A Espinosa-Jeffrey

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation
    Araceli Espinosa-Jeffrey
    David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Curr Protoc Stem Cell Biol . 2009
  2. pmc Voluntary exercise increases oligodendrogenesis in spinal cord
    W Krityakiarana
    Intellectual and Developmental Disability Research Center, Semel Institute for Neuroscience and Human Behavior Department of Neurobiology, David Geffen, School of Medicine at UCLA, Los Angeles, California 90095, USA
    Int J Neurosci 120:280-90. 2010
  3. pmc Impact of simulated microgravity on oligodendrocyte development: implications for central nervous system repair
    Araceli Espinosa-Jeffrey
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Intellectual and Developmental Disabilities Research Center, Los Angeles, California, United States of America
    PLoS ONE 8:e76963. 2013
  4. ncbi request reprint Strategies for endogenous spinal cord repair: HPMA hydrogel to recruit migrating endogenous stem cells
    Araceli Espinosa-Jeffrey
    Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience, University of California Los Angeles, Los Angeles, California, USA
    Adv Exp Med Biol 760:25-52. 2012
  5. doi request reprint Functional central nervous system myelin repair in an adult mouse model of demyelination caused by proteolipid protein overexpression
    A Espinosa-Jeffrey
    IDDRCsp, Semel Institute for Neuroscience, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    J Neurosci Res 88:1682-94. 2010
  6. ncbi request reprint Dietary iron and the integrity of the developing rat brain: a study with the artificially-reared rat pup
    A E de los Monteros
    Mental Retardation Research Center, Neuropsychiatry Institute, UCLA School of Medicine, Los Angeles, CA 90095 1759, USA
    Cell Mol Biol (Noisy-le-grand) 46:501-15. 2000
  7. ncbi request reprint Activation, proliferation and commitment of endogenous stem/progenitor cells to the oligodendrocyte lineage by TS1 in a rat model of dysmyelination
    Araceli Espinosa-Jeffrey
    Mental Retardation Research Center, Semel Institute for Neuroscience and Human Behavior and Department of Neurobiology, University of California, Los Angeles, 90095 7332, USA
    Dev Neurosci 28:488-98. 2006
  8. ncbi request reprint Selective specification of CNS stem cells into oligodendroglial or neuronal cell lineage: cell culture and transplant studies
    Araceli Espinosa-Jeffrey
    UCLA Mental Retardation Research Center and Department of Neurobiology, Los Angeles, California 90095 1759, USA
    J Neurosci Res 69:810-25. 2002
  9. ncbi request reprint In vitro injury model for oligodendrocytes: development, injury, and recovery
    A E de los Monteros
    Mental Retardation Research Center, Neuropsychiatric Institute, Department of Neurobiology UCLA School of Medicine, 760 Westwood Plaza, Room 78 177 NPI, Los Angeles, CA 90095 1759, USA
    Microsc Res Tech 52:719-30. 2001
  10. ncbi request reprint Remyelination of the adult demyelinated mouse brain by grafted oligodendrocyte progenitors and the effect of B-104 cografts
    A Espinosa de los Monteros
    Mental Retardation Research Center, Neuropsychiatric Institute, Departments of Neurobiology and Psychiatry, UCLA School of Medicine, Los Angeles, CA, USA
    Neurochem Res 26:673-82. 2001

Collaborators

Detail Information

Publications17

  1. doi request reprint Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation
    Araceli Espinosa-Jeffrey
    David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    Curr Protoc Stem Cell Biol . 2009
    ....
  2. pmc Voluntary exercise increases oligodendrogenesis in spinal cord
    W Krityakiarana
    Intellectual and Developmental Disability Research Center, Semel Institute for Neuroscience and Human Behavior Department of Neurobiology, David Geffen, School of Medicine at UCLA, Los Angeles, California 90095, USA
    Int J Neurosci 120:280-90. 2010
    ..These results suggest that voluntary exercise positively influences oligodendrogenesis in the intact spinal cord, emphasizing the beneficial effects of voluntary exercise as a possible co-treatment for spinal cord injury...
  3. pmc Impact of simulated microgravity on oligodendrocyte development: implications for central nervous system repair
    Araceli Espinosa-Jeffrey
    Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Intellectual and Developmental Disabilities Research Center, Los Angeles, California, United States of America
    PLoS ONE 8:e76963. 2013
    ..To our knowledge, this is the first report on the gravitational modulation of oligodendrocyte intrinsic plasticity to increase their progenies. ..
  4. ncbi request reprint Strategies for endogenous spinal cord repair: HPMA hydrogel to recruit migrating endogenous stem cells
    Araceli Espinosa-Jeffrey
    Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience, University of California Los Angeles, Los Angeles, California, USA
    Adv Exp Med Biol 760:25-52. 2012
    ..Therefore, endogenous pre-existing and newly formed cells populated the gel scaffold established contact with the non injured tissue and lead to recovery of function...
  5. doi request reprint Functional central nervous system myelin repair in an adult mouse model of demyelination caused by proteolipid protein overexpression
    A Espinosa-Jeffrey
    IDDRCsp, Semel Institute for Neuroscience, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    J Neurosci Res 88:1682-94. 2010
    ..When the interventions were administered prior to hindlimb paralysis, He4e mice were able to walk up to 1 year of age without paralysis...
  6. ncbi request reprint Dietary iron and the integrity of the developing rat brain: a study with the artificially-reared rat pup
    A E de los Monteros
    Mental Retardation Research Center, Neuropsychiatry Institute, UCLA School of Medicine, Los Angeles, CA 90095 1759, USA
    Cell Mol Biol (Noisy-le-grand) 46:501-15. 2000
    ..However, the iron status profoundly influences the development of myelination in that the process is delayed in iron deficiency...
  7. ncbi request reprint Activation, proliferation and commitment of endogenous stem/progenitor cells to the oligodendrocyte lineage by TS1 in a rat model of dysmyelination
    Araceli Espinosa-Jeffrey
    Mental Retardation Research Center, Semel Institute for Neuroscience and Human Behavior and Department of Neurobiology, University of California, Los Angeles, 90095 7332, USA
    Dev Neurosci 28:488-98. 2006
    ..This strategy offers for the first time the possibility of myelin restoration to treat myelin disorders...
  8. ncbi request reprint Selective specification of CNS stem cells into oligodendroglial or neuronal cell lineage: cell culture and transplant studies
    Araceli Espinosa-Jeffrey
    UCLA Mental Retardation Research Center and Department of Neurobiology, Los Angeles, California 90095 1759, USA
    J Neurosci Res 69:810-25. 2002
    ..As expected, NSCs are capable of giving rise to astrocytes in a medium favoring this phenotype...
  9. ncbi request reprint In vitro injury model for oligodendrocytes: development, injury, and recovery
    A E de los Monteros
    Mental Retardation Research Center, Neuropsychiatric Institute, Department of Neurobiology UCLA School of Medicine, 760 Westwood Plaza, Room 78 177 NPI, Los Angeles, CA 90095 1759, USA
    Microsc Res Tech 52:719-30. 2001
    ..Moreover both, serum and cryoinjury induced the expression of HSP-60 that colocalized with OL and myelin markers. The expression of GFAP by injured cells but not by normal cells corroborated the state of injury of CG4 cells...
  10. ncbi request reprint Remyelination of the adult demyelinated mouse brain by grafted oligodendrocyte progenitors and the effect of B-104 cografts
    A Espinosa de los Monteros
    Mental Retardation Research Center, Neuropsychiatric Institute, Departments of Neurobiology and Psychiatry, UCLA School of Medicine, Los Angeles, CA, USA
    Neurochem Res 26:673-82. 2001
    ..Those grafted with progenitor CG4 cells or cografts displayed a clear increase in remyelination. This data provides a new direction for the development of cell replacement therapies in demyelinating diseases...
  11. ncbi request reprint Transferrin regulates transcription of the MBP gene and its action synergizes with IGF-1 to enhance myelinogenesis in the md rat
    A Espinosa-Jeffrey
    Mental Retardation Research Center, Neuropsychiatric Institute, UCLA, Los Angeles, Calif 90024 1759, USA
    Dev Neurosci 24:227-41. 2002
    ..Thus, transferrin selectively regulates MBP at the transcriptional level and together with IGF-1 synergizes to increase both the maturation and myelinogenic properties of md and normal OL...
  12. pmc Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin
    Milan Fiala
    Department of Medicine, Greater Los Angeles Veterans Affairs Medical Center, and School of Medicine, University of California Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 104:12849-54. 2007
    ..Thus, bisdemethoxycurcumin may correct immune defects of AD patients and provide a previously uncharacterized approach to AD immunotherapy...
  13. ncbi request reprint Stem/progenitor cells in the postnatal inner ear of the GFP-nestin transgenic mouse
    Ivan A Lopez
    Department of Surgery, Division of Head and Neck, 31 25 Rehabilitation Center, 1000 Veteran Avenue, David Geffen School of Medicine, Los Angeles, CA 90095, USA
    Int J Dev Neurosci 22:205-13. 2004
    ....
  14. doi request reprint Alzheimer disease macrophages shuttle amyloid-beta from neurons to vessels, contributing to amyloid angiopathy
    Justin Zaghi
    Department of Orthopaedic Surgery, UCLA Orthopaedic Hospital Research Center, Los Angeles, CA 90095 7358, USA
    Acta Neuropathol 117:111-24. 2009
    ..In conclusion, in patients with AD, macrophages appear to shuttle Abeta from neurons to vessels where their apoptosis may release fibrillar Abeta, contributing to cerebral amyloid angiopathy...
  15. doi request reprint 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients
    Ava Masoumi
    Department of Orthopaedic Surgery, UCLA School of Medicine, Los Angeles, CA 90095 7358, USA
    J Alzheimers Dis 17:703-17. 2009
    ..Human macrophages are a new paradigm for testing immune therapies for AD...
  16. ncbi request reprint Oxidative stress and the deleterious consequences to the rat cochlea after prenatal chronic mild exposure to carbon monoxide in air
    I A Lopez
    Surgery Department Division of Head and Neck, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    Neuroscience 151:854-67. 2008
    ....
  17. ncbi request reprint Calcium modulates dopamine potentiation of N-methyl-D-aspartate responses: electrophysiological and imaging evidence
    J C Liu
    Mental Retardation Research Center, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
    J Neurosci Res 76:315-22. 2004
    ..The existence of multiple mechanisms leading to a similar outcome allows a certain degree of redundancy in the consequences of DA modulation...