N Joseph Espat

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint Soft tissue sarcoma brain metastases. Prevalence in a cohort of 3829 patients
    N Joseph Espat
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer 94:2706-11. 2002
  2. ncbi request reprint Reported outcome factors for hepatic metastasectomy
    N Joseph Espat
    Department of Surgery M C 958, University of Illinois at Chicago, 840 S Wood Street, Chicago, IL 60612, USA
    J Gastrointest Surg 10:155-160. 2006
  3. ncbi request reprint Minimally invasive treatment of esophageal cancer: laparoscopic staging to robotic esophagectomy
    N Joseph Espat
    Minimally Invasive Surgery Center, Department of Surgery, University of Illinois at Chicago, Chicago Illinois 60612, USA
    Cancer J 11:10-7. 2005
  4. ncbi request reprint Conventional hemangiopericytoma: modern analysis of outcome
    N Joseph Espat
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer 95:1746-51. 2002
  5. doi request reprint Feasibility evaluation of emodin (rhubarb extract) as an inhibitor of pancreatic cancer cell proliferation in vitro
    Jun Cai
    Department of Surgery, The University of Illinois at Chicago, USA
    JPEN J Parenter Enteral Nutr 32:190-6. 2008
  6. ncbi request reprint Inhibition of proliferation by omega-3 fatty acids in chemoresistant pancreatic cancer cells
    Justin Hering
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois, USA
    Ann Surg Oncol 14:3620-8. 2007
  7. pmc Lipopolysaccharide-stimulated RAW 264.7 macrophage inducible nitric oxide synthase and nitric oxide production is decreased by an omega-3 fatty acid lipid emulsion
    Christopher Aldridge
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois, USA
    J Surg Res 149:296-302. 2008
  8. ncbi request reprint Attenuation of iNOS in an LPS-stimulated macrophage model by omega-3 fatty acids is independent of COX-2 derived PGE2
    Anthony Razzak
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Surg Res 145:244-50. 2008
  9. doi request reprint Radiofrequency ablation of primary and metastatic liver tumors: a critical review of the literature
    Sean Garrean
    Department of Surgery, Hepatobiliary and Oncologic Surgery, University of Illinois at Chicago, Chicago, IL, USA
    Am J Surg 195:508-20. 2008
  10. ncbi request reprint Does the literature support an indication for hepatic metastasectomy other than for colorectal primary?
    Adnan Alseidi
    Department of Surgery, University of Illinois at Chicago, 60612, USA
    J Gastrointest Surg 10:99-104. 2006

Research Grants

  1. Fish Oil Modulation of Tumor Inflammation
    NOCIF ESPAT; Fiscal Year: 2006

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Soft tissue sarcoma brain metastases. Prevalence in a cohort of 3829 patients
    N Joseph Espat
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer 94:2706-11. 2002
    ..To the authors' knowledge limited information is available regarding the influence of the initial STS site, the significance of parenchymal versus leptomeningeal metastases, and the role of surgical resection...
  2. ncbi request reprint Reported outcome factors for hepatic metastasectomy
    N Joseph Espat
    Department of Surgery M C 958, University of Illinois at Chicago, 840 S Wood Street, Chicago, IL 60612, USA
    J Gastrointest Surg 10:155-160. 2006
  3. ncbi request reprint Minimally invasive treatment of esophageal cancer: laparoscopic staging to robotic esophagectomy
    N Joseph Espat
    Minimally Invasive Surgery Center, Department of Surgery, University of Illinois at Chicago, Chicago Illinois 60612, USA
    Cancer J 11:10-7. 2005
    ....
  4. ncbi request reprint Conventional hemangiopericytoma: modern analysis of outcome
    N Joseph Espat
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Cancer 95:1746-51. 2002
    ..In the current report the authors defined the clinical behavior and prognosis for patients with HPC...
  5. doi request reprint Feasibility evaluation of emodin (rhubarb extract) as an inhibitor of pancreatic cancer cell proliferation in vitro
    Jun Cai
    Department of Surgery, The University of Illinois at Chicago, USA
    JPEN J Parenter Enteral Nutr 32:190-6. 2008
    ..These feasibility experiments provide initial evidence that emodin exerts an antiproliferative effect, likely through apoptosis induction-related mechanism(s), that is reproducible in various human pancreatic cancer cell lines...
  6. ncbi request reprint Inhibition of proliferation by omega-3 fatty acids in chemoresistant pancreatic cancer cells
    Justin Hering
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois, USA
    Ann Surg Oncol 14:3620-8. 2007
    ..The well-known capacity of omega-3 fatty acids (n-3 FAs) to inhibit NF-kB activation and promote cellular apoptosis has the potential to restore or facilitate gemcitabine chemosensitivity...
  7. pmc Lipopolysaccharide-stimulated RAW 264.7 macrophage inducible nitric oxide synthase and nitric oxide production is decreased by an omega-3 fatty acid lipid emulsion
    Christopher Aldridge
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois, USA
    J Surg Res 149:296-302. 2008
    ..We hypothesized that pretreating with an omega-3 FA lipid emulsion would decrease the production of NO in macrophages and that this effect would occur through alterations in inducible nitric oxide synthetase (iNOS)...
  8. ncbi request reprint Attenuation of iNOS in an LPS-stimulated macrophage model by omega-3 fatty acids is independent of COX-2 derived PGE2
    Anthony Razzak
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Surg Res 145:244-50. 2008
    ..Selective COX-2 inhibitor (L-748,731) experiments and separate PGE2 repletion studies were used to test this hypothesis...
  9. doi request reprint Radiofrequency ablation of primary and metastatic liver tumors: a critical review of the literature
    Sean Garrean
    Department of Surgery, Hepatobiliary and Oncologic Surgery, University of Illinois at Chicago, Chicago, IL, USA
    Am J Surg 195:508-20. 2008
    ..As a result, several local ablative therapies have emerged as alternatives to resection or as adjuncts in total oncologic care. Presently, the most widely employed liver-directed treatment is radiofrequency thermal ablation...
  10. ncbi request reprint Does the literature support an indication for hepatic metastasectomy other than for colorectal primary?
    Adnan Alseidi
    Department of Surgery, University of Illinois at Chicago, 60612, USA
    J Gastrointest Surg 10:99-104. 2006
    ....
  11. ncbi request reprint A priori dietary omega-3 lipid supplementation results in local pancreatic macrophage and pulmonary inflammatory response attenuation in a model of experimental acute edematous pancreatitis (AEP)
    Suhail Sharif
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    JPEN J Parenter Enteral Nutr 30:271-6. 2006
    ....
  12. pmc Feasibility of purely laparoscopic resection of locally advanced rectal cancer in obese patients
    Tolutope Oyasiji
    Division of Surgical Oncology, Department of Surgery, Roger Williams Medical Center, Boston University, Prior 4, 825 Chalkstone Avenue, Providence, RI 02908, USA
    World J Surg Oncol 10:147. 2012
    ..There is a paucity of data on the impact of obesity on perioperative and oncologic outcomes for totally-laparoscopic rectal cancer resection (TLRR) for locally advanced disease...
  13. ncbi request reprint Gastric adenocarcinoma arising from fundic gland polyps in a patient with familial adenomatous polyposis syndrome
    Sean Garrean
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois, USA
    Am Surg 74:79-83. 2008
    ..We also review reported cases of gastric cancer in FAP and FAP variant patients in an effort to better understand the pathology, clinical course, and optimal screening and treatment strategies for this disease manifestation...
  14. ncbi request reprint Complete eradication of hepatic metastasis from colorectal cancer by Yttrium-90 SIRT
    Sean Garrean
    Department of Surgery, The University of Illinois at Chicago, 840 S Wood St MC 958, Chicago, IL 60612, United States
    World J Gastroenterol 13:3016-9. 2007
    ..The results suggest that Y-90 SIRT may have potential applications beyond its usual role as a palliative or salvage therapy for unresectable hepatic CRC...
  15. ncbi request reprint G2/M cell-cycle arrest and apoptosis by n-3 fatty acids in a pancreatic cancer model
    Thomas Dekoj
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Surg Res 139:106-12. 2007
    ..e., TNF-alpha, IL-10 and PGE(2)) in many cell lines. However, mechanisms of anti-proliferative effects have not been clearly defined...
  16. pmc Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor
    Steven C Katz
    Roger Williams Medical Center, Department of Surgery, Providence, RI Boston University School of Medicine, Boston, MA, USA
    J Transl Med 11:46. 2013
    ..The aims of this study were to develop and test novel anti-KIT dTc engineered to target GIST cells...
  17. ncbi request reprint Total laparoscopic distal pancreatectomy: beyond selected patients
    Cherif Boutros
    Department of Surgery, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Am Surg 77:1526-30. 2011
    ..This series of nonselected consecutive patients supports that LDP is technically feasible with a comparable procedural outcome to the selected-patient literature, suggesting potentially expanded indications for LDP...
  18. ncbi request reprint Robotic-assisted minimally invasive transhiatal esophagectomy
    Santiago Horgan
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Am Surg 69:624-6. 2003
    ..Technological advancements have evolved to include robotic systems for performance of complex surgical procedures. We report on our experience of using robotic-assisted technology to perform a transhiatal total esophagectomy...
  19. ncbi request reprint Hepatic intra-arterial chemotherapy
    Evan S Ong
    Department of Surgery, University of Illinois at Chicago, M C 958, 840 S Wood Street, Room 435E, Chicago, Illinois 60612, USA
    Ann Surg Oncol 13:142-9. 2006
  20. ncbi request reprint Short-term outcomes with small intestinal submucosa for ventral abdominal hernia
    W Scott Helton
    Department of Surgery, University of Illinois at Chicago, USA
    Arch Surg 140:549-60; discussion 560-2. 2005
    ..A bioabsorbable tissue scaffold of porcine submucosal small intestine extracellular matrix (Surgisis Gold [SIS]; Cook Biotech Inc, West Lafayette, Ind) mesh is safe and effective for ventral hernia repair...
  21. pmc T cell infiltrate and outcome following resection of intermediate-grade primary neuroendocrine tumours and liver metastases
    Steven C Katz
    Division of Surgical Oncology, Department of Surgery, Roger Williams Medical Center, Providence, RI, USA
    HPB (Oxford) 12:674-83. 2010
    ..Tumour-infiltrating lymphocytes (TILs) have been shown to predict survival in numerous malignancies. The importance of TILs in primary pancreatic neuroendocrine tumours (NETs) and NET liver metastases (NETLMs) has not been defined...
  22. ncbi request reprint Experimental studies defining omega-3 fatty acid antiinflammatory mechanisms and abrogation of tumor-related syndromes
    Tricia A Babcock
    Department of Surgery, University of Illinois at Chicago, Chicago, IL 60612, USA
    Nutr Clin Pract 20:62-74. 2005
    ..In this review, we discuss the recent progress made in our laboratory on defining the mechanisms of omega-3 fatty acids activity...
  23. ncbi request reprint A primer on transarterial, chemical, and thermal ablative therapies for hepatic tumors
    Sean Garrean
    Department of Surgery, University of Illinois at Chicago, 840 South Wood Street, M C 958, Chicago, IL 60612, USA
    Am J Surg 194:79-88. 2007
    ..The purpose of this review is to inclusively define the various ablation modalities available (transarterial, chemical, and thermal ablative), and to describe the procedures, general applications, and reported outcomes...
  24. ncbi request reprint Primary biliary B-cell lymphoma of the cystic duct causing obstructive jaundice
    David H Jho
    Department of Surgery, University of Illinois, Chicago, Illinois, USA
    Am Surg 73:508-10. 2007
    ..A soft, tan-yellow 1.0-cm mass was removed from the cystic duct, and infiltrating atypical lymphocytic nodules were identified with a final diagnosis of an anaplastic variant of diffuse large B-cell lymphoma...
  25. pmc Obstructive jaundice expands intrahepatic regulatory T cells, which impair liver T lymphocyte function but modulate liver cholestasis and fibrosis
    Steven C Katz
    Hepatobiliary Service, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Immunol 187:1150-6. 2011
    ..Thus, BDL expands liver Treg, which reduce the function of bulk intrahepatic T cells yet limit liver injury...
  26. ncbi request reprint SURGISIS-assisted surgical site control in the delayed repair of a complex bile duct injury after laparoscopic cholecystectomy
    Evan S Ong
    Department of Surgery, University of Illinois at Chicago, 840 S Wood Street, Chicago, IL 60612, USA
    J Gastrointest Surg 10:202-6. 2006
    ....
  27. ncbi request reprint Early experience employing a linear hepatic parenchyma coagulation device
    Cord Sturgeon
    Department of Surgery M C 958, University of Illinois at Chicago, 840 S Wood St, Room 435E, Chicago, IL 60612, USA
    J Hepatobiliary Pancreat Surg 10:81-6. 2003
    ..Resection techniques and devices that minimize hemorrhage and bile leak, and enable the preservation of functional hepatic parenchyma, have been useful in the surgical management of liver tumors...
  28. ncbi request reprint 1990-2001 US general surgery chief resident gastric surgery operative experience: analysis of paradigm shift
    N Joseph Espat
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Gastrointest Surg 8:471-8. 2004
    ..U.S. surgical chief residents report a widely variable experience in gastric surgery over the period analyzed. However, their overall experience has not significantly diminished since 1990 although specific procedural volume has varied...
  29. ncbi request reprint Synergistic anti-inflammatory activity of omega-3 lipid and rofecoxib pretreatment on macrophage proinflammatory cytokine production occurs via divergent NF-kappaB activation
    Tricia A Babcock
    Department of Surgery, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    JPEN J Parenter Enteral Nutr 28:232-9; discussion 239-40. 2004
    ..Moreover, potential synergy between omega-3 lipids and selective COX-2 inhibition is postulated...
  30. ncbi request reprint Ciliary neurotrophic factor upregulates ubiquitin-proteasome components in a rat model of neuronal injury
    David H Jho
    Department of Surgery, University of Illinois at Chicago, Chicago, IL 60612, USA
    Cytokine 27:142-51. 2004
    ..We conclude that CNTF decreases lean body weight through a combination of appetite inhibition and UPP pathway activation...
  31. ncbi request reprint Intraductal papillary mucinous neoplasms of the pancreas
    Jose G Trevino
    Department of Surgery, MC 958, 435 CSB, University of Illinois at Chicago, 840 South Wood, Chicago, IL 60612, USA
    Curr Treat Options Gastroenterol 9:385-90. 2006
    ....

Research Grants1

  1. Fish Oil Modulation of Tumor Inflammation
    NOCIF ESPAT; Fiscal Year: 2006
    ....