattern-recognition receptorsH Kaur
Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Scand J Immunol 60:238-48. 2004..The single-base ODN-binding proteins may represent a new class of pattern-recognition receptors that are involved in innate anti-bacterial resistance mediated by NCC...
Animal behaviour learning environment: software to facilitate learning in canine and feline behavior therapyP D McGreevy
Animal Behaviour, Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia
J Vet Med Educ 30:308-17. 2003..The activity concludes with a software-generated e-mail submission that includes the recorded history, diagnosis, and recommended treatment for assessment purposes...
Streptococcus iniae inhibition of apoptosis of nonspecific cytotoxic cells: a mechanism of activation of innate immunity in teleostsS L Taylor
Department of Medical Microbiology and Parasitology, College of Veterinary Medicine, University of Georgia, Athens, USA
Dis Aquat Organ 46:15-21. 2001..Understanding the relevance of these bacterial effects on NCC may be an important consideration in the evaluation of isolates used in vaccine/ bacterin production...
Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depressionC B Nemeroff
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, 1639 Pierce Dr, Suite 4000, Atlanta, GA 30322, USA
Am J Psychiatry 158:906-12. 2001..However, antidepressant therapy may be beneficial for patients who cannot tolerate high serum lithium levels or who have symptoms that are refractory to the antidepressant effects of lithium...
Flow cytometry-based assay for determination of teleost cytotoxic cell lysis of target cellsM Oumouna
Department of Medical Microbiology and Parasitology, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602, USA
Cytometry 45:259-66. 2001..HL-60 lysis by tilapia NCC exhibited saturable kinetics but occurred at different times post-cocultivation...
Activation of nonspecific cytotoxic cells (NCC) with synthetic oligodeoxynucleotides and bacterial genomic DNA: binding, specificity and identification of unique immunostimulatory motifsM Oumouna
Department of Medical Microbiology and Parasitology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
Dev Comp Immunol 26:257-69. 2002..These studies suggested that NCC recognize bacterial nonmethylated DNA. The consequences of these interactions may be increased innate and acquired anti-bacterial immunity...
