Research Topics
Species | Brenda EskenaziSummaryAffiliation: University of California Country: USA Publications
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Publications
Maternal perception of child weight among Mexicans in California and MexicoLisa G Rosas
University of California San Francisco, 3333 California St Suite 365, San Francisco, CA 94118, USA
Matern Child Health J 14:886-94. 2010....
Organophosphate pesticide exposure and neurodevelopment in young Mexican-American childrenBrenda Eskenazi
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
Environ Health Perspect 115:792-8. 2007..Organophosphate (OP) pesticides are widely used in agriculture and homes. Animal studies suggest that even moderate doses are neurodevelopmental toxicants, but there are few studies in humans...
Antioxidant intake is associated with semen quality in healthy menB Eskenazi
140 Earl Warren Hall, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
Hum Reprod 20:1006-12. 2005..We seek to determine whether dietary and supplement intake of specific micronutrients (zinc and folate) and antioxidants (vitamins C, E and beta-carotene) is associated with semen quality...- A comparison of PBDE serum concentrations in Mexican and Mexican-American children living in CaliforniaBrenda Eskenazi
Center for Environmental Research and Children s Health, School of Public Health, University of California at Berkeley, Berkeley, California, USA
Environ Health Perspect 119:1442-8. 2011..Polybrominated diphenyl ethers (PBDE), which are used as flame retardants, have been found to be higher in residents of California than of other parts of the United States... - PON1 and neurodevelopment in children from the CHAMACOS study exposed to organophosphate pesticides in uteroBrenda Eskenazi
Center for Environmental Research and Children s Health, School of Public Health, University of California, Berkeley, Berkeley, California 94602, USA
Environ Health Perspect 118:1775-81. 2010.... - Serum dioxin concentrations and age at menopauseBrenda Eskenazi
School of Public Health, University of California at Berkeley, Berkeley, California 94720 7360, USA
Environ Health Perspect 113:858-62. 2005..04). These results suggest a nonmonotonic dose-related association with increasing risk of earlier menopause up to about 100 ppt TCDD, but not above... - Methodologic and logistic issues in conducting longitudinal birth cohort studies: lessons learned from the Centers for Children's Environmental Health and Disease Prevention ResearchBrenda Eskenazi
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California, USA
Environ Health Perspect 113:1419-29. 2005..These centers present barriers encountered, solutions found, and considerations for future research, with the hope that the lessons learned can help inform the planning and conduct of the National Children's Study... - In utero exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment among young Mexican American childrenBrenda Eskenazi
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, 2150 Shattuck Ave, Suite 600, Berkeley, California 94720 7380, USA
Pediatrics 118:233-41. 2006..We investigated the relationship between prenatal exposure to dichlorodiphenyltrichloroethane (DDT) and dichlorodiphenyldichloroethylene (DDE) and neurodevelopment of Mexican farm-workers' children in California... 
Serum dioxin concentrations and time to pregnancyBrenda Eskenazi
School of Public Health, University of California at Berkeley, Berkeley, CA 94720 7380, USA
Epidemiology 21:224-31. 2010..In 1976, an explosion near Seveso, Italy resulted in the highest TCDD exposure known in residential populations. Twenty years later, we conducted a retrospective cohort study, the Seveso Women's Health Study...- Low birthweight in New York City and upstate New York following the events of September 11thBrenda Eskenazi
Center for Children s Environmental Health Research, School of Public Health, University of California, UC Berkeley, CA 94720 7380, USA
Hum Reprod 22:3013-20. 2007..We examined pregnancy outcomes in New York City (NYC) and upstate New York after the September 11, 2001 World Trade Center disaster... - The Pine River statement: human health consequences of DDT useBrenda Eskenazi
School of Public Health, University of California Berkeley, 2150 Shattuck Avenue, Berkeley, CA 94720, USA
Environ Health Perspect 117:1359-67. 2009..To better inform current policy, we reviewed epidemiologic studies published from 2003 to 2008 that investigated the human health consequences of DDT and/or DDE (dichlorodiphenyldichloroethylene) exposure... - Serum dioxin concentrations and risk of uterine leiomyoma in the Seveso Women's Health StudyBrenda Eskenazi
Department of Epidemiology, School of Public Health, University of California, Berkeley, CA 94720 7380, USA
Am J Epidemiol 166:79-87. 2007..0 parts per trillion. This finding suggests that TCDD may have antiestrogenic effects in the uterine myometrium, in contrast to apparently estrogenic effects previously found in the breast of Seveso Women's Health Study women... - Pesticide toxicity and the developing brainBrenda Eskenazi
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, CA 94704, USA
Basic Clin Pharmacol Toxicol 102:228-36. 2008..We also observed adverse associations of prenatal but not postnatal organophosphate pesticide exposure with mental development and pervasive developmental disorder at 24 months... - Effects of exposure to polychlorinated biphenyls and organochlorine pesticides on thyroid function during pregnancyJonathan Chevrier
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, Berkeley, CA 94704 7380, USA
Am J Epidemiol 168:298-310. 2008..These findings are of particular significance, since thyroid hormones of maternal origin may play an essential role in fetal neurodevelopment... - Determinants of organophosphorus pesticide urinary metabolite levels in young children living in an agricultural communityAsa Bradman
Center for Environmental Research and Children s Health, School of Public Health, University of California at Berkeley, 1995 University Avenue, Berkeley, CA 94720, USA
Int J Environ Res Public Health 8:1061-83. 2011..The impact of these determinants varied by age and class of DAP metabolite... - Micronutrients intake is associated with improved sperm DNA quality in older menThomas E Schmid
Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California Biosciences Directorate, Lawrence Livermore National Laboratory, Livermore, California
Fertil Steril 98:1130-1137.e1. 2012..To investigate whether lifestyle factors such as increased dietary intake of micronutrients reduce the risks of sperm DNA damage, and whether older men benefit more than younger men... - Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural communityKaren Huen
Center for Environmental Research and Children s Health, School of Public Health, University of California, Berkeley, 1995 University Avenue Suite 265, Berkeley CA 94720, USA
Environ Res 117:8-16. 2012..However, compared to their mothers, newborns have much lower quantities of the detoxifying PON1 enzyme suggesting that infants may be especially vulnerable to organophosphate pesticide exposures... - Relationship of serum TCDD concentrations and age at exposure of female residents of Seveso, ItalyBrenda Eskenazi
School of Public Health, University of California at Berkeley, 2150 Shattuck Avenue, Berkeley, CA 94720 7380, USA
Environ Health Perspect 112:22-7. 2004..As a consequence, previous SWHS studies that considered only TCDD exposure may have underestimated health effects due to total TEQ concentrations... - Factors associated with serum polybrominated diphenyl ether (PBDE) levels among school-age children in the CHAMACOS cohortAsa Bradman
Center for Environmental Research and Children s Health, School of Public Health, University of California, Berkeley, California, United States
Environ Sci Technol 46:7373-81. 2012..S. population. Additional research is needed to assess the health impacts of these exposures... - Association of organophosphate pesticide exposure and paraoxonase with birth outcome in Mexican-American womenKim G Harley
Center for Environmental Research and Children s Health, School of Public Health, University of California, Berkeley, California, United States of America
PLoS ONE 6:e23923. 2011..We explored whether paraoxonase (PON1), a key enzyme involved in detoxification of OPs, could be an effect modifier in this association... - Pesticides in house dust from urban and farmworker households in California: an observational measurement studyLesliam Quirós-Alcalá
Center for Environmental Research and Children s Health, School of Public Health, University of California, 1995 University Avenue Suite 265, Berkeley, CA 94704, USA
Environ Health 10:19. 2011..e., chlorpyrifos and diazinon) have declined in homes in the agricultural community; and estimate resident children's pesticide exposures via inadvertent dust ingestion... - Maternal serum dioxin levels and birth outcomes in women of Seveso, ItalyBrenda Eskenazi
School of Public Health, University of California at Berkeley, Berkeley, California 94720 7360, USA
Environ Health Perspect 111:947-53. 2003..It remains possible that the effects of TCDD on birth outcomes are yet to be observed, because the most heavily exposed women in Seveso were the youngest and the least likely to have yet had a pregnancy... - DDT exposure, work in agriculture, and time to pregnancy among farmworkers in CaliforniaKim G Harley
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, Calif 94704 7380, USA
J Occup Environ Med 50:1335-42. 2008..This study examined whether exposure to pesticides, including dichlorodiphenyltrichloroethane (DDT), was associated with longer time to pregnancy (TTP)... - Pesticides in dust from homes in an agricultural areaMartha E Harnly
Environmental Health Investigations Branch, California Department of Public Health, Richmond, California, USA
Environ Sci Technol 43:8767-74. 2009..0, a very low vapor pressure, or both. Health risk assessments for pesticides that have these properties may need to include evaluation of exposures to house dust... - Early environmental exposures and intracellular Th1/Th2 cytokine profiles in 24-month-old children living in an agricultural areaPaurene Duramad
Center for Children's Environmental Health, School of Public Health, University of California, Berkeley, California 94720-7460, USA
Environ Health Perspect 114:1916-22. 2006..Our data further suggest that early exposures to an agricultural environment, breast-feeding, pets, and gas stoves affect the development of children's Th1/Th2 immune response... - Merging models and biomonitoring data to characterize sources and pathways of human exposure to organophosphorus pesticides in the Salinas Valley of CaliforniaThomas E McKone
Lawrence Berkeley National Laboratory, Berkeley, California, Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California, USA
Environ Sci Technol 41:3233-40. 2007..These results show that mass-balance models can estimate exposures for OP pesticides within the range measured by biological monitoring... - Occupational exposure to benzene and chromosomal structural aberrations in the sperm of Chinese menFrancesco Marchetti
Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
Environ Health Perspect 120:229-34. 2012..We previously reported that occupational exposures near the U.S. Occupational Safety and Health Administration permissible exposure limit (8 hr) of 1 ppm was associated with sperm aneuploidy... - Organophosphate pesticide exposure and attention in young Mexican-American children: the CHAMACOS studyAmy R Marks
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, Berkeley, California 94720, USA
Environ Health Perspect 118:1768-74. 2010..Exposure to organophosphate (OP) pesticides, well-known neurotoxicants, has been associated with neurobehavioral deficits in children... - Serum dioxin concentrations and menstrual cycle characteristicsBrenda Eskenazi
School of Public Health, University of California at Berkeley, Berkeley, CA 94720 7360, USA
Am J Epidemiol 156:383-92. 2002..16 days, 95% CI: -0.08, 0.41). These results are consistent with effects of TCDD on ovarian function noted in some animal species and with greater sensitivity to TCDD during development... - Determinants of serum polybrominated diphenyl ether (PBDE) levels among pregnant women in the CHAMACOS cohortRosemary Castorina
Center for Environmental Research and Children s Health CERCH, School of Public Health, University of California, Berkeley, California, United States
Environ Sci Technol 45:6553-60. 2011..8% (95% CI = 2.0, 57.5) increase in women's serum PBDE levels. Findings suggest PBDE indoor contamination in California homes is contributing to human exposures in a population of recent immigrants... - Longitudinal changes in PON1 enzymatic activities in Mexican-American mothers and children with different genotypes and haplotypesKaren Huen
Center for Children s Environmental Health, 50 University Hall, School of Public Health, University of California, Berkeley, CA 94720 7360, USA
Toxicol Appl Pharmacol 244:181-9. 2010..In addition to known PON1 polymorphisms, unidentified environmental, genetic, or epigenetic factors may also influence variability of PON1 expression and therefore susceptibility to OPs and oxidative stress... - Organophosphate urinary metabolite levels during pregnancy and after delivery in women living in an agricultural communityAsa Bradman
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
Environ Health Perspect 113:1802-7. 2005..S. reference levels was most pronounced after delivery. Higher DAP metabolite levels in the immediate postpartum period may have implications for estimating dose during pregnancy and for exposure during lactation... - Comparison of current-use pesticide and other toxicant urinary metabolite levels among pregnant women in the CHAMACOS cohort and NHANESRosemary Castorina
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94704, USA
Environ Health Perspect 118:856-63. 2010..S. national reference data for 342 pregnant women sampled by the National Health and Nutrition Examination Survey (1999-2002)... - Serum dioxin concentrations and endometriosis: a cohort study in Seveso, ItalyBrenda Eskenazi
Center for Children s Environmental Health, School of Public Health, University of California at Berkeley, Berkeley, California 94720, USA
Environ Health Perspect 110:629-34. 2002..Unavoidable disease misclassification in a population-based study may have led to an underestimate of the true risk of endometriosis... - Comparison of aneuploidies of chromosomes 21, X, and Y in the blood lymphocytes and sperm of workers exposed to benzeneZhiying Ji
Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, California, USA
Environ Mol Mutagen 53:218-26. 2012..The findings suggest that benzene exposure induces aneuploidies in both blood cells and sperm within the same individuals, but selectively affects chromosome 21 in blood lymphocytes and the sex chromosomes in sperm... - Serum persistent organic pollutants and duration of lactation among Mexican-American womenRosana H Weldon
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, CA 94704, USA
J Environ Public Health 2010:861757. 2010..Research suggests that estrogenic endocrine-disrupting chemicals interfere with lactation... - Serum dioxin concentrations and age at menarcheMarcella Warner
School of Public Health, University of California at Berkeley, Berkeley, California 94720 7380, USA
Environ Health Perspect 112:1289-92. 2004..Given that animal evidence suggests in utero exposure has the most significant effect on onset of puberty, continued follow-up of the offspring of the SWHS cohort is important... - Pesticides and their metabolites in the homes and urine of farmworker children living in the Salinas Valley, CAAsa Bradman
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, CA 94720 7380, USA
J Expo Sci Environ Epidemiol 17:331-49. 2007..The child activity timeline, a novel, low-literacy instrument based on pictures, was successfully used by our participants. Future uses of these data include the development of pesticide exposure models and risk assessment... - Community-based intervention to reduce pesticide exposure to farmworkers and potential take-home exposure to their familiesAsa Bradman
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
J Expo Sci Environ Epidemiol 19:79-89. 2009..Additionally, wearing gloves and removing work clothes before returning home could reduce transport of pesticides to worker homes. Behavioral interventions are needed to reduce consumption of strawberries in the field... - Serum dioxin concentrations and quality of ovarian function in women of SevesoMarcella Warner
School of Public Health, University of California at Berkeley, Berkeley, California 94720 7360, USA
Environ Health Perspect 115:336-40. 2007..On 10 July 1976, an explosion exposed residents of Seveso, Italy, to the highest levels of TCDD in a population. Twenty years later, we initiated the Seveso Women's Health Study to study reproductive health... - Association of prenatal exposure to polybrominated diphenyl ethers and infant birth weightKim G Harley
Center for Environmental Research and Children s Health, School of Public Health, University of California, Berkeley, Berkeley, CA 94704, USA
Am J Epidemiol 174:885-92. 2011..These findings were diminished slightly and were no longer statistically significant when maternal weight gain was included in the models. PBDE congeners were not associated with birth length, head circumference, or gestational duration... - Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and childrenKaren Huen
Center for Children s Environmental Health, School of Public Health, University of California, Berkeley, California, USA
Environ Mol Mutagen 52:105-16. 2011..Functional effects of PON genetic variation related to susceptibility to OPs and oxidative stress also differed by age and should be considered in protecting vulnerable subpopulations... - Prenatal exposure to polybrominated diphenyl ether flame retardants and neonatal thyroid-stimulating hormone levels in the CHAMACOS studyJonathan Chevrier
Center for Environmental Research and Children s Health, School of Public Health, University of California Berkeley, 1995 University Avenue, Berkeley, CA 94704 7392, USA
Am J Epidemiol 174:1166-74. 2011..Results were robust to sensitivity analysis. The authors found no conclusive evidence that prenatal exposure to PBDEs at levels similar to those of the general US population is related to neonatal TSH... - Factors predicting organochlorine pesticide levels in pregnant Latina women living in a United States agricultural areaA S A Bradman
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, CA 94720 7380, USA
J Expo Sci Environ Epidemiol 17:388-99. 2007..Although the weight of evidence from this study indicates that most exposure occurred before moving to the United States, the results for HCB indicate the possibility of ongoing exposure in this country... - Serum dioxin concentrations and breast cancer risk in the Seveso Women's Health StudyMarcella Warner
School of Public Health, University of California at Berkeley, Berkeley, California 94720, USA
Environ Health Perspect 110:625-8. 2002..Individual serum TCDD is significantly related with breast cancer incidence among women in the SWHS cohort. Continued follow-up of the cohort will help shed light on the possible role of TCDD in the pathogenesis of breast cancer... - A community-based participatory worksite intervention to reduce pesticide exposures to farmworkers and their familiesAlicia L Salvatore
Berkeley Media Studies Group, Berkeley, CA 94704, USA
Am J Public Health 99:S578-81. 2009..Some behaviors, such as hand washing before eating and many targeted after-work behaviors, did not improve, indicating a need for additional intervention... - Soda consumption and overweight status of 2-year-old mexican-american children in californiaMarcella L Warner
Center for Children s Environmental Health Research, School of Public Health, University of California, 2150 Shattuck Avenue, Suite 600, Berkeley, CA 94720 7380, USA
Obesity (Silver Spring) 14:1966-74. 2006..The objective of this study was to determine the association between current soda consumption and overweight in 2-year-old Mexican-American children... - Dietary associations of household food insecurity among children of Mexican descent: results of a binational studyLisa G Rosas
Center on Social Disparities in Health, University of California, San Francisco, CA, USA
J Am Diet Assoc 109:2001-9. 2009..This study aimed to understand the level of perceived food insecurity and its association with dietary intake among children of Mexican descent residing in the United States and Mexico... - PBDE concentrations in women's serum and fecundabilityKim G Harley
Center for Children s Environmental Health Research, School of Public Health, University of California Berkeley, Berkeley, California, USA
Environ Health Perspect 118:699-704. 2010..Although PBDEs have been associated with reproductive and hormonal effects in animals, no human studies have examined their association with fertility... - Association between in utero organophosphate pesticide exposure and abnormal reflexes in neonatesJessica G Young
Center for Children's Environmental Health Research, School of Public Health, UC Berkeley, 2150 Shattuck Ave, Suite 600, Berkeley, CA 94720-7380, USA
Neurotoxicology 26:199-209. 2005..Whether neonatal reflex functioning is predictive of neuropsychological functioning as the child matures will continue to be evaluated in this birth cohort... - Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural populationBrenda Eskenazi
Center for Children s Environmental Health Research, School of Public Health, University of California Berkeley, 94720 7380, USA
Environ Health Perspect 112:1116-24. 2004..However, despite these observed associations, the rate of preterm delivery in this population (6.4%) was lower than in a U.S. reference population... - A pilot study of pesticides and PCBs in the breast milk of women residing in urban and agricultural communities of CaliforniaRosana Hernandez Weldon
Center for Environmental Research and Children s Health, School of Public Health, University of California, 1995 University Ave, Suite 265, Berkeley, CA 94704, USA
J Environ Monit 13:3136-44. 2011..02 and 4.32 pg g(-1) milk for chlorpyrifos-methyl and propoxur, respectively. These results suggest that neonates and young children may be exposed to persistent and non-persistent pesticides and PCBs via breast milk... - Prenatal exposure to organophosphate pesticides and IQ in 7-year-old childrenMaryse F Bouchard
University of California Berkeley, Center for Environmental Research and Children s Health, School of Public Health, Berkeley, California 94704, USA
Environ Health Perspect 119:1189-95. 2011..Organophosphate (OP) pesticides are neurotoxic at high doses. Few studies have examined whether chronic exposure at lower levels could adversely affect children's cognitive development... - Developmental changes in autonomic nervous system resting and reactivity measures in Latino children from 6 to 60 months of ageAbbey Alkon
Department of Family Health Care Nursing, School of Nursing, University of California, San Francisco, USA
J Dev Behav Pediatr 32:668-77. 2011..This study describes the developmental changes and individual stability in autonomic nervous system (ANS) resting and challenge responses for a cohort of primarily Latino, low-income children during the first 5 years of life... - Maternal prenatal and child organophosphate pesticide exposures and children's autonomic functionLesliam Quirós-Alcalá
Center for Environmental Research and Children s Health CERCH, School of Public Health, University of California, Berkeley, CA 94704, USA
Neurotoxicology 32:646-55. 2011..We hypothesized that children with high OP levels would show parasympathetic activation and no sympathetic activation during rest and concomitant parasympathetic and sympathetic activation during challenging conditions... - Pesticides and child neurodevelopmentLisa G Rosas
University of California at Berkeley, School of Public Health, Center for Children s Environmental Health Research, Berkeley, California, USA
Curr Opin Pediatr 20:191-7. 2008..This review summarizes the recent research on pesticide exposure and child neurobehavioral development with a focus on in-utero exposure to organochlorine and organophosphate pesticides... - Developmental changes in PON1 enzyme activity in young children and effects of PON1 polymorphismsKaren Huen
Center for Children s Environmental Health, School of Public Health, University of California, Berkeley, California, USA
Environ Health Perspect 117:1632-8. 2009..Paraoxonase 1 (PON1) is an enzyme that detoxifies activated organophosphorus pesticides (OPs) and is also involved in oxidative stress pathways... - Associations between prenatal exposure to polychlorinated biphenyls and neonatal thyroid-stimulating hormone levels in a Mexican-American population, Salinas Valley, CaliforniaJonathan Chevrier
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94704 7380, USA
Environ Health Perspect 115:1490-6. 2007..PCBs may in turn affect TH levels by inducing the microsomal enzyme uridinediphosphate glucuronosyltransferase (UDP-GT), which is involved in TH elimination... - Concentrations and loadings of polybrominated diphenyl ethers in dust from low-income households in CaliforniaLesliam Quirós-Alcalá
Center for Environmental Research and Children s Health CERCH, School of Public Health, University of California, 1995 University Avenue, Suite 265, Berkeley, CA 94704, USA
Environ Int 37:592-6. 2011..0 to 599ng/kg/day, 2.0-1065ng/kg/day and 0.5-196ng/kg/day for BDE-47, BDE-99 and BDE-100, respectively. In order to mitigate these exposures, future research must address the factors that contribute to PBDE exposures in low-income homes... - Dioxin exposure and cancer risk in the Seveso Women's Health StudyMarcella Warner
Center for Environmental Research and Children s Health, School of Public Health, University of California at Berkeley, Berkeley, California 94720, USA
Environ Health Perspect 119:1700-5. 2011..The International Agency for Research on Cancer classified TCDD as a known human carcinogen, based on predominantly male occupational studies of increased mortality from all cancers combined... - Assaying organochlorines in archived serum for a large, long-term cohort: implications of combining assay results from multiple laboratories over timeRobert I Sholtz
Child Health and Development Studies, Public Health Institute, Berkeley, CA 94709, USA
Environ Int 37:709-14. 2011..For PCB congeners with very low levels, findings caution against pooling of assays without further exploration... - Occupational behaviors and farmworkers' pesticide exposure: findings from a study in Monterey County, CaliforniaAlicia L Salvatore
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
Am J Ind Med 51:782-94. 2008.... - Cumulative organophosphate pesticide exposure and risk assessment among pregnant women living in an agricultural community: a case study from the CHAMACOS cohortRosemary Castorina
Center for Children's Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720, USA
Environ Health Perspect 111:1640-8. 2003..In future analyses, we will use pesticide-specific urinary metabolites, when available, to evaluate cumulative OP pesticide exposures... - Polybrominated diphenyl ether levels in the blood of pregnant women living in an agricultural community in CaliforniaAsa Bradman
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
Environ Health Perspect 115:71-4. 2007..Recent studies have raised concerns about polybrominated diphenyl ether (PBDE) flame retardant exposures to pregnant women and women of child-bearing age in the United States. Few studies have measured PBDEs in immigrant populations... - Uterine fibroids and gynecologic pain symptoms in a population-based studySheri A Lippman
School of Public Health, University of California at Berkeley, Berkeley, California 94720-7360, USA
Fertil Steril 80:1488-94. 2003..Fibroid-associated pain symptomatology in a non-care-seeking population may be different from that of a clinic population... - Validation of PON1 enzyme activity assays for longitudinal studiesKaren Huen
Center for Children s Environmental Health, School of Public Health, University of California, Berkeley, CA 94720 7360, United States
Clin Chim Acta 402:67-74. 2009..Length of sample storage, temperature and other factors may influence variability of PON1 measurements, especially in longitudinal studies... - Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidyCaihong Xing
Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA
Environ Health Perspect 118:833-9. 2010..Recent reports have identified health effects at exposure levels < 1 ppm, the permissible exposure limit (PEL; 8 hr) set by the U.S. Occupational Safety and Health Administration... - Factors associated with overweight and obesity among children of Mexican descent: results of a binational studyLisa G Rosas
Department of Family and Community Medicine, University of California, San Francisco, San Francisco, CA 94118, USA
J Immigr Minor Health 13:169-80. 2011..These data offer hypotheses for how migration may influence the high prevalence of overweight among the Mexican children in California... - Effect of antioxidant intake on sperm chromatin stability in healthy nonsmoking menElana W Silver
School of Public Health, University of California, Berkeley, California 94720-7380, USA
J Androl 26:550-6. 2005..The results of this study do not preclude possible beneficial effects of high antioxidant intake on sperm chromatin integrity for men with fertility problems... - Serum DDT and DDE levels in pregnant women of Chiapas, MexicoRuth Koepke
School of Public Health, University of California at Berkeley, Berkeley, California 94720-7360, USA
Arch Environ Health 59:559-65. 2004..This study provides evidence of high-level exposure to DDT and DDE among pregnant women living in Chiapas, Mexico, despite countrywide restrictions on its use at the time... - Dioxin-Like TEQ of women from the Seveso, Italy area by ID-HRGC/HRMS and CALUXMarcella Warner
School of Public Health, University of California at Berkeley, 94720, USA
J Expo Anal Environ Epidemiol 15:310-8. 2005..04, P=0.82). More validation of the CALUX bioassay with larger sample volume is needed before application as an exposure measure in large-scale epidemiologic studies of health effects of dioxin-like compounds... - The effect of time in the U.S. on the duration of breastfeeding in women of Mexican descentKim Harley
School of Public Health, UC Berkeley, 2150 Shattuck Ave, Suite 600, Berkeley, CA 94720 7380, USA
Matern Child Health J 11:119-25. 2007..S. is associated with poorer breastfeeding practices, including shorter duration of any and exclusive breastfeeding, in a population of low-income mothers of Mexican descent... - The association of time in the US and diet during pregnancy in low-income women of Mexican descentKim Harley
School of Public Health, University of California, Berkeley, CA 94720-7390, USA
Paediatr Perinat Epidemiol 19:125-34. 2005..A large percentage of women had inadequate intake of vitamin E (58%), folate (61%), iron (77%) and zinc (47%) from their diets during pregnancy and these rates were higher in US-born women than Mexico-born women... - Risk behaviors for pesticide exposure among pregnant women living in farmworker households in Salinas, CaliforniaLisa Goldman
Center for Children's Environmental Health Research, School of Public Health, University of California, Berkeley, California 94709, USA
Am J Ind Med 45:491-9. 2004..CONCLUSIONS: Pregnant farmworkers and those living with farmworkers need to be educated to reduce potential take-home pesticide exposure... - Measurement of pesticides and other toxicants in amniotic fluid as a potential biomarker of prenatal exposure: a validation studyAsa Bradman
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
Environ Health Perspect 111:1779-82. 2003..Results of this pilot study suggest that amniotic fluid offers a unique opportunity to investigate fetal exposures and health risks... - Association of housing disrepair indicators with cockroach and rodent infestations in a cohort of pregnant Latina women and their childrenAsa Bradman
Center for Children s Environmental Health Research, School of Public Health, University of California, Berkeley, California 94720 7380, USA
Environ Health Perspect 113:1795-801. 2005..Interventions to improve housing and promote children's health and safety in this population are needed... - Time in the United States, social support and health behaviors during pregnancy among women of Mexican descentKim Harley
University of California, Berkeley, Berkeley, CA, USA
Soc Sci Med 62:3048-61. 2006..Thus, in the case of diet quality, increased social support appears to prevent some of the negative pregnancy behaviors that accompany time in the US among women of Mexican descent... - Expression of Th1/Th2 cytokines in human blood after in vitro treatment with chlorpyrifos, and its metabolites, in combination with endotoxin LPS and allergen Der p1Paurene Duramad
Division of Environmental Health Sciences, School of Public Health, University of California, Berkeley, California 94720, USA
J Appl Toxicol 26:458-65. 2006..The interaction between CPO and LPS, which results in an increased type 1 immune response, should be investigated further, particularly since the combination of OP pesticides and endotoxin is common in rural, agricultural communities... - Maternal smoking, alcohol drinking, and febrile convulsionFarnaz Vahidnia
School of Public Health, University of California at Berkeley, Berkeley, CA 94720 7360, USA
Seizure 17:320-6. 2008..We evaluated the relationship of maternal smoking, alcohol drinking, and their interaction on febrile convulsion... - The ontogeny of autonomic measures in 6- and 12-month-old infantsAbbey Alkon
School of Nursing, University of California, San Francisco, CA 94143 0606, USA
Dev Psychobiol 48:197-208. 2006..Findings suggest that although infants' autonomic responses show developmental changes, individuals' rank order is stable from 6 to 12 months of age... - Polybrominated diphenyl ether (PBDE) flame retardants and thyroid hormone during pregnancyJonathan Chevrier
Center for Children s Environmental Health Research, School of Public Health, University of California Berkeley, Berkeley, California 94704 7392, USA
Environ Health Perspect 118:1444-9. 2010..Although thyroid hormone (TH) of maternal origin plays an essential role in normal fetal brain development, there is a paucity of human data regarding associations between exposure to PBDEs and maternal TH levels during pregnancy... - Children's intellectual function in relation to arsenic exposureOndine S von Ehrenstein
School of Public Health, University of California, Berkeley, California 94720 7360, USA
Epidemiology 18:44-51. 2007..Very little evidence exists concerning the possible impairment of children's intellectual function in relation to arsenic exposure in utero and during childhood... - Sex ratios in California following the terrorist attacks of September 11, 2001Ralph Catalano
School of Public Health, University of California at Berkeley, 94720, USA
Hum Reprod 20:1221-7. 2005.... - Biological sample collection and processing for molecular epidemiological studiesNina T Holland
School of Public Health, University of California, Berkeley, CA 94720 7360, USA
Mutat Res 543:217-34. 2003.... - Lysophosphatidylcholine hydrolases of human erythrocytes, lymphocytes, and brain: sensitive targets of conserved specificity for organophosphorus delayed neurotoxicantsSarah C Vose
Environmental Chemistry and Toxicology Laboratory, Department of Environmental Science, Policy and Management, 115 Wellman Hall, University of California, Berkeley, CA 94720 3112, USA
Toxicol Appl Pharmacol 224:98-104. 2007..The relative contributions of NTE and LysoPLAs to LysoPC hydrolysis and clearance from erythrocytes, lymphocytes, and brain remain to be defined... - Estimation of environmental tobacco smoke exposure during pregnancy using a single question on household smokers versus serum cotinineFarla Lynn Kaufman
Public Health Institute, Berkeley, California, USA
J Expo Anal Environ Epidemiol 12:286-95. 2002..Although use of this question alone does not provide an adequate estimation of ETS exposure as determined by serum cotinine, the results of this study indicate that this question is an important component of assessing ETS exposure... - Flow cytometric detection of intracellular TH1/TH2 cytokines using whole blood: validation of immunologic biomarker for use in epidemiologic studiesPaurene Duramad
Environmental Health Sciences, School of Public Health, University of California, Berkeley, California 94720-7360, USA
Cancer Epidemiol Biomarkers Prev 13:1452-8. 2004.... - Organochlorine pesticides and male genital anomalies in the child health and development studiesRajiv Bhatia
San Francisco Department of Public Health, San Francisco, California 94102, USA
Environ Health Perspect 113:220-4. 2005..0 ng/mL had adjusted odds ratios of 1.01 (95% CI, 0.44-2.28) for cryptorchidism and 0.79 (95% CI, 0.33-1.89) for hypospadias. This study does not support an association of DDT or DDE and hypospadias or cryptorchidism... - Principles and practices of neurodevelopmental assessment in children: lessons learned from the Centers for Children's Environmental Health and Disease Prevention ResearchKim N Dietrich
University of Cincinnati College of Medicine, Division of Epidemiology and Biostatistics, Department of Environmental Health, and the Cincinnati Children's Environmental Health Center, Cincinnati, Ohio, USA
Environ Health Perspect 113:1437-46. 2005..The human neurodevelopmental phenotype will be most clearly represented in models that include environmental chemical exposures, the social milieu, and complex human genetic characteristics that we are just beginning to understand... - Environmental Health Perspectives and children's environmental healthBrenda Eskenazi
Environ Health Perspect 110:A559-60. 2002 - PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivityClement E Furlong
Department of Genome Sciences, Division of Medical Genetics, University of Washington, Seattle, Washington 98195 7720, USA
Pharmacogenet Genomics 16:183-90. 2006..Of particular concern are exposures of pregnant mothers and newborns with low PON1 status... - Lessons learned for the National Children's Study from the National Institute of Environmental Health Sciences/U.S. Environmental Protection Agency Centers for Children's Environmental Health and Disease Prevention ResearchCarole A Kimmel
National Children's Study Interagency Coordinating Committee, National Center for Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency, Washington, DC, USA
Environ Health Perspect 113:1414-8. 2005..It is hoped that these articles will be of value to others who are embarking on studies of children's environmental health... - An approach to assessment of endocrine disruption in the National Children's StudyMatthew P Longnecker
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 111:1691-7. 2003..Nonetheless, if properly designed, the NCS could serve as an excellent resource for investigating future hypotheses regarding endocrine disruption... - Association of DDT and DDE with birth weight and length of gestation in the Child Health and Development Studies, 1959-1967Lili Farhang
San Francisco Department of Public Health, San Francisco, CA 94102, USA
Am J Epidemiol 162:717-25. 2005..27) for DDT; none of the study results achieved statistical significance. Given the persistence of DDT in the environment and its continuing role in malaria control, studies using more robust data should continue to assess this relation... - The faroes statement: human health effects of developmental exposure to chemicals in our environmentPhilippe Grandjean
Basic Clin Pharmacol Toxicol 102:73-5. 2008 - In utero exposure to DDT and performance on the Brazelton neonatal behavioral assessment scaleLaura Fenster
California Department of Health Services, Division of Environmental and Occupational Disease Control, 850 Marina Bay Parkway, Richmond, CA 94804 6403, USA
Neurotoxicology 28:471-7. 2007..The failure to observe effects on the BNBAS in these same children may be due to limited sensitivity of a single BNBAS assessment or a delay in the manifestations of neurodevelopmental effects of DDT/DDE until after the neonatal period... - Association of in utero organochlorine pesticide exposure and fetal growth and length of gestation in an agricultural populationLaura Fenster
Division of Environmental and Occupational Disease Control, California Department of Health Services, Richmond, CA 94804, USA
Environ Health Perspect 114:597-602. 2006..Our finding of decreased length of gestation related to HCB does not seem to have had clinical implications for this population, given its relatively low rate of preterm delivery (6.5%)... - Children's health and the environment: public health issues and challenges for risk assessmentPhilip J Landrigan
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, New York 10029, USA
Environ Health Perspect 112:257-65. 2004..The adequate protection of children against toxic agents in the environment will require fundamental and far-reaching revisions of current approaches to toxicity testing and risk assessment... - Environmental tobacco smoke and pregnancy outcomeMartin Kharrazi
Genetic Disease Branch, California Department of Health Services, Richmond, California 94804, USA
Epidemiology 15:660-70. 2004..However, the threshold and magnitude of that effect is uncertain. We aimed to determine the magnitude and shape of the relations between ETS and various adverse pregnancy outcomes using a highly sensitive biochemical assay... - Psychological distress during early gestation and offspring sex ratioCarsten Obel
Department of General Practice, Institute of Public Health, University of Aarhus, 8000, Aarhus C, Denmark
Hum Reprod 22:3009-12. 2007..In a population based follow-up study, we aimed to test whether psychological distress was associated with the sex ratio in the offspring... - Effects of male age on the frequencies of germinal and heritable chromosomal abnormalities in humans and rodentsEddie Sloter
Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, California 94550, USA
Fertil Steril 81:925-43. 2004....
Research Grants
- Female Reproductive Outcomes and TCDD Exposure in SevesoBrenda Eskenazi; Fiscal Year: 2007..This study has the benefit of being a large cohort study with a wide range of TCDD exposure, documented by individual-level TCDD measured in sera collected soon after the explosion. ..
- Health Outcomes and Dioxin Exposure of Women and Children in SevesoBrenda Eskenazi; Fiscal Year: 2007..This study has the benefit of being a large cohort study with a wide range of TCDD exposure, documented by individual-level TCDD measured in sera collected soon after the explosion. ..
- PBDEs, DDT and Neurodevelopment in School-Aged Mexican-American ChildrenBrenda Eskenazi; Fiscal Year: 2007....
- Center for Children's Environmental Health ResearchBrenda Eskenazi; Fiscal Year: 2007..ultimate goal: to translate research findings into sustainable strategies to reduce pesticide and other environmental exposures to children, and thus reduce the incidence of environmentally-related childhood disease ..
- PBDEs, DDT and Neurodevelopment in School-Aged Mexican-American ChildrenBrenda Eskenazi; Fiscal Year: 2010....
- DDT & PBDE exposure, puberty onset and neurodevelopment in Mexican-American girlsBrenda Eskenazi; Fiscal Year: 2010....
- Genetic damage in the sperm and blood of workers exposed to benzeneBrenda Eskenazi; Fiscal Year: 2007..Lastly, this study is one of the first to investigate the relative sensitivities of sperm and blood cells to chromosomal defects induced by benzene. ..
- Reducing pesticide exposures to farmworker children.Brenda Eskenazi; Fiscal Year: 2005....
- Endocrine Disruptors and Neurodevelopmental OutcomesBrenda Eskenazi; Fiscal Year: 2004..This study will provide the first data on exposure and health effects of ED pesticides in a highly exposed population, complete the exposure profile of CHAMACOS children, and target interventions to reduce child exposures. ..
- FEMALE REPRODUCTIVE OUTCOMES AND TCDD EXPOSUREBrenda Eskenazi; Fiscal Year: 2001....
- Health Outcomes and Dioxin Exposure of Women and Children in SevesoBrenda Eskenazi; Fiscal Year: 2010..This study has the benefit of being a large cohort study with a wide range of TCDD exposure, documented by individual-level TCDD measured in sera collected soon after the explosion. ..