Adrien A Eshraghi

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. doi request reprint Dexamethasone base conserves hearing from electrode trauma-induced hearing loss
    Richard J Vivero
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, Florida 33136 1015, USA
    Laryngoscope 118:2028-35. 2008
  2. ncbi request reprint Molecular mechanisms involved in cochlear implantation trauma and the protection of hearing and auditory sensory cells by inhibition of c-Jun-N-terminal kinase signaling
    Adrien A Eshraghi
    University of Miami Hearing Research Laboratory, Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida 33136 1015, USA
    Laryngoscope 123:S1-14. 2013
  3. doi request reprint Biomedical engineering principles of modern cochlear implants and recent surgical innovations
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Miller School of Medicine, University of Miami Ear Institute, Miami, Florida 33136 1015, USA
    Anat Rec (Hoboken) 295:1957-66. 2012
  4. doi request reprint The cochlear implant: historical aspects and future prospects
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Ear Institute, University of Miami Miller School of Medicine, Miami, Florida 33136 1015, USA
    Anat Rec (Hoboken) 295:1967-80. 2012
  5. ncbi request reprint Prevention of cochlear implant electrode damage
    Adrien A Eshraghi
    University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA
    Curr Opin Otolaryngol Head Neck Surg 14:323-8. 2006
  6. ncbi request reprint [Hearing loss in adults]
    Adrien A Eshraghi
    University of Miami Miller School of Medicine, Miami, FL, USA
    Rev Prat 59:645-52. 2009
  7. doi request reprint Cochlear implant surgery in patients more than seventy-nine years old
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Laryngoscope 119:1180-3. 2009
  8. ncbi request reprint Changes in programming over time in postmeningitis cochlear implant users
    Adrien A Eshraghi
    University of Miami School of Medicine, Department of Otolaryngology, University of Miami Eear Institute, Florida, USA
    Otolaryngol Head Neck Surg 131:885-9. 2004
  9. ncbi request reprint Mechanisms of hearing loss from trauma and inflammation: otoprotective therapies from the laboratory to the clinic
    Thomas R Van De Water
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, FL 33136 1015, USA
    Acta Otolaryngol 130:308-11. 2010
  10. ncbi request reprint D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation trauma
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Ear Institute, Miami, Florida 33136 1015, USA
    Otol Neurotol 27:504-11. 2006

Collaborators

Detail Information

Publications42

  1. doi request reprint Dexamethasone base conserves hearing from electrode trauma-induced hearing loss
    Richard J Vivero
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, Florida 33136 1015, USA
    Laryngoscope 118:2028-35. 2008
    ..Local treatment of the cochlea after electrode insertion trauma with dexamethasone base conserves hearing against trauma-induced loss...
  2. ncbi request reprint Molecular mechanisms involved in cochlear implantation trauma and the protection of hearing and auditory sensory cells by inhibition of c-Jun-N-terminal kinase signaling
    Adrien A Eshraghi
    University of Miami Hearing Research Laboratory, Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida 33136 1015, USA
    Laryngoscope 123:S1-14. 2013
    ..To investigate the molecular mechanisms involved in electrode insertion trauma (EIT) and to test the otoprotective effect of locally delivered AM-111...
  3. doi request reprint Biomedical engineering principles of modern cochlear implants and recent surgical innovations
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Miller School of Medicine, University of Miami Ear Institute, Miami, Florida 33136 1015, USA
    Anat Rec (Hoboken) 295:1957-66. 2012
    ..Advances in biomedical engineering and surgical innovations that lead to an increasingly favorable clinical outcome and to an expansion of the indication of CI surgery are presented and discussed...
  4. doi request reprint The cochlear implant: historical aspects and future prospects
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Ear Institute, University of Miami Miller School of Medicine, Miami, Florida 33136 1015, USA
    Anat Rec (Hoboken) 295:1967-80. 2012
    ..Although great progress has been made to date in the development of the CI, including the first substantial restoration of a human sense, much more progress seems likely and certainly would not be a surprise...
  5. ncbi request reprint Prevention of cochlear implant electrode damage
    Adrien A Eshraghi
    University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA
    Curr Opin Otolaryngol Head Neck Surg 14:323-8. 2006
    ..This article summarizes current research endeavors to prevent electrode insertion trauma and resulting hearing loss...
  6. ncbi request reprint [Hearing loss in adults]
    Adrien A Eshraghi
    University of Miami Miller School of Medicine, Miami, FL, USA
    Rev Prat 59:645-52. 2009
    ..Antioxidant molecules, molecules against apoptosis are at this time the most promising molecules than need further investigations...
  7. doi request reprint Cochlear implant surgery in patients more than seventy-nine years old
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Laryngoscope 119:1180-3. 2009
    ..To evaluate the surgical complications, auditory performance, and hearing handicap following cochlear implantation in patients greater than 79 years of age...
  8. ncbi request reprint Changes in programming over time in postmeningitis cochlear implant users
    Adrien A Eshraghi
    University of Miami School of Medicine, Department of Otolaryngology, University of Miami Eear Institute, Florida, USA
    Otolaryngol Head Neck Surg 131:885-9. 2004
    ..This study evaluated changes in programming for patients deafened by bacterial meningitis and stability of auditory performance over time...
  9. ncbi request reprint Mechanisms of hearing loss from trauma and inflammation: otoprotective therapies from the laboratory to the clinic
    Thomas R Van De Water
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, FL 33136 1015, USA
    Acta Otolaryngol 130:308-11. 2010
    ..Locally delivered dexamethasone is a promising therapeutic approach for the conservation of hearing during the process of cochlear implantation...
  10. ncbi request reprint D-JNKI-1 treatment prevents the progression of hearing loss in a model of cochlear implantation trauma
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Ear Institute, Miami, Florida 33136 1015, USA
    Otol Neurotol 27:504-11. 2006
    ....
  11. doi request reprint Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms
    Thomas R Van De Water
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33136 1015, USA
    Cochlear Implants Int 11:42-55. 2010
    ..Dexamethasone (DXM) protects hearing against trauma-induced loss...
  12. ncbi request reprint Pattern of hearing loss in a rat model of cochlear implantation trauma
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami Leonard M Miller School of Medicine, Miami, Florida, USA
    Otol Neurotol 26:442-7; discussion 447. 2005
    ..Trauma caused by cochlear implant electrode insertion is attributable to the combination of direct physical trauma and the delayed cell death of oxidative stress-injured auditory sensory cells...
  13. ncbi request reprint Conservation of residual acoustic hearing after cochlear implantation
    Thomas J Balkany
    Department of Otolaryngology, University of Miami Ear Institute, Miller School of Medicine, Miami, Florida 33101, USA
    Otol Neurotol 27:1083-8. 2006
    ..Surgical strategies for hearing conservation during cochlear implantation are described...
  14. ncbi request reprint Blocking c-Jun-N-terminal kinase signaling can prevent hearing loss induced by both electrode insertion trauma and neomycin ototoxicity
    Adrien A Eshraghi
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami Miller School of Medicine, 1600 NW 10th Avenue, RMSB 3160, Miami, FL 33136 1015, USA
    Hear Res 226:168-77. 2007
    ..This unique therapeutic approach may have clinical application for preventing: (1) hearing loss caused by neomycin ototoxicity; and (2) the progressive component of electrode insertion trauma-induced hearing loss...
  15. ncbi request reprint Triamcinolone acetonide protects auditory hair cells from 4-hydroxy-2,3-nonenal (HNE) ototoxicity in vitro
    Jose Guzman
    University of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine University of Miami, Miami, FL 33136, USA
    Acta Otolaryngol 126:685-90. 2006
    ..e. 4-hydroxy-2,3-nonenal (HNE), that is produced within the organ of Corti as a result of oxidative stress-induced damage...
  16. doi request reprint Dexamethasone treatment of naïve organ of Corti explants alters the expression pattern of apoptosis-related genes
    Kimberly N Hoang
    University of Miami Ear Institute, Department of Otolaryngology, University of Miami, FL 33136 1015, USA
    Brain Res 1301:1-8. 2009
    ..It is not known if naïve organ of Corti explants will respond in a similar manner to treatment with a corticosteroid. This study examines the response of naïve organ of Corti explants to treatment with dexamethasone...
  17. ncbi request reprint Local dexamethasone therapy conserves hearing in an animal model of electrode insertion trauma-induced hearing loss
    Adrien A Eshraghi
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, Miller School of Medicine, University of Miami, Miami, FL, USA
    Otol Neurotol 28:842-9. 2007
    ..The progressive loss of hearing that develops after electrode insertion trauma (EIT) can be attenuated by local dexamethasone (DXM) therapy...
  18. doi request reprint Biopolymer-released dexamethasone prevents tumor necrosis factor alpha-induced loss of auditory hair cells in vitro: implications toward the development of a drug-eluting cochlear implant electrode array
    Christine Dinh
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, Florida, USA
    Otol Neurotol 29:1012-9. 2008
    ..Polymer-eluted dexamethasone (DXM) will retain its ability to protect against tumor necrosis factor alpha (TNFalpha)-induced hair cell (HC) loss...
  19. ncbi request reprint Cochlear temperature correlates with both temporalis muscle and rectal temperatures. Application for testing the otoprotective effect of hypothermia
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami, Miami, Florida 33136, USA
    Acta Otolaryngol 125:922-8. 2005
    ....
  20. doi request reprint The temporalis pocket technique for cochlear implantation: an anatomic and clinical study
    Thomas J Balkany
    University of Miami Ear Institute Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA
    Otol Neurotol 30:903-7. 2009
    ..Newer R/S designs feature a low profile and larger, rigid flat bottoms in which drilling a seat may be less appropriate. We report a technique for securing the R/S without drilling bone...
  21. ncbi request reprint Mild hypothermia protects auditory function during cochlear implant surgery
    Thomas J Balkany
    Department of Otolaryngology, University Ear Institute, Leonard M Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Laryngoscope 115:1543-7. 2005
    ..We hypothesize that hypothermia has a similar protective effect against loss of auditory function caused by CI electrode insertion trauma...
  22. ncbi request reprint Evaluation of hearing and auditory nerve function by combining ABR, DPOAE and eABR tests into a single recording session
    Marek Polak
    Department of Otolaryngology, Cochlear Implant Research Program, University of Miami Ear Institute, 1600 NW 10th Avenue, RMSB 3160, Miami, FL 33136, USA
    J Neurosci Methods 134:141-9. 2004
    ..All measurements were obtained from anesthetized laboratory rats during single recording sessions using hardware and software stimulation and analysis programs developed by Intelligent Hearing Systems, Miami, FL...
  23. ncbi request reprint Dexamethasone and methylprednisolone do not inhibit neuritic outgrowth while inhibiting outgrowth of fibroblasts from spiral ganglion explants
    Alexis Furze
    Department of Otolaryngology, University of Miami Ear Institute, Miller School of Medicine, Miami, FL, USA
    Acta Otolaryngol 128:122-7. 2008
    ..Dexamethasone and methylprednisolone do not inhibit neuritic outgrowth while inhibiting fibroblastic outgrowth from spiral ganglion micro-explants...
  24. ncbi request reprint Electrode migration after cochlear implantation
    Sarah S Connell
    Department of Otolaryngology, University of Miami Ear Institute, Miami, Florida, USA
    Otol Neurotol 29:156-9. 2008
    ..To review the occurrence of electrode migration after cochlear implantation...
  25. doi request reprint Cochlear implantation in organ transplantation
    D Michael Patterson
    Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL 33101, USA
    Laryngoscope 118:116-9. 2008
    ..This study was designed to retrospectively review the outcomes of cochlear implantation among organ transplant patients...
  26. ncbi request reprint Partial medial canal fibrosis
    Adrien A Eshraghi
    University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, USA
    Ear Nose Throat J 85:75. 2006
  27. ncbi request reprint Glutathione ester protects against hydroxynonenal-induced loss of auditory hair cells
    Jose W Ruiz
    University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Leonard M Miller School of Medicine, Miami, Florida, USA
    Otolaryngol Head Neck Surg 135:792-7. 2006
    ..Test the ability of glutathione monoethyl ester (GSH(e)) to protect auditory hair cells against the ototoxic effects of 4-hydroxy-2,3-nonenal (HNE)...
  28. doi request reprint The perceived angle of the round window affects electrode insertion trauma in round window insertion - an anatomical study
    Yisgav Shapira
    University of Miami Ear Institute, Department of Otolaryngology, University of Miami Miller School of Medicine, FL, USA
    Acta Otolaryngol 131:284-9. 2011
    ..6% of cases. Therefore RW insertion is a valid option to be considered in selected cochlear implant patients, especially when hearing preservation is a goal. In most cases drilling of the overhangs is required...
  29. ncbi request reprint Induction of localized cochlear hypothermia
    Lee P Smith
    Department of Otolaryngology, Leonard M Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Acta Otolaryngol 127:228-33. 2007
    ..Localized cochlear hypothermia was induced in a rat model, demonstrating the feasibility of modulating cochlear temperature without affecting core body temperature...
  30. ncbi request reprint Modiolar proximity of three perimodiolar cochlear implant electrodes
    Thomas J Balkany
    University of Miami Ear Institute, Florida 33136, USA
    Acta Otolaryngol 122:363-9. 2002
    ..All three devices were successful in terms of locating electrode contacts very close to the modiolar wall...
  31. ncbi request reprint Comparative study of cochlear damage with three perimodiolar electrode designs
    Adrien A Eshraghi
    Department of Otolaryngology, Medical School, University of Miami Ear Institute, Miami, FL 33131, USA
    Laryngoscope 113:415-9. 2003
    ..To describe intracochlear insertion trauma caused by three perimodiolar cochlear implant electrodes...
  32. ncbi request reprint Cochlear implants in children--a review
    Thomas J Balkany
    Department of Otolaryngology, University of Miami Ear Institute, Florida 33101, USA
    Acta Otolaryngol 122:356-62. 2002
    ..Hearing, language and social development outcomes have been positive. We review current issues in cochlear implantation, candidacy, evaluation, surgery, habilitation, ethics and outcomes...
  33. ncbi request reprint Dexamethasone protects auditory hair cells against TNFalpha-initiated apoptosis via activation of PI3K/Akt and NFkappaB signaling
    Scott M Haake
    Cochlear Implant Research Program, University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, RMSB 3160, Miami, FL 33136 1015, USA
    Hear Res 255:22-32. 2009
    ..Local treatment of cochleae of trauma-exposed animals with a glucocorticoid is effective in reducing the level of hearing loss that occurs post-trauma (e.g., electrode insertion trauma-induced hearing loss/dexamethasone treatment)...
  34. ncbi request reprint Cochlear implantation trauma and noise-induced hearing loss: Apoptosis and therapeutic strategies
    Adrien A Eshraghi
    University of Miami Ear Institute, Department of Otolaryngology, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA
    Anat Rec A Discov Mol Cell Evol Biol 288:473-81. 2006
    ..g., electrode array insertional trauma. These forward-looking strategies have the potential of improving hearing outcomes after cochlear implantation and providing novel means of otoprotection from noise-induced trauma...
  35. doi request reprint Middle fossa vestibular neurectomy for refractory vertigo: less is more
    Simon I Angeli
    Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, Florida, USA
    Ann Otol Rhinol Laryngol 123:359-64. 2014
    ..This study aimed to evaluate outcomes of the middle fossa (MF) superior vestibular neurectomy in unilateral Ménière's disease...
  36. ncbi request reprint Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation
    Ulysses Scarpidis
    Department of Otolaryngology, Albert Einstein College of Medicine, Bronx, New York, USA
    Otol Neurotol 24:409-17. 2003
    ..The JNK/c-Jun cell death pathway is a major pathway responsible for the loss of oxidative stress-damaged auditory neurons...
  37. ncbi request reprint Tympanomeatal flaps
    Thomas J Balkany
    Department of Otolaryngology, University of Miami Ear Institute, Box 016960 D 48, Miami, FL 33101, USA
    Laryngoscope 113:1266-8. 2003
  38. ncbi request reprint Complete medial canal fibrosis
    S Arif Ulubil
    University of Miami Ear Institute, Department of Otolaryngology, University of Miami Miller School of Medicine, USA
    Ear Nose Throat J 85:10. 2006
  39. pmc Otoplasty for the protruded ear
    Ronen Nazarian
    Department of Otolaryngology, Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, Florida
    Semin Plast Surg 25:288-94. 2011
    ..They also describe in more detail some of the more common methods for correcting the protruded ear, as well as postoperative management and common complications faced after surgery...
  40. ncbi request reprint Sensory auricular branch of the facial nerve
    Adrien A Eshraghi
    Department of Otolaryngology, University of Miami School of Medicine, Miami, Florida, USA
    Otol Neurotol 23:393-6. 2002
    ..To better describe the anatomy of the sensory auricular branch of the facial nerve...
  41. ncbi request reprint Caloric function after endolymphatic sac surgery
    S Arif Ulubil
    Department of Otolaryngology, Kocaeli University Faculty of Medicine, Kocaeli, Turkey
    Laryngoscope 118:295-9. 2008
    ..To evaluate the effect of endolymphatic sac surgery on vestibular functions using caloric testing on electronystagmography (ENG)...
  42. ncbi request reprint Vibrant soundbridge surgery: evaluation of transcanal surgical approaches
    Eric Truy
    Département d ORL, de Chirurgie Maxillo Cervico Faciale et d Audiophonologie, Hopital Edouard Herriot, Lyon, France
    Otol Neurotol 27:887-95. 2006
    ..e., facial palsy and/or taste disturbance. The purpose of this study is to develop and compare transcanal surgical approaches for leading the VSB into the middle ear...